Professional Documents
Culture Documents
doi: 10.1016/j.bjae.2022.03.006
Advance Access Publication Date: 15 June 2022
298
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Awake tracheal intubation
airway and awake tracheostomy, but this article will focus to achieve successful tracheal intubation in the awake pa-
upon conventional intubation with a tracheal tube.2 tient where ATI:FB alone may have failed. It requires a
ATI is indicated in any patient with predictors of difficult minimum of two experienced operators, the first using vid-
tracheal intubation or face mask ventilation; these may stem eolaryngoscopy to optimise the view of the larynx and
from pre-existing patient factors or as a consequence of the displace the epiglottis. The second operator uses the flexible
presenting pathology.5 In cases of recognised difficult laryn- bronchoscope as a steerable bougie to intubate the trachea
goscopy and tracheal intubation, where facemask ventilation and subsequently use the bronchoscope as an introducer for
is possible, asleep techniques may be considered more the tracheal tube.4,9e11
appropriate, and it is useful to develop these skills for the
management of the unpredicted difficult airway. Absolute
contraindications to ATI are limited only to the patient’s
Preparation for the procedure
refusal, despite appropriate explanation. Relative contraindi- ATI, especially in the context of difficult airway management,
cations include: allergy to local anaesthetic, airway bleeding is associated with considerable stress for the operator.
(where blood may obscure the image achieved through a Consequently, preparation, planning, teamwork and
flexible bronchoscope or videolaryngoscope), the uncoopera- communication are all essential for optimal performance.12
tive patient and certain airway tumours (with the potential to Recent guidelines support clinical experience that the oper-
cause a ‘cork-in-bottle’ airway obstruction).3 atong theatre environment is the optimal location for per-
forming ATI.2 Association of Anaesthetists guidelines for
patients receiving sedation should be followed.13 A second
ATI:FB anaesthetist should be present and responsible for injecting
Fibreoptic intubation was first performed in the 1960s and and monitoring the effects of sedation. The importance of
thereafter, bronchoscopes have become a mainstay of diffi- well-trained assistants cannot be overestimated and check-
cult airway management. The oral or nasal route for ATI:FB lists form an aide memoire in clinical emergencies. The DAS has
should be selected carefully, based upon factors related to produced a checklist that can be updated for local practice (Fig
the patient, surgical access and the equipment available. No 1). As a procedure that is performed infrequently by many
single route has been shown to be superior when both are anaesthetists, this checklist provides an easily accessible
possible.2 The length, tip design and material must be point of reference, and aims to both increase the use of ATI
considered when choosing the tracheal tube for performing where indicated, and improve its safety when performed.
ATI:FB. Railroading (passing the tracheal tube over the flex- Ergonomics contribute to successful performance of technical
ible bronchoscope) and impingement on the larynx are po- skills.14 No individual set up has been shown to be superior,
tential barriers to successful ATI:FB. Numerous tracheal but one possible layout as suggested by DAS is illustrated (Fig
tubes can be used for ATI:FB; reinforced flexometallic, intu- 2). The authors advise that operator, bronchoscope, patient
bating laryngeal mask airway (ILMA) and nasotracheal tubes and screen are aligned for optimal comfort.3 Positioning the
can all be used.3 The size and external diameter of flexible patient in the semirecumbent position offers anatomical and
bronchoscope selected for ATI:FB should also be part of physiological advantages to performing ATI.2
decision making. The authors choose to preload the flexible
bronchoscope with a size 6.0 cuffed ILMA tube. The soft tip
and malleability mean that it is suitable for both oral and
Oxygenation
nasal routes of intubation, and is less likely to impinge on the The indications and clinical scenarios where ATI is consid-
larynx during railroading. ered mandates the use of supplementary oxygen therapy.
The incidence of desaturation (SpO2 <90%) varies depending
on the delivery device. High-flow nasal oxygen (HFNO) is the
ATI:VL authors’ oxygen delivery method of choice with reports of
Videolaryngoscopy has increased in popularity over recent lower incidence of desaturation when compared with low-
years. The COVID-19 pandemic has seen its use further flow devices.15 Traditional nasal cannulae or an inverted
encouraged in and out of the operating theatre, and it has Hudson mask offer alternative options where HFNO is
been further recommended as the default airway manage- unavailable.
ment technique as we enter the endemic phase of the
disease.6 Its advantages include technical familiarity with a
similar success rate and safety profile to ATI:FB.7 ATI:VL
Topical anaesthesia
does not affect time to intubation, when compared with Adequate airway topical anaesthesia is vital to the success of
ATI:FB.8 In addition, no further considerations are needed ATI approaches and lidocaine is commonly used for this
in respect of tracheal tube selection over an anaesthetist’s purpose. It is available in a variety of pharmaceutical prepa-
normal practice. However, additional equipment such as a rations, including combination with vasoconstrictors (such as
bougie or stylet should be prepared.2 At present, no single adrenaline [epinephrine] and phenylephrine) which reduce
videolaryngoscope has been shown to be superior for the likelihood of epistaxis when nasal intubation is preferred.2
ATI:VL and therefore current recommendations suggest The maximum prescribed dose for topical anaesthesia is 9 mg
using the equipment with which the operator is most kg 1, although in practice doses this high should not be
familiar.2 required by those experienced in ATI. Cocaine has the
advantage of intrinsic vasoconstrictor activity but concerns
regarding its adverse cardiovascular effects mean its use is no
VAFI longer recommended.
A number of case reports have described a technique using Local anaesthetics can be nebulised, given by a ‘spray-as-
both flexible bronchoscopy and videolaryngoscopy, in order you-go’ technique, via a variety of devices, or via nerve
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Awake tracheal intubation
1. Location
2. Appropriate staff present
Anaesthetic assistant Second anaesthetist
monitoring, sedation, anaesthesia
Other
3. Team briefed
Procedure outline Role allocation
Route Device/blade
5. Oxygenation
6. Sedation (if required)
7. Topicalisation Maximum lidocaine dose
kg × 9 mg.kg–1 = mg
Nose Oropharynx Larynx Trachea Planned lidocaine dose
sprays of 10% mg
Vasoconstrictor (if required) Antisialogogue (if used) ml of 2% mg
ml of 4% mg
8. Setup position
Operator Patient Monitor Suction
Fig 1 The DAS checklist for awake tracheal intubation in adults. SAD, supraglottic airway device.
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Awake tracheal intubation
A B
,
TI XY IC
EN
C , O ET
O G
SU NE TH
H AES
N
ANAESTHETIC
MACHINE, OXYGEN,
AC N
M A
I
SUCTION
OPERATOR ASSISTANT
IT T
N N
VI NIT
R
M
O IE
D O
O
O
M AT
EO R
MONITOR
PATIENT
P
AI OL
TR
RW L
PATIENT PATIENT
AY Y
E
AI OL
PUMPS
OPERATOR TR
RW L
AY Y
M VID
O E
E
N
IT O
O
R
PUMPS ASSISTANT SECOND
ANAESTHETIST
SECOND
ANAESTHETIST
Fig 2 Suggested ergonomics for the performance of awake tracheal intubation. Alongside pictorial representation of the ergonomics and equipment required.
blocks to the superior laryngeal and glossopharyngeal performed with a suitable cannula, it can be used for rescue
nerves.16 There is insufficient evidence to recommend a oxygenation, and provide a conduit for passage of a guidewire
single technique, but nerve blocks are associated with facilitating Seldinger tracheostomy in cases of failed intuba-
increased plasma concentrations of local anaesthetic.2 tion or airway obstruction.
Variation in practice may exist between anaesthetists for Adequate airway topical anaesthesia is vital to the success
achieving airway anaesthesia. The authors’ preferred of ATI techniques. Atraumatic assessment of topical anaes-
method has proved effective over years of clinical use and is thesia with a soft suction catheter or Yankauer sucker should
outlined below (Table 1). be performed before ATI attempts.2 This has the added benefit
Cricothyroid puncture and transtracheal local anaesthetic of clearing any secretions or accumulated local anaesthetic
injection can provide airway anaesthesia. In addition, if before intubation.
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Awake tracheal intubation
Table 1 Authors’ technique for ATI. MAD, mucosal atomisation device; TCI target-controlled infusion; TT, tracheal tube.
Nose Cophenylcaine (0.5 ml) via MAD to Second anaesthetist to manage 0 min
each nostril sedation
Pharynx Lidocaine 10% spray (10 mg per Remifentanil TCI
spray) Start with low target concentration
1 Spray to tip of tongue (e.g. 0.5e1 ng ml 1)
6 Sprays to base of each tonsillar Increase to maximum 3 ng ml 1
pillar (0.5 ng ml 1 increments)
Larynx Lidocaine 2% via epidural catheter
inserted via suction port of scope.
2 ml above vocal cords Deep breath 1
2 ml below vocal cords Deep breath 2
Pass scope through cords Deep breath 3
Pass TT through cords Deep breath 4
(Alternative injection via MAD if
ATI:VL preferred)
5 min
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Awake tracheal intubation
100% OXYGEN
STOP SEDATION 100% oxygen can be given via facemask,
P HFNO or SAD (if adequately topicaIised)
O
S Immediate airway management is
T STOP essential when:
P No AND • Airway patency is compromised
O THINK • Ventilation is compromised
Prepare for emergency FONA
Yes
Consider
• Patient factors - anatomy, compliance
• Skill availability - anaesthetist
ATI: FONA or surgeon competence
appropriate? • Equipment availabiIity
Fig 3 DAS failed ATI algorithm. FONA, front-of-neck access; SAD, supraglottic airway device.
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Awake tracheal intubation
the differences between manikins and patients, without the laryngoscopic tracheal intubation in patients with antic-
anxiety of intubating awake patients with continued learning ipated difficult airway managementda randomized clin-
of the motor skills required. Learners progress to ATI:FB where ical trial. Anesthesiology 2012; 116: 1210e63
clinically indicated, but airway assessment predicts normal 9. Go mez-Rı́os MA, Nieto Serradilla L. Combined use of an
anatomy, for instance, in a patient with limited cervical spine Airtraq® optical laryngoscope, Airtraq video camera,
range of movement. Subsequent exposure to increasingly Airtraq wireless monitor, and a fibreoptic bronchoscope
abnormal airway anatomy increases expertise and problem- after failed tracheal intubation. Can J Anesth 2011; 58:
solving skills. Competence should be demonstrated at each 411e2
stage before progression to the next and expertise in man- 10. Chung MY, Park B, Seo J, Kim CJ. Successful airway
agement of the difficult airway should be the final goal.23 management with combined use of McGrath® MAC video
laryngoscope and fiberoptic bronchoscope in a severe
Declaration of interests obese patient with huge goiter e a case report. Korean J
Anaesth 2018; 71: 232e6
The authors declare that they have no conflicts of interest. 11. Liew GHC, Wong TGL, Lu A, Kothandan H. Combined use of
the Glidescope and flexible fibrescope as a rescue technique
MCQs in a difficult airway. Proc Singap Healthc 2015; 24: 117e20
12. Miller T, Miller T, McCann A, Stacey M, Groom P. Cogni-
The associated MCQs (to support CME/CPD activity) will be
tive psychology, the multidisciplinary operating theatre
accessible at www.bjaed.org/cme/home by subscribers to BJA
team, and managing a cannot intubate, cannot oxygenate
Education.
emergency. Br J Anaesth 2020; 125: e12ee15
13. Association of Anaesthetists of Great Britain and Ireland.
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exclusivamente. No se permiten otros usos sin autorización. Copyright ©2022. Elsevier Inc. Todos los derechos reservados.
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