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Asthama and COPD

LABA Efformetrol 6mcg efformetrol+budesonide


12mcg eformerol + budesonide

SABA Salbutamol(albutrol)

used in exercise induced


exercise induced
asthama and preterm lanour
MDI
community

hospital

DPI 5mg every 15-30 mins


IV injection 200-300 mcg over 1min
IV infusion 200mcg over 1 min

IM/SC 500 mcg. Repeat every 4 hrs

Salmetrol maintenance therapy in ex induced combination with fluticasone

Terbutaline SC route preferred in acute asthama

initial 10mg/kg max 300mg. If that is


Theophyllines well tolerated, 900mg max dose
first increment - 13mg/kg. max 450 therapeutic range - 10-
mg 20mg/L
second increment 16mg /kg.max
600mg
100mcg beclometasne-=200mcg
corticosteroids budesonide(croup)=100mcg
fluticasone

Codeine 15-30ml 4times daily


avoid contact with rubber
3-4 ml 2-6 hrs and metal . Rapid
acetylcysteine inactivation
take evening dose 2-3 hrs
mannitol cystic fibrosis befre bedtime
dornase alfa
adjunct to extubation in preterm
Caffeine infants 20mg/kg-40mg/kg

usual 10-20mcg/ml higher


therapeutic range conc - 25-35mcg/ml. toxicity
>50mcg/ml
100-200 mcg(1-2puffs) 5-15 mins
before exercise

300-400mcg(4puffs) every 4 min till


the ambulance arrives
8-12 puffs 15-30 mins

Asthama: 2 inhalations 25mcg


salmetrol with 50,125 and 250mcg
fluticasone

COPD:2 inhalations twice daily. 25


mcg salmetrol with 50, 125 and
250mcg fluticasone
1mg caffeine base = 2mg caffeine
citrate

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