Past questions -2

Questions and Answers:

1. Patient is on Propranolol, having CNS side effects of Beta-blockers. What can be

done?
Ans: Selection of Atenolol because it doesn’t have lipid solubility so can’t cross Blood
Brain Barrier.
2. Phenytoin Loading Dose
3. Donepezil- what is the maximum dose?
4. Patient is on Digoxin and sudden increase in Digoxin level. What is the possible
reason?
Ans: Dig + Verapamil Drug Interaction
5. Which one of this has no drug interactions?
Ans: Omeprazole + warfarin
6. Heparin overdosing? What should be used?
Ans: Protamine
7. Renal failure? What are the possible symptoms?
8. Case profile. Patient is going to have dental surgery.
Ans: Should be treated with penicillin before surgery.
9. Penicillin’s normal allergy. What antibiotics can be used?
Ans: Cephalexin. If it is anaphylactic then Beta-lactams must be avoided.
10. Which one of the following is the side effect of Levodopa ....Ans. Hypertension.
11. The clearance of Lignocaine has been decreased...Ans. Due to reduced blood supply
to the liver.
12. Which one is not a side effect of aminoglycosides?...Ans. Anaemia with increased
iron in blood. Because it is not affected by G6Pdeficiency.
13. Which one is inert plasma expander... Ans. Dextran
14. What is Absolute Bioavailability?
15. Hypothyroidism.....wht are the symptoms?....Ans. Myxoedema.
16. Betaxolol can make worse which one of the cardiac condition........Ans. aortic
stenosis.
17. Which is not included in tablet testing.....Ans. Tablet Uniformity
18. One case study and the question was about when should the Na solution to be taken
for gastric emptying?.......Ans. One day before colonoscopy.
19. Monitoring of Heparin............Ans. APTT
20. What is Selegiline......Ans. MAO-B
21. Atropine toxicity.............
22. Absorption is faster in which part of GIT?.... Ans. Small Intestine
23. Radiating Substance......what is the half life. .....Ans. It follows 1 st order kinetics. So
calculate according to that.
24. Ginko Biloba is not used for which condition?
25. Drug of Choice for Cellulitis. Can’t take penicillin. What are the options? .......Ans.
Clindamycin.
26. Clostridium Difficille infection related question
27. Rifampicin monitoring.
28. In Bipolar, which drugs are not used. Ans. Benzos because it increases GABA.
29. In Epilepsy, what is the mechanism?.....Ans. Decrease in GABA so we use all the
drugs which increases GABA.
30. Increase in DOPA, decrease in Acetyl Choline............Ans. Tardive Diskinesia.
31. Polymorphism.....Which is not a property of it?...... Ans. X-ray.
32. Amphotericin causes wht?..........Ans. Decrease in K+ level.
33. Oral antifungal treatment..... Ans. Fluconazole
34. Orally Unstable.....Ans. Nystatin
35. ACE Inhibitors side effects.
36. Drug of Choice for diabetes. Ans. ACE/SARTANS
37. MOA of Insulin.....Ans. Increase glucose uptake.
38. Moist heat sterilization is better than dry heat.
39. Opioids doesn’t cause what?..Ans. Diarrhoea.
40. Some skin conditions and symptoms......which is tht... is tht a drug allergy, stven
jhonson syndrome or anything else?
41. Grandular fever.......which should not be used? Ans. Amoxycillin.
42. Chloramphenicol......... Renally cleared., so dose reduction is necessary.
43. Hyponatremia.........is side effect of Carbamazepine.
44. Vit-D is not destroyed by wht? Ans. Sunlight.
45. Case is given and asked use of phosphate buffer.
46. Side effect of Daunorubicin........Cardiotoxicity
47. Classification of Anti-HIV drugs. X drug belongs to which class?
48. Treatment of Varicella Zoster Virus..Which treatment duration is correct? Eg. 4 days,
21 days, 7 days, 18 days.......Ans. 7 days.
49. Midazolam.........Ans. Used for Anaesthesia.
50. Dobutamine.........Used in HF.
51. Dose of Hydrocortisone in COPD.
52. Cholinergic Side effects........which one is not?
53. Normal fasting blood glucose level....Ans. 3-6mmol/L
54. H2 Receptor antagonist + Ketoconazole.......decreases absorption from gut.
55. Metoclopramide......which one of the following is not a side effect?
56. Coal tar should not be used for some UV treatment. Becoz it causes photosensitive.
57. Which one antipsychotic has the least extra pyramidal side effects?
58. Drug absorption is mainly pasive absorption.
59. Opiods.....which one is not a side effects of opioids.
60. Which one is not an isomeric mixture?
61. Urinary infection.......drug of choice is augmentin....for women.
62. Which one is a skin condition? All options were incorrect like. OA, RA, OP, Gout. One
left.....which was correct.
63. Which one doesn’t cause liver damage. Eg. Alcohol, PCT.
64. Addison’s disease.............its a disease of adrenal cortex.
65. Some calculation of stock solution
66. Insulin overdose .......symptoms.
67. Some graph is given........calculate clearance...
68. Acne....name of the organism
69. Whooping cough.........2 questions.
70. H.pylori infection......
71. ACE inhibitor..........mech of action
72. Migraine...........2 questions
73. Which medication should be given with food?
74. Sympathetic/parasympathetic question
75. Asthma.......is wht?
76. Which doesn’t have active metabolite?...Aspirin
77. Some question on Heloperidol
78. TPN doesn’t contain Vit-K.