Student’s Name: Kiara M.

Forcadilla Year Level & Section BSN 3B Date:

Pharmacological Nursing Study (Drug Study) Worksheet

Generic/Brand Dose Strength & Indication/ Mechanism of Adverse/Side Effects & Nursing Rationale Client Teaching Evaluation
Name & Drug Formulation Drug Action Drug Interaction Responsibilities
Classification
Anticholinergics Dose Strength: Indications: Adverse Effects: - Identify if the - To decrease the - Verbally instruct the - Observe the
Prescription medication CNS: headache, patient is level of risk on patient to report if a patient's
Generic Name: Preanesthetic used as an antidote for restlessness, insomnia, allergy to the having adverse sudden reaction response to
IV, IM, cholinergic drug overdose dizziness medication effects occurs the treatment
Atropine sulfate Subcutaneous: or mushroom poisoning as that will be (improvemen
ADULTS, ELDERLY: well as to treat the CV: bradycardia, given such as - Take the medicine on t in condition
Brand Name: 0.4–0.6 mg 30–60 symptoms of low heart palpitations, tachycardia with the specified time (for being
min preop. rate (bradycardia), lower atropine, tablet) treated).
AtroPen saliva and bronchial EENT: blurred vision, homatropine
CHILDREN secretions before to mydriasis, photophobia, and - Instruct the patient to - Observe for
Drug WEIGHING 5 KG surgery, and treat cycloplegia, increased scopolamine exert pressure negative
Classification: OR MORE: symptoms of bradycardia. intraocular pressure on during the impacts (e.g.,
0.01– 0.02 - Monitor vital - To determine administration of the photophobia,
Acetylcholine mg/kg/dose to EENT: blurred vision, signs such as the baseline ophthalmic solution heat
antagonist maximum of 0.4  Symptomatic mydriasis, photophobia, the blood assessment for and for one to two intolerance,
mg/dose. bradycardia, cycloplegia, increased pressure adjusting the minutes afterward urinary
Minimum dose: 0.1 bradyarrhythmia intraocular pressure urine output dose. (ophthalmic solutions) retention).
mg (junctional or and ECH
scape rhythm) GU: urine retention pattern. - Do not combine this - Tracking
CHILDREN  Antidote for medication with any patient
WEIGHING LESS anticholinesterase Other: anaphylaxis other medication
THAN 5 KG: -insecticide - Discuss the - To increase anticholinergics unles compliance.
0.02 mg/kg/dose poisoning nature of the understanding s specifically
30–60 min preop  Reducing drug to the of instructed to do so.
secretions and patient using pharmacologica
Bradycardia IV: inhibiting cardiac terms that is l therapy and - Avoid hazardous tasks
ADULTS, ELDERLY: related to encourage if dizziness,
0.5–1 mg q5min, vagal responses
not to exceed total prior to surgery
of 3 mg or 0.04  Adjunct treatment
mg/kg. of peptic ulcer
disease; functional
CHILDREN: GI disorders such
0.02 mg/kg with a as irritable bowel
minimum of 0.1 mg syndrome;
to a maximum of salivation and
0.5 mg as a single bronchial
dose. May repeat secretion
in 5 min. reduction; CNS
conditions such as
Maximum total parkinsonism;
dose: ureteral and
1 mg. biliary colic
 Acute Iritis
Formulation:
Atropine sulfate is
available in the Drug Action:
form of:
Tends to increase
 Tablet conduction across the AV
form node, inhibits
 Injection acetylcholine at the
form parasympathetic
 Ophthalmi neuroeffector junction,
c ointment blocks vagal actions on the
 Ophthalmi SA and AV nodes, and
c solution elevates heart rate. Blocks
in ophthalmic use pupillary
dilating and
accommodation paralysis
are brought on by
the patient’s compliance. drowsiness, or blurred
Side Effects: culture. vision occurs.
-
Frequent:
Throat, nose, and mouth
may be dry, diarrhea due to
decrease GI motility,
redness at the injection site
(which may be mild or
severe), and decreased
sweating
Occasional:
Dysphagia, blurred vision,
bloated feeling, impotence,
urinary hesitancy
Drug Interaction:
Drug: Drugs under
anticholinergics agents may
elevate the effects
Herbal: None significant
Food: None Known
 cholinergic stimulation of
the iris and ciliary bodies.
Generic/Brand Dose Strength & Indication/ Mechanism of Adverse/Side Effects & Nursing Rationale Client Teaching Evaluation
Name & Drug Formulation Drug Action Drug Interaction Responsibilities
Classification
Anticholinergic Indication: Commonly Observed Side - Administer - To avoid GI Educating patients upon - track the
1. 25-, 50-mg Effects: antihistamin distress taking antihistamines: patient's
Generic Name: tablet - Rhinitis e with food response to
Adult: 25-50 mg - Allergy symptoms - Drowsiness - To avoid GI distress, the
Diphenhydramin q4-6h - Motion sickness - Dizziness - If possible, - To decrease take the medication medication
e - Parkinson’s - Stomach upset increase the thickened with meals or (relief of the
2. 12.5 mg/5 disease - Constipation patient's secretions between meals. symptoms of
Brand Name: ml syrup - Dry hydration allergic
Adult 6-12 yr: 12.5- mouth/Nose/throa intake, or - Refrain from exposing rhinitis).
Benadryl 25 mg q4-6h Drug Action: t add humidity caffeine, nicotine, and
- Headache to the air alcohol. - Observe for
Classification: Formulations: Competes for H1 with - Anorexia negative
Oral: histamine - Encourage - To lower the impacts (skin
Antihistamine - Tablet and GI, bronchial, and other Adverse Reactions: the patient risk of urinary - To treat dry mouth, dryness, GI
capsules smooth muscle receptor to void retention if use warm water upset,
(25 mg and locations CNS: fatigue, nausea, modified as a rinses, synthetic sedation and
50 mg.) gastrointestinal tract, headache, problem saliva, ice chips, drowsiness,
- Chewable uterus, and significant stimulation that is sugarless gum, or urinary
tablets blood arteries, securing paradoxical (particularly in candies. retention,
(12.5 mg.) the cellular receptors and children) thickened
- Elixir, preventing - Take the pill 30 secretions,
syrup, and access and subsequent CV: hypotension, minutes prior to glaucoma).
oral histamine activity. palpitations, tachycardia travel if you're using it
solution to avoid motion - Identify the
(12.5 Interferes with histamine's GI: constipation, dry sickness. drug, dosage,
mg/5Ml) capacity to promote mouth, and diarrhea side effects to
capillary permeability and - Until the patient is look for, how
resulting edema and EENT: blurred vision, aware of how the to specifically
reduces the flare-up and tinnitus medicine affects prevent
itching brought on by the attention and them, and
endogenous release of GU: urinary frequency, alertness, advise him steps to take
histamine dysuria, or retention to refrain from driving to increase
(does not directly change and other risky the drug's
or stop the release of SKIN: photosensitivity activities. effectiveness.
histamine) The patient
Drug Interaction: can then rate
- Antihistamines the
might prevent or effectiveness
undo epinephrine's of the
vasopressor teaching plan.
effects, causing
vasodilation, an - Track the
accelerated success of the
heartbeat, and comfort and
dangerously low safety
blood pressure. precautions
- Antihistamines may as well as
cover up harmful adherence to
ototoxicity the schedule.
symptoms and
indications of
detrimental effect
of hearing brought
on by salicylates or
aminoglycosides in
high doses
- Antihistamines may
intensify the
respiratory and
sedative effects of
CNS depressants
like alcohol and
tranquilizers.
 - When used with
itraconazole,
fluconazole,
ketoconazole, or
macrolide
antibiotics (such as
erythromycin),
loratadine may
have substantial
adverse effects on
the heart.

Generic/Brand Dose Strength & Indication/ Mechanism of Adverse/Side Effects & Nursing Rationale Client Teaching Evaluation
Name & Drug Formulation Drug Action Drug Interaction Responsibilities
Classification
Proton pump Dose Strength: Indications: Adverse reactions: - Administer the - Omeprazole's - Tell the patient - Patient shows
inhibitors - GERD The following are the drug 30 absorption into or the SO to be good
- Capsules - Zollinger-Ellison commonly observed minutes or 1 the bloodstream mindful that this therapeutic
Generic Name: (delayed- syndrome adverse reactions for hour before is decreased medication response
Omeprazole release): 10 mg, - Duodenal ulcer proton pump inhibitors: meal when it is taken should be
20 mg, 40 mg - Gastric ulcer - Flatulence with food. administered 30 - Patient stays
Brand Name: - Powder for oral - H. pylori infection - Abdominal pain or 60 minutes well-hydrated
Omepron suspension - Diarrhea before meal throughout
(delayedrelease): Drug Action: - Nausea and - Inform the - To ensure the preferable every treatment.
Drug 2.5 mg, 10 mg in Blocks the production of vomiting patient not to medication's morning
Classification packets stomach acid by inhibiting open or crush therapeutic - The patient
- Tablets (delayed- the function of the acid Drug Interaction: the capsules, efficacy, they - Tell the patient and their
Pharmacologic release): 20 mg (proton) pump by binding but rather to must be taken not to chew or family or
class: to hydrogen, potassium, Warfarin, phenytoin, and drink them whole. crush the guardians
Proton pump Drug Formulation: and adenosine diazepam's metabolism whole. capsules or pills; show that the
inhibitor - Powder for oral triphosphate at the may be affected by proton instead, to drink are
Therapeutic suspension secretory surface of the pump inhibitors, - Check the level them whole. knowledgeab
class: - Tablets gastric parietal cells. lengthening their half- of magnesium  - As this increases Inform him that about drug
Antiulcer drug - Capsule lives and elevating their for those who toxicity and may if he is unable to therapy.
plasma concentrations. are anticipated cause swallow the
to be receiving hypomagnesemia capsule, he may
long-term open it and
treatment or carefully mix the
who combine entire contents
proton pump into 1
inhibitors with tablespoon of
other cool applesauce,
medications immediately
like digoxin. followed by a
glass of water.
- Provide proper
assistance to - Encourage and - Instruct the
the patient assist the patient patient how to
as they deal with use delayed-
their illness and release oral
medication suspensions.
schedule.
- Give
instructions to - Give the patient - Do not use OTC
the patient full instruction, products, other
and the SO covering the prescription
drug's name and medications, or
recommended natural therapies
dosage, the without
necessity of consulting a
taking the doctor first.
medication
whole without
opening,
chewing, or
crushing it, as
 well as the
warning signs
and symptoms of
any potential
side effects and
ways to reduce
or prevent them.
Generic/Brand Dose Strength & Indication/ Mechanism of Adverse/Side Effects & Nursing Rationale Client Teaching Evaluation
Name & Drug Formulation Drug Action Drug Interaction Responsibilities
Classification
Proton pump Availability: Indications: Adverse Effects: - Plan a dose - To avoid serious - Inform the - With
inhibitors Gelcaps: 10 mg - GERD Adverse effects are reduction if toxicity patient that a medication
Oral suspension: 40 - Zollinger-Ellison possible when using H2 the patient has medicine works therapy, the
Generic Name: mg/5 ml syndrome receptor antagonists, kidney or liver best when taken patient finds a
Famotidine Solution for injection: 10 - Duodenal ulcer particularly in older dysfunction. at night. reduction in o
mg/ml, 20 mg/50 ml of - Gastric ulcer patients or those with remission from
Brand Name: normal saline solution - Heartburn impaired renal or hepatic - Check the - Since the kidneys - Let the patient upper GI
Pepcid Tablets: 10 mg, 20 mg, function: patient for GI play a significant know that pain symptoms.
40 mg Drug Action: signs role in the relief could not - The patient
Drug Tablets (chewable): 10 - Blocks the action - Few side effects and symptoms. excretion of start for a few keeps a
Classification mg of histamine at H2 are seen with famotidine, it days after regular
Therapeutic Tablets (orally gastrointestinal famotidine and may be helpful therapy begins. heartbeat.
class: disintegrating): 20 mg, parietal cells' nizatidine, with for medical - Evaluate the
Antiulcer drug 40 mg receptors headache being professionals to - Give the patient patient's
- Regardless of the the most keep an eye on the medication's relatives or
Pharmacological Formulations: stimulating common, most renal function, dosage caregiver’s
class: - Available as substance frequent, particularly in instructions response show
Histamine2- tablets and as an (histamine, meal, followed by rash, elderly follow directions that they
receptor oral suspension insulin, caffeine, diarrhea or individuals. precisely, to comprehend
antagonist betazole, or constipation. report any drug therapy.
pentagastrin) or - Agranulocytosis, - Provide - Encourage and cardiovascular
baseline pancytopenia, support to the support patients symptoms
conditions, thrombocytopeni patient as they deal with convulsions, and
decreases a occurs rarely. their illness and alterations to
 stomach acid medication the hematology
output and Side Effects: schedule. or respiratory
concentration. - Headaches, systems
dizziness, - If CNS - To avoid injury
diarrhea, symptoms - Avoid smoking
constipation, arise, take during therapy
abdominal pain, appropriate because it
tinnitus safety and encourages the
comfort production of
Drug Interaction: measures. stomach acid
Antacids and other and makes the
medications may interact - Monitor the - These have only condition worse.
with H2 receptor patient’s very rarely been
antagonists: presence of observed in - Do not use
prolonged QT patients with additional
- Cimetidine, interval and compromised medications,
nizatidine, signs of renal function, OTC items, or
ranitidine, and seizures. and it's possible herbal therapies
famotidine's that the without first
absorption is famotidine speaking with a
decreased by dosage or dosing either the
antacids. interval wasn't physician or a
- Drug-diagnostic adjusted pharmacist.
tests. Liver properly.
enzymes: altered
levels

Generic/Brand Dose Strength & Indication/ Mechanism Adverse/Side Effects & Nursing Responsibilities Rationale Client Teaching Evaluation
Name & Drug Formulation of Drug Action Drug Interaction
Classification
H2 Blockers Dose: Indications: Adverse Reactions: - Assess the - These - Take the drug - Patient
150 mg orally 2 times a Therapy for stomach and patient’s vital assessments with a food if experiences
Generic Name: day before meal or 300 duodenal ulcers, CNS: headache, malaise, signs including, will serve as the desired. decrease in o
Ranitidine mg orally once a day particularly those caused vertigo history of baseline data relief from
before meal by H. pylori, post- EENT: blurred vision allegories and and guide as to - If you also take upper GI
Brand Name: operative ulcers brought Hepatic: jaundice hepatic and when the an antacid, follow symptoms
Zantac on by NSAIDs, acute Other: anaphylaxis, renal functions medication will the directions on with drug
Raxide reflux esophagitis, angioedema, burning and be subject for the bottle exactly therapy.
Drug Capsules (liquid-filled): Zollinger-Ellison itching at injection site adjustment of and pay attention
Classification 150 mg, 300 mg syndrome, persistent dosage or to the times of - Patient and
Pharmacologic Solution for injection: 25 episodic dyspepsia, Side Effects: monitor administration. family or
class: mg/ml in 2-, 6-, and 40-ml symptomatic treatment Blurred vision, possible toxicity caregiver
Histamine2 vials for gastroesophageal constipation, nausea, - Regularly monitor demonstrate
receptor Solution for injection reflux disease, and abdominal pain - Provide the - To guarantee your patients' an
antagonist (pre-mixed): 50 mg/50 ml prophylaxis for medication at therapeutic health to understandin
Therapeutic in 0.45% Mendelson's syndrome Drug Interaction: bedtime, before levels when the determine how of drug
Class: sodium chloride Syrup: 15 Drug-drug. or with meals medication is they are therapy
Antiulcer drug mg/ml Drug Action: Antacids: reduced (exact timing most required. responding to the
Tablets: 150 mg, 300 mg Reduces stomach acid absorption of ranitidine varies with treatments.
Tablets (effervescent): 150 output by competitively Propantheline: delayed product)
mg inhibiting histamine's absorption of ranitidine - Clearly emphasize
effect on the H2 receptor and elevated peak blood - Plan a dose - To reduce to the patient to
Raxide: sites of parietal cells. level reduction if the toxicity refrain from
Each tablet contains: Drug-diagnostic tests. client is having smoking during
Ranitidine (as Creatinine: slight kidney or liver therapy because
hydrochloride), USP 150 elevation dysfunction. it encourages the
mg or 300 mg. - A rise in hepatic production of
T: 75 mg, 150 mg, 300 mg enzyme levels - Provide - Stress the need stomach acid and
C: 150 mg, 300 mg - Smoking information for appropriate makes the
Syrup: 15 mg/ml decreases regarding the administration condition worse.
I: 25 mg/ml ranitidine medication spacing per
effeciency towards the prescription; - Instruct the
- Treatment of DU: patient stress the patient to report
300 mg/day importance of immediately if
- Maintenance of having easy there are forms
DU: 150 mg/day access to the of side effects
 - Treatment of GU: bathroom; and occur such as
300 mg/day discuss the signs diarrhea (ask for
- GERD: 300 mg/day and symptoms health care
Hypersecretory: of adverse provider to aid), if
0.3–6 g/day effects and nausea and
Forms: ways to reduce vomiting instruct
- Regular tablet or prevent the patient to
- Effervescent them. take drug with
tablet meals, for
- Capsule headaches
- Syrup - Provide antacid - To alleviate (develop a well-
- Injectable form as prescribed by pain, the lighted and
the attending interval of time temperature as
physician, be is important well as avoid
mindful that it since antacids noise).
should be can decrease
administered 1 drug
hour before or absorption.
after H2
receptor
antagonist.

Resources:

Saunder’s Nursing Drug Handbook (2016)

Lippincott’s, Drugs to know for the NCLEX-RN

Nurse’s Drug Handbook(McGraw-Hill) Seventh Edition

bakaramraju1 Follow. (n.d.). Ranitidine Drug. Share and Discover Knowledge on SlideShare. Retrieved September 25, 2022, from
https://www.slideshare.net/bakaramraju1/ranitidine-drug

Famotidine. Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). Retrieved September 25, 2022, from https://go.drugbank.com/drugs/DB00927
Marianne Belleza, R. N. (2022, May 3). Antihistamines Nursing Pharmacology Study Guide. Nurseslabs. Retrieved September 25, 2022, from
https://nurseslabs.com/antihistamines/