CLR  Product Overview

APPLICATION CERTIFICATION
CLR PRODUCT GROUPS
ANTI-AGING 4–8

BARRIER MAINTENANCE AND

MOISTURIZERS 9–11

HAIR CONDITIONING AND

ANTI-WRINKLE, FIRMING,

SOOTHING, CALMING,
SENSITIVE & OILY SKIN 12–15

SKIN REGENERATION

CHINA COMPLIANT
BARRIER MAINTENANCE AND REPAIR 16–17

SKIN PROTECTION

SKIN LIGHTENING

ANTI– HAIR LOSS
MOISTURIZING
HAIR CARE 18–19

QUASI DRUG
SMOOTHING

ANTI-STRESS

SOLUBILITY
PROTECTION
ANTI-ACNE

HALAL
REPAIR
PRODUCT NAME PAGE

AnnonaSense CLR™ 12  C ws
Arnica Oil CLR 15   Q C H os
Belides ™ ORG 6  Q C H ws

Calendula Oil CLR 14  C H os

Carrot Oil CLR 7  Q C os

Ceramide Complex CLR™ K 10    Q C ws

Collagen CLR 11  C ws

Cutipure CLR™ 14  C ws

DayMoist CLR™ 9, 19   C ws

Elastin CLR 11  Q C ws

Follicusan™ DP 18  C ws

Glycoderm™ (P) 10   C ws

Hexaplant™ Richter 15   C ws

Hygroplex™ HHG 10   Q C H ws

JuvenEye CLR™ 5   C ws
H)
Lactokine™ Fluid PF 7, 13     C ws

Maricol S 11  C H ws

ws: water-soluble
Modukine™ 13, 17    Q C ws

MPC™-Milk Peptide Complex 5   Q C H ws

MultiMoist CLR™ 9, 18   C ws

PhytoDefense CLR™ 13  C os

Phytosan™ K 5    Q C H ws

wd: water-dispersible
ProBarrier™ CLR 7  C wd

ProBioBalance CLR™ NP 14   Q C ws

ProRenew Complex CLR™ 4, 16    C ws

Repair Complex CLR™ PF 6  Q C ws

Sedaplant™ Richter 15   C ws

Soluvit Richter NP 8   C ws

St. John‘s Wort Oil CLR 15  C os

os: oil-soluble

SyriCalm™ CLR (PC) 12, 17   C H ws

Vitamin F forte 17, 19    C H os

Wheat Germ Oil CLR 8   C os

Alternative preservation systems For information on natural certifications, such as COSMOS and NATRUE (1), see:
are available for some products. https://www.clr-berlin.com//products.
H: HALAL-certified (1) H)
 : Also available in Halal quality (1)
Application Q: Can be used in Japan as a (non)-functional ingredient in Quasi Drugs
 tested  recommended C: Ingredients listed in IECIC-list (Inventory of Existing Cosmetic Ingredients in China)
(1) For current certification validities please see https://www.clr-berlin.com/category/certifications/

2
Efficient actives and concepts for cosmetics

CLR – Chemisches Laboratorium Dr. Kurt Richter GmbH –

develops innovative and high-quality cosmetic actives for
skin and hair care.

In the early 1950s CLR began to focus on the manufacture

of biologically active cosmetic ingredients. Over the past 60
years, CLR has enriched beauty and personal care with
many novel actives and pioneering concepts.

Specializing in the development of biologically active

products, we use state-of-the art methods and technology
to ensure high-quality performance and create a stable
foundation for future improvements. We constantly review
our quality management system to match current require-
ments. Consequently we have intro­duced an integrated
management system combining quality, environmental and
social responsibility aspects in accordance with ISO 9001,
ISO 14001, SA8000 and EFfCI GMP standards.

It is our mission to supply the cosmetics industry with high-

quality actives; we have a focus on the development of new
products with scientifically proven effects and innovative
concepts for their use. In cooperation with our customers
we actively and efficiently work out creative, tailor-made
cosmetic concepts that match their specific requirements.

3
 ProRenew Complex CLR™
ANTI-AGING

Probiotic approach to skin renewal and resurfacing

in vivo ex vivo in vitro

ProRenew Complex CLR™   skin  

Based on probiotic technology, ProRenew Complex CLR™ Dosage: 3.0%

acts on essential features in the aging process of the skin, pH range: 4.0–7.0
its ability to successfully adapt to a constantly changing
environment and to effectively renew itself. INCI Name:
Lactococcus Ferment Lysate
ProRenew Complex CLR™ positively influences the speed
and quality of epidermal growth. It has shown to effectively ProRenew Complex CLR™
promote desquamation, the shedding of dead cells. is preserved with sodium benzoate.
ProRenew Complex CLR™ is beneficial for both the health of
skin and the skin microbiota. It balances and protects the Also available as
Application skin microbiota and supports it in dealing with day-to-day ProRenew Complex CLR™ NP,
 skin regeneration stress. stabilized with phenylpropanol and
 barrier maintenance levulinic acid/sodium levulinate.
and repair
 skin protection

4
 in vivo ex vivo in vitro
MPC ™ – Milk Peptide Complex   skin  

MPC™ reduces the visible signs of aging by reactivating skin Dosage: 0.5%
cells and inducing the production of extracellular matrix pH range: 6.0–7.0
molecules in the dermis, such as collagen Type I, hyaluronic
acid and fibronectin. In vivo studies have shown that formu- INCI Name: Whey Protein
lations with MPC™ make the skin firmer and improve its
elasticity. MPC™ quickly and effectively reduces wrinkle MPC™– Milk Peptide Complex
depth and improves the structure of the skin. is unpreserved.

MPC™–Milk Peptide Complex contains a complex of acti- MPC™-Liposomes

vated, natural signaling growth factors derived from milk, is preserved with phenoxyethanol
Application such as TGF-β. and sodium dehydroacetate.
 anti-wrinkle, firming,
smoothing Also available encapsulated in plant-derived liposomes as
 skin regeneration MPC™-Liposomes.

in vivo ex vivo in vitro

Phytosan ™ K   skin  

Phytosan™ K exerts a potent influence against skin aging. It Dosage: 2.0–5.0%

activates cellular repair processes, supporting the mainte- pH range: 3.0–7.5
nance of cellular integrity and energy after UV irradiation.
Both are important factors in counteracting photoaging. INCI Name:
Water, Glycerin, Glycine Soja (Soybean)
Phytosan™ K also has potent regenerative effects, such as Seed Extract
stimulation of collagen synthesis. This results in improved
skin firmness and smoothness and a reduction of wrinkle Phytosan™ K
depth. Phytosan™ K counteracts biological and UV-induced is preserved with phenoxyethanol
premature aging of the skin. and potassium sorbate.
Application
 anti-wrinkle, firming, Phytosan™ K contains proteins, glycoproteins and poly­sac­
smoothing charides isolated from organic soybeans (GMO-free).
 skin regeneration
 skin protection

in vivo ex vivo in vitro

JuvenEye CLR™   skin  

Based on a synergistic combination of extracts of Hieracium Dosage: 3.0–5.0%

pilosella and the flowers of Bellis perennis, JuvenEye CLR™ pH range: 4.5–6.5
addresses the most important dermatological processes in
the formation and the persistence of dark circles. It activates INCI Name:
vital processes which allow for the breakdown of heme, Bellis Perennis (Daisy) Flower
which is both dark-colored and plays an important role in the Extract, Hieracium Pilosella
etiology of dark circles. JuvenEye CLR™ also activates dermal (Hawkweed) Extract
draining through its ability to increase the production of
VEGF-C. Excess fluids, electrolytes and immune cells are JuvenEye CLR™
drained away more effectively. With JuvenEye CLR™, is preserved with sodium benzoate
Application melanin deposition in the skin is reduced and overall skin and sodium dehydroacetate.
 skin regeneration health is improved.
 skin lightening
In in vivo studies where JuvenEye CLR™ was compared with
a corresponding placebo formulation it could be seen that
JuvenEye CLR™ clearly reduces the visibility of dark circles.
Both the color and the surface area of dark circles were
reduced significantly.

5
ANTI-AGING

Repair Complex CLR ™ PF

A probiotic approach towards photoaging

in vivo ex vivo in vitro

Repair Complex CLR ™ PF   skin  

Repair Complex CLR™ PF is a biotechnological anti-aging Dosage: 5.0–10.0%

active, obtained from a lysate of probiotic bifidobacteria, pH range: 3.8–7.0
which potently protects against UV-induced damage in the
skin. UV radiation leads to skin cell damage and immunosup- INCI Name:
pression, a deactivation of the local immune system in the Bifida Ferment Lysate
skin.
Repair Complex CLR™ PF
By effectively activating anti-immunosuppressive processes is preserved with phenoxyethanol
on the cellular level, Repair Complex CLR™ PF increases and sodium benzoate.
cellular repair and potently supports the skin’s endogenous
Application protection mechanisms. Repair Complex CLR™ PF thus coun-
 skin protection teracts pre­mature skin aging, i.e. photoaging.

in vivo ex vivo in vitro

Belides ™ ORG   skin  

Belides™ ORG is a natural skin-lightening agent, derived Dosage: 2.0–5.0%

from organic daisy flowers (Bellis perennis). It is suitable for pH range: 4.5–6.5
any skincare concept providing even and luminous com-
plexion and radiant skin. INCI Name:
Bellis Perennis (Daisy) Flower Extract
Belides™ ORG’s action is based on a potent, multifaceted
reduction in the activity of melanocytes. Belides™ ORG Belides™ ORG
influences different cellular pathways involved in melano- is stabilized with phenethyl alcohol.
genesis, encompassing the reduction of cellular signaling,
tyrosinase transcription, tyrosinase activity and melanosome Also available as
Application transfer. These actions lead to even pigmentation and make Belides™ NP,
 skin lightening age spots less visible. stabilized with small amounts of
ethanol, phenethylalcohol,
glycerin and Melissa officinalis.

6
 in vivo ex vivo in vitro
Lactokine ™ Fluid PF   skin  

Lactokine™ Fluid PF is a multifunctional agent, suitable for a Dosage: 2.0–5.0%

wide variety of skincare concepts. It effectively soothes and pH range: 5.8–7.0
calms skin, accelerating the reduction of skin redness and
irritation after external stresses. Additionally, Lactokine™ INCI Name: Milk Protein
Fluid PF vitalizes and energizes skin cells and induces the
synthesis of collagen, yielding skin smoothing and firming Lactokine™ Fluid PF
properties, thus making it a potent anti-aging product. In is preserved with
other in vivo studies Lactokine™ Fluid PF was shown to be phenoxyethanol and
very effective in skin lightening, reducing the production of sodium dehydroacetate.
melanin.
Application Also available as
 anti-wrinkle, firming, Lactokine™ Fluid PF contains a network of activated and Lactokine™ Fluid PF-H
smoothing stabilized signal molecules derived from milk. Halal-certified (1)
 soothing, calming,
anti-stress
 skin lightening
 skin protection

in vivo ex vivo in vitro

ProBarrier ™ CLR   skin  

ProBarrier™ CLR, a suspension of waxy particles based on Dosage: 3.0%

caprylic/capric triglycerides and Copernicia cerifera (carnauba) pH range: 4.5–7.5
wax, is a highly technological skincare ingredient which
creates a persistent but non-occlusive film on the skin. It is INCI Name:
especially designed for cosmetic formulations which aim to Water, Caprylic/Capric Triglyceride,
shield the skin against harsh environmental conditions, Copernicia Cerifera (Carnauba) Wax,
providing an extra layer of protection and an excellent light Decyl Glucoside, Pentylene Glycol
skin feel.
ProBarrier™ CLR
is stabilized with pentylene glycol.
Application
 skin protection

in vivo ex vivo in vitro

Carrot Oil CLR   

Carrot Oil CLR is especially suitable for anti-aging skin care,

sun and after-sun care, and all skincare concepts for Dosage: 0.5–5.0%
obtaining an even and harmonious skin color. Carrots are INCI Name:
renowned for their high content of ß-carotene, which is Glycine Soja (Soybean) Oil,
further enriched in Carrot Oil CLR to obtain optimal results Daucus Carota Sativa (Carrot)
for the skin, providing skin with much needed protection. Root Extract, Beta-Carotene,
Tocopherol
Carrot Oil CLR is a lipophilic extract of Daucus carota sativa
in stabilized soybean oil, enriched with anti-oxidative ß-car- Carrot Oil CLR
otene to 3,300 IU/g. is stabilized with a natural
Application tocopherol concentrate.
 skin protection

7
 in vivo ex vivo in vitro
Wheat Germ Oil CLR   
ANTI-AGING

Wheat Germ Oil CLR is particularly suitable for skin protection Dosage: 2.0–5.0%
concepts and the care of sensitive and severely dry skin and
lips. Wheat Germ Oil has an extensive history of use. For cen- INCI Name:
turies, it has been used for a wide variety of skincare Triticum Vulgare (Wheat) Germ Oil
applications, for instance for its healing properties and for
the treatment of many different skin ailments.

Wheat Germ Oil CLR is obtained from freshly milled wheat

germs renowned for their high antioxidant content.

Application
 skin protection
 soothing, calming,
anti-stress

in vivo ex vivo in vitro

Soluvit Richter NP   

Soluvit Richter NP is suitable for a wide variety of skin and Dosage: 1.0–5.0%
haircare concepts, such as the treatment of eye bags, dark pH range: 3.0–10.0
circles, bruises and the care of tired legs and nails, but also
for anti–hair loss. INCI Name:
Water, Alcohol, PEG-35 Castor Oil,
Soluvit Richter NP is based on an extract of horse chestnut Polysorbate 20, Aesculus Hippo-
enriched with vitamins A, E, F, H (biotin) and vitamins of the castanum (Horse Chestnut) Seed
B group. Horse chestnut has a rich history of use in tradi- Extract, Retinyl Palmitate, Toco­pherol,
tional and modern medicine, especially for its stimulating Inositol, Calcium Pantothenate,
and energizing properties. The vitamins show an extensive Linoleic Acid, Biotin
Application range of potential benefits for both skin and hair.
 skin regeneration Soluvit Richter NP is unpreserved.
 anti–hair loss

8
MOISTURIZERS

MultiMoist CLR™
Mapping the moisturization puzzle

in vivo ex vivo in vitro

MultiMoist CLR™   skin   hair 

MultiMoist CLR™ activates production of the vitamin D Dosage: 3.0%

receptor (VDR) and promotes the VDR’s activation. pH range: 3.0–8.0
MultiMoist CLR™ also potentiates the effect of vitamin D. As
a consequence the skin becomes more moisturized. By INCI Name:
making use of 5 different objective instrumental approaches, Fructooligosaccharides, Beta Vulgaris
the immediate and long term moisturizing properties of (Beet) Root Extract, Water
MultiMoist CLR™ were convincingly proven. Additionally,
the activity of MultiMoist CLR™ was proven in a consumer MultiMoist CLR™
study, where the subjective improvement of skin moisture is unpreserved.
content, skin smoothness and the look of skin were
Application confirmed.
 moisturizing
 hair conditioning and MultiMoist CLR™ consists of a powerful synergistic blend of
protection fructooligosaccharides and beta vulgaris (beet) root extract.

in vivo ex vivo in vitro

DayMoist CLR ™   skin   hair 

DayMoist CLR™ potently and immediately increases the Dosage: 1.0–3.0%

concentration of the natural moisturizing factors (NMF) pH range: 3.0–10.0
in the upper layers of the skin, resulting in immediate and
long-lasting moisturizing effects. These results were INCI Name:
obtained by making use of Confocal Raman Microspectroscopy Water, Hydrolyzed Corn Starch,
and analyzing skin capacitance. Additionally, DayMoist Beta Vulgaris (Beet) Root Extract
CLR™ has potent haircare properties (see the haircare
section in this brochure). DayMoist CLR™
is stabilized with plant-derived
DayMoist CLR™ is a complex of natural plant-derived active anisic acid.
Application ingredients.
 moisturizing
 hair conditioning and
protection

9
 in vivo ex vivo in vitro
Hygroplex ™ HHG   skin   hair 
MOISTURIZERS

Hygroplex™ HHG is a physiological moisturizer, specifi­cally Dosage: Skin: 2.0–5.0%

designed to be fully adapted to the water-binding capacity Hair: 1.0%
of human skin, containing ingredients similar to the Natural pH range: 3.0–10.0
Moisturizing Factors (NMF) in the skin. It is extremely
suitable for skincare concepts for dry and aged skin and can INCI Name:
be used in any skincare application for any type of skin Hexylene Glycol, Fructose, Glucose,
which needs hydration. Hygroplex™ HHG effectively mois- Sucrose, Urea, Dextrin, Alanine,
turizes and smoothes the skin. Glutamic Acid, Aspartic Acid, Hexyl
Nicotinate
Additionally, it has shown to be a potent moisturizer for hair,
Application increasing its water content and improving its mechanical Hygroplex™ HHG is unpreserved.
 moisturizing properties.
 hair conditioning and
protection Also available as Hygroplex™ WHN without hexyl nicotinate.

in vivo ex vivo in vitro

Glycoderm ™ (P)   skin  

Glycoderm™ (P) is a liposomal moisturizer, where plant Dosage: 3.0–5.0%

derived liposomal bilayers contain biotechnologically pH range: 3.0–10.0
produced hyaluronic acid and natural blossom honey. Its
liposomal structure supports quick absorption of hyaluronic INCI Name:
acid and blossom honey. Water, Honey, Phospholipids,
Sphingolipids, Hyaluronic Acid
Consequently, Glycoderm™ (P) constitutes a polyvalent
approach toward skin hydration by supporting the mainte- Glycoderm™ (P)
nance and recovery of the skin’s lipid barrier function and is preserved with phenoxyethanol
supplying the skin with essential ingredients that are able to and sodium dehydroacetate.
Application bind water and moisturize skin.
 moisturizing
 barrier maintenance
and repair

in vivo ex vivo in vitro

Ceramide Complex CLR ™ K   

Ceramide Complex CLR™ K supplies skin with structural Dosage: 5.0–10.0%

elements and supports the recovery and maintenance of the pH range: 3.0–10.0
skin’s healthy barrier function and water-holding
capacity. INCI Name:
Water, Phospholipids, Sphingolipids
Ceramide Complex CLR™ K contains 2% lipids in lamellar
liquid crystalline form. The plant-derived lipid mixture Ceramide Complex CLR™ K
consists of phospholipids and at least 10% sphingolipids, is preserved with phenoxyethanol
and is easily able to penetrate skin. and potassium sorbate.
Ceramide Complex CLR™ K also moisturizes hair.
Application
 moisturizing
 barrier maintenance
and repair
 hair conditioning and
protection

10
 in vivo ex vivo in vitro
Collagen CLR    

Collagen CLR has strong affinity and substantivity to human Dosage: 3.0–10.0%

skin, making it a potent natural film-forming ingredient. pH range: 3.7–6.5
With its extremely high water-binding capacity, Collagen
CLR nurtures the skin instantly, effectively and noticeably. INCI Name: Soluble Collagen
Since it improves the biomechanical properties of skin, skin
feels smoother and more supple. Collagen CLR
is preserved with sodium benzoate.
Collagen CLR comprises native, soluble collagen with a
“skin-identical” triple helical structure (not hydrolyzed).
Its amino acid composition is very similar to that of human
Application collagen Type I.
 moisturizing

in vivo ex vivo in vitro

Maricol S    

Due to its film-forming and skin-protective properties, Dosage: 3.0–10.0%

Maricol S is especially suitable for the care of dry and mature pH range: 4.5–6.5
skin as well as skin stressed by negative environmental
influences. INCI Name: Soluble Collagen

Maricol S is a native soluble collagen of marine origin, ob- Maricol S

tained from fish skin. is preserved with sodium benzoate.

Application
 moisturizing

in vivo ex vivo in vitro

Elastin CLR   

Elastin CLR can be used in skincare concepts for any type Dosage: 5.0–10.0%
of skin, but is particularly suitable for anti-aging skincare pH range: 3.0–10.0
applications. It comprises a unique aqueous solution of
partially and mildly hydrolyzed elastin, ensuring the conser- INCI Name:
vation of its natural protein structures (α-elastin, approx. Hydrolyzed Elastin
70 kD).
Elastin CLR
The structure of Elastin CLR is similar to tropoelastin, the is preserved with sodium benzoate.
monomer which is synthesized by skin fibroblasts as the
basic building block of elastin fibers.
Application
 moisturizing

11
SENSITIVE AND OILY SKIN

AnnonaSense CLR™
Adaptogenic approach
for skin health and well-being

in vivo ex vivo in vitro

AnnonaSense CLR™   skin  

AnnonaSense CLR™ provides the skin with means to estab- Dosage: 3.0%

lish a sustainable homeostatic balance, improving skin pH range: > 5.2
health and well-being. The potent adaptogenic action of
AnnonaSense CLR™ supports the skin’s endocannabinoid INCI Name:
system by activating the CB2 receptor. Through this action, Annona Cherimola Fruit Extract
it reduces inflammatory processes induced by TRPV1.
Histamine-, as well as TNFα / Substance P-induced stress is AnnonaSense CLR™
down-regulated and the expression of a vital detrimental is preserved with
receptor in skin, IL-31RA, is decreased. AnnonaSense CLR™ sodium dehydroacetate and
makes the skin less sensitive and more balanced, even itch is phenylpropanol.
Application perceivably reduced. Skin appearance is improved and the
 soothing, calming, perception of well-being and quality of life is enhanced.
anti-stress
AnnonaSense CLR™ is obtained from Annona Cherimola,
common name Cherimoya, an edible fruit originating from
South America.

in vivo ex vivo in vitro

SyriCalm ™ CLR (PC)   skin  

SyriCalm™ is a natural product derived from Poria cocos and Dosage: 3.0%
Phragmites. It effectively reduces inflammation and strongly pH range: 3.0–8.0
supports skin in dealing with external stresses.
INCI Name:
Additionally, SyriCalm™ is designed to give effective support Water, Phragmites Communis Extract,
where the skin is challenged by environmental stress, e.g. Poria Cocos Extract
shaving, depilation or daily hygiene. It helps the skin recover
its natural balance. Also available as SyriCalm™ CLR
INCI Name:
Water, Phragmites Karka Extract,
Application Poria Cocos Extract
 soothing, calming,
anti-stress Both versions of SyriCalm™
 barrier maintenance are preserved with sodium benzoate.
and repair

12
 in vivo ex vivo in vitro
PhytoDefense CLR ™   skin  

PhytoDefense CLR™ is carefully designed for the care of Dosage: 3.0%

hyper-reactive and irritable skin. It essentially reduces the pH range: 4.0–7.0
sensitivity of skin by its goal-oriented approach to the most
important features of sensitive skin: burning/stinging/itching INCI Name:
sensations and skin redness. Skin irritations as well as skin Glycine Soja (Soybean) Oil,
redness are noticeably reduced. Dicaprylyl Ether, Magnolia
Grandiflora Bark Extract,
PhytoDefense CLR™ is obtained from Magnolia grandiflora, Lauryl Alcohol
known in traditional medicine for its potent calming and
soothing properties. PhytoDefense CLR™
Application is stabilized with a natural rose­mary
 soothing, calming, extract concentrate.
anti-stress

in vivo ex vivo in vitro

Modukine ™   skin  

Modukine™ is a milk-derived active ingredient which is Dosage: 0.5%

specifically designed for the effective regenerative care of pH range: 6.0–7.0
sensitive, dry and troubled skin. It is intended for any type of
skin which shows chronic and pronounced inflam­mation. INCI Name: Lactose, Milk Protein

Modukine™ acts as an extremely potent biological cell Modukine™ is unpreserved.

response modifier. It strongly reduces inflammatory pro-
cesses in the skin at a cellular level and helps to restore skin
barrier and normal skin functionality.

Application
 soothing, calming,
anti-stress
 moisturizing
 barrier maintenance
and repair

in vivo ex vivo in vitro

Lactokine ™ Fluid PF   skin  

Lactokine™ Fluid PF is a multifunctional agent, suitable for a Dosage: 2.0–5.0%

wide variety of skincare concepts. It effectively soothes and pH range: 5.8–7.0
calms skin, accelerating the reduction of skin redness and ir-
ritation after external stresses. Additionally, Lactokine™ INCI Name: Milk Protein
Fluid PF vitalizes and energizes skin cells and induces the syn-
thesis of collagen, yielding skin-smoothing and firming prop- Lactokine™ Fluid PF
erties, thus making it a potent anti-aging product. In other is preserved with phenoxyethanol
in vivo studies Lactokine™ Fluid PF was shown to be very and sodium dehydroacetate.
effective in skin lightening, reducing the production of mel-
anin. Also available as
Application Lactokine™ Fluid PF-H
 anti-wrinkle, firming, Lactokine™ Fluid PF contains a network of activated and sta- Halal-certified (1)
smoothing bilized signal molecules derived from milk.
 soothing, calming,
anti-stress
 skin lightening
 skin protection

13
 in vivo ex vivo in vitro
ProBioBalance CLR ™ NP   skin  
SENSITIVE AND OILY SKIN

ProBioBalance CLR™ NP activates cellular processes involved Dosage: 2.0–5.0%

in cellular nutrition and helps activate detoxification pro- pH range: 5.8–7.0
cesses. The metabolic activity of skin cells is increased, and
the skin’s immune system strengthened and protected INCI Name:
against environmental stress. The application of ProBioBalance Water, Lactose, Milk Protein, Bifida
CLR™ NP leads to reduction of skin inflammation and also Ferment Lysate
actively prepares skin for external stresses.
ProBioBalance CLR™ NP
ProBioBalance CLR™ NP consists of probiotic bifido cultures is stabilized with phenethyl alcohol.
which are suspended and disintegrated in a biologically
Application active milk-based matrix.
 soothing, calming,
anti-stress
 skin protection

in vivo ex vivo in vitro

Cutipure CLR ™   skin  

Cutipure CLR™ has strong and versatile anti-inflammatory Dosage: 3.0%

properties, an important feature for skincare products pH range: 3.0–8.0
intended to effectively support oily and acneic skin in order
to achieve quick results. It additionally shows strong anti­ INCI Name:
microbial properties with a broad antibacterial action. It Water, Taraktogenos Kurzii Seed
reduces pimples, pustules and comedones, and rebalances Oil, Nigella Sativa Seed Oil,
sebum production. Leptospermum Scoparium Branch/
Leaf Oil, Potassium Lauroyl Wheat
Cutipure CLR™ is a synergistic and polyvalent blend, based Amino Acids, Palm Glycer­ides,
on actives from chaulmoogra oil, black cumin oil, manuka oil Capryloyl Glycine, Magnolia
Application and magnolia bark. Grandiflora Bark Extract
 anti-acne
Cutipure CLR™
is preserved with phenoxyethanol.

in vivo ex vivo in vitro

Calendula Oil CLR   

Calendula Oil CLR is particularly suitable for skin and haircare Dosage: 3.0–10.0 %
concepts where soothing and calming properties are valued,
such as baby care, care for sensitive skin, elderly skin and INCI Name:
irritated scalp. Calendula has been extensively used in both Glycine Soja (Soybean) Oil,
traditional and modern medicine for its well-described anti- Calendula Officinalis Flower Extract,
inflammatory properties. Tocopherol

Calendula Oil CLR is obtained by an extremely mild extrac- Calendula Oil CLR
tion of the blossoms of Calendula officinalis in stabilized is stabilized with a natural
soybean oil. tocopherol concentrate.
Application
 soothing, calming, Also available as Organic Calendula Oil CLR, which is based
anti-stress on organic calendula blossoms and organic soybean oil
compliant with Regulation (EC) No 834/2007 on organic
production of agricultural products.

14
 in vivo ex vivo in vitro
Arnica Oil CLR   

Arnica Oil CLR is suitable for a wide variety of skin and hair- Dosage: 3.0–10.0%
care concepts, such as anti–hair loss, relief for troubled skin,
and after-sun care. Arnica is renowned for its ability to stim- INCI Name: Glycine Soja (Soybean)
ulate and heal the skin, which is illustrated by its extensive Oil, Arnica Montana Flower Extract,
use in the treatment of bruises and sprains. It is also known Tocopherol
for its calming and soothing properties.
Arnica Oil CLR
Arnica Oil CLR is obtained by an extremely mild extraction is stabilized with a natural
of the blossoms of Arnica montana in stabilized soybean oil. tocopherol concentrate.

Application
 soothing, calming,
anti-stress
 anti–hair loss

in vivo ex vivo in vitro

St. John’s Wort Oil CLR   

St. John’s Wort Oil CLR is particularly suitable for the care of Dosage: 2.0–10.0%
dry, sensitive and problem skin, chapped lips, and in the sup-
port of irritated skin. St. John’s Wort has been traditionally INCI Name:
used in medicinal applications to treat insect bites, Olea Europaea (Olive) Fruit Oil,
sunburn, bruises and edema. Hypericum Perforatum Flower/Leaf/
Stem Extract, Toco­pherol
St. John’s Wort Oil CLR contains the lipophilic components
of the aerial parts of the St. John‘s Wort plant (Hypericum St. John’s Wort Oil CLR
perforatum), collected when in blossom and gently extracted is stabilized with a natural
in olive oil. tocopherol concentrate.
Application
 soothing, calming,
anti-stress

in vivo ex vivo in vitro

Hexaplant ™ / Sedaplant ™ Richter   

Hexaplant™ Richter and Sedaplant™ Richter are applicable Dosage: 2.0–5.0%

in a wide variety of skin and haircare concepts, such as baby pH range: 3.0–10.0
care, and care for sensitive skin and scalp.
INCI Name:
Hexaplant™ Richter and Sedaplant™ Richter contain potent Hexaplant™: Water, Alcohol,
mixtures of extracts from fennel, hops, chamomile, balm Foeniculum Vulgare (Fennel) Fruit
mint, mistletoe and yarrow. Sedaplant™ Richter additionally Extract, Humulus
contains urea and allantoin. All ingredients are well known Lupulus (Hops) Extract, Melissa
and well appreciated in both traditional medicine and Officinalis Leaf Extract, Viscum Album
modern science, especially for their skin-healing and soothing (Mistletoe) Leaf Extract, Chamomilla
Application properties. Recutita (Matricaria) Flower Extract,
 soothing, calming, Achillea Millefolium Extract
anti-stress
 hair conditioning and Sedaplant™: Water, Alcohol,
protection Foeniculum Vulgare (Fennel) Fruit
Extract, Humulus Lupulus (Hops)
Extract, Melissa Officinalis Leaf
Extract, Viscum Album (Mistletoe)
Leaf Extract, Chamomilla Recutita
(Matricaria) Flower Extract, Achillea
Millefolium Extract, Urea, Allantoin
Hexaplant™ Richter and
Sedaplant™ Richter
are unpreserved.

15
BARRIER MAINTENANCE AND REPAIR

Modukine ™
Goal-oriented care for troubled skin

in vivo ex vivo in vitro

ProRenew Complex CLR ™   skin  

Based on probiotic technology, ProRenew Complex CLR™ Dosage: 3.0%

acts on essential features in the aging process of the skin, pH range: 4.0–7.0
its ability to successfully adapt to a constantly changing
environment and to effectively renew itself. INCI Name:
Lactococcus Ferment Lysate
ProRenew Complex CLR™ positively influences the speed
and quality of epidermal growth. It has shown to effectively ProRenew Complex CLR™
promote desquamation, the shedding of dead cells. is preserved with sodium benzoate.
ProRenew Complex CLR™ is beneficial for both the health of
skin and the skin microbiota. It balances and protects the Also available as
Application skin microbiota and supports it in dealing with day-to-day ProRenew Complex CLR™ NP,
 skin regeneration stress. stabilized with phenylpropanol and
 barrier maintenance levulinic acid/sodium levulinate.
and repair
 skin protection

16
 in vivo ex vivo in vitro
SyriCalm ™ CLR (PC)   skin  

SyriCalm™ is a natural product derived from Poria cocos and Dosage: 3.0%
Phragmites. It effectively reduces inflammation and strongly pH range: 3.0–8.0
supports skin in dealing with external stresses.
INCI Name:
Additionally, SyriCalm™ is designed to give effective support Water, Phragmites Communis
where the skin is challenged by environmental stress, e.g. Extract, Poria Cocos Extract
shaving, depilation or daily hygiene. It helps the skin recover
its natural balance. Also available as SyriCalm™ CLR
INCI Name: Water, Phragmites
Karka Extract, Poria Cocos Extract
Application
 soothing, calming, Both versions of SyriCalm™ are
anti-stress preserved with sodium benzoate.
 barrier maintenance
and repair

in vivo ex vivo in vitro

Vitamin F forte   skin   hair 

Vitamin F forte nurtures, protects and acts as a skin condi- Dosage: 0.5–3.0%
tioner. It is particularly suitable for the treatment of dry, pH range: 3.0–10.0
stressed and sensitive skin, potently supporting the skin in
rebuilding and maintaining its natural healthy structure and INCI Name:
functionality. Vitamin F forte also has some great benefits for Linoleic Acid, Linolenic Acid
hair (see the haircare section of this brochure).
Vitamin F forte
Vitamin F forte contains natural polyunsaturated essential is stabilized with a natural
free fatty acids originating from safflower oil, with a particu- tocopherol concentrate.
larly high content of linoleic acid.
Application
 moisturizing Also available as Vitamin F water-soluble CLR in water-
 barrier maintenance soluble form. In addition, essential fatty acids in ester form
and repair are available as Vitamin F Ethyl Ester CLR and Vitamin F
 hair conditioning and Glyceryl Ester CLR.
protection

in vivo ex vivo in vitro

Modukine ™   skin  

Modukine™ is a milk-derived active ingredient which is Dosage: 0.5%

specifically designed for the effective regenerative care pH range: 6.0–7.0
of sensitive, dry and troubled skin. It is intended for any type
of skin which shows chronic and pronounced inflammation. INCI Name: Lactose, Milk Protein

Modukine™ acts as an extremely potent biological cell Modukine™ is unpreserved.

response modifier. It strongly reduces inflammatory pro-
cesses in the skin at a cellular level and helps to restore skin
barrier and normal skin functionality.

Application
 soothing, calming,
anti-stress
 moisturizing
 barrier maintenance
and repair

17
 MultiMoist CLR™
Mapping the moisturization puzzle
HAIR CARE

in vivo ex vivo in vitro

MultiMoist CLR™   skin   hair 

MultiMoist CLR™ binds water in the cortex of hair, im­ Dosage: 1.0%
proving a variety of important hair qualities. It is a hair pH range: 3.0–8.0
conditioner, improving its combability and handling.
MultiMoist CLR™ also protects against color fading caused INCI Name:
by repeated washing with shampoo. It dramatically reduces Fructooligosaccharides, Beta
hair breakage from combing and MultiMoist CLR™ has a Vulgaris (Beet) Root Extract, Water
strong impact on static flyaway too. Hair frizziness is signifi-
cantly reduced as well. MultiMoist CLR™
is unpreserved.
MultiMoist CLR™ consists of a powerful synergistic blend of
Application fructooligosaccharides and beta vulgaris (beet) root extract.
 moisturizing
 hair conditioning and
protection

in vivo ex vivo in vitro

Follicusan ™  DP   hair  

Follicusan™ DP stimulates the functionality of the dermal Dosage: 3.0–5.0%

papilla cells at the base of the hair follicles, thus counter- pH range: >5.8
acting premature hair loss. It increases the number of anagen
hair follicles (growth stage) and decreases that of telogen INCI Name:
hair follicles (resting stage). Hair density as well as cumulative Water, Alcohol Denat., Panthenyl
hair thickness is increased. Ethyl Ether, Milk Protein, Lactose,
Inositol, Acetyl Cysteine, Acetyl
Follicusan™ DP contains biologically active signaling Methionine, Sodium Citrate,
proteins, ethyl panthenol (provitamin B5), inositol as well as Citric Acid
acetyl cysteine and acetyl methionine in a water-ethanol
Application medium. Follicusan™ DP
 anti–hair loss is preserved with phenoxyethanol
and sodium dehydroacetate.

18
 in vivo ex vivo in vitro
DayMoist CLR ™   skin   hair 

DayMoist CLR™ is a hair conditioner, improving hair comba- Dosage: 1.0%

bility and manageability. Additionally, it was shown to pH range: 3.0–10.0
positively influence the mechanical properties of hair and to
protect against fading of hair color in dyed hair. DayMoist INCI Name:
CLR™ also effectively protects hair against heat that is Water, Hydrolyzed Corn Starch, Beta
applied during hair straightening. Apart from these features Vulgaris (Beet) Root Extract
for hair care, DayMoist CLR™ is also proven to be a potent
skin moisturizer (see the moisturizer section in this brochure). DayMoist CLR™ is stabilized with
plant-derived anisic acid.
DayMoist CLR™ is a complex of natural plant-derived active
Application ingredients.
 moisturizing
 hair conditioning and
protection

in vivo ex vivo in vitro

Vitamin F forte   skin   hair 

Vitamin F forte is a strong hair conditioner, improving hair Dosage: 1.0%

combability, and has shown to protect against hair breakage. pH range: 3.0–10.0
In addition it has many positive features for skin (see the
section on barrier maintenance and repair of this brochure). INCI Name:
Linoleic Acid, Linolenic Acid
Vitamin F forte contains natural polyunsaturated essential
free fatty acids originating from safflower oil, with a particu- Vitamin F forte
larly high content of linoleic acid. is stabilized with a natural tocopherol
concentrate.
Also available as Vitamin F water-soluble CLR in water-
Application soluble form. In addition, essential fatty acids in ester form
 moisturizing are available as Vitamin F Ethyl Ester CLR and Vitamin F
 barrier maintenance Glyceryl Ester CLR.
and repair
 hair conditioning and
protection

Other active ingredients for hair care: Hygroplex™ HHG (p. 10)

LEGAL DISCLAIMER The information contained in this brochure, in particular data and test results, suggestions and formulas, is provided to the
best of our knowledge at the time of going to press. We do not, however, guarantee that it is up-to-date, correct, or
complete, nor do we guarantee the quality of the information provided in this brochure. Liability claims against us relating
to damages of a material or immaterial nature caused by using or not using the information featured in this brochure are
categorically excluded unless there is evidence of willful intent or gross negligence on our part.

The use of trade names, trademark rights, trademarks or other industrial property rights of other companies in this brochure
shall not authorize third parties to use them freely, as they may be the protected or registered rights of third parties even
if they are not expressly identified as such. The existence of any third-party industrial property rights must be investigated
independently and observed.

We retain the sole copyright to the entire content of this brochure and the industrial property rights to all designations of
our products stated in this brochure as well as industrial property rights to the products themselves. The duplication or use
of our product designations, images, graphics and texts is not permitted without our explicit written consent.
Berlin, 10.2019

19
 08 – 10.2019
2019 © CLR-Berlin 330-08-1910

CLR
Chemisches Laboratorium Dr. Kurt Richter GmbH
Sperenberger Straße 3 · 12277 Berlin · Germany
Tel +49 30 851026-0 · Fax +49 30 851026-85
info@clr-berlin.com · www.clr-berlin.com