Code No: R7602

R07
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
B. Pharmacy IV Year I Semester Examinations, November-2017
BIOPHARMACEUTICS AND PHARMACOKINETICS
Time: 3hours Max.Marks:80
JJN
Answer any five questions
All questions carry equal marks
NT
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TUU
1. Define pharmaco kinetics? Write the role of biopharmaceutics in development of
formulations. [16]
HH
2. Write the factors Influencing drug absorption? [16]

3. What is plasma protein binding and write the factors influencing protein binding?
[16]
UU
4. Write the significance of compartment modeling? Write the calculation of
SSE
pharmacokinetic parameters from urinary data? [16]

5. Write the dosage adjustment in patients with and without hepatic failure. [16]
EDD
6. Write the assessment of bioavailability. [16]

7. Write different in-vitro dissolution studies for solid dosage forms. [16]
PPA
8. Write short note on
a) In vitro-in vivo correlation
APP
b) Method of residuals. [16]
EER
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RS