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7 ‘e %, Gain in bone mineral mass in prepubertal girls 3-5 years after — wer discontinuation of calcium supplementation: a follow-up study -1P Bonjour, They Chovaiey, Patek Ammann, O Sian, R Rzzll ‘Summary ‘Backgyouna Calcium supplement adoleecenoa increases bone mass acer. Whsther this bone porists aller discontinuation of Supplementation ‘© not know. We aresousy showed favourable effect of mientacted. calm prospate Feorgoratod in various fooda tn accumvaation of Bone tient tess yearns go. Ye ea Teper te reat ‘of flow say uncertakor more tan 3 years ee the end of eum supplementation fon curing cenaod ana Methods Arivopametie and oone wanablee wore measured in 116 of the 144 gis whose cata had been ‘Sonios a the eed at the supplemertaon pera. The fSecos ane te follomep measurement woe 2% years, ‘Neal bene mioerat density was measured by duatanerey {Eeayabsonsiomaty atthe same tx seletal sites a= ose ‘studies suring th intention shase, Fnngs We were abe to omeasue 62 and 54 ts of te Chleomeupoiomented and pacebo groups, respecte The increase fom. bateine nthe. wai ean one ‘ener dnsiy of the sir skeletal ses wos. Mien Egnticant(alcurspplemented. group 79" ma/e™ {SE 8) vz placebo group 404 me/om (7) p=0032). 4 Stunner ctrenonin four or oe auoiente gap wr aco Seen wih respect to sn bore miner eter, Fuvoal matron" eet "seem fo. eecoutt tre Focorsee derenes Interpretation Our raeutssuggct that the frm of mil friracted calcium phosphate taken curing the prepators| Derod can meaty the Uajectory of bane mass growth and Eaune a longtandingievnace in hana mast Se ‘which its Beyend the ond of supplementation. Lancet 2001; 366: 4208-12 Dano ave Baas (WHO Calaonsing Got or ‘emeperst and Son Dane), Depress ase Media tno Waco Mon, Bape ot adler, enya Bae tnd a PB conepondnce te: a? Berar Oran of Bone senses, sxc tara eace nea vps, Faz (Semi caro sigh 1208 SOGEPS Documentation GE Introduction “Te bone mniceral mass hat accum ates atthe end of ‘he growth pened i human beings the so-alled peak bone mass a major dererminunt of me nse of ontoporotic fractures ia later Lit” Dusig. grow, Steal of bone miners) tase walnly sesue om Imereases i bone sae, wrth very mall “hanges i volumetric bone desay.® Like tending hug, bone Comesponding £0 a specie percent le or SU) (Z score) ‘rom the mean” This development Js egatded a the ‘Couesioa of gcoute factoes that evcmtaaly determine intenndividual vanabiity m peak bvne mast, However result of avers! odier “have vuggesee that the Creitctory af bone cunens! mare snd stamlng” height might be shifted to ditarent percentile or Z vcore io ‘response to modieations ip enviror mental tators such {physical exercine eal or "tama D intakes ‘Burag childaood sad adolescenre, supplementeion of dietary caleuen increases areal bone mineral deasiey, 4% shown in. double-blind, placeho-contlled intez- ‘enti tala In thee tn, cecum mapplementaion swat provided ip variour salt font atch as cars ‘alate carbonate alae,“ carbcnate combined with ‘uconolaetate," oF phosphate fort mk cxreet” Ta nother prospective concolled studs, a positive ect 09 one-mineral mass war seen titer mie sopple- ‘cera of bone mince) wats seen

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