Automated Clinical Chemistry Analyzer

JAPAN QUALITY
 Compact & Easy Operability & Excellent Function
Improved user-friendly interface and test efficiency
The latest model of TMS series meeting various needs of clinical laboratory tests

HbA1c Measurement Directly Brand new user interface

from Whole Blood

• Intuitive screen layout with a sense of unity
• Item parameter in one screen relieving the bother of page feeding

Upgraded operability
• Various touch panel operation (swipe-to-select / drag & drop ) contributing to
better facility of operation
• Enlarged buttons for reducing operation errors

Upgraded throughput
• 270 tests/hour (maximum 450 tests/hour with ISE )

Auto hemolysis of whole blood sample for HbA1c

• Automatic process on board contributing to the test efficiency and accuracy

Automatic sample clot detection

• Automatic detection & clean-up of sample probe clots (such as !brin)

Crash prevention
• Prevent reagent & sample probes from crash during operation for safety

Automatic startup and shutdown

• Stress-free operation by cutting waiting time

Ethernet connections
• Ethernet connections between machine and operation PC for higher-speed and
more stable communication

1 2
 Compact & Easy Operability & Excellent Function
Improved user-friendly interface and test efficiency
The latest model of TMS series meeting various needs of clinical laboratory tests

HbA1c Measurement Directly Brand new user interface

from Whole Blood

• Intuitive screen layout with a sense of unity
• Item parameter in one screen relieving the bother of page feeding

Upgraded operability
• Various touch panel operation (swipe-to-select / drag & drop ) contributing to
better facility of operation
• Enlarged buttons for reducing operation errors

Upgraded throughput
• 270 tests/hour (maximum 450 tests/hour with ISE )

Auto hemolysis of whole blood sample for HbA1c

• Automatic process on board contributing to the test efficiency and accuracy

Automatic sample clot detection

• Automatic detection & clean-up of sample probe clots (such as fibrin)

Crash prevention
• Prevent reagent & sample probes from crash during operation for safety

Automatic startup and shutdown

• Stress-free operation by cutting waiting time

Ethernet connections
• Ethernet connections between machine and operation PC for higher-speed and
more stable communication

1 2
 Main unit arrangement Specifications
Cuvette washing system System Discrete single line random access multi-test analysis
Number of test items on board 36+3 (ISE)
Reaction tray Analysis Throughput 270 tests/hour, 450 tests/hour including ISE, 90tests/hour for HbA1c only
Analysis method End point, Rate, ISE
Lamp (Easy replacement） Sample probe Calibration curve 8 kinds (linear , spline, etc)
Sample kind Serum, Plasma, Blood cell, Urine, Dialisys, CSF (ISE not available for CSF and Blood cell)
Sample container Sample cups, primary tube (5, 7, 10ml)
Number of samples on Software tray (30 positions for primary sample, and 45 positions for standard and blank sample)
board
Sample Sample tray mode
Selectable modes for patient sample, calibration an d QC
(software tray)
Sample dispensing volume 2.0 ～ 25.0 μL（0.1 μL step）
Dilution ratio 0.5 〜 100 times
STAT Available during measurement (step between samples by priority)
Reagent tray 36 items (removable)
Number of bottles on board 72 (36 items)
Bottle size 36 items : 13, 25, 40 ml
ISE sample Reagent 24 items : 20, 40, 60 ml
inlet Reagent dispensing volume R1 : 140～ 300μL (1 μL step）, R2 : 20 ～ 260 μL (1μL step）
Reagent storage 24 hours cooling
Reagent volume check Level sensing or count down
Cuvette material Plastics (semi-disposable)
Reaction volume 140 ～ 400μL
Reaction time approx 10 min. (1st reaction 5 min., 2nd reaction 5min.)
Reaction temperature 37 ± 0.10 C
Optical measurements Fixe d 1 3 w a ve le ng t h s（3 4 0 〜 8 0 0 n m )
Reaction Optical source Tungsten halogen lamp
Optical range OD 0.0 ～ 2.5
Cuvette washing Auto washing with heated water and 2 kinds of washing solutions
Reaction waste collection Reaction waste stored in a dedicated tank
Pure water consumption Maximum 3.8 L /hour
Operation Personal computer
OS Windows 10
Interface Reaction monitor Optical absorbance graphic display
Reagent probe Quality control Current, Daily and Cumulative QC. Westgard algorithms
Individual probes are used Output Ethernet connection
Reagent tray
for 1st and 2nd reagents to Sample tray ISE module
36-item tray Option
avoid carry-over 45 Positions Sample barcode reader, Reagent barcode reader
Specifications are subject to change without notice .

Installation Test Items List

Conditions The space required for installation LD(LDH) AST(GOT) ALT(GPT) ALP γ-GTP CK(CPK) CK-MB
unit:mm ChE AMY P-AMY* LAP CRE UA BUN
Item Description Cys-C TG T-CHO HDL-C LDL-C TP ALB
320 Clinical
IP Mg Ca Fe TIBC Zn Cu
Dimensions and Analyzer chemistry
GLU HbA1c 1,5-AG* GA* μTP μALB
Weight W800 × D670 × H555 (mm) Approx. 95Kg IRI
L-FABP* T-BIL D-BIL TTT* ZTT* NH3* NEFA*
AC 100/115/220/230V、50/60Hz PL * SIA * Fer
Power supply 670 Analyzer
Voltage fluctuation less than 10%
Cougulation* AT FDP D-dimer
Power consumption 600VA
Earth resistance of ground terminal should be CRP RF TPAb* RPR * IgG IgA IgM
Grounding Immuno-assay
less than 100Ω IgE MMP-3*
500 800 500
Ambient temperature 15~300C VCM TPM MTX BRP
ABK EVER TACR
Humidity 45~85% (No condensation) 1800 TDM* PHT
CBZ DIG HAL PB THEO VPA
Water consumption Max 3.8 l / hour
Waste liquid Separate drainage (low and high density waste) ISE Na K Cl

At least 1000mm upper space required. * Above includes test items under verification.

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 Main unit arrangement Specifications
Cuvette washing system System Discrete single line random access multi-test analysis
Number of test items on board 36+3 (ISE)
Reaction tray Analysis Throughput 270 tests/hour, 450 tests/hour including ISE, 90tests/hour for HbA1c only
Analysis method End point, Rate, ISE
Lamp (Easy replacemen）
t Sample probe Calibration curve 8 kinds (linear , spline, etc)
Sample kind Serum, Plasma, Blood cell, Urine, Dialisys, CSF (ISE not available for CSF and Blood cell)
Sample container Sample cups, primary tube (5, 7, 10ml)
Number of samples on Software tray (30 positions for primary sample, and 45 positions for standard and blank sample)
board
Sample Sample tray mode
Selectable modes for patient sample, calibration and QC
(software tray)
Sample dispensing volume 2.0 ～ 25.0 μL（0.1 μL step）
Dilution ratio 0.5 〜 100 times
STAT Available during measurement (step between samples by priority)
Reagent tray 36 items (removable)
Number of bottles on board 72 (36 items)
Bottle size 36 items : 13, 25, 40 ml
ISE sample Reagent 24 items : 20, 40, 60 ml
inlet Reagent dispensing volume R1 : 140～ 300μL (1 μL step）, R2 : 20 ～ 260 μL (1μL step）
Reagent storage 24 hours cooling
Reagent volume check Level sensing or count down
Cuvette material Plastics (semi-disposable)
Reaction volume 140 ～ 400μL
Reaction time approx 10 min. (1st reaction 5 min., 2nd reaction 5min.)
Reaction temperature 37 ± 0.10 C
Optical measurements Fixe d 1 3 w a ve le ng t h s（3 4 0 〜 8 0 0 n m )
Reaction Optical source Tungsten halogen lamp
Optical range OD 0.0 ～ 2.5
Cuvette washing Auto washing with heated water and 2 kinds of washing solutions
Reaction waste collection Reaction waste stored in a dedicated tank
Pure water consumption 3.5L/Hour (maximum 3.8L/Hour on HbA1c with RBC Cells)
Operation Personal computer
OS Windows 10
Interface Reaction monitor Optical absorbance graphic display
Reagent probe Quality control Current, Daily and Cumulative QC. Westgard algorithms
Individual probes are used Output Ethernet connection
Reagent tray
for 1st and 2nd reagents to Sample tray ISE module
36-item tray Option
avoid carry-over 45 Positions Sample barcode reader, Reagent barcode reader
Specifications are subject to change without notice .

Installation Test Items List

Conditions The space required for installation ALBUMIN
ALKALINE PHOSPHATASE-
ALKALINE PHOSPHATASE-IFCC AMYLASE BILIRUBIN DIRECT
DGKC
unit:mm
BILIRUBIN TOTAL TAB CALCIUM (ARSENAZO) CHLORIDE CHOLESTEROL CREATININE
Item Description Clinical CK-NAC CREATININE Modified Jaffe CREATININE ENZYMATIC GAMMA GT GLUCOSE-GOD POD
320 Chemistry GLUCOSE HEXOKINASE HDL – C DIRECT LDH – P LDL – C DIRECT MAGNESIUM
Dimensions and Analyzer INORGANIC PHOSPHOROUS SGOT SGPT TOTAL PROTEIN TRYGLYCERIDES
UREA UV URIC ACID
Weight W800 × D670 × H555 (mm) Approx. 95Kg Apo A1 Apo B ASO C3 C4
CERULOPLASMIN CRP CRP ULTRA CYSTATIN C FERRITIN
AC 100/115/220/230V、50/60Hz Immuno Assy
Analyzer HbA1c DIRECT IgA IgE IgG IgM
Power supply 670
Voltage fluctuation less than 10% Lp(a) MICROALBUMIN RF TRANSFERRIN
ADENOSINE DEAMINASE CHOLINESTERASE CK-MB D-DIMER IRON
Power consumption 600VA Up Coming
LIPASE MICROPROTEIN TIBC ZINC ALPHA 1 ACID GLYCO PROTEIN
Earth resistance of ground terminal should be Parameters ALPHA 1 ANTITRYPSIN FERRITIN HAPTOGLOBIN PREALBUMIN
Grounding
less than 100Ω
500 800 500
Ambient temperature 15~300C
Humidity 45~85% (No condensation) 1800
Water consumption Max 3.8 l / hour
Waste liquid Separate drainage (low and high density waste)

At least 1000mm upper space required.

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 Our original system for mixing the sample
User Interface Air pressure mixing system and reagent using air pressure alone.

DOWN PRESSURE SUCTION UP

Run monitor screen Journal screen

AIR

SAMPLE
Reaction cuvette
• Specially developed to
utilize air pressure mixing
system
• The material is water
REAGENT REPEAT
repellent plastic
(Semi-disposable)
Advantages of Air Pressure Mixing
Monitor measurement info by cycles View sample ordered time and result out-put time
• No carry-over because a stirrer is not used
• No water consumption for stirrer washing
• No dilution of the reaction solution by washing water from the stirrer

Order screen QC graph screen

HbA1c sample preparation and measurement
Centrifuged Cuvette1 Cuvette2
sample

Aspirating HbA1c(%) is calculated

the red from hemoglobin and
blood cell. A1c results.

Easy to select test items by swiping the touch scre en Current,daily,and cumulative QC Dispensing the red blood cell Hemoglobin (Hb) is measured by R1.
into the hemolyzing reagent A1c is measured by R2.
and mixing them. In the case of Enzymatic method

Auto startup & shutdown screen Result screen

ISE module (OPTION)

Side view

Auto maintenance available before shutdown Show current day test results
ISE is Direct Method Consumables for ISE module
(Separate printer needed for output)
Throughput is 450 tests/hour including ISE Calibrators
ISE module is equipped with Biolis 30i Cleaning solution
Easy to replace electrodes Electrode (Na, K, Cl, Ref)

5 6
 Our original system for mixing the sample
User Interface Air pressure mixing system and reagent using air pressure alone.

DOWN PRESSURE SUCTION UP

Run monitor screen Journal screen

AIR

SAMPLE
Reaction cuvette
• Specially developed to
utilize air pressure mixing
system
• The material is water
REAGENT REPEAT
repellent plastic
(Semi-disposable)
Advantages of Air Pressure Mixing
Monitor measurement info by cycles View sample ordered time and result out-put time
• No carry-over because a stirrer is not used
• No water consumption for stirrer washing
• No dilution of the reaction solution by washing water from the stirrer

Order screen QC graph screen

HbA1c sample preparation and measurement
Centrifuged Cuvette1 Cuvette2
sample

Aspirating HbA1c(%) is calculated

the red from hemoglobin and
blood cell. A1c results.

Easy to select test items by swiping the touch scre en Current,daily,and cumulative QC Dispensing the red blood cell Hemoglobin (Hb) is measured by R1.
into the hemolyzing reagent A1c is measured by R2.
and mixing them. In the case of Enzymatic method

Auto startup & shutdown screen Result screen

ISE module (OPTION)

Side view

Auto maintenance available before shutdown Show current day test results
ISE is Direct Method Consumables for ISE module
(Separate printer needed for output)
Throughput is 450 tests/hour including ISE Calibrators
ISE module is equipped with Biolis 30i Cleaning solution
Easy to replace electrodes Electrode (Na, K, Cl, Ref)

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 C US

Headquarters & R&D Center

1-14-21, Higashitoyoda, Hino, Tokyo, 191-0052 Japan
Tel: +81-42-587-7777 Fax: +81-42-587-7781
URL http://www.tb-medisys.co.jp/english/
Marketed by,
AGAPPE DIAGNOSTICS LIMITED, “Agappe Hills”, Pattimattom (PO), Dist.
Ernakulam, Kerala - 683 562, India. ISO 9001 : 2015
EN ISO 13485 : 2016
TEL: + 91 484 2867000 | FAX: +91 484 2867222 | agappe@agappe.in | www.agappe.com

* Toll Free No: 1800 425 7151 Ver.2.00 18. November