Between you and the rest of the world

lies an interface

that makes up 16% of your physical weight.

This is your skin, the largest organ

in your body:

laid out flat, it would cover close to

1.7 square meters of ground.

Its purpose may seem obvious—

to keep our insides in.

But a look beyond the surface

reveals that it plays a surprising

number of roles in our lives.

First, the basics.

Skin is the foundation

of the integumentary system,

which also incorporates your hair,

nails, and specialized glands and nerves.

Made up of three layers,

the epidermis,

dermis,

and hypodermis,

skin’s thickness varies

from 0.5 millimeters at its thinnest

and up to four millimeters

at its thickest.

It also carries out three key functions:

protecting,

regulating,

and sensing the world beyond its limits.

On a daily basis, its huge surface

processes hundreds, if not thousands,

of physical sensations,

relying mostly on large,

pressure-sensitive skin components

called Merkel cells.

In your fingertips alone,

there are 750 Merkel cells

per each square-centimeter of skin,

coupled with over 2,500 receptors

that give you your sense of touch.

This surface is also the body’s first

major line of defense.

Without it, you’d be a soggy mass

of tissue and fluids,

fatally exposed to the elements.

Skin effectively seals off your insides

and also absorbs pressure and shock

with flexible collagen

that makes up most of its dermal layer.

The epidermis is made up mainly

of skin cells called keratinocytes

that are completely replaced

every four weeks.

As new cells form at the base of the

epidermis, older ones are pushed up.

When these cells move upwards,

they’re filled with a hardened protein

called keratin.

Once they reach the surface,

they form a tightly-overlapping,

waterproof layer

that’s difficult for invading

microbes to breach.

Any harmful microbes that make it

into the epidermis

will encounter Langerhans cells.

This group of protective skin cells

detects invaders

and communicates their presence

to resident immune system T-cells,

which react by launching

an immune response.

A crucial feature of this immune defense

is the several thousand

species of microorganisms

that inhabit the planes,

folds,

and crevices of your skin.

These microbes,

which include bacteria and fungi,

thrive in the sebum,

an oily substance that’s secreted

onto the skin’s surface

by sebaceous glands nestled

inside the dermis.

These skin microbes keep the immune system

in a state of constant surveillance,

ensuring that it’s ready to react

if the body really is at risk.

Beyond this protective role,

your skin is also a sensory organ that

helps regulate your body’s temperature,

two roles that are closely interlinked.

Nerves detect whether your skin

is warm or cold

and communicate that

information to your brain.

In return, the brain instructs

localized blood vessels

to either expand if the body is too warm,

releasing heat from

the blood through the skin,

or to constrict if the body is cold,

which retains heat.

At any given time, up to 25% of the body's

blood is circulating through the dermis,

making this process extremely efficient.

Under warm conditions,

the skin’s sweat glands will secrete sweat

via ducts onto the surface,

transferring heat out of the body.

Hair can also be stimulated

to conserve or release body warmth.

The average human

has 5 million hair follicles

embedded everywhere on the body

except the palms of your hands

and soles of your feet.

Ninety to 150,000 of those

are on your scalp,

where they help shield

the large surface area of your head

from physical damage and sunburn.

When you're cold, tiny muscles

called arrector pilli

cause hair to stand upright

across the body.

That’s the phenomenon known as goosebumps

and it traps body heat close to your skin.

Skin’s vast surface isn’t just a shield;

it also enables us to interact

and connect with the world.

Its multifunctional layer cools us down

and keeps us warm.

The integumentary system

may be many things,

but it’s certainly more than skin deep.