PCTE Group of Institutes,

Ludhiana

BMLS 6th Sem

APPLIED HEMATOLOGY

P RESENTATION S YNOPSIS

TOPIC: Idiopathic Thrombocytopenic Purpura

NAME: Sayyed Junaid Kazmi
UNIV.ROLL.NO: .1929437
OFFICIAL E-MAIL ADDRESS:
junaidpctebmls19@gmail.com

TABLE OF CONTENTS:
v Introduction
v Types of ITP
v Causes
v Sign and symptoms
v Lab Diagnosis
v Treatment
v References
BRIEF INTRODUCTION OF TOPIC:-
q Introduction:-Immune thrombocytopenic purpura (ITP) is a
blood disorder characterized by a decrease in the number of
platelets in the blood.

Meaning of
 “Thrombocytopenic”
“Idiopathic”
“Purpura”

TYPES
• Acute thrombocytopenic purpura:-  This usually affects
young children, ages 2 to 6 years old. 
• Chronic thrombocytopenic purpura. The onset of the disorder
can happen at any age, and the symptoms can last a minimum of
6 months, several years, or a lifetime. 

CAUSES
• Infections, typically viral infections, including the
viruses that cause chicken pox, hepatitis C, and AIDS,
can prompt antibodies that cross-react with platelets.
• Medication Can cause an allergy that cross react with
platelets
• Pregnancy
• Immuno disorder

SIGNS AND SYMPTOMS

by Email

LAB DIAGNOSIS
• Complete blood count
• Additional blood &Urine test
• Antiplatelet antibody testing
• BT :-Prolonged
• Tourniquet Test :-positive
• CT

#Peripheral blood

• Platelets count
BoneMarrow Examination

• Cellurity
• M:E ratio

TREATEMENT
• In children, ITP usually resolves without any treatment.
Adults commonly need treatment with medication for
bleeding. Rarely the spleen may need to be removed.
• Drugs that boost platelet production
• Immune globulin.
• Others drug
• Surgery

REFERENCES
• . Eddy DM: A Manuel for Assessing Health Practices and Designing
Practice Guidelines: The Explicit Approach. Philadelphia,
• PA, American College of Physicians, 1991
• 2. Woolf SH: Practice guidelines, a new reality in medicine. 11.
• Methods of developing guidelines. Arch Intern Med 152:946, 1992
• 3. Eddy DM: Practice policies: Where do they come from? JAMA
• 263:1265, 1990
• 4. Eddy DM: The challenge. JAMA 263:287, 1990
• 5. Field MJ, Lohr KN: Guidelines for Clinical Practice: From
• Development to Use. Institute of Medicine Committee on Clinical
• Practice Guidelines. Washington, DC, National Academy
Press,1999