Professional Documents
Culture Documents
General Pharmacy
General Pharmacy
d. act with fairness, to allow people to receive that to which they are entitled.
e. act with honesty, without deception.
NB.Autonomy: respect the person and their right to determine their own actions.which contains
Veracity: need to be honest with patients.
Confidentiality & privacy
Fidelity: promise to care
Nonmaleficence: need to avoid harm
Maleficence: need to do what benfits patients
Justice: need to treat patients fairly
4-Which of the following need. referral to doctor:
A- Diabetic patient with diarrhea more than 36 hrs.
B- 8 years old child with diarrhea more than 36 hrs and fever (38°C)
C- Adult with diarrhea more than 4 days.
A&B A&C B&C A&B&C
6-a regular customer to your pharmacy came with a RX but from your record u
discovered a drug _drug interaction between the new and the old
medications .what is your best action:
A.refuse to issue the RX
B.tell the pt about the drug interaction and send him to the doctor
C.call the doctor and tell him to change the drug to avoid interaction
7-patient need to refill prescription but the dose is not appearing clearly what you should
do? Call the doctor and ask him about the dose
7’- a prescription come to you with a confusion dosage form with a different route
of administrations:
A.Return the Rxs to the doctor
B.Add details and instructions about the different route of administration in the
prescription
7”- For dosage that may develop confusion for the route of administration ; as
pharmacist as if what of the following you will do or act
A. Remove label and cancel it
B. Write the expiry date on the label
C. Write the right method of administration on the label
D. Return the whole prescription to the Dr
a) 24 hrs Pharmacy
b) In patient pharmacy
c) Outpatient pharmacy
d) Drug store
e) Scientific Office
f) Door to door pharmacy
1. A & c
2. D & F
3. A only
4. F only
12-About missed or broken ampoule .how to keep them in HAAD section in pharmacy?
12”- if a controlled medication has been missed, returned ,expired or the ampule
broken ,How you will inform HAAD
a. Put in black disposable bag
b. put in secure bag then send it to HAAD
c. send report to HAAD (2nd)
13-you found that they issued an expired medication from your stock. what is your
action:
A. call and inform the prescriber.
B. document the medication error to haad
C . Try to contact pt to return medication .
D.a+c
16- Diaphragm 1:
1. MTC mean: minimum toxic concentration
2. MTC means
a- Maximum toxic conc.
b- Maximum safe conc.
18-AUC measured by
Tripzoidal method
_linear
_triangle
19-In high therapeutic index:
b- a-more toxicity
c- b-no side effects
22-Diaphragm 2
a.used in emergency
c.fastest
answer..A ,B,C
N.B.: DRY : gum and oil are triturated and water added at once
WET : gum and water are triturated and oil added slowly
30-emulsion inversion:
a-conversion of W/O emulsion to O/w emulsion and vice versa
NB. if water is internal phase so classified W/O and if water is the external phase
then O/W
1- Aqueous
2- Non aqueous
3- Aqueous and non aqueous
4- Oily
NB. As the dispersed phase is usually the oil droplets while the liquid is called the
dispersion medium or continuous phase
31”-If the emulsion passed the conductivity test, which one is the dispersed
phase?
-Aqueous
- Non-aqueous
-Lipoid
-Both aq and non-aq
33- Conductivity test – Dilution test – Dye test used for which dosage form :
a. Susp.
b. Emulsion
c. Foam
d. Gel
Cracking
35’’- Oil droplets on surface of emulsion and when mixed become homogenous what
is it called
Creaming
37-cold cream
a.w/o emulsion
b.o/w
c.w/o/w
38- positive & negative particles mixed together with water is called
Emulsification
1- Suspend ability
2- Penetrability
3- Dissolution rate
4- Dose to dose uniformity
5- Uniformity of tablet
6- All of the above
a. Particle size
b. Size distribution
c. Interaction with surface molecules
1)a only
2)a+b
3)a+b+c
4)b+c
43”- If two drugs are pharmaceutically equivalent which statement is not true (not
sure)
* they have the same active ingredient
* they have same dosage form
*they have same route of administration
* they are bioequivalent
NB.Bioequivalent: same rate & extent of drug absorption for the generics .
43’’’-if a drug has the same active ingredient like other drug but not contain the
same inactive ingredient this mean :-
a- Bioequivalent
b-pharmaceutical equivalent
c- pharmaceutical alternative
d- A,B
44- if a drug has the same action like other drug but not contain the same active
ingredient this mean
a- Bioequivalent
b- pharmaceutical equivalent
c- pharmaceutical alternative
d- A,B
b) Same therapeutic moiety but Different dosage forms and strengths within
a product line by a single manufacturer .
c) A+B
47-A-faciliated diffusion
47’-facilitated diffusion is
need transporter ,down chemical gradient required, glycoprotein used , all are true
49-CDA written on Sunday , what’s the last day to dispense it on the week :
d. Tuesday
49’-a narcotic prescription written on Sunday. The last day to dispense :
2) A.tuesday
3) B wed
4) C.Thur
NB. The prescription must be written maximum 2 days earlier as only valid for 3 days .
50-the expiration date on original package NOV 2015 today is 1 DEC 2014 : the
pharmacist repackaged the medicine with FDA guidelines :25% of remaining time
on the original package to max. 6 months what is the new expiration date :
FEB 2015
May 2015
Jan 2015
June 2015
NB. The ans. Is feb.2015 ( cause it mentions 25% u will add 3 months ) and if it doesnt
mention so the ans. Will be may 2015 ( add 6 months)
NB.The general rule for expiray of drugs after open is max 6 months but some times they mentioned
the percent of remaining as 25% for example if the remaining time for expiry as mentioned by the
manufacture is 12 months the 25% of it is 3 months
so if u open it you have only 3 months to use but if this remaining is much more and after calculating
the 25% of remaining u found it more than 6 months for example it was 8 months u have max 6
months to use
54-semi control is
Controlled Drug class B no need for control prescription like control
drug class A.
57-Controlled drug:
licensed GP can prescribed for only 3 days
refill must not be issued for control medicine
duration of Rx to be dispense is no more than 2 days from the Rx date
all (answer is all)
NB. A HAAD licensed Specialist must only prescribe up to 15 days of Controlled
medicines. 6.3.3 A HAAD licensed Consultant and specialist in Neurology or
Psychiatry must only prescribe up to 30 days of controlled medicines(also these
choices true if come in question)
61-generic drug is
a-drug not under protection of generator company
b- Drug not manufactured by the generator company
61’-generic drug:
a-name of active ingredient
b-drug that has same active ingredient but differ in excipient
c-drug that is not manufacture by the generator or a company that belong to
d.(b&C)
NB. Diluents: provide bulk to the tablet (also in capsules): Dextrose, Lactose, sucrose, starch &
microcrystalline cellulose
-Glidant: Improve flow properties of powders and granules also during filling capsules
[ Starch, colloidal silica , Silica, & talc]
-Lubricants: Mg stearate (capsules & tablets), talc stearic, PEG, SLS
-Preservatives: Methylparaben, potassium sorbate, benzyl alcohol, benzalkonium chloride
-Solvents: Ethanol & PEG polyethylene glycol.
63- Which of the following ingredient will help in mixing the whole ingredients
together by process of gliding
a. Talc
b. Sugar
c. Titanium oxide
d. SLS
NB. Talc is a glidant.
71-Patient came to the pharmacy, he was angry and shouting he want to buy a
medicine but as a pharmacist following the rules only can give (medicine Sold)
-Original Packet
-pack
-leaflet
-strip
- ALL
NB. they said there was a choice of giving the pt the drug with a copy of the leaflet and
they choose it
71’-medicine sold as
- Pack
- Part with name and expire
- Patient take copy of leaflet
76- In which phase of drug investigation is the efficacy and the dose of drug
determined to be used in further trials?
a) Phase 1
b) Phase 2
c) Phase4
d) phase3
77- In which phase of drug investigation is the dose of drug determined to be used
in further trials?
a) Phase 1
b) Phase 2
c) Phase4
d) phase3
NB. Steps of new drug investigations:
Preclinical: on animals pharmacology and toxicology.
Phase 1: : assessment of safety , drug tolerability , dose usually in healthy volunteers
Phase 2: assessment of efficacy & safety in patients with the disease or condition
Phase 3: large scale, multi centered study.
Phase 4: after FDA submitting clinical studies on the finished, marketed product, post marketing surviliience
Phase 5: after FDA approval modifications in formulation .
Regarding FAD Regulations, When the manufacturer (developer) must register -’77
:the item in FDA
A- From the beginning (Raw material)
B- Before you test in patient
C- Before you test it in human volunteers
D- Before you make a toxicology test in lab animals
79’’-Definiton of formulary:
*some notes:
1-drug international compendium >>>>martindale
2-to obtain chemical information and drug information >>>>>medline
3- to search for purity and chemical structure >>>>pharmacopiea
4- free engine research ,online books >>>>pubmed
5- primary literature >>>>>>journal and clinical data (abstract)
6-electronic data base >>>>medescape
87- After circulation of certain drug, it proven that it cause severe hemorrhage
the FDA decide to stop this circulation, this is called:
1-drug recall class I
2-II
3-II
4-none of these
Class II recall: a situation in which use of or exposure to a violative product may cause temporary or
medically reversible adverse health consequences or where the probability of serious adverse health
consequences is remote.
Class III recall: a situation in which use of or exposure to a violative product is not likely to cause adverse
health consequences.
88-if an interaction decreases the Bioavailability of other drug , this means that
a- absorption of the drug increase
b- renal excretion of the drug increase
c- metabolism of the drug decrease
d-dose of this drug may need to be increased.
104-As a pharmacist how can you know that a patient comes to your pharmacy has a
vision problem:
Wearing thick glasses
Looking as doggy eyes
Wearing black glasses
All of the above
105-The aim of auxiliary label is to : or cautionary or advisory label
" provide additional information about a drug
-colorimetery test
All
Improve compliance
All
Which part of the component considered as the heart of the can ? -125
A.valve
B.propalent
C.tube
?Which of the following gases are used as a propellant in aerosol container -126
A.carbon dioxide
B. Hydrocarbon
C.trifluromethane
d.all
nitrous oxide, nitrogen
127-Increased volume of distribution mean?
A-Too much drug bind to tissue
B- Binds to plasma protein
C-Increase the excretion
D-Too little drug bind to tissue
128-patient came to pharmacy and bought a UTI indicator test, which of the
following is true?
A.it’s a test that convert dietary nitrite to nitrous
B. it’s a test that indicate anaerobic bacteria only
C.it’s a case that indicate gram positive bacteria only
D.it’s a kit that contains 30 dipstick in a packet
132- first thing we test in product before submission ( Fundamental test for new
drug)
Intrinsic solubility and dissolution constant
133-phenol is a
Carboxylic acid
Carbolic acid
Carbonic acid
NB. phenol is carbolic not carboxylic (the carboxylic form is called benzoic acid)
135-abtout Clearance law :
a.cl=er(q)
b.cl=vd*k
c.cl=css/Q
d- all
136- Alcohol may be incorporated at which of the following dermal preparations
a- lotions
b- ointments
c- suppositories