Cohort and Case-Control

Study
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Review
 What’s the Design?

Define treatment and control groups.

Administer exposure to treatment group, but not/or

controls.
Follow through time and compare rate of disease in
treatment group with rate of disease in control group.
Epidemiologist is involved during the entire time from
exposure and disease.

Randomized Trial
 What’s the Design?

Select a subject study sample.

Observe who is exposed and who is not exposed.

Follow through time and compare rate of disease in
exposed group to rate of disease in unexposed group.
Epidemiologist is involved during the entire time from
exposure and disease.

Cohort Study
 What’s the Design?

Select a group of people with disease and a similar group

of people without the disease.
Ask both groups about their exposures in the past.
Compare proportion of exposure in diseased group to
proportion of exposure in non-diseased group.
Epidemiologist is involved after disease has occurred
and relies on subjects’ memories to gather information
about exposure.
Case-Control Study
 What’s the Design?
Select a study sample.

Ask each person about both exposure and disease at that

point in time.

Disease rate in exposed group is compared to disease rate

in unexposed group.

Epidemiologist gathers data only at that one point in time.

Cross-Sectional Study
Study Design Exercise
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Case-Control Study
Study Design Exercise

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Cohort Study
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Randomized Trial
Study Design Exercise
Study Design Exercise

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Cross-Sectional Study
 Study Design Exercise

Select a healthy study sample.

Observe who is exposed and who is not exposed.

Follow through time and compare rate of disease in
exposed group to rate of disease in unexposed group.
Epidemiologist is involved during the entire time from
exposure and disease.
 Study Design Exercise

Select a group of people with disease and a similar group

of people without the disease.
Ask both groups about their exposures in the past.
Compare proportion of exposure in diseased group to
proportion of exposure in non-diseased group.
Epidemiologist is involved after disease has occurred
and relies on subjects’ memories to gather information
about exposure.
 Study Design Exercise

Define treatment and control groups.

Administer exposure to treatment group, but not controls.

Follow through time and compare rate of disease in

treatment group with rate of disease in control group.

Epidemiologist is involved during the entire time from

exposure and disease.
 Study Design Exercise

Select a study sample.

Ask each person about both exposure and disease at that

point in time.

Disease rate in exposed group is compared to disease rate

in unexposed group.

Epidemiologist gathers data only at that one point in time.