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 Genetics

 Susceptibility Factors
Psoriasis  Injury to the skin
 Alcohol
Legend: Insert Definition here
 Metabolic Syndrome  Smoking
Disease process  Stress
 Type II Diabetes
Psoriasis  Hormonal changes
Complications  Obesity  Medications (lithium, antima-larial, anti-
inflammatory, ACE inhibitors)
 Depression
Diagnostic Tests  Streptococcal Infection
 Cardiovascular Disease Unknown Etiology  Immune Disorders
Medical Management

Medications
Pathophysiology

Disease
Migration of T cells, dendritic cells,
Types and Classification macrophages to epidermis

Predisposing factor
Release of inflammatory cells
Precipitating factor

Signs and Symptoms Stimulation of keratinocyte


Vascular engorgement
proliferation
Side Effects

Nursing Diagnosis Keratinocytes migrate to


stratum corneum in
Nursing Interventions 3-5 days

Keratinocytes do not lose


their nucleus

Immature Keratinocytes

Keratinocytes do not adhere well


to each other

Psoriasis

Plaque Psoriasis Guttate Psoriasis Inverse Psoriasis Postural Psoriasis Erythrodermic Psoriasis Nail Psoriasis

 Raised and inflammed red  Small, drop-shaped  Pus-filled lesions with red  Pitting nails
 Red, smooth patches of  A peeling rash that covers the
patches of the skin covered in papules, scaling spots borders  Nail discoloration
inflamed skin that worsen
a silvery scale
 On the trunk and  Widespread patches or on entire body that can itch or
with friction and sweating
small areas of the hands  Crumbling beneath free edges
 On elbows knees scalp lower proximities  On folded areas of the skin
burn intensely
back hands and feet and feet  Separation of the nail plate

 There is no cure, only Topical Agents Topical corticosteroids


Nonsteroidal topical
management of symptoms medications
 Lifestyle assessment
 Management of emotional  Skin irritation/redness or
 Physical Exam
factors
 Burning or stinging
small red bumps on the
- presence of the plaque-type sensation
 Patient education on the dis- ease skin (folliculitis)
lesions
and treatment
- signs of nail and scalp
involvement  Gentle removal of scales
 Family history  Encouraging patient to establish a
 Biopsy regular skin care routine Phototherapy UVB UVA

 Nausea and vomiting,


 Burning sensation
irritability, and
Impaired skin integrity Disturbed body image Deficient knowledge insomnia.

 Assess skin, noting color, moisture,  Assess the patient’s  Explaining the factors that
texture, temperature; note perception of changed provoke psoriasis
Systemic Agents Immunosuppressants Monoclonal antibody Fusion protein
erythema, edema, tenderness. appearance.  Explain treatment plan
 Identify aggravating factors and  Assess the patient’s behavior  Emphasize the importance of
encourage patient to avoid them. related to appearance. compliance  Fever or chills
 Advised the patient not to pick at  Allow patients to verbalize  Caution patient about taking  Fever or chills
 Pain in the side of the  Sore throat.
or scratch the affected areas feelings regarding their skin any nonprescription  Weakness
 Advice the patient to bathe or condition. medications. lower back  Dizziness
 Headache
shower using lukewarm water and  Assist the patient in  Advise the client receiving  Trouble urinating  Cough
systemic cytotoxic therapy to;  Nausea ·and zomiting
mild soap or nonsoap cleansers. articulating responses to  Pain while urinating  Nausea
 After bathing, allow the skin to air questions from others continue taking the  Diarrhea
medication even if nausea and  Frequent urination  Itching.
dry or gently pat the skin dry. regarding lesions and  Low BP
contagion. vomiting occur, increase fluid  Fatigue
Avoid rubbing or brisk drying.
intake, and to avoid alcoholic
 Apply topical lubricants  Assist patients in identifying
beverages.
immediately after bathing. ways to enhance their
 Instruct the client to avoid sun
 Apply topical steroid creams or appearance.
exposure during
ointments as indicated photochemotherapy.
 Apply topical  Give the client educational
immunomodulators as indicated materials that include a If not treated If treated
 Prepare the patient for description of the therapy
phototherapy as indicated and specific guidelines
 ↑ risk of major depressive The prognosis of this disease is
disorder
the same as for the general
 ↑ risk of cardiovascular
disease population, except in cases
 ↑ psoriatic Arthritis (up to where there are associated
30% of patients) cardiovascular risk factors or
 ↑ risk of chronic desease (e.g. other diseases independent of
Crohn’s, Uveitis)
psoriasis.

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