Professional Documents
Culture Documents
Theories of Aging
No single theory has been deemed the cause of aging
rather there are many theories from a number of disciplines that
overlap. If this is the case ,there must be a way to delay aging, thereby
increasing lifespan.
Theories of Aging
Biologic Theories
Stochastic Theories
Non-stochastic Theories
Psychosocial Theories
Sociological Theories
Psychological Theories
Nursing Theories
Biologic Theories:
ALSO:
all organs in any one organism do not age at the same rate
any single organ does not necessarily age at the same rate in
difference individuals of the same species
Stochastic Theories
SOURCES OF ROS:
• External Sources:
⁃ Ionizing radiation- gamma rays, UV rays, xrays, Ultraviolet rays
⁃ Pollutants- fumes, smoking, cigarettes
• Internal/Intrinsic Source:
⁃ ETC- Electro transport Chain-most common (Macrophages)
Defenses to ROS:
Exist in two main group:
Enzymes and Small molecules antioxidants
• Antioxidants delay or inhibit oxidative damage,
• capable to neutralize free radicals by donating electrons,
• prevent cell damage and tissue damage,
• and act as Scavenger
Lipofuscin Theory
⁃ Moreover, there has been considerable interest in the role of
lipofuscin “age” pigments”,
⁃ A lipoprotein by-product of oxidation that can be seen only under
a fluorescent microscope in the aging process.
⁃ Because lipofuscin is associated with the oxidation of
unsaturated LIPIDS, it is believed to have a roles similar to that
of free radicals in the aging process
⁃ As lipofuscin accumulates, it interferes with the diffusion and
transport of essential metabolites and information- bearing
molecules in the cells.
⁃ A positive relationship exists between and individual’s age and
the amount of lipofuscin in the body.
2. Cross-Linkage Theory
• Also referred to as the Glycosylation Theory of aging
• Proposed by Johan Bjorksten in 1942.
• According to this theory, an accumulation of cross-linked proteins
damages cells and tissues, slowing down bodily processes resulting in
aging.
• In this theory it is the binding of glucose (simple sugars) to protein, (a
process that occurs under the presence of oxygen) that causes various
problems.
• Once this binding has occurred the protein becomes impaired and is
unable to perform as efficiently.
• Some research supports a combination of exercise and dietary
restrictions in helping to inhibit the cross-linkage process
4. Evolutionary Theories
• These theories of aging are related to genetics and hypothesize
that the differences in the aging process and longevity of various
species occur due to interplay between the processes of mutation
and natural selection (Ricklefs,1998; Gavrilov and Gavrilova,
2002).
• Attributing aging to the process of natural selection links these
theories to those that support evolution.
Nonstochastic Theories:
2. Genetic Theory
⁃ Programmed Theory of Aging
⁃ This theory advocates that animals and humans are born
with a genetic program or biological clock that
predetermines the life span (Hayflick, 1965).
⁃ It asserts that aging follows a biological timetable
based on a person's genetics.
⁃ Various studies support this idea of a predetermined
genetic program for life span
(eg. Studies have shown a positive relationship between
parental age and filial life span
⁃ Error Theory
⁃ This theory suggest that, overtime, cells accumulate
errors in their DNA and RNA protein synthesis that
causes cells to die.
⁃ Causes of Errors: Environment factors and randomly
induced events
⁃ X-ray radiation - chromosomal abnormalities
5. Radiation Theories
⁃ The relationship between radiation and age continues to be
explored.
⁃ Repeated exposure to ultraviolet light is known to cause solar
elastosis, (the old ‘’ old age’’ type of skin wrinkling that results
from the replacement of collagen by elastin)
⁃ Ultraviolet light is also a factor in the development of skin
cancer.
⁃ Radiation may induce cellular mutations that promote aging.
6 Nutrition Theories
⁃ The importance of good nutrition throughout life is a theme hard
to escape in our nutrition – conscious society. It is no mystery
that diet impacts heath and aging. Obesity is shown to increase
the risk of many diseases and shorten life ( NIDDK, 2001;
Preston, 2005: Taylor and Ostbyte, 2001.
⁃ The quality of diet is as important as the quantity. Deficiencies of
vitamins and other nutrients and excesses of nutrients such as
cholesterol may cause various disease processes.
⁃ Recently, increased attention has been given to the influence of
nutritional supplements on the aging process; vitamin E , bee
pollen ginseng, gotu kola, peppermint, and kelp are among the
nutrient believed to promote a healthy, long life ( Margolis, 2002;
Smeeding, 2001)
⁃ Although the complete relationship between diet and aging is
not well understood, enough is known to suggest that a good
diet may minimize or eliminate some of the ill effects of the
aging process.
7. Environmental Theories
⁃ Several environmental factors are known to threaten health and
are thought to be associated with aging process.
⁃ Examples:
⁃ Ingestion of mercury, lead, arsenic, radioactive isotopes,
certain pesticides, and other substances
⁃ Smoking and breathing tobacco smoke and other air
pollutants
⁃ Crowded living , high noise levels,
PSYCHOSOCIAL THEORIES
1. Disengagement Theory
⁃ The basis of this theory arises from the fact that human beings are
mortal and must eventually leave their place and role in society.
Therefore, it is their responsibility to look for suitable
replacement.
⁃ It views aging as process in which society and the individual
gradually withdraw, or disengage, from each other , to the
mutual satisfaction and benefit of both. The benefits to
individuals that they can reflect and be centered on themselves
have been freed from social roles.
⁃ The value of disengagement to society is that some orderly means is
established for the transfer to power from the old to the young,
making it possible for society to continue functioning after its
individual members die.
⁃ The theory does not indicate whether society or the individual
initiates the disengagement process.
⁃ However, it been observed that many older persons desire o remain
engaged and do not want their primary satisfaction to be derived
from reflection on younger years.
⁃ Examples: Senators, Supreme Court Justices, College Processors,
and many senior volunteers are among those who commonly
drive satisfaction and provide a valuable service to society by
not disengaging
3. Continuity Theory
⁃ The continuity theory proposes that older adults maintain the
same activities, behaviors, personalities, and relationships of the
past.
⁃ Old age is not a separate phase of life, but rather a continuation
and thus an integral component
6. Gerotranscendence
⁃ It suggests that aging undergoes a transition from a rational,
materialistic perspective towards oneness with the universe.
⁃ As people age, they are less concerned with their physical
bodies, materials possessions, meaningless relationships, and self-
interests and instead desire a life of more significance and a greater
connection with others.
⁃ Characteristics of successful transformation includes:
⁃ a more outward or external focus,
⁃ accepting impending death with fear
⁃ an emphasis on substantive relationships
⁃ a sense of connectedness with preceding and future
generations
⁃ and spiritual unity with the universe.
2. Theory of Thriving
⁃ This theory proposes that everything that impacts people
throughout their lives must be linked to create a holistic view of
aging (Haight, Barba, Tesh , and Courts, 2002)
⁃ Failure to thrive results from a discord between the
individual and his/her environment or relationships
⁃ Nurses identify and modify factors that contribute to disharmony
among theses elements
⁃ The Theory is based on the failure to thrive concepts as it
related to other adults in nursing homes (Newbern and
Krowchuk, 1994): the clinical characteristics of older persons
experiencing failure to thrive include disconnectedness, inability
to find meaning in life, problems with social relationships, and
physical and cognitive dysfunction.
⁃ In contrast, thriving is possible when harmony exists between
individuals and their physical and human environment
⁃ the process of thriving is continuous and enables aging
individuals to find meaning in life and adapt to changes.
⁃ this theory reinforces the importance of nurses considering the
many factors that can impact healthy and quality of life for older
adults.
Six Positive Lifestyle Factors that Promote Good Health (Kirsti A. Dyer
MD, MS, FT Updated: June 11 2018)
1) Getting Regular And Adequate Amounts of Sleep
2) Eating Regular Well- balanced Meals, Including Breakfast
3) Engaging in Regular Physical Activities
4) Maintaining a Healthy Body Weight
5) Not Using Tobacco Products, Including Smoking or
Chewing
6) Using Alcohol in Moderation or Not at All
1. Learn about patient’s stories; ask about family backgrounds, faith, work
histories, hobbies, achievements and life experiences.
Encourage patient to discuss these topics, and listen with sincere
interest. Remember: The elderly needs someone to talk to.
2. Build on lifelong interests and offer opportunities for patients to
experience new pleasures and interests, e.g., threading beads to
make bracelets, necklaces, etc., growing plants in small pots; learning
how to paint; group singing; etc.
3. Accept patient’s discussions of their regrets and dissatisfactions. Help
them to put these in perspective of their total lives and
accomplishments.
4. Encourage reminiscence activities between patients and their families.
Help families and staff to understand the therapeutic value of
reminiscence.
5. Respect patient’s faith and assist them in the fulfillment of spiritual
needs (e.g., help them locate a church of their religious affiliation,
request visit from clergy, pray with or for them, and obtain a Bible or
other religious book).
6. Use humor therapeutically. “Laughter contributes to good health.”
7. If patients reside in an institutional setting (e.g., home for the aged),
personalize the environment to the maximum degree possible.
8. Recognize the unique assets and characteristics of each patient.
Implication to Nursing
Using knowledge gained from aging theories nurses can:
✓ Help people use their genetic make up to prevent comorbidities;
✓ Facilitate best practices for managing chronic illness;
✓ Maximize individual’s strengths relative to maintaining independence
✓ Facilitate creative ways to overcome individuals’ challenges
✓ Assist in cultivating and maintaining older adults’ cognitive status and
mental health.