A Case Study on Graves Disease

In Partial Fulfillment of the Course Requirement in Immunology Serology And

Blood Banking

Submitted to:
Archie F. Anadon, RMT

Submitted by:
Rovic Rogel Joy D. Hisola

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 CHAPTER 1

INTRODUCTION

A 35 year old nurse complained of nervousness, mood swings, weakness, and

palpitations with exertion for the past 6 months. Recently, she noticed excessive
sweating and wanted to sleep with fewer blankets than her husband. She used oral
contraceptives and her menstrual periods were regular.

Physical examination:
Pulse was 92/minute and BP was 130/60. She appeared anxious, with a smooth,
warm, and moist skin, a fine tremor, a bounding cardiac apical impulse, and she
couldn't rise from a deep knee bend without aid. Her thyroid was diffusely enlarged,
soft, mobile, without nodularity and there was no lymphadenopathy. Her eyes were
not prominent (proptotic) and she had no focal skin thickening.

Laboratory results:
Serum T4=15.6 ug/dl
serum T3=210 ng/dl.

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 CHAPTER 2

Personal data:
Name: N/A
Age: 35 year old
Gender: Female
Address: N/A
Relationship status: Married

Medical History:
 Nervousness, mood swings, weakness, and palpitations with exertion for the
past 6 months.
 Recently, she noticed excessive sweating and wanted to sleep with fewer
blankets than her husband.
 Used oral contraceptives and her menstrual periods were regular.

Laboratory results:
 Serum T4 = 15.6 ug/dl
 Serum T3 = 210 ng/dl

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 CHAPTER 3

DEFINITION OF THE CASE

Anatomy and Physiology

Pathophysiology
Graves disease is characterized by hyperthyroidism. It is the Common cause of
hyperthyroidism, affecting approximately 0.5 percent of the population. It is also the
most prevalent autoimmune disorder in the United States.

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