4 types of Noncovalent

Interactions

Van der
Hydrogen Bonds Ionic Hydrophobic
Waals
 Structure and Polarity
Interaction of Water
Water molecules
Acid-Base Property
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Acids Bases Buffer
 Components and
Mechanism
Henderson-Hasselbalch
Buffer Equation
Examples in Living
Systems
NONCOVALENT INTERACTIONS

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 NONCOVALENT INTERACTIONS
Van der Waals

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NONCOVALENT INTERACTIONS
Ionic

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 NONCOVALENT INTERACTIONS
Hydrophobic

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 NONCOVALENT INTERACTIONS
Hydrogen

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 The Solvent for Biochemical Reactions

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WATER: STRUCTURE AND POLARITY

δ+ Dipole: the condition of having positive

and negative charges

Largely determines the

δ- solvent properties of
water
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INTERACTION OF WATER MOLECULES

Hydration shell
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ACID-BASE PROPERTY OF WATER
Autoionization:

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ACID-BASE PROPERTY OF WATER
Autoionization:

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ACID-BASE PROPERTY OF WATER

Autoionization:

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ACID-BASE PROPERTY OF WATER

Autoionization:

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ACID-BASE PROPERTY OF WATER

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ACID-BASE PROPERTY OF WATER

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 A review

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 ACIDS VS BASES

Acids: proton donor Bases: proton receiver

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 ACID DISSOCIATION CONSTANT

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 BASE DISSOCIATION CONSTANT

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MEASURES OF ACIDITY/ALKALINITY

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MEASURES OF ACIDITY/ALKALINITY

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MEASURES OF ACIDITY/ALKALINITY

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 BUFFER
The solution that resists change in pH.
In titration: pH plateaus at half-neutralization

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 HENDERSON-HASSELBALCH
EQUATION

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 HENDERSON-HASSELBALCH
EQUATION

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EXAMPLES OF BUFFERS IN LIVING
SYSTEMS

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THANK YOU!