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I. Overview
Dengue hemorrhagic fever is a more severe form of a viral illness. Symptoms include
headache, fever, rash, and evidence of bleeding (hemorrhage) in the body. This form of dengue
fever can be life-threatening and can progress to the most severe form of the illness, dengue
shock syndrome. This chapter reviews the etiology, epidemiology, diagnosis, pathophysiology,
transmissions, manifestations, diagnosis, treatment, and prevention of dengue.
Dengue fever causes a high fever — 104 F (40 C) — and any of the following signs and
symptoms:
● Headache
● Muscle, bone or joint pain
● Nausea
● Vomiting
● Pain behind the eyes
● Swollen glands
● Rash
Most people recover within a week or so. In some cases, symptoms worsen and can
become life-threatening. This is called severe dengue, dengue hemorrhagic fever or dengue
shock syndrome.
Severe dengue happens when your blood vessels become damaged and leaky. And the
number of clot-forming cells (platelets) in your bloodstream drops. This can lead to shock,
internal bleeding, organ failure and even death.
You have a greater risk of developing dengue fever or a more severe form of the disease
if:
● You live or travel in tropical areas. Being in tropical and subtropical areas
increases your risk of exposure to the virus that causes dengue fever. Especially
high-risk areas include Southeast Asia, the western Pacific islands, Latin America
and Africa.
● You have had dengue fever in the past. Previous infection with a dengue fever
virus increases your risk of severe symptoms if you get dengue fever again.
Complications (DHF)
a. Metabolic acidosis
b. Hyperkalemia
c. Tissue anoxia
f. Myocarditis
II. PATIENT’S PROFILE
According to the patient, she had experienced cough, fever, cold and chickenpox before. She
doesn't have any allergies to food or any medications. She has no history of hospitalization or any
surgery before but seeks medical advice to clinics in their barangay and other clinics to the nearby
towns.
The patient is a 17 y/o female, prior to admission the patient was experiencing fever, loss of
appetite and epistaxis so the family decided to take him to the hospital.
Upon interviewing the patient it was stated that the patient is the only child living with her
mother and his father is an OFW in Dubai. It was also stated that the patient is very active and plays a lot
outside.
IV. ANATOMY AND PHYSIOLOGY
Platelet
A tiny, disc-shaped piece of cell that is found in the blood and spleen. Platelets are
pieces of very large cells in the bone marrow called megakaryocytes. Platelets circulate in blood
plasma and are primarily involved in hemostasis (stopping the flow of blood during injury), by
causing the formation of blood clots, also known as coagulation. The adhesive surface proteins
of platelets allow them to accumulate on the fibrin mesh at an injury site to form a platelet plug
that clots the blood. The complex process of wound repair can only begin once the clot has
stopped bleeding.
Bone Marrow
Bone marrow is a spongy substance found in the center of the bones. It manufactures
bone marrow stem cells and other substances, which in turn produce blood cells. Each type of
blood cell made by the bone marrow has an important job. Red blood cells carry oxygen to
tissues in the body
V. PATHOPHYSIOLOGY (in flow chart)
Complication:
Dengue shock syndrome. Common symptoms in impending shock include abdominal pain, vomiting,
and restlessness.
VI. DIAGNOSTIC TESTS
A. Laboratory
B. Radiologic Test
Clinical Instructor_________________________________