1/26/22, 6:25 PM Quiz 2/1

Quiz 2/1 Total points 91/100

Name *

Faisal Ahmed

E-mail address *

faisalmalikmalik123@gmail.com

Group *

35-1a

Acute phase proteins classified as humoral factors of innate immune defense 2/2
*

True

False

Cathelicidins synthesized by neutrophils * 2/2

False

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1/26/22, 6:25 PM Quiz 2/1

True

It is possible to activate the complement system along the classical pathway 2/2
without the formation of immune complexes *

False

True

The synthesis of antibodies against thymus-independent antigens is provided 0/2

without the participation of macrophages and T-lymphocytes independently
by B-lymphocytes *

True

False

There are immunoglobulin antigen-recognizing receptors on the membrane 2/2

of T-lymphocytes and natural killer cells *

True

False

The IgG light chain is completely contained in the Fc fragment * 2/2

False

True
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1/26/22, 6:25 PM Quiz 2/1

Lymphocyte chemotactic factor is: * 5/5

IL-31

IL-8

IL-16

IL-1

TNF-α

Characteristic factors for the lectin pathway of activation: * 5/5

binding of the C1 component to the immune complex

participation of the properdin system

proteins

binding of MBL to mannose residues on the surface of microorganisms

participation of antibodies

binding of the C3 component to the bacterial polysaccharide

Biological effects of the complement system: * 5/5

immune adhesion

synthesis of antibodies

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1/26/22, 6:25 PM Quiz 2/1

formation of tolerance

specific cytotoxicity

anti-inflammatory action

B-lymphocyte marker is: * 5/5

СD 4

СD72

СD 2

СD16

СD 3

The immunoglobulin (Ig) molecule consists of: * 5/5

Non-covalently linked polypeptide chains

Two different heavy and two different light chains

Two identical heavy and two different light chains

Two identical heavy and two identical light chains

Two different heavy and two identical light chains

Which of the following statements is NOT refers to IgG? * 5/5

Opsonizes bacteria

Neutralizes bacterial toxins

Activates the complement system

Penetrates through the human placenta

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1/26/22, 6:25 PM Quiz 2/1
Penetrates through the human placenta

Occurs at an early stage of the primary immune response

What factors mediate the innate humoral immune response? * 0/7

Т-lymphocytes

В- lymphocytes

antimicrobial peptides

defensins

immunoglobulins

What is characteristic of the alternative pathway of complement system 7/7

activation: *

participation of С1 INA

binding of the C3 component to the bacterial polysaccharide

formation of the immune complex

activation of T-lymphocytes

participation in the activation of the properdin system

When blood group A isohemagglutinin IgM, previously treated with pepsin, is 7/7
added to human erythrocytes with blood type B, the reaction occurs ---------
------. *

lysis

precipitation

nothing happening

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1/26/22, 6:25 PM Quiz 2/1
agglutination

phagocytosis

________________ domain heavy and variable domain ___________ chains are 7/7
part of the active antigen-binding center of Ig: *

first constant

light

variable

second constant

heavy

In history a 3-year-old boy has a pneumonia more than once a year. In each 10/10
of the cases Streptococcus pneumoniae was identified as a pathogenic
flora. The child was treated with penicillin each time, he was discharged
from the hospital with improvement. When studying the levels of
immunoglobulins in blood serum, age-related normal values were revealed
for all isotypes of immunoglobulins, but serum levels of some complement
components were reduced. Deficiency of which of the following
complement components can explain frequent streptococcal pneumonias
in this patient? *

С2

С3

С1

С4

С5

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Tonsillectomy (surgery to remove the palatine tonsils) was very commonly 10/10
performed up until the 1970s in children. Currently this procedure has lost
its broad appeal as we have learned of the important role of mucosal-
associated lymphoid tissue (MALT) in a protective immune response. What
is the main immunoglobulin produced by MALT? *

Monomeric immunoglobulin capable of opsonization

Monomeric immunoglobulin that penetrates trough the placenta

Pentameric immunoglobulin that activates complement

Monomeric immunoglobulin associated with mast cells

Dimeric immunoglobulin with a secretory component

A 64-year-old man underwent surgery to remove a fragment of the colon 10/10

for adenocarcinoma. Pathological anatomical examination of the removed
tissue in the lumen of the colon revealed the presence of hyperplastic
Peyer's patches with IgA-secreting plasma cells, while secretory IgA was
absent. Which of the following changes in the intestinal epithelium can
explain this condition? *

Failed rearrangement of the variable domain gene segment

Absence of Th2

Absence of polyimmunoglobulin receptors

Absence of J-chain synthesis

Isotype switching failure of immunoglobulins

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1/26/22, 6:25 PM Quiz 2/1
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