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Activity 10
Crosses Involving Incomplete Dominance (Genetics)

Terms:
Incomplete dominance- dominant allele does not completely mask the effects of recessive allele
Homozygous- when both alleles in a homologous chromosome pair have the same expression
Heterozygous- when the alleles differ in their expression

I- Introduction:
The concept of dominance and recessiveness are somewhat arbitrary and artificial in
some instances because so-called dominant genes may be expressed differently in
homozygous and heterozygous individuals. This produces a condition called incomplete
dominance. In such case, both alleles express themselves in the offspring. Heterozygous
offspring exhibit a phenotype intermmediate between that of the homozygous individuals.

II- Objectives: (Students will);


a. Determine the possible genotype of the offspring using Punnett square.
b. Record the percentages/ratio of both genotype and phenotype.

III- Materials:
Textbook, pencil, calculator

IV- Instructions and Questions:


SS: normal hemoglobin gene; ss: double dose sickling gene; Ss: normal & sickling hemoglobin
1. Work out the following crosses:
A. Parental Genotypes: SS x ss

B. Parental Genotypes: Ss x Ss

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V- References:

Marieb, E., Mitchell, S., and Smith L., (2014). Human Anatomy and Physiology Laboratory
Manual. Paerson Education South Asia Pte. Ltd., 10th ed., pp. 709

Seeley, R., Stephens, T., and Tate, P., (2007). Essentials of Anatomy & Physiology. The
McGraw-Hill Companies, Inc. 6th ed., pp. 596-598.

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