TOMAS CLAUDIO COLLEGES

Morong, Rizal
BASIC EDUCATION DEPARTMENT
SENIOR HIGH SCHOOL
SY: 2018-2019

FOURTH PRELIMINARY EXAMINATION IN GENERAL BIOLOGY 2

NAME: SCORE:
YEAR & SECTION: DATE:

I. VOCABULARY
Directions: Using the Across and Down clues, write the correct answer in the numbered grid below.

3.
2. 4.

1.

5.

ACROSS Down

1. An alternative form of a gene. 3. A trait or character that appears on an

2. This refers to the external appearance individual
of an individual as influenced by its genetic 4. A grid system used to determined the
make up. probable outcomes of the experiments
5. It is the genetic make up of the combination in cross breeding.
of genes of an organism.

II. MULTIPLE CHOICE

Directions: Read and analyze the statements carefully. Choose the letter of the best answer on the
space before the number.
6. Who was the first person to study heredity scientifically?
A. Gregor Mendel C. Reginald Punnett
B. Thomas Hunt Morgan D. Albert Einstein
7. Most sex – linked genes are found in the .
A. Y chromosome C. YY chromosome
B. O chromosome D. X chromosome
8. Hemophilia is a genetic disorder that is .
A. Sex – linked C. fairly common
B. Sex influence than in men D. more common in women
 9. Which parental pair could produce females with color blindness?
A. homozygous normal mom, affected father
B. affected mother, normal father
C. Heterozygous normal mother, normal father
D. Heterozygous normal mother, affected father
10. When cells contain three copies of a chromosome, it is called a .
A. chromosome deletion C. chromosome translocation
B. trisomy D. Multiple Allele
11.Down syndrome results from a/an .
A. extra chromosome C. chromosome deletion
B. chromosome translocation D. missing chromosome
12. Refers to a males inability to cause pregnancy in a fertile female due to deficiency in the
semen and semen quality.
A. Y – linked inheritance C. Y chromosomes infertility
B. X – linked inheritance D. Sex – linked inheritance
13. It is small and doesn’t contain numerous genes.
A. Y – linked inheritance C. Y chromosomes infertility
B. X- linked inheritance D. Sex - linked inheritance
14. It is inherited in both males and females and never transmitted from father to son but
from father to grandson.
A. Y – linked inheritance C. Y chromosome infertility
B. X – linked inheritance D. Sex – linked inheritance
15. are those which are associated either with the X or the Y chromosome.
A. Y – linked inheritance C. Y chromosome infertility
B. X – linked inheritance D. Sex – linked inheritance

III. IDENTIFICATION
Directions: Read and analyze the following statements carefully and identify the words being
described. Choose your answer from the word pool below and write the letter on the space provided
before the number.
16. This type of mutation is a change in one DNA base pair that results in the substitution of
one amino acid for another in the protein made by a gene.
17. a change in one DNA base pair but instead of substituting one amino acid for another it
altered DNA sequence prematurely signals the cell to stop building a protein.
18. It changes the number of DNA bases in a gene by adding a piece of DNA.
19. It changes the number of DNA bases by removing a piece of DNA.
20. It is a permanent alteration in the DNA sequence that make up a gene, such that the
sequence differs from what is found in most people.
21. It occur at some time during a person’s life and are present only in certain cells, not in
every cell in the body.
22. It inherited from a parent and are present throughout a person’s life in virtually every cell
in the body.
23. It consists of a piece of DNA that is abnormally copied one or more times.
24. It shifts the grouping of these bases and changes the code for amino acids.
25. A mutation that increases the number of times that the short DNA sequence is repeated.

A. Nonsense mutation E. Hereditary mutation I. Translocation

B. Deletion F. Gene mutation J. Repeat expansion

C. Missense mutation G. Inherited mutation K. Frameshift mutation

D. Insertion H. Acquired mutation L. Duplication

IV. MATCHING TYPE

Directions: Match column A with the correct answer on Column B. Write the letter of your answer on
the space provided before the number.

A. COLUMN A COLUMN B
26. It is a chromosomal disorder caused by
the presence of all or part of an extra chromosome 18. A. Huntington’s Disease
 27. An extremely rare genetic disorder occurs
due to the presence of the anomalous extra B. Patau Syndrome
isochromosome 12p.
28. A chromosomal abnormality in which some
or all of the cell of the body contain extra genetic material C. Edward’s Syndrome
from chromosome 13.
29. It is caused by the spontaneous deletion of D. Pallister – Killian Syndrome
26 – 28 genes on chromosome #7.
30. It is an inherited, degenerative brain disorder
which results in an eventual loss of both mental and E. William Syndrome
physical control.

B. COLUMN A COLUMN B
31. It is an excessive bleeding due to absence
of a protein necessary for blood to clot. A. Webbed Toes
32. Presence of long hairs on the rim of the
pinna or the outer ear. B. Hemophilia
33. The skin is covered by rough, bristly scales
except the head, face, palms, and soles. C. Parkinsonism
34. Degenerative disorder of the CNS
characterized by the lack of dopamine in the brain. D. Hypertrichosis of the ears
35. Presence of web – like connections
between 2nd and 3rd toes. E. Porcupine man

V. PUNNETT SQUARE
Directions: Create a Punnett square to predict the Genotype, Phenotype for the following sex –
linked problems.

36 – 40. A woman is heterozygous for normal and hemophilia alleles has children with a normal man.
Both parents have normal blood clotting, but the mother is a carrier. What is the chance of their sons
and daughters having hemophilia?

41 – 45. A colorblind man marries a female who is a carrier for colorblindness. What is the probability
that they will have a child who is colorblind?

VI. ESSAY
Directions: Through the use of your critical analysis, answer the question briefly. Make your writing
legible as possible.

RUBRIC POINTS
Relevance 2
Content 2
Penmanship 1
46 – 50. Gregor Mendel used pea plants for his experiment and discovered the fundamental laws of
inheritance. Thomas Hunt Morgan discovered the mutation in the fruit fly, Drosophila melanogaster.
Why do you think scientist and geneticist uses tiny organism like fruit fly and pea plants? Why don’t
they choose something larger?

Prepared by:

MRS. ROSE – ANN G. HILAO

Teacher

Checked by:

MR. RODOLFO G. HERNANDEZ, JR.

SHS, Coordinator

Approved by:

MR. DINDO C. PUNZALAN

Principal