+ Asymptomatic in men Glardiasis J, 1S Saused by G.Jamblia, the most commonly diagnosed intestinal parasite inthe United States {Transmission is through contaminted water or food, and trophozoites * Gheracterized by darhea, rotten egg-smeling stool, and pale and mucus-filed stool. Some patients experience epigastric pain, weight oss, and mainutitor Commonly used oral antiprotezoal drugs can be generally classified into two main grou miscellaneous antiprotozoals. In addition to their use as anti \doxycycine are also used for treating bacterial infections 19S:_antimalarial drugs and iprotozoa's, some of them such as metronidazole and I To reece ae cents used to attack Plasmodium at various stages ofits fe cycle. Trough this, i Decornge Possible to prevent acute malarial eacton in ineviduals who have Been infected by he page, + These agents can be: © schizonticidal (acting against the red-blood-cell phase >the life cycle), © gametocytocidal (acting against the gametocytes), Storontocidel.(acting against the parasites that are developing in the mosquito), or Schizonts as prophylactic or antirelapse agent work against tesue Quinine (Qualaquine) was the first d resistant plasmodial infections Chloroquine (Aralen): Prevention and treatment of plasmocial malaria; treatment of extraintestinal amebiasis talofantrine (Halfan): Treatment of plasmodial malaria in combination with otrer drugs Hydroxychloroquine.(Ptaquenl): Treatment of plasmodial malaria, in combination with ‘othet"drugs (particularly rimaquine) Mefloguine (Lariart): Prevention and treatinent Of plasmodial malaria in combination with other drugs Primaquine (generic) Prevention of lapses of Plasmodium vivax and Plasmodium malaria infections; Radical cure of P. vivax malaria 8 found to be etfective in the treatment of nialaria. Treatment of chloroquine- * Pyriméthamine (Oarapri) : Prevention of plasmodial malaa in combination with other agents to suppress ‘Therapeutic Action of antimalarials is: * Enlering human red blood cells and changing the metabolic pathways Necessary for the reproduction. Chloroquine, the ‘mainstay of treatment, in addition to this main mechanism, is gitecty tone ts Parasites and decreases the ability of the Parasite to synthesize DNA ‘+ Interrupt plasmodial reproduction of protein synthesis * Agents that de not appear to affect the sporozoites are used for prophylax Contraincleations: Known allergy, Liver disease, Alcoholism, Lactation * Cautions: Retinal disease or damage, Psoriasis Adverse Effect: # Headache, Dizziness, Fever, Chis, Maleiss, Nausea, Vomiting, Hepatic dysfunction Drug-to-Drug Interactions. {Quinine derivatives and quinine create risk for cardiac toxicity * Aatlolate drugs with pyrimethamine can increase risk of bone marrow suppression Other Antiprotozoal Drugs * ators: Inhibiting ONA synthesis in susceptible protozoa, intrtrinowits cal's ability to reproduce, subsequently leading to cell death, Contraindications: Known allergy, pregnancy, CNS dist east, and hepatic disease * Adverse reactions: Headache, dizziness, ataxia, naust a, vomiting, and diarrhea CHECK FOR UNDERSTANDING (30 minutes) You mill answer and rationalize this by yourselt. This will be recorded 8 your quiz. One (1) point will be given to correct li answer and. ancther one (1) point for the correct rationalizatis Superinspositions or erasures in you answerfratio is not allowed: You're civen 25 minstes for this activity Multiple Choice This cocument end the information thereon isthe property of PHINMA Education (Department of Nursing) 6of9+. Apatientrecaving torical anttungal carps of blstarsin her panaum, Which sare a possi explanations fr is a. Fungal infection is not healing. . b. Patient is allergic to the drug. c. Both Aand B d. None of the above ANSWER: RATIO:_“Fhe geeveu expe viell he, Harter cond Alioonafeet b un Elen ect tape Eacealag neg pice Nb 2. With ofthe folowing wi eet he nurse fr paste avr fect pales receiving long-term itraconazole therap ‘a. Central obesity b. Cataract . Thickening of the skin 4 a ANSWER: RATIOL_Tataronayle lio ay pelt tp tangy? he ache oF dea torhin ee vk i rHiel ath ah saul ome 3. An eight (8) month old infent i ecelving antl, Which should be inctuded in the nurse's health teaching to the mother’ a, Cover the area of lesions with diaper to prevent additional infection. . Make sure area is free from occlusive dressings. ‘c. Apply more topical cream on draining areas because itis where fungi are most d. Advise that redness and rashes are negligible side eifects of antifungal therapy and should not be a cause of worry. ANSWER: may coat Lec atin andro tt 4. Which of these antifungals can be used in pregnant women? a. Fluconazole b. Nystatin . Ketoconazole <é. Amphotericin B ANSWER: iD : RATIO“ (pill ampite ef (bi tox Avrrhotictin soaint He Safest gotten! 5, Aric, a 16-year-old student, has acquired systemic fungal infection, he should be treated with: a. Amphotericin B . Miconazole (Monistat IV) c. Ketoconazole 4. Griseofulvin (Fulvicin) Be con dal opel stil ct nba Which ofthe following must auways be present before beginning antifungal therapy? Coagulaiion profile Confirmad diagnosis Biopsy «if infected site |, Urinalys is ANSWER: By __ aogee This document and the information thereon isthe property of rot PHINMA Education (Department of Nursing)RATIO: Dye Ww the fart yrad fetta) algo bir fy Unhoradi ca fy kaw itn 4 Yt dundee en et Eee et paihie 7. A 22-year-old woma7 presents to her gynecologist with a 4 days history of perineal prurtus and a non-malodorous, thick, cheesy vaginal discharge. The only medication the woman is taking is an oral contraceptive. A wet preparation of vaginal secretion shows budding yeast cells and pseudohyphae, Whict of the following drugs, given locally, would be appropriate for this patient? a, Mebendazole b. Metronidazole ©. Miconazole 4. Saquinavir ANSWER: RATIO: Hitmedanile athe eat apenphale for Ue phe &. The nurse sees @ pavent in the clinic who has been taking chloroquine for the treatment of malaria, While the nurse {easures vital sians, the pauent repeatedly rubs her eyes. When the nurse questions why, the patient says, "lquess i's {ime for a trip to the eye doctor. My glasses don't seem to work very well and I'm having trouble with my vision.” What does the nurse suspect is happening with this patient? a. Adverse effect of medication b. Muscles controlling the eye are impacted by malaria ©. Chemica! actions f the medication are reducing aqueous humor isdamaging optic tissue : ct. abe, _sptotey Har avin dhlocgine i Vina problems. Ht va deact a po ey Fae opal a tag 8. The nurse is caring fora patient taking antimalarials for prophylaxis while serving in the Peace Corps in Afica, The Fang ;nas taken the medication for 2 months end is continuing to lose significant weight due tothe Gl effects ofthe drug. [eaztrecommendations can the nurse make to reduce SI adverse effects and promote healthy nutiven tor hve Patient? (Select all that apply.) ‘a. Avcid alcohol, . Add extra fatto diet for calories. ©. Take the drug immediately after meals, d. Eat 5 to 6 small meals a day. ANSWER: vend Page thot ere ha plat cemoeedahinn dy SSA ee 2017, ht Co, the. fob 10. An instructor is describing the action of primaquine, What would the instructor include? a. Tne drug blocks the us2 of folic acid ». WWchanges the metabolic pathways for reproduction . ¢. The drug increases the acidity of plasmodial food vacuoles, 4. Itcisrupts the mitochondria, kiling the gametocytes. “ANSWER: RATIO!_ “fins Jy aud Jong Jalec funn Za fact vp the paaute whuh fuppliey jp i ec Thy iy he aa decade RATIONALIZATION ACTIVITY (THIS WILL BE DONE DURING THE FACE TO FACE INTERACTION) Wiauisttuctor wil now rationalize the answers to the students, You can now ask quectone are debate among yourselves. Write the correct answer and correc/additional ratio in the space provided 1. ANSWE? This document and the information thereon is the property of PHINMA Education (Depariment of Nursing) 8 of9RATIO: 2. ANSWER: = RATIO: 3. ANSWER: RATIO: 4. ANSWER: RATIO: 5. ANSWER: RATIO: 6. ANSWER: RATIO; 7. ANSWER: RATIO: 8. ANSWER: % RATIO: 9. ANSWER: a - RATIO: LESSON WRAP-UP (5 minutes) ‘You will now mark (encircle) the session you have finshed today in the vacker below. Ths is simply a visual tohelp you track how much work you have accomplished and how much work there is lef to do. ‘You are done with the session! Let's track your progress. ee Petod 1 Period 2 Period 3 | GOTO s Is rele pol ae pais] ee ep oo 2 | 22 [zs] 24] 25] 26 [a7 [eT 210) MINUTE PAPER ‘Compose (wo to three sentences to explain what-cha/he has leaned using the key ideas listed in lesson review. “learned We deffeewnt Sul infertions aloo % Ye ny i waht a“ Nd tho wwe, Yh yt " i Peet ake Fornont sssion review anvil and avhelmiite, ” "CV%" the effects ay medaintion foven yy Berit pee, ‘a RR I aN SPI REE 3 This document and the information thereon isthe prope.ty of PHINMA Education (Department of Nursing) 9of9