Pharmacology § ox STUDENT ACTIVITY SHEET BS NURSING / SECOND YEAR Session 5 Materials: LESSON TITLE: ANTIVIRAL & ANTHELMENTIC DRUGS Notebook, Pharmacology book, drug handbook, pers & paper LEARNING OUTCOMES: At the end of the lesson, the nursing student can’ References: 1. Name several antiviral drugs and their uses; 2. Identify the various helminthes and the human body Kee, Joyce LeFever, Hayes, Evalyn R. & sites used for their infestation; McCuistion E. Pharmacoloy A Nursing 3. Describe action of anthelmintic: Process Approach 6" edition... Singapore: 4. Identify several nursing interventions for antiviral and Elsevier Saunders Company. anthelmintic drug ‘erapy; and. Develop a drug study guide (therapeutic action, indication, contraindication, most common adverse reaction And nursing responsibilty ) of antiprotozoal ad anthelmintic, LESSON REVIEW/ PREVIEW OR HOOK ACTIVITY (5 minutes) EVERYBODY WRITES How did the Pandemic (COVID 19) of 2020 affected you and your family? ——wal ‘ a tgp legit, ete ft ead et alee er he bode “oF ek family, wy Urn Ya Lye raping Ve td orge MAIN LESSON (50 minutes) ANTIVIRAL, Antivirals are agents used to treat the diseases caused by viruses such as warts and common colds. + Viruses are composed of a single DNA or RNA inside a protein coat. Viruses must enter a cell in order for them to carry or with their metabolic processes. ‘+ Upon successful entry, viruses inject their DNA or RNA to the cell and thz- cei is altered in such a manner that tis now “programmed to conirol the metabolic processes that the virus needs to survive. ‘+ Because viruses are contained in the cells, researchers find it dificult to develop vaccines. However, viruses respond to some antiviral therapy including influenza A viruses, herpes viruses, CMV, HIV, hepatitis B and C viruses, and some viruses that cause warts and eve infections, Viruses That Respond to Antiviral Therapy + Influenza A and some respiratory viruses Herpes viruses Cytomegalovirus (CMV) Human immunodeficiency virus (HIV) that causes acquired immune deficiency syndrome (AIDS) ‘Some viruses that cause warts and certain eye infections ET TS EE A This document and the information thereon isthe property of PHINMA Educetion (Department of Nursing) POY LotAo‘+ Albendazole with dexamethasone Increases the overall effect of the drug Uso of Antholrnintic Agents Across the Lifespan ie rg : Anthelmintic Agents HiLORE Culture of he suspected wor 'sitsortantbelore beginnang ary drug therapy. The mar te rugs—atvendazole, erect ane prariqsntet— ‘son be avelded in eiren, The most commenty used anthelmintic, medendazole, comes na chewable tablet thats convenient for use in citren, Hotitona status ang iydraion are major concerns with chiren taking these drags who develop serous gastrointestinal etfecs, ADULTS ‘Aduts may be somewhat repulsed by the idea tat they have a worm Infestation, nd they may be relu-tant to discuss the needed Mestyle adjustments and teatment plans. CHECK FOR UNDERSTANDING (30 minutes) Pregnant ané nursing women should not use these drugs uness {he benefit cleary outweighs the potential sk tothe fetus or neonate IVa severe helminth intestation threatens the mother, some of the ‘rugs cam be used as long as the moter is informed ofthe potential fis toer patents may be more susceptbe to he Cetra nenous system and gastrointestinal fects «sor of those drugs. Dosage achusiment ‘3 needed for Diese agers. Montr tyration and nutonal status careful. You will answer and rationalize this by yourself. This will be recorded as your quiz. One (1) point will be given to correct answer and another one (1) point for the correct rationalization. Superimpositions 0 erasures in you answerratio is not allowed. You are given 25 minutes for this activity je Choice 1. Patient X has genital herpes and is using antiviral creams for her condition. Which cf the following is a potential side eltect of the medication? a. VuNitis 5 set cleHanehn of ths Wwlve And ib a goterha fils offr-t 3 2. J 15 ylo patient came in fora severe case of respiratory fu and would need drug therapy. Which ofthe folowing drugs should the nurse anticipate to be prescribed? a. Acyclovir (Zovirax) b. Amantadine (Syrmetre!) c. Abacavir (Ziage1) 4d. Ganciclovir (Cytovene) ANSWER: RATIO: ine . uyed Zidovudine Acyclovir Osettamivir Selzenty ANSWER: __C/ peges ert ab een AL Which of the following antiviral agents is effective as treatment for H1N1? ER MELE TR, Pa This document and the intonation thereon is the property of PHINMA Education (Department of Nursing) Tof 10AMO. _Cdenpungd 40 day poh 4 Zanamivis, Ole\tamivir I Sfer to ye a raat heat dec —Indbernan JA oo a wd 4. student nurse administering acyclovir was asked by the clinical instructor on how the drug works. The student nurse would ‘be correct by stating that this drug works In which way? . ‘2, Unknown; but its believed to be shedding the protein cuat ofthe virus, 'v, i competes with viral receptors found in the host cells ittakes away the necessary substances neaded by viruses to form DNA chains 4, Trapping the viruses and disintegrating them diractly out my Ve vedas tvhaltanes newdod log Ue, Viruses t paw Slt tes ee fel ey a i Titty ap \Which of the following prescribed antiviral unould the nurse question for a patient with severe hypokalemia? . Foscamet . Cidofovir Valganciclovir |. Nevirapine ANSWER: . RATIO:N_Fypo Flamin ta lew potmerm Mined, on Hy eller bend poccarnet tan” Dakwial ding the law ued vl leg de ne ¢ “eoreppliontn ench “ate Which enzyme is essential fr the maturation of infectious viruses? Reverse transcriptase Protease Nucleosidase |. CORS-ase, ANSWER: RATIO: Ravens As épenbal agent nevfed fr padre ben 6e Indesit zy) 7. A senior nurse would be correct to advise her colleague to monitor which parameter in patients receiving cyclosporine and zidovudine at the same time? ‘a. Skin lesion, temperature, and color . b. Flusike symptoms . Level of consciousness d. CBC with differential count ANSWER: RATIO “That beats — Vo diy orn caste dete slap and (eter ay « £8. The only protease inhibitor that is not teratogenic. 1. Darunavir b. Indinavir ©. Fosamprenavir d. Saquinavir ANSWER: _ RATIO _Taguinavir ty Uo pny P-Haue inthe Heat oy rota Hemminga: i 7 i. 8. Which of the following physical assessment findings wil alert the nurse for anthelmintic drug toxiiy in elderly patients? a, Muscle strength +2 ». Blunt liver edge upon palpation . 10 bowel sounds in one minute on right lower quadrant (RLQ) upon auscultation 4. Non-palpable spleen ANSWER: This docu nent and the information thereon is the property of PHINMA =ducation (Department of Nursing) 8 of 10RATIO: Si low ae Sige aan bi vada Lf hegatemeaaly oe waster tng 40,.Which drug is indicated for threadworm infections? a. albendazole b. ivermectin =f c. pyrantel d. mebendazgle ANSWER: PATO. Wermadimn 9 yf te reat Dreads tadetbrb rnc @ RATIONALIZATION ACTIVITY (THIS WILL BE DONE DURING THE FACE TO FACE INTERACTION) Tha instructor will now rationalize the answers to the students. You can now ask questions and debate among yourselves. Wiite the correct answer and correctadditional ratio in the space provided 1. ANSWER: RATIO: 2. ANSWER: RATIO: 3, ANSWER RATIO:_ 4, ANSWER: RATIO: 5. ANSWER: RATIO: : 6. ANSWER: RATIO: 7. ANSWER: RATIO: 8. ANSWER: RATIO: 9. ANSWER: RATIO: 10, ANSWER: RATIO: This document anc! tho information thereon is the property of PHINMA Education (Department of Nursing) 9 of 10LESSON WRAP-UP (5 minutes) ‘You will now mark (encircle) the session you have finished today in the tracker below. This s simply a visual to help you track how niuich work you have accomplished and how much work there is left to do. You are dene with the session! Let's track your progress. ie Patiod 1 Fenod? Poviod 3 PLOT COLE) [7 Tee Lol eae as ea] a5 [ 16 [7 [rw vo 20 EEE AEE THREE W's Students discuss or write: | * What did you learn today? ~ | (earnad the differ t ombiyirn diva * So What? (relevancy, importance, usefulness) Tt y+) lenpertnt fe fmm whet nyt wedramtio pp ‘+ Now What? (how does this fit into what you are learning, does it affect your thinking) , gue YO, now Ly enw tnt breathy) Putivies 9 met on coy uk berquit “ al ti) De cells ; i For the next lesson review antineoplastic. NI a moms This document and the information thereon ws thé property of PHINMA E'ucation (Department of Nursing) 10 of 10