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Trade Name: Innovar

Classification: General anesthetic, narcotic analgesic, neuroleptic


analgesic

PHARMOCOLOGY Use(s): Premedication, adjunct/maintenance of anesthesia,

Action: Acts at subcortical levels to reduce motor activity.

DRUG CARDS Contraindications: Hypersensitivity, <2 years old.

Side Effects: Laryngospasm, bronchospasm, respiratory arrest.

Nursing implications: V/S, LFT, BUN, Creatine, Paco2. After 1st dose
of narcotic reduce dosage.

Trade Name: Progesterone Trade Name: Estrogens


Classification: Progesterone, hormone Classification: Estrogen, hormone

Use(s): Contraception, amenorrhea, PMS, abnormal uterine bleeding. Use(s): Menopause, inoperable breast CA, Prostate CA, osteoporosis

Action: Prevents pituitary release of gonadotrophins, which prevents Action: Inhibits release of pituitary gonadotrophins, inhibits ovulation
follicular maturation. and calcium use in bone.

Contraindications: Breast/Reproductive CA, , cerebral bleeds. Contraindications: Breast/Reproductive CA

Side Effects: Stroke, PE, MI, spontaneous AB Side Effects: Seizures, Stroke, MI

Nursing implications: Weight, B/P, LFT, edema, mental status, Nursing implications: Assess LFT, AST, ALT, bilirubin.
hypercalcemia.
Trade Name: Rocephin (ceftriaxone)
Trade Name: Doxycycline
Classification: Broad-Spectrum antibiotic, 3rd generation cephalosporin
Classification: Antiinfectives
Use(s): Gram-negative bacilli, less effective against gram positive
Use(s): syphilis, Clap, gonorrhea, rickettsia
Action: Inhibits bacterial cell wall synthesis
Action: Inhibits protein synthesis
Contraindications: to cephalosporins, <1 month old, pregnancy,
lactation. Contraindications: hypersensitivity to tetracycline, children <8 years
old, pregnancy, lactation.
Side Effects: N/V/D, bleeding, proteinuria, lymphocytosis, super
infection, headache, dizziness, rash Side Effects: Fever, neutropenia, angioedema, hepatotoxicity

Nursing implications: Sensitivity to PCN or other cephalosporins. Nursing implications: Assess I&O, allergic Rx, Blood studies, Signs
Assess for diarrhea, and blood chemistry studies, assess for s/s of of infection.
superifection such as thrush and yeast infection

Trade Name: Tetracycline Trade Name: Penicillin


Classification: Broad-Spectrum anti-infective Classification: Broad-Spectrum antiinfectives.

Use(s): Syphilis, clap, gonorrhea, rickettsia infections, acne, Use(s): Gram +/- bacilli and cocci.
ophthalmic neonatorum
Action: interferes with cell wall replication, producing inferior cell walls.
Action: Inhibits protein synthesis
Contraindications: Hypersensitivity to PCN, neonates. Sensitivity to
Contraindications: hypersensitivity to tetracycline, children <8 years cephalosporins
old, pregnancy, and lactation. Hypersensitivity to light
Side Effects: anemia, increased bleeding time, Oliguria, proteinuria,
Side Effects: Fever, HA, neutropenia, hemolytic anemia, angioedema. Hematuria, rash, uticaria, anaphylaxsis

Nursing implications: Signs of anemia, Allergic reactions, N/V/D. Nursing implications: Infection, I&O, liver studies, blood studies,
Store out of heat/light respiratory status.
Trade Name: Acyclovir
Trade Name: Podophyllin
Classification: Antiviral
Classification: Antiviral
Use(s): Herpes zoster, herpes simplex, herpes genitalis
Use(s): Genital wart removal
Action: Interferes with DNA synthesis causing decreased viral
replication. Action: unknown

Contraindications: Contraindications: hypersensitivity; perianal or MM warts.

Side Effects: Tremors, confusion, lethargy, convulsions, acute renal Side Effects: inflammation, burning
failure.
Nursing implications: None noted.
Nursing implications: Signs of infection, I&O ratio, skin eruptions,
allergic Reactions

Trade Name: Flagyl (Metronidazole HCL)


Classification: Antiinfectives Trade Name: Pepcid

Use(s): Intestinal amoeba, bone / joint infections, lower respiratory Classification: H2-receptor antagonist.
infections. Trichomonas vaginalis
Use(s): Duodenal ulcer, gastric ulcer, GERD
Action: Direct acting amebicide
Action: Competitively inhibits histamine, while pepsin stays at a stable
st
Contraindications: , renal disease, pregnancy (1 tri), CNS disorders. level, inhibits gastric secretions

Side Effects: Headache, dizziness, convulsions, Blurred vision, sore Contraindications: Hypersensitivity
throat, dry mouth.
Side Effects: Thrombocytopenia, seizure, bronchospasm,
Nursing implications: Assess for signs of infection. Assess stools,
check vision, allergic reactions. Nursing implications: Blood counts, bleeding
Trade Name: Tobramycin Trade Name: Neomycin
Classification: Antiinfectives-Aminoglycoside Classification: Antiinfectives-Aminoglycoside

Use(s): Severe systemic infections with pseudomonas, E.Coli,


Use(s): Infections of pseudomonas, E.Coli, enterobacter, enterobacter, Proteus.
staphylococcus
Action: Interferes with protein synthesis by binding to the 30s
Action: Interferes with protein synthesis, causing an inaccurate peptide subunit, causing an erroneous protein that causes death.
sequence resulting in death.
Contraindications: Bowel obstruction, severe renal disease,
Contraindications: Severe renal disease, hypersensitivity to hypersensitivity, infants, and children.
aminoglycosides.
Side Effects Oliguria, hematuria, renal failure, ototoxicity,
Side Effects Oliguria, hematuria, renal failure, ototoxicity, nephrotoxicity, & leukopenia.
nephrotoxicity, & leukopenia.
Nursing implications: Assess Weight, I&O, renal impairment,
Nursing implications: Assess weight, I&O, blood studies, serum dehydration, blood studies, serum levels.
levels

Trade/generic: Zinacef (cefuroxime sodium) Trade Name: Claforan


Class: Antibacterial Agents: 2nd gen. Cephalosporin Classification: Broad-spectrum antibiotic-Cephalosporin

Route: IM, IV Use(s): Gram - & gram + organisms

Ind: Gram +/- bacteria, including most staph, gp. A & B Action: Inhibits cell wall synthesis, making cell wall unstable.
Strep, most strep, E. coli, meningitits.
Contraindications: hypersensitivity to cephalosporins, infants < 1
Action: Inhibits bacterial cell wall synthesis, making the month.
cell wall unstable.
Side Effects: N/V/D, anaphylaxis, Proteinuria, leukopenia.
Contra: Hypers, seizure disorders.
Nursing implications: Assess for sensitivity to PCN/Cephalosporins,
S/E: Dizziness, headache, fatigue, rash, nephrotoxicity, blood studies, and electrolytes.
nephrotoxicity, renal failure.

RN: Assess for nephrotoxicity, I&O, Blood serum


studies & allergic reactions.
Trade Name: Tazidime Trade Name: Erythromycin
Classification: Broad-Spectrum Antiinfectives-Microlide
Classification: Broad-spectrum antibiotic-Cephalosporin
Use(s): Bacterial infections, Legionaire’s disease, syphilis.
Use(s): Gram negative and gram positive organisms
Action: Binds to P site of 50s ribosomal subunit, interfereing w/
Action: Inhibits cell wall synthesis, making cell wall unstable.
protein synthesis.
Contraindications: hypersensitivity to cephalosporins, infants < 1
Contraindications: Hypersens., cisapride use, astemizole use,
month.
impaired liver function, impaired hearing.
Side Effects: N/V/D, anaphylaxis, Proteinuria, leukopenia.
Side Effects: anaphylaxis, N/V, diarrhea, anorexia, abd pain, abd
cramps, pruritus,
Nursing implications: Assess for sensitivity to PCN/Cephalosporins,
nephrotoxicity, blood studies, and electrolytes.
Nursing implications: observe for allergic reactions,

Trade Name: Ticar (ticarcillin) Trade Name: Ampicillin


Classification: Broad-spectrum Antiinfectives-Penicillin Classification: Broad-Spectrum Antiinfectives-Penicillin

Use(s): Gram +/- cocci, Gram +/- bacilli. Use(s): Gram +/- cocci, Gram +/- bacilli

Action: Interferes with cell wall replication, and causes unstable cell Action: Interferes with cell wall replication & causes cell walls to
walls to burst. burst.

Contraindications: Hypersensitivity to PCN Contraindications: Hypersensitivity to PCN

Side Effects: Anemia, increased bleeding time, bone marrow Side Effects: Rash, anemia, bone marrow depression, coma,
depression, N/V/D. convulsions, and anaphylaxis.

Nursing implications: Assess, I&O, liver studies, blood studies, Nursing implications: Assess I&O, liver studies, blood studies,
lethargy, coma, convulsions. respiratory and vitals, as well as bowel habits.
Trade Name: Cipro Trade Name: Bactrim
Classification: Broad-Spectrum Antiinfectives Classification: Antiinfectives-Sulfonamides

Use(s): Infections caused by susceptible organisms E. Coli, Proteus, Use(s): UTI, Otitis media, and shigellosis
staph.
Action: Bacteriostatic agent that prevents bacterial growth by
Action: Interferes with conversion of DNA fragments into higher Inhibiting folic acid production.
molecular weight ones. DNA gyrase inhibitors.
Contraindications: Hypersensitivity to sulfonamides, infants <2
Contraindications: Hypersensitivity to quinolones months.

Side Effects: Headache, dizziness, restlessness, N/V/D. Side Effects: N/V, diarrhea, joint pain, urticaria, convulsions, fever,
renal failure, leukopenia.
Nursing implications: Assess for CNS symptoms, I&O ratio, allergic
reactions. Nursing implications: Assess for allergic reactions, kidney functions,
and allergic reactions, maintain adequate fluid inake

Trade Name: Virazole (ribavirin) Trade Name: Respigam


Classification: Antiviral Agents-ribavirin Classification: Immune serums

Use(s): Infants and young children w/ lower resp. infections caused Use(s): Prevention of serious lower respiratory tract infections
By RSV (respiratory syncytial virus) caused by RSV in children <2 years old, with bronchopulmonary
dysplasia, or premature birth.
Action: Inhibits viral RNA and DNA synthesis
Action: Higher titer of neutralizing antibody against RSV.
Contraindications: Pregnant or lactating, COPD, asthma, ventilation,
Contraindications: Hypersensitivity to this drug or other human
Side Effects:  resp. function, vent. Dependence, pneumothorax, immunoglobulin preparations.
apnea, cardiac arrest, HTN, rash, conjunctivitis, erythema of eyelids.
Side Effects: Resp distress, hypoxia, fever, HTN, anaphylaxis
Nursing implications: Monitor: VS, cardiac status, CBC. Route of
administration is aerosol inhalation Nursing implications: Assess vital signs, respiratory status, for
signs of aseptic meningitis.
Trade Name: Synagis Trade Name: antimycotic Agents (nystatin,
clotrimazole, miconazole, fluconizole, etc.)
Classification: monoclonal antibodies
Classification: Antifungals
Use(s): Prevention of serious lower respiratory tract disease caused by
RSV in pediatric PT’s. Use(s): fungal infections: tinea pedis (common) to sporotrichosis (rare)

Action: A humanized monoclonal antibody that exhibits neutralizing and Action:  cell wall permeability.Some interfere w/ protein synthsis by
fusion-inhibitory activity against RSV. binding to sterol..

Contraindications: Hypersensitivity, adults, and cyanotic congenital Contraindications: Hypersens., Pregnant or Lactating Pts.
heart disease.
Side Effects: Nephrotoxicity, hypokalemia, chills, fever, N/V,
Side Effects: N/V/D, URI, apnea, and rash site injection. muscle & joint pain, HA, anorexia, abd. Pain.

Nursing implications: For presence of RSV infections. Nursing implications: Monitor LFT’s, do not administer w/ antacids.

Trade Name: Cotazym


Classification: Digestant Trade Name: Pancreatin

Use(s): Exocrine pancreatic secretion insufficiency, cystic fibrosis, Classification: Digestant


steatorrhea, and pancreatic enzyme deficiency.
Use(s): Exocrine pancreatic secretion insufficiency, cystic fibrosis
Action: Pancreatic enzyme needed for breaking down substances from (digestive aid)
the pancreas.
Action: Pancreatic enzyme needed for breakdown of substances
Contraindications: Allergy to pork, chronic pancreatic disease. released from the pancreas.

Side Effects: Anorexia, N/V/D Contraindications: Hypersensitivity to pork, chronic pancreatic disease.

Nursing implications: Assess for proper development, administer with Side Effects: Anorexia, N/V/D, and rash, hypersensitivity, buccal
meals, I&O ratio, 3 p’s. soreness.

Nursing implications: Assess I&O, for 3 P’s for allergy to pork.


Trade Name: Pancrease Trade Name: Mucomyst
Classification: Mucolytic; antidote - acetaminophen
Classification: Digestant
Use(s): Bronchitis; pneumonia; CF; emphysema; diagnostic in lab
Use(s): Exocrine pancreatic secretion insufficiency, cystic fibrosis
tests.
(digestive aid), and Pancreatic enzyme deficiency.
Action: Decreases viscosity of secretions by breaking disulfide links of
Action: Pancreatic enzyme needed for breakdown of substances
mucoproteins.
released from the pancreas.
Contraindications: Hypersensitivity; increased ICP, status
Contraindications: Allergy to pork, chronic pancreatic disease.
asthmaticus.
Side Effects: N/V/D
Side Effects: Dizziness; drowsiness, nausea, vomiting,
bronchospasm, hemoptysis. stomatitis
Nursing implications: Assess for 3 P’s, pork sensitivity, appropriate
height and weight.
Nursing implications: Assess cough, respiratory status, VS.

Trade Name: Flexeril (cyclobenzaprine) Trade Name: Pulmozyme


Classification: Skeletal muscle relaxant, central acting.
Classification: cystic fibrosis agent
Use(s): Adjunct for relief of muscle spasm and pain in muscle injuries.
Use(s): Management of Cystic fibrosis
Action: Unknown may be related to antidepressant effects.
Action: Breaks down molecules of infected sputum, to help get the
sputum out.
Contraindications: Acute recovery from an MI, dysrhythmias, heart
block, CHF, hypersensitivity, child <12 years, thyroid disease.
Contraindications: Hypersensitivity
Side Effects: Dizziness, weakness, drowsiness, and dysrhythmias.
Side Effects: Possible laryngitis, uticaria, rash, chest pain.
Nursing implications: Assess blood studies, LFT’s, ECG in epileptic
Nursing implications: Assess respiratory function, B/P, pulse, lung
Pt’s., allergic Rx, CNS Depression.
sounds.
Trade Name: Cromolyn (same as intal)
Trade Name: Robaxin
Classification: Antiasthmatic
Classification: Skeletal muscle relaxant, central acting.
Use(s): Preventive allergic rhinitis, asthma, and bronchial asthma,
exercise induced asthma. Use(s): Adjunct for relief of spasms and pain in muscles, tetanus
management.
Action: Stabilizes the membrane of the senthestized cell, preventing the
release of additional chemical mediators Action: Depresses multisynaptic pathways in the spinal cord, causing
skeletal muscle relaxant.
Contraindications: Hypersensitivity to this drug or lactose or status
asthmaticus. Contraindications: hypersensitivity, child <12 yr., intermittent
porphyria
Side Effects: Headache, dizziness, urinary frequency, dysuria, N/V, dry
mouth, bitter taste. Side Effects: Dizziness, weakness, drowsiness, seizures, N/V,
anaphylaxis.
Nursing implications: Assess eosinophil count during treatment,
respiratory status. Nursing implications: Assess blood studies, liver function tests,
ECG, allergic RX, CNS depression.

Trade Name: Prednisone


Trade Name: Valium (diazepam)
Classification: Corticosteroid
Classification: Antianxiety, anti-convulsant, skeletal muscle relaxant
Use(s): Severe inflammation, immunosuppression, neoplasm’s, MS,
collagen disorders. Use(s): Anxiety, acute ETOH withdrawal, adjunct in seizure
disorders. IV with anesthesia for labor
Action: Decreases inflammation by suppression of migration of
leukocytes and fibroblasts increases capillary permeability and lysosomal Action: Potentates the action of GABA, especially in the limbic
stabilization. system.

Contraindications: Psychosis, hypersensitivity, amebiasis, fungal Contraindications: Hypersensitivity to benzodiazepines, narrow


infections, child <2 years old, aids, TB. angle glaucoma, psychosis.

Side Effects: Circulatory collapse, thrombophlebitis, embolism, GI Side Effects: Neutropenia, respiratory depression, dizziness
hemorrhage. drowsiness, and orthostatic hypotension.

Nursing implications: Assess for N/V, Weight, BP, I&O, infection, Nursing implications: Assess B/P, anxiety, for seizure, for
edema, mental status. changes in mental status.
Trade Name: Indocin Trade Name: Tilade
Classification: NSAID Classification: Antiasthmatic

Use(s): Rheumatoid arthritis, gout, closure of patent ductus arteriosus in Use(s): Severe perennial bronchial asthma, prevention of exercise-
premature infants. induced asthma. Not for treatment of acute asthma attacks.

Action: Inhibits prostaglandin synthesis, analgesic, anti-inflammatory, Action: Stabilizes the membrane of the sensitized mast cell,
antipyretic. preventing further release of chemical mediators after the initial
response.
Contraindications: Hypersensitivity, asthma, severe renal disease,
severe renal disease, and severe hepatic disease Contraindications: Hypersensitivity to this drug or lactose, status
asthmaticus.
Side Effects: N/V/D, ulceration, and perforation, GI bleeds, hematuria,
Oliguria. Side Effects: Throat irritation, cough, nasal congestion, and rhinitis,
burning eyes, N/V, bitter taste.
Nursing implications: Assess renal, blood and liver status, eye and
ear problems, for confusion. Nursing implications: Assess pulmonary function test, respiratory
status

Trade Name: Aspirin ( acetylsalicylic acid ASA)


Trade Name: Intal
Classification: Non-narcotic analgesic, nonsteroidal anti-inflammatory,
Classification: Antiasthmatic antipyretic, antiplatelet

Use(s): Allergic rhinitis, severe perennial asthma, prevention of exercise Use(s): Mild to moderate pain or fever, prophylaxis of MI, angina &
induced bronchial asthma, asthma induced by pollutants. ischemic stroke

Action: Stabilizes the membrane of the sensitized mast cell, preventing Action: Blocks pain impulses at the CNS, antipyretic, decreases
further release of chemical mediators. platelet aggregation, prolongs bleeding

Contraindications: hypersensitivity to this drug or lactose, status Contraindications: Hypersensitivity to ASA, yellow #5, GI bleed,
asthmaticus Children <12 years old, children with flu-like symptoms, peptic ulcer.

Side Effects: Headache, dizziness, neuritis, urinary frequency, dysuria, Side Effects: convulsion, GI bleed, hepatitis, and Reye’s syndrome,
nausea, vomiting. decreases hearing acuity, gastric irritation

Nursing implications: Assess eosinophil, respiratory status. Nursing implications: Assess Liver function, renal function, blood
studies, I&O ratio. Do not give with Ibuprofen, take with food
Trade Name: Solu-Cortef
Trade Name: Alupent
Classification: Corticosteroid
Classification: Bronchodilator selective B2 agonist
Use(s): Severe inflammation, septic shock, adrenal insufficiency,
Use(s): Bronchial asthma, bronchial spasm. ulcerative colitis, collagen disorders.

Action: Relaxes bronchial smooth muscle by direct action on B 2 Action: Decreases inflammation by suppression of leukocytes
Adrenergic receptors. reverses capillary permeability.

Contraindications: Hypersensitivity to sympathomimetics, narrow Contraindications: Psychosis, hypersensitivity, idiopathic


angle glaucoma. thrombocytopenia, fungal infections, bronchial disease, children
<2 years old, aids, TB.
Side Effects: N/V, palpitations, tachycardia, tremors, nausea,
nervousness, headache, and increased bronchospasm, cardiac arrest. Side Effects: Circulatory collapse, thrombophlebitis, and embolism,
thrombocytopenia, GI hemorrhage.
Nursing implications: Assess respiratory function, for tolerance.
Nursing implications: Assess mental status, weight, B/P, I&O,
infection, edema, hypertension.

Trade Name: Theophylline Trade Name: Proventil/Ventolin


Classification: Adrenergic B2-agonist, sympathomimetic,
Classification: Spasmolytic, bronchodilator
bronchodilator
Use(s): Bronchial asthma, broncho-spasm of COPD, chronic bronchitis.
Use(s): Prevention of exercise induced asthma, bronchospasm,
bronchitis, emphysema, or other respiratory diseases.
Action: Relaxes bronchial smooth muscle by blocking
phosphodiesterase.
Action: Causes bronchodilation by interacting with B2 receptors,
relaxes bronchial smooth muscle.
Contraindications: Hypersensitivity to xanthine, tachydysrhythmias.
Contraindications: Hypersensitivity to sympathomimetics,
Side Effects: Convulsions, palpitations, tachycardia, tremors, nausea,
tachydysrhythmias, severe cardiac disease, and heart block.
nervousness, and headache,restlessness, irritability, insomnia, dizziness.
Adverse CNS reactions often more severe in children
Side Effects: Palpitations, tachycardia, tremors, nausea,
nervousness, headache, and increased bronchospasm.
Nursing implications: Assess Theophylline level, heart rate,
respiratory status, for allergic reactions, monitor blood levels. If dose
Nursing implications: Assess the need for the drug, respiratory
missed call MD before doubling.
function, ability to self medicate, evidence of allergic Reactions
Trade Name: Accutane (isotretirion)
Trade Name: Brethine (terbutaline)
Classification: Antiacne agent
Classification: Selective B2 agonist; Bronchodilator
Use(s): Rarely used for severe recalcitrant acne
Use(s): Bronchospasm, hyperkalemia, and premature labor.
Action: Unknown
Action: Relaxes bronchial smooth muscle by acting on B2 Adrenergic
Contraindications: hypersensitivity, inflamed skin, pregnancy receptors that relax bronchial smooth muscle.
Side Effects: Pseudotumor cerebri, hyperostosis, hepatotoxicity, chelitis, Contraindications: Hypersensitivity to sympathomimetics, narrow
dry skin, skin fragility, pruritus, dry mouth, depression. Fetal angle glaucoma, tachydysrhythmias.
abnormalities
Side Effects: N/V, palpitations, tachycardia, tremors, nausea,
Nursing implications: caution if psychiatric disorder. nervousness, headache, and cardiac arrest.

Nursing implications: Assess respiratory function, vitals, and


tolerance to treatment, monitor FHT’s, uterine activity

Trade Name: Azulfidine (sulfasalazine) Trade Name: Aminophylline


Classification: Anti-inflammatory Classification: Spasmolytic

Use(s): Ulcerative colitis, used for rheumatoid arthritis in pt’s who are Use(s): Bronchial asthma, bronchial spasm, Cheyne-Stokes
unresponsive to or intolerant to NSAIDS. respiration. wheezing

Action: anti-inflammatory in connective tissue. A prodrug that delivers Action: Relaxes bronchial smooth muscle, and produces
sulfapyridine and 5-aminosalicylic acid to the colon. bronchodilation.

Contraindications: Hypersensitivity to sulfonamides or salicylates, Contraindications: Hypersensitivity to xanthines,


pregnancy @ term, child <2 years old, intestinal/urinary obstruction. tachydysrhythmias

Side Effects: Anaphylaxis, N/V/D, abdominal pain, hepatitis, Side Effects: N/V, palpitations, tachycardia, tremors, nausea,
convulsions, skin and urine discoloration may occur nervousness, headache, tachypnea.

Nursing implications: Assess kidney function studies, for blood Nursing implications: Assess: Theophylline levels, respiratory
dyscrasis, allergic reaction. Administer after meals status, allergic reactions.
Trade Name: Kwell (lindane)
Trade Name: Nix (permethrin)
Classification: Antiparasitic-Pediculicide Classification: Scabicide, pediculicide.

Use(s): Lice, ticks, nits, flea nits Use(s): Scabies, Lice, nits.

Action: disrupts parasitic nerve cells. Action: Stimulates the nervous system of arthropods, causing
seizures and death of organism.
Contraindications: Hypersensitivity,
Contraindications: Hypersensitivity; premature neonate; pt’s with
Side Effects: Burning, pruritus, erythema, numbness, tingling. seizure disorders, inflammation of skin, or breaks in skin.

Nursing implications: Assess for signs of infection. Identify sources Side Effects: Pruritis, rash, irritation, contact dermatitis, aplastic
of infection. anemia, seizures

Nursing implications: Assess for organisms prior to/after


treatment. Identify sources of infection.

Trade Name: Norplant Trade Name: Urecholine (bethanechol)


Classification: Cholinergic stimulant.
Classification: Contraceptive system
Use(s): Urinary retention (postoperative, postpartum); neurogenic
Use(s): Prevention of pregnancy for 5 years.
atony of the bladder with retention.
Action: Progestin that inhibits secretion of gonadotropins & prohibits
Action: Stimulates the muscarinc Ach receptors directly; mimics
follicular maturation.
parasympathetic NS stimulation, stimulates GI motility/Micturition.
Contraindications: , pregnancy, and liver disease/tumors, breast
Contraindications: Hypersensitivity, severe Bradycardia, asthma,
carcinoma.
hypotension, PUD, CAD, COPD.
Side Effects: dizziness, HA, nervousness, vaginitis.
Side Effects: Rash, N/V/Bloody diarrhea, Cardiac arrest, circulatory
collapse, acute asthma, dyspnea, bronchoconstriction.
Nursing implications: Assess for jaundice, acne, and menstrual
irregularities.
Nursing implications: Assess vitals, I&O, Assess for abnormal
HR/Rhythm and respiratory issues D/C if develop. Give on an empty
stomach
Trade Name(s) Xylocaine
Classification: Anesthetics local Trade Name: Danocrine (danazol)

Use(s): Nerve block for pain Classification: androgen

Action: Inhibits conduction of nerve impulses from sensory Use(s): endometriosis, fibrocystic breast disease, and prevention of
Nerves. heredity angioedema.

Contraindications: Hypersensitivity, application to large areas Action: Decreases FSH, LH which leads to amenorrhea / anovulation.

Side Effects: Rash, irritation, and sensitization Contraindications: Severe renal/cardiac/hepatic disease, , pregnancy.

Nursing implications: Assess pain, assess for any infection, Side Effects: Rash, acne, dizziness, mood change, cramps, BP
evaluate response, redness, swelling, pain.
Nursing implications: Assess K+, mental status, hypercalcemia,
I&O.

Trade Name(s) Duramorph Trade Name(s) Novocain


Classification: Local anesthetic
Classification: Anesthetics: Opiate analgesic
Use(s): Spinal, epidermal, periph. nerve block, & perineum,
Use(s): Severe pain
lower extremities, infiltration.
Action:Depresses pain impulse transmission at the spinal cord level by
Action: Completes w/ Ca+ for sites in nerve membrane that
interacting with opioid receptors.
controls Na+ transport across the cell membrane;
Contraindications: hypersensitivity, addiction, hemorrhage,
decreases rise of depolarization phase of action
bronchial asthma, increased intracranial pressure.
potential.
Side Effects: Drowsiness, dizziness, confusion, headache,
Contraindications: Hypersens., children 12, severe liver disease.
sedation, euphoria, palpitations, bradycardia, change in B/P, n/v,
Side Effects: Palpatations, tachycardia, tremors, nausea,
rash, respiratory depression.
nervousness, & HA.
Nursing implications: Assess:
Nursing implications:
Pain
Assess: VS, HFT if used during labor, allergic reactions, rash
Bowel status
urticaria, itching, as well as cardiac status.
I&O
Administer: Only clear drugs, only with resuscitative equipment
Vitals
nearby, only use drugs w/o preservatives for epidural
CNS
or caudal anesthesia.
Respiratory depression
Allergic reactions
Trade Name(s) Marcaine
Trade Name(s) Nesacaine
Classification: Local anesthetic
Classification: Local anesthetic
Use(s): Epidural, peripheral block, caudal anesthesia, &
Use(s): Epidural, peripheral block, caudal anesthesia, & Infiltration, block
infiltration block.
Action: Block nerve impulses at the point of contact in all kinds
Action: Competes with calcium for sites in the nerve membrane of nerves.
that control sodium transport. Thus slowing the
depolarization phase of the action potential. Contraindications: Hypersensitivity.

Contraindications: Hypersensitivity, children <12 years, severe Side Effects: Anxiety, dizziness, HA, restlessness, tremor, HTN
liver disease. palpitations, tachycardia, anginal pain.

Side Effects: Seizures, loss of consciousness, myocardial Nursing implications: Monitor for cyanosis, angina
depression, arrest, dysrhythmias, status asthmaticus,
respiratory arrest, anaphylaxis.
Nursing implications: VS,  FHT’s. Look for allergic reactions.

Trade Name(s) Demerol (meperidine hydrochloride)


Trade Name: Vitamin K (aqua mephyton) Classification: Opiate analgesic. Narcotic analgesic

Classification: Vitamin K, Fat-soluble vitamin Use(s): Pain control

Use(s): Vitamin K malabsorption, to prevent hemorrhage, prevents Action: Depresses pain impulse transmission at the spinal cord
hemorrhagic disease level by interacting with opioid receptors.

Action: Needed for adequate blood clotting, factors 2, 7, 9, 10 Contraindications:: Hypersensitivity, addiction.

Contraindications: Hypersensitivity, severe hepatic disease, last few Side Effects: Increased ICP, seizures, respiratory depression,
weeks of pregnancy. drowsiness, dizziness, confusion, headache, sedation, &
euphoria
Side Effects: HA, brain damage, hemolytic anemia, hemoglobinuria
& hyperbilirubinemia. Nursing implications: Assess pain, renal function, I&O,
constipation, allergic reaction, respiratory rate, in labor do not
Nursing implications: Assess for bleeding (emesis, stools, urine) Check give if delivery is expected within 2-4 hours
PTT, nutritional status (is K intake adequate?)
Trade Name(s): Stadol (butorphanol)
Trade Name(s): Nubain
Classification: Narcotic analgesic, opiate analgesic
Classification: Opioid analgesic
Use(s): Moderate to severe pain.
Use(s): Moderate to severe pain
Action: Decreases pain impulse at the spinal cord level by
interacting with opioid receptors. Action: Depresses pain impulse transmission at the spinal cord
level by interacting with opioid receptors.
Contraindications: Hypersensitivity, addiction, CHF, myocardial
infarction Contraindications: Hypersensitivity and addiction.

Side Effects: Drowsiness, dizziness, headache, confusion, sedation, Side Effects: Drowsiness, dizziness, confusion, HA, sedation,
euphoria, n/v, anorexia, constipation, cramps. Respiratory depression, euphoria, N/V, anorexia, constipation, and cramps.
pulmonary HTN.
Nursing implications: I&O, CNS changes, dizziness, need for
Nursing implications: Assess pain, decreased output, CNS changes, medication, allergic reactions.
allergic Rx and respiratory dysfunction.

Trade Name(s): Narcan (naloxone)


Trade Name: Morphine Sulfate
Classification: Opioid antagonist
Classification: Opiate analgesic
Use(s): Reverses narcotics, treat respiratory depression caused by
Use(s): Severe pain
narcotics and narcotic overdose
Action: Depress pain impulse transmission at the spinal cord level by
Action: Competes with opioids at opiate receptor sites.
interacting with opioid receptors
Contraindications: Hypersensitivity
Contraindications: Hypersensitivity, addiction, hemorrhage, bronchial
asthma, increase ICP.
Side Effects: Drowsiness, nervousness, Rapid pulse, V-Tach,
V-Fib.
Side Effects:
Nursing implications: Withdrawal symptoms, respiratory & cardiac
Nursing implications: Assess need for pain medication, respiratory
status, pain.
depression, and allergic reactions. Antidote is Narcan
Trade Name: Versed (midazolam) Trade Name: Sublimaze
Classification: Sedative, hypnotic Classification: Narcotic analgesic

Use(s): Pre-op, general induction, sedation for procedures. Use(s): Pre-op, post-op, adjunct to general anesthetic

Action: Binds to Benzodiazepine receptors, induces amnesia Action: Inhibits ascending pain pathways

Contraindications: Hypersensitivity, shock, coma, Etoh ingestion, acute Contraindications: Hypersensitivity to opiates, myasthenia gravis
narrow angle glaucoma.
Side Effects: Bradycardia, arrest, respiratory depression, respiratory
Side Effects: Apnea, laryngospasm, bronchospasm, retrograde amnesia arrest.

Nursing implications: injection site, vital signs, and signs of apnea Nursing implications: Vital signs

Trade Name: Erythromycin ophthalmic ointment


Trade Name: Achromycin ophthalmic ointment
Classification: Antibacterial
Classification: Antibacterial
Use(s): prevention of gonococal conjunctivitis and chiamydial
conjunctivitis Use(s): prevents neisseria gonorrhea, ophthalmic neonatorium
Action bacteriostatic or bacteriocidal based on concentration and target Action bacteriostatic
organism
Contraindications: none
Contraindications: none
Side Effects: chemical conjunctivitis
Side Effects: chemical conjunctivitis
Nursing implications: place ½ in. ribbon of ointment in the lower
Nursing implications: place ½ in. ribbon of ointment in the lower conjunctival sac within 1 hour of delivery
conjunctival sac within 1 hour of delivery
Trade Name: Toradol (ketorolac)

Trade Name: Hepatitis B Vaccine Classification: Nonsteroidal anti-inflammatory/nonopioid analgesic.

Classification: Immune Globulin Use(s): Mild to moderate pain.

Use(s): Prevention of Hepatitis B virus in exposed patients Action: Inhibits prostaglandin synthesis, analgesic, anti-inflammatory

Action: Provides passive immunity to Hepatitis B Contraindications: Hypersensitivity, asthma, renal disease, PUD,
lactation, CV bleed.
Contraindications: Hypersensitivity to immune globulins, coagulation
disorders Side Effects: Gi Bleeds, perforation, Dysuria, Hematuria

Side Effects: Soreness at injection site, angioedema, anaphylaxis Nursing implications: For ASA sensitivity, pain characteristics,
bleeding time, tinnitus.
Nursing implications: For history of anaphylaxis to vaccines.

Trade Name: chlorpropamide (Glucamide)


Trade/Generic Name: Motrin/Advil/Ibuprofen
100-750mg/day
Classification: Oral Hypoglycemic Agents-1st Generation Sulfonureas
Classificationn: NSAID
Use(s): Hyperglycemia, Adjunct to diet, exercise to  glucose levels
Use(s): Fever, dental pain, rheumatoid arthritis, musculoskeletal
w/ Mild to mod.Type 2 DM.
disorders
Action: Unk., probably stimulates insulin release from the pancreas.
Action: Inhibits prostaglandin synthesis, analgesic, and anti-
 peripheral sensitivity to insulin. Potentiates ADH.
inflammatory, antipyretic.
Contraindications: Hypersensitivity to sulfonylureas, juvenile or
Contraindications: PUD, asthma, and severe renal/hepatic disease.
brittle diabetes, pregnancy, lactation, pregnancy.
Side Effects: N/V/D, dizziness, light-headedness, fatigue
Side Effects: parasthesia, fatigue, dizziness, vertigo, malaise, HA,
tinnitus, N/V, heartburn, epigastric distress, rash, urticaria.
Nursing implications: For pain, fever/temp, and for a history of
contraindications.
Nursing implications: caution w/ renal failure, elderly,
malnourished, allergy to. Monitor S/S of hypoglycemia.
Trade Name: tolbutamide (Orinase) Trade Name: acetohexamide (Dymelor)
100-1,000mg/day
Classification: Oral Hypoglycemic Agents-1st Generation Sulfonureas Classification: Oral Hypoglycemic Agents-1st Generation Sulfonureas

Use(s): Hyperglycemia, Adjunct to diet, exercise to  glucose levels w/ Use(s): Hyperglycemia, Adjunct to diet, exercise to  glucose levels
Mild to mod.Type 2 DM. w/ Mild to mod.Type 2 DM.

Action: Unk., probably stimulates insulin release from the pancreas.  Action: Unk., probably stimulates insulin release from the pancreas.
peripheral sensitivity to insulin.  peripheral sensitivity to insulin. Potentiates ADH.

Contraindications: Hypersens., sole agent for Type 1, pregnant or Contraindications: Hypersensitivity to sulfonylureas, juvenile or
lactating, DKA. brittle diabetes, pregnancy, lactation.

Side Effects: Hypoglycemia, N/V, cholestasis, rash, pruritis, Side Effects: Hypoglycemia, N/V, cholestasis, rash, pruritis,
leukopenia, thrombocytopenia. leukopenia, thrombocytopenia.

Nursing implications: caution w/ renal failure, elderly, malnourished, Nursing implications: caution w/ renal failure, elderly,
allergy to. Monitor S/S of hypoglycemia. malnourished, allergy to. Monitor S/S of hypoglycemia.

Trade Name: tolazamide (Tolinase)


Trade Name: glipizide (Glucatrol)
Classification: Oral Hypoglycemic Agents-1st Generation Sulfonureas
Classification: Oral Hypoglycemic Agents-2nd Generation Sulfonureas
Use(s): Hyperglycemia, Adjunct to diet, exercise to  glucose levels w/
Use(s): Stable adult onset DM type II, NIDDM.
Mild to mod.Type 2 DM.
Action: Causes functioning pancreas cells to release insulin.
Action: Unk., probably stimulates insulin release from the pancreas. 
peripheral sensitivity to insulin. Potentiates ADH.
Contraindications: Hypersensitivity to sulfonylureas, juvenile or
brittle Diabetes.
Contraindications: Hypersensitivity to sulfonylureas, juvenile or brittle
diabetes, pregnancy, lactation, pregnancy
Side Effects: N/V/D, headache, dizziness, hepatotoxicity,
leukopenia, hemolytic anemia.
Side Effects: Hypoglycemia, N/V, cholestasis, rash, pruritis,
leukopenia, thrombocytopenia.
Nursing implications: Assess for hypo/hyperglycemic reactions
that can occur soon after a meal. Assess blood and urine glucose
Nursing implications: caution w/ renal failure, elderly, malnourished,
levels after treatment.
allergy to. Monitor S/S of hypoglycemia.
Trade Name: glyburide (Diabeta,Micronase) Trade Name: Pioglitazone hydrochloride (NDH) (Actos)
Classification: Oral Hypoglycemic Agents-NEW
Classification: Oral Hypoglycemic Agents-2nd Generation Sulfonureas
Use(s): Stable adult onset DM
Use(s): Stable adult onset DM (NIDDM)
Action:  insulin sensitivity by hepatic glucose metabolism
Action: Causes functioning Beta cells in the pancreas to release insulin.
Contraindications: Hypersensitivity to Thiazolidinedione, lactation,
Contraindications: Hypersensitivity to sulfonylureas, juvenile or brittle
children, DKA,
Diabetes
Side Effects: Hypoglycemia, aggravated DM, URTI, Pharyngitis, HA,
Side Effects: Headache, weakness, N/V/D, Rash, Hypoglycemia
edema,  HDL.
Nursing implications: Assess for hypo/hyperglycemic reaction that
Nursing implications: Assess for Hypo/hyperglycemic reactions,
can occur after meals.
Monitor CBG’s, LFT’s, CBC. Caution w/ CHF.

Trade Name: metformin (Glucophage) Trade Name:


insulin: Lispro / Lente / Regular/
Semilente/ NPH / Ultralente /70-30
Classification: Oral Hypoglycemic Agents-Biguanides Classification: Insulins
Use(s): DM type I ,ketoacidosis in DM type I & II, PTs. on TPN or G
Use(s): Stable adult onset diabetes mellitus (NIDDM) tube feeding. See pharm book for peak, onset and duration times

Action: Inhibits hepatic glucose production and increases sensitivity of Action:  blood sugar by facilitating the uptake & metabolism if
insulin dependent cells. glucose by insulin dependent cells. Also inhibits hepatic glucose
production & the breakdown of glycogen, protein & fat, while it
Contraindications: Hypersensitivity, hepatic, renal disease, alcoholism, promotes the formation of glycogen, protein & triglycerides.
cardiopulmonary disease, history of lactic acidosis.
Contraindications: Hypersensitive to protamine, Hypoglycemia,
Side Effects: N/V/D, rash, headache, weakness, dizziness. NPO status,

Nursing implications: Assess for hypo/hyperglycemic reaction, assess Side Effects: Hypoglycemia, anaphylaxis, hepatotoxicity.
CBC, for lactic acidosis. Nursing implications:  CBG’s (fasting & during treatment),
rotate injection sites, Monitor signs of hypoglycemia. Peak times as per
pharm book, Regular insulin acts quickly. Humalog acts quicker than
regular. Regular can be administered IV and/or SQ
Trade Name: rosiglitazone maleate (NDH) (Avandia) Trade Name: Estrogen/Progesterone (comb.)

Classification: Contraceptives
Classification: Oral Hypoglycemic Agents-NEW
Use(s): Birth Control.
Use(s): Stable adult onset DM, NIDDM.
Action:  the release of FSH & LH.
Action: Improves insulin resistance by hepatic glucose metabolism.
Contraindications: Pregnancy, thrombophlebitis, thromboembolic
Contraindications: Hypersensitivity to Thiazolidinediones
disorders, estrogen dependent CA of the breast or reproductive organs.
Side Effects: Hypo/hyperglycemia, fatigue, Headache
Side Effects: Fluid retention, N/V, cramping, constipation,
hyperpigmentation, HTN,  risk of MI,
Nursing implications: Assess for hypo/hyperglycemic reactions,
blood studies
Nursing implications: Monitor for adverse reactions.

Trade Name: glucagon Trade Name: Progesterone only


Classification: Oral hyperglycemic agent (occurs naturally in body also)
Classification: Progesterone
Use(s): Sever hypoglycemia, insulin antagonist
Use(s): Contraception, amenorrhea, PMS, abnormal uterine bleeding.
Action: Converts hepatic glycogen to glucose.
Action: Inhibits secretion of pituitary gonadotropins, which prevents
follicular maturation.
Contraindications: hypoglycemia,
Contraindications: Breast CA, pregnancy, thrombolytic disorders.
Side Effects: Hypersens., Pt. W/ pheochromocytoma, hyperglycemia,
hypotension, N/V, urticaria, resp. distress.
Side Effects: Dizziness, HA, migraine, fatigue, depression, stroke,
embolism, MI, spontaneous Abortion
Nursing implications: Monitor CBG’s, VS, S/S of hyperglycemia. Initial
dose is IM effect in 5-20 minutes. IV for severe hypoglycemia.
Nursing implications: Assess Weight, B/P, I&O, edema, HTN.
Destroyed by the GI tract.
Trade Name: Depo-Provera Trade Name: Ergotrate Maleate

Classification: Antineoplastic, hormone Classification: Oxytocic

Use(s): Uterine bleeding, endometrial / renal cancer, and secondary Use(s): Postpartum or postabortion hemorrhage
amenorrhea
Action: Stimulates uterine contractions and vascular smooth muscle,
Action: Inhibits secretion of pituitary gonadotropins, which prevents decreases bleeding.
maturation and ovulation.
Contraindications: Hypersensitivity to ergot medications, augmentation
Contraindications: Breast/reproductive CA, , pregnancy, thrombolytic of labor, before delivery of placenta, threatened AB
disorders.
Side Effects: Headache, dizziness, fainting, HTN, Chest pain, N/V
Side Effects: Stroke, PE, MI, N/V, spontaneous AB.
Nursing implications: Assess for ergotism, vitals, and fundal tone.
Nursing implications: Assess Weight, B/P, I&O, edema, HTN.

Trade Name: RU486 (mifepristone) Trade Name: Nupercainal Ointment

Classification: Contraceptives Classification: Topical anesthetics


Dose: 600 mg PO
Use(s): Early Pregnancy Termination Use(s): Minor external irritation

Action: Inhibits progesterone receptors. Action: Inhibits the conduction of nerve impulses from sensory nerves

Contraindications: Hypersensitivity, ectopic preg., IUD use, Contraindications: Hypersensitivity, large areas, Less than 1 year old.
anticoagulants, cortico-steriods, chronic adrenal failure, bleeding
disorder. Side Effects: Rash, irritation, and sensitization

Side Effects: Incomplete abortion, hemorrhage fetal malformation, Nursing implications: Assess pain, do not use until infection is
vag. Bleeding, abd cramps, abd pain, N/V, HA, treated, remove any scales or crust before applying medication

Nursing implications: Monitor for adverse reactions.


Trade/generic: Methergine (methylergonovine maleate)
Trade Name: Epifoam
Class: Oxytocic, Uterine Motility Agent: Ergot Alkaloid
Classification: Topical Glucocorticoids
Ind: Treatment of PPH or postabortion,  uterine contractions, uterine
atont Use(s): Contact dermatitis

Route: PO, IM, PR Action: Antipruritic, anti-inflammatory


Action: Stimulates uterine, vascular, smooth muscle, causing
contractions &  bleeding Contraindications: Hypersensitivity, viral and fungal infections.

Contra: Hypersensitivity to ergot preparations, in labor, Side Effects: Acne, atrophy, epidermal thinning, purpura, and striae.
before delivery of placenta, hypertension, PID,.
Nursing implications: Assess for a temperature, and for systemic
S/E: N/V, HA, dizziness, dyspnea, cramping, chest pain, absorption leading to a temperature.
hypertension & dysrhythmias

RN: monitor vitals, character & amt. of vag.bdg & watch


for hemorrhage.

Trade Name: Syntocinon Nasal Spray


Trade Name: Colace
Classification: Oxytocic
Classification: Laxative, emollient
Use(s): Stimulation or induction of labor; missed or incomplete
abortion; postpartum bleeding. Use(s): To soften stools

Action: Acts directly on myofibrils, producing uterine contractions; Action: Increases water and fat penetration in the intestine; allows for
stimulates milk ejection by the breast. easier passage of the stool

Contraindications: Hypersensitivity, serum toxicity, fetal distress, and Contraindications: Hypersensitivity, obstruction, fecal impaction, and
hypertonic uterus. nausea/vomiting.

Side Effects: convulsions, tetanic contractions. Hypo/Hyper-tension, Side Effects: Nausea, cramps, diarrhea, rash, bitter taste, throat
Brady/tachy-cardia, abruptio placenta, decreased uterine blood flow. irritation.

Nursing implications: I&O, respiration, B/P and pulse (watch for Nursing implications: Causes of constipation, bleeding, N/V
hemorrhage) Length of contractions.
Trade Name: Proctofoam Trade Name: Surfak
Classification: Topical anesthetics
Classification: Laxative, emollient
Use(s): Rectal pain and itching, post partum hemorrhoids
Use(s): To soften stools
Action: Inhibits conduction of nerve impulses
Action: Increases water and fat penetration in the intestine; allows for
easier passage of the stool
Contraindications: Hypersensitivity, infants less than 1 year of age.
Contraindications: Hypersensitivity, obstruction, fecal impaction, and
Side Effects: Rash, irritation, and sensitization.
nausea/vomiting.
Nursing implications: Assess for pain and infection.
Side Effects: Nausea, cramps, diarrhea, rash, bitter taste, throat
irritation.

Nursing implications: Causes of constipation, bleeding, N/V.

Trade Name: Zantac


Trade Name: Rubella Vaccine
Classification: H2-histamine receptor antagonist
Classification: Vaccines & toxoids
Use(s): Duodenal ulcer, H. Pylori, ERD
Use(s): Rubella immunization
Action: Inhibits histamine sites, which ceases acid production
Action: Promotes immunity by causing antibodies to be produced.
Contraindications: Hypersensitivity
Contraindications: immunosuppressed, CA, blood dyscrasia, GG
Side Effects: HA, Sleeplessness, confusion, hepatotoxicity. disorders, TB, do not get pregnant for 3 months

Nursing implications: I&O, Bun, Creatine, mental status, GI Side Effects: HA, malaise, rash, pain, erythema, sore throat,
complaints.
Nursing implications: Watch for anaphylaxis. Give SQ
Trade Name(s): Yutopar ( ritodrine)
Trade Name: Dulcolax
Class: Tocolytic, uterine relaxant.
Classification: Laxative, stimulant
Ind: Management of premature labor.
Use(s): Short term treatment of constipation, bowel or rectal
preparation for surgery/examination Route: PO, IV

Action: Acts directly on the intestines by increasing motor activity Action:  frequency & intensity of uterine contractions
by stimulating beta-2 receptors in uterine smooth muscle.
Contraindications: Hypersensitivity, rectal problems, N/V, acute
abdomen, obstruction Contra: hypersens, eclampsia, HTN, dysrhythmias, before
20th week of pregnancy, bronchial asthma.
Side Effects: muscle weakness, N/V, cramps
S/E: Erythema, rash, dyspnea, hyperventilation, glycosuria,
Nursing implications: Assess cause of constipation, monitor lactic acidosis, hyperglycemia, Hypokalemia, nervousness,
blood/urine/electrolytes if used often by the patient. Assess for tremors.
cramping or rectal bleeding.
RN: Maternal & FHT, EKG, intensity & length of contractions, fluid
intake.

Trade/generic: Pitocin (oxytocin) Syntocinon


Trade Name: RhoGAM
Class: Oxytocic
Classification: Immunizing agent
Route: IM, IV, spray
Use(s): Prevention of isoimmunization in Rh negative women who are
Ind: Stimulates or induces labor; for missed or incomplete
given Rh positive blood after abortions, miscarriages, and amniocentesis
Abortion, PPH, preeclampsia, eclampsia, PROM.
Suppress active antibiody response and formation of anti-Rh(D) in Rh
negative clients exposed to Rh positive blood, promotes destruction of Rh
Action: Acts directly on myofibrils, producing uterine
positive fetal cells
contractions; stimulates milk ejection by the breast.
Action: Suppress the immune response of non-sensitized Rh cells, to
Contra: Hypers., serum toxemia, fetal distress, hypert. uterus,
sensitized cells, , blocks maternal antibody prodction
PPH, GI disturbance, diapheresis, HA, dizziness.
Contraindications: Previous immunization with the drug
S/E: Convulsions, tetanic contractions, abruptio placenta,
 uterine blood flow
Side Effects: Irritation at injection site, fever, lethargy, myalgia
RN: I&O, VS, FHT’s
Nursing implications: For allergic reactions,
Trade Name: MMR vaccine
Trade Name(s): Magnesium Sulfate
Classification: vaccine
Classification: Electrolyte, anticonvulsant
Use(s): prevention of measles, mumps, and rubella
Use(s): Smooth muscle relaxant, inhibit or prevent pre-term labor ,uterine
hyperstimulation, anticonvulsant
Action: produces antibodies to measles, mumps and rubella
Action:
Contraindications: Hypersensitivity, anemia, active infection, allergy to
Contraindications: eggs/chickens, pregnancy, febrile illness.

Side Effects: Muscle weakness, flushing, sweating, confusion, Side Effects: anaphylaxis, subacute sclerosing panencephalitis, and
sedation, depressed reflexes, flaccidity, paralysis, blindness associated with optic neuritis
hypothermia, nausea, vomiting, cramps, hypotension,
heart block, circulatory collapse. Nursing implications: Watch for skin reactions and anaphylaxis,
bronchospasm, inability to breathe, must dilute with specific diluent that
Nursing implications: Assess for magnesium toxicity, cramping, comes with the medication. Instruct female patients not to get pregnant
bleeding. In PIH prevents seizures. Calcium gluconate is the antagonist. for 3 months

Trade Name(s): Prostaglandin


Classification: hormone
Gen./Trade Name: Vitamins A, D, E, K
Use(s): To maintain patent ductus arteriosus Classification: fat soluble

Action: Relaxes the smooth muscle of the ductus arteriosus; Use(s): A-night blindness, D-maintains Ca & P homeostasis, E-antioxidant 
this results in increased o2 content in the body platelet aggregation, K-clotting factors.

Contraindications: hypersensitivity, respiratory distress Action: Catalysts for biochemical and metabolic reactions.
syndrome.
Contraindications:
Side Effects: Sepsis, peritonitis, apnea, bradycardia, wheezing,
respiratory depression, DIC, cerebral bleed, Side Effects: Anaphylaxis, N/V, fatigue, weakness, HA. dizziness, lethargy.
dysrhythmias
Nursing implications: monitor bilirubin, hypersensitivity, bleeding, PT times.
Nursing implications: ABG’s, apnea, bradycardia
Trade Name: Iron
Trade Name: DPT vaccine
Classification: Vitamin
Classification: Vaccine, toxoid
Use(s): To prevent maternal deficiency.
Use(s): Prevention of diphtheria, tetanus, and pertussis.
Action: Replaces iron stores needed for RBC development
Action: Provides immunity by stimulating antibody/antitoxin production.
Contraindications:
Contraindications: Hypersensitivity, active infection,
immunosuppression, and febrile illness
Side Effects: N/V/D, constipation, black or red tarry stools, epigastric
pain.
Side Effects: seizures, N/V, anaphylaxis, encephalopathy
Nursing implications: Liquid forms should be diluted to prevent
Nursing implications: for skin reactions, inability to breath,
discoloration of teeth.
bronchospasm.

Gen./Trade Name: bile salts (Bilron)


Trade Name: Reglan
Classification: Digestive agents
Classification: cholinergic
Use(s): Initiate bile flow from the liver. Once used to treat pts. w/
biliary fistula & resection of the ileum. Used infrequently today. Use(s): prevention of nausea and vomiting.
Action: Bile salts are converted to cholic acid & chenodeoxycholic acid. Action: blocks dopamine in the chemoreceptor trigger zone
They conjugate w/ glycerine & taurine to form bile acids. Then the salts of
the bile acids are secreted in the bile. Contraindications: Hypersensitivity to this drug or procainamide,
seizure disorders, breast cancer
Contraindications: Hepatic dysfunction, obstruction, N/V, abd. pain.
Side Effects: Sedation, fatigue, restlessness, neutropenia, leukopenia.
Side Effects: Abd. cramping, diarrhea,  MM resistance to acid, colic, HCl
can damage tooth enamel Nursing implications: Mental status, GI complaints.
RN implications: Monitor for abd pain, colic.
Trade Name: Zofran (ondansetron)
Vitamins B1 (thiamine), B2 (riboflavin), B3, (niacin), B6
(pyridoxine), nicotinamide, C (ascorbic acid) Classification: Antiemetic

Classification: Water Soluble Use(s): Prevention of N/V

Use(s): B1 -beriberi, B2 -skin, eyes, B3-pellagra, B6 seizures, C-scurvy Action: Blocks serotonin
Action: Catalysts for biochemical and metabolic reactions.
Contraindications: Hypersensitivity
Contraindications:
Side Effects: Diarrhea, dizziness, drowsiness, fatigue.
Side Effects: Generally water soluble vitamins are nontoxic b/c
Nursing implications: For hypersensitivity
excesses are excreted in urine.

Nursing implications: Monitor for S/S of allergic reactions to


parenteral thiamine.

Trade Name: Folic Acid Trade Name: Atropine Sulfate


Classification: Vitamin Classification: Antidysrhythmic, anticholinergic, parasympatholytic

Use(s): To assist with a normal pregnancy. Use(s): Bradycardias, blocks vagal response, pre-surgery to decrease
secretions, increase heart rate and dilate pupils
Action:
Action: Blocks ACH at parasympathetic receptors, decreases oral and
Contraindications: respiratory secretions, muscarinic antagonist drug

Side Effects: Allergic bronchospasm, rash, Pruritis, Erythema, malaise. Contraindications: Hypersensitivity to belladonna alkaloids,
tachycardia, GI obstruction, closed angle glaucoma, paralytic ileus
Nursing implications: A client trying to get pregnant should take folic
acid 3-6 months before conception. Side Effects: Dry mouth, n/v tachycardia, blurred vision, decrease
perspiration, constipation, urinary retention

Nursing implications: I&O, EKG, respiratory status


Trade Name: Riopan
Classification: Antacid

Use(s): Antacid, PUD, gastric ulcers, indigestion.


Trade Name: Calcium
Action: Neutralizes gastric acidity.
Classification: Electrolyte
Contraindications: hypersensitivity to this drug or aluminum
Use(s): To manage hypocalcemia, to prevent deficits.
Side Effects: Constipation, diarrhea, hypermagnesemia
Action:
Nursing implications: GI status, Serum MG++ Levels if decreased liver
Contraindications: Hypercalcemia, renal calculi, dig toxicity, V-Fib. function. Give after meals and atbedtime

Side Effects: N/V, pain, constipation, drowsiness, muscle weakness, HA.

Nursing implications: Assess the need for Calcium intake.

Trade Name: Antivert (meclizine)


Classification: Antiemetic, antihistamine, anticholinergic Trade Name: Anectine

Use(s): Vertigo, motion sickness Classification: Neuromuscular blocker

Action: Acts by blocking the chemoreceptor trigger zone Use(s): Skeletal muscle relaxant

Contraindications: hypersensitivity to cyclizines, shock. Action: Inhibits transmission of nerve impulses

Side Effects: Drowsiness, fatigue Contraindications: Hypersensitivity, Malignant hypothermia,


penetrating eye injuries.
Nursing implications: V/S, signs of toxicity
Side Effects: Sinus arrest, dysrhythmias, prolonged apnea,
bronchospasm.

Nursing implications: Electrolyte imbalances, I&O ratio, allergic


reactions.
Trade Name: Inapsine Trade Name: Tagamet
Classification: neuroleptic Classification: H2-histamine receptor antagonist

Use(s): postoperatively for N/V Use(s): Short term treatment of GERD, duodenal and gastric ulcers

Action: Acts on CNS at subcortical level, produces, tranquilization, sleep, Action: Inhibits histamine at the gastric acid site which inhibits secretion
Antiemetic.
Contraindications: Hypersensitivity
Contraindications: Hypersensitivity, child <2 years old, pregnancy,
lactation. Side Effects: Convulsions, paralytic ileus, jaundice, neutropenia,
increased PTT.
Side Effects: Laryngospasm, bronchospasm, Tachycardia, hypotension.
Nursing implications: Assess I&O, bun, Creatine, and a CBC with
Nursing implications: Vital signs. differential monthly.

Trade Name: Robinul (glycopyrrolate)


Trade Name: Kytril (granisetron)
Classification: Cholinergic blocker, anticholinergic
Classification: Antiemetic
Use(s): decreases secretions before surgery, PUD, Irritable bowel,
Use(s): Prevention of N/V reduces gastric secretions

Action: Blocks serotonin Action: Inhibits Ach in the autonomic nervous system

Contraindications: hypersensitivity Contraindications: Hypersensitivity, narrow angle glaucoma, child <3


Y.O., MI.
Side Effects: HA, anxiety, bronchospasm, leukopenia
Side Effects: Dry mouth, constipation.
Nursing implications: For Hypersensitivity reactions
Nursing implications: I&O, constipation, mental status.
Trade Name: RID
Classification:

Use(s):
Trade Name: Gelsolin
Action:
Classification:
Contraindications:
Use(s):
Side Effects:
Action:
Nursing implications:
Contraindications:

Side Effects:

Nursing implications:

Trade Name: Triple Dye


Classification:
Trade Name: DNase
Use(s): Prevent infection of umbilical cord and promotes drying of the
Classification: cord

Use(s): Action

Action: Contraindications:

Contraindications: Side Effects:

Side Effects: Nursing implications:

Nursing implications:
Trade Name: Silver nitrate Solution
Trade Name: Multi-Vitamins
Classification:
Classification: Vitamins
Use(s):
Use(s): To prevent birth defects
Action:
Action:
Contraindications:
Contraindications:
Side Effects:
Side Effects:
Nursing implications:
Nursing implications:

Trade Name: Dermoplast


Trade Name: Bicitra
Classification: OTC
Classification:
Use(s):
Use(s):
Treating metabolic acidosis and certain kidney problems Action:
(eg, kidney stones).
Contraindications:
Action:
Side Effects:
Contraindications:
Nursing implications:
Diarrhea; loose stools; nausea; upset
Side Effects:
stomach; vomiting
Nursing implications:
Trade Name: Americain Spray Trade Name: Masse Cream
Classification: OTC
Classification: OTC
Use(s):
Use(s):
Action:
Action:
Contraindications:
Contraindications:
Side Effects:
Side Effects:
Nursing implications:
Nursing implications:

Trade Name: Tucks Trade Name: Witch Hazel


Classification: Astringents-OTC Classification: Astringents-OTC

Use(s): Use(s):

Action: Action:

Contraindications: Contraindications:

Side Effects: Side Effects:

Nursing implications: Nursing implications:

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