Product Information

S2134 AZD8330
MEK

Novel Life Science Reagents

for Cell Signaling Research

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Technical Data:
M.Wt: Formula: Solubility: Purity: Storage: CAS No.: 461.23 C16H17FIN3O4 Unknown 99% at -20 2 years 869357-68-6
I F O H N N O H N O OH

Orders
+1-713-922-4115 enquiry@selleckchem.com

Tech Support
tech@selleckchem.com
(chemistry support)

Synonyms: ARRY-424704, ARRY-704

techbio@selleckchem.com
(bio support)

Biological Activity
AZD8330 is an orally active, selective MEK inhibitor with potential antineoplastic activity. It specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth. Constitutive activation of this pathway has been implicated in many cancers. [1]

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References
[1] http://www.cancer.gov/drugdictionary/?CdrID=543526

Return Policy
Please inspect packages immediately upon receipt and notify customer service within 3 days of delivery of any damage or discrepancies.Our team will take quick and appropriate action to correct any problem.

MSDS & CoA

Please visit www.selleckchem.com to download MSDS and CoA.

Goods ordered in error can only be accepted for return if made within 3 days of delivery, are unopened,have been stored correctly and are in good condition. Should you wish to return any item(s), prior authorization must

Notes
PLEASE KEEP THE PRODUCT UNDER -20 FOR LONG-TERM STORAGE. NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
Specific storage and handling information for each product is indicated on the product datasheet. Most Selleck products, stored under the recommended conditions, are stable for two years. Products are sometimes shipped at a temperature that differs from the recommended storage temperature,most are recommended stored at -20 Many products are stable in the short-term at temperatures that differ from that . required for long-term storage. We ensure that the product is shipped under conditions that will maintain the quality of the product, but save your shipping charges by using the most economical storage conditons for an overnight shipment. Upon receipt of the product, follow the storage recommendations on the product data sheet.

be received from our customer service team. Returns accepted will be subject to a 30% restocking charge.

For all product returns and product replacements,please contact Selleck directly by info@selleckchem.com or +1-713-922-4115 Please have on hand, the invoice number, purchase order number,air bill number and approximate date of shipment/receipt.

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