BRAND STORY

By combining "Hya" of hyaluronic acid, "Fill" of filling, and suffix "ia",

CHA MEDITECH has created the utmost HA Dermal Filler brand, HYAFILIA.

HyaFilia collected only the best parts of other former HA Fillers

and upgraded them into a New Generation Hyaluronic Acid Filler.
HyaFilia is the result of ceaseless research for more facial volume
and natural V-Line.

TECHNOLOGY

BI MONO

-Phasic

V-Phasic technology enables HyaFilia to

possess only the best values of bi-phasic and
mono-phasic fillers. As a result, HyaFilia
has superior cohesiveness and elasticity at
the same time while also maintaining low
injection force.

LONG
SMOOTH SAFE NATURAL ELASTIC
LASTING
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1. MORE SAFE

1 Unique Manufacturing Process

: Using a Magnetic and Air Centrifugal Mixer

Revolution

Rotation

2 Result of BDDE Usage

R J SMVI

BDDE Usage (mol%) 4 18 3.5

Minimize input of BDDE chemically,

Strongly combine Hyaluronic Acid physically

1,4-butanediol diglycidyl ether (BDDE) is reported to

be able to cause an allergic reaction due to its toxicity.
Safety is reported to possiblity cause .
2. MORE ELASTIC

1 A Measure of Elastic Modulus (G’) by Rheometer

450

350

250

150

50

0
R J

Higher Elastic Modulus , Stronger to External Force

2 Ability Test to External Force

Existing Product HyaFilia SMVI

To verify the ability to withstand external forces, place a glass on the gel
and observe the shape of the gel after 1 hour.

Elastic modulus is a force of resistance to an external force.

Higher elastic modulus of substance allows stronger force to deform
a shape or to lift the skin.
 3. MORE LONG-LASTING

1 Test for Enzyme Decomposition 2 Gel Tendency After Treatment of

Hyaluronidase

Enzyme decomposition Before Before

characteristic (%)

100

50

After
0 2 Hours
0 1 8 16 24
After After
J R SMVI

R J SMVI
Control HyaFilia SMVI
Maintain properties (%) 7.7 0.3 10.9

Maintain properties (%) after 24 hours Treatment of Hyaluronidase to observe the

of hydrolysis treatment tendency of gel to be degraded (After 2 hours)

Crosslinked HA, manufactured with its own specialized technology, has long-lasting
effects due to its excellent enzyme resistance to slow decomposition in the body
despite a small amount of BDDE.
4. MORE NATURAL
1 Measure of Cohesion (Tack Value)
Tack
0.6

0.3

0
R J

R J SMVI

Tack 0.3981 0.4365 0.6023

The higher the tack value, the higher the cohesion
Higher cohesion than existing biphasic and monophasic

2 Comparison of Gel Adhesion

Existing Product HyaFilia SMVI

High cohesion enables the treatment to be performed in the desired shape,

resulting in a natural look and prevents migration after the treatment.
5. MORE SMOOTH

1 Measure of Injection Force

Injection Force (N)

20

10

0
R J

Proportional injection force with cohesiveness

Lower injection force than existing monophasic fillers

Injection Force
measurement

“Smooth” injection allows doctors to control procedures easily and

it is possible to perform a procedure delicately.
Doctors can minimize patients' skin damage, prevent bruising, erythema
and edema after the procedures.
 Non-Lidocaine

HyaFilia S HyaFilia M HyaFilia V HyaFilia I

Cross-linked HA Cross-linked HA Cross-linked HA Cross-linked HA

Composition
(20mg/ml) (20mg/ml) (20mg/ml) (20mg/ml)

Filling of all moderately Filling of all moderately

Correction of Filling
Indications superficial wrinkles pronounced wrinkles pronounced wrinkles
deep wrinkles
on the full face on the full face

Deep Dermis or
Injection Area Superficial Dermis Mid-Dermis Mid-Dermis
Subcutaneous Tissue

Needle Size 27G / 30G 27G / 30G 25G / 27G Not Included

Packing Unit 1ml 1ml 1ml 5ml

 Lidocaine Skin
Booster

HyaFilia S HyaFilia M HyaFilia V HyaFilia HyaFilia

Plus Plus Plus Impact Dorothy

Cross-linked HA Cross-linked HA Cross-linked HA Cross-linked HA Cross-linked HA

Composition (20mg/ml) (20mg/ml) (20mg/ml) (20mg/ml) (15mg/ml)

Filling of all
Immediate
Correction of moderately Filling Body contouring &
Indications skin rejuvenating
superficial wrinkles pronounced wrinkles deep wrinkles Penile enlargement
& Skin glowing
on the full face

Superficial Deep Dermis or

Injection Area Mid-Dermis Body & Penis Superficial Dermis
Dermis Subcutaneous Tissue

Needle Size 27G / 30G 27G / 29G 25G / 27G Not Included Not Included

Packing Unit 1ml 1ml 1ml 10ml 3ml x 3ea