2

BA
23 OT

e21o1 -2
212{©1S

+R--oR' ResluxK R- +R-ot

Slo, ADS Rst

Ho?+G-or
>
OR

R
i A
 poton
shis+
H -2 + :R Fat +R-H

2tt24

21 221SG
A

qptea5 aiv RDS - Rate

determimng Step)
1131mh OA

1b Csimolea,ar
 213Gug s
Stoyfsyens s egiSt1s
go KsA

H
ch + <st,pr
H +H -o«sH,
Resx
ch

OH +H ö-H H + ot

So, RDS
HE oesR H (8 5st
 P.S.
Fas+
R.
CH
CH

o
AA
T
to 1 s o)
512sac) on
13ts 1B2 )
on

1stos . Aa
Usa

R--oR + H2

AA2
on
 Ap
ot
SloRDS
R
- H,e

2-2 Xi2i2s i2-24 Fas+ H

2a dtEam
Paoton OH
Shist Fas* R-H
R OR' Ris4
R
protan shis+ +R-OH
Fas OR
slow, RDS OH

s21012107 2s
-H Fas
R
Fest
OH
 innY184) (
Ss

Grai
C G1E a)
27 So
onshra GtS
O

s 2iI21a

1311m

111asa K
 hs
d .

221S GrorG

Gis S

2n2s
GaIG
 H
Hooc-chz-Ct, -e-scks+H2 Hooc-ch-<H-:
SHoi2 + C2HsoH

Hooc-C,-ch<-ocaHs Kooc- cH-Ck2 -2ts

P.S.
Slo, RDS
Hoo <H-CH, S
-H2, Fs+ P.s.s+

-H .
Fast
HooC-cH2-<t, HoocCR-CA
+C21sH
Fest
H
SloaRDS
 2

O
HShns
buc- SrS o o

A 2
E'h G