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Glucose Ribose-5-P Metabolic Map


Pentose Phosphate Pathway
Lipids Carbohydrates Proteins

Glucose 2 Pyruvate Glycogen
(Triacylglycerol=Triglycerides) NH 3+ •
• •

(TAG)

Glycolysis •

so

COO -

Glucose Glycogen Glycerol
(3c)
Glucose
(6c)
Ribose-5-p 0 •

TAG ABBA ^

NADP+ NADPH i

Gly
Glycogenesis BABA
Fatty Acids cer
ol S Gluconeogenesis Gluconeogenesis o -ketogluterate
(16c) y nth
od
Glycogen Glucose esis Fructose-1,6 Bp Keto Acids
"

s
Amino Acids
(6c)
Muscles H
Glycogenolysis - OOC—C—C—C
DHAP G3AP(3c) NH 3+—C—COO -

Fa
O a

Lactic Acid

t
TAG Glycerol + FA (3c)

ty
R

B-

A
Transaminases (alanine, Aspartate, Glutamate)

cid
Ox
Lipolysis G3AP Phosphoenol Pyruvate

Sy
ida

nt
(PEP) +

hes
ion
FA + Glycerol

i
TAG

s
Pyruvate New Amino Acid New Keto Acid
Cholesterol Pyruvate

(3c) (3c) (Glutamate) (Pyruvate, Oxaloacetate, -ketogluterate) a

Lipogenesis Bile Salts


Steroid
Cell
Membrane Transition
Stage
Hormones

Acetyl CoA Cholesterol Acetyl CoA Acetyl CoA Glutamate
(2c) (2c) Dehydrogenase
Cholesterol Synthesis G
OAA G
OAA NH3 Ammonia (Toxic)
- Gluconeogenesis

Acetyl CoA Ketone Bodies Krebs Urea Cy Urea

:
Cycle - MAKE ATP o -ketogluterate cle
(Less Toxic)
Ketone o -KG o -KG
Ketogenesis Bodies
(Acetoacetate, b-hydroxy butyrate) NADH FADH 2 NADH FADH 2
A.A. + Keto Acid Keto Acid + A.A. Kidneys

Transamination
ETC Odd Chain FA (17c)
A.A.
Glutamate (A.A.) Keto Acid

:
Lactic Acid Glucose
Glycerol
NH3
Oxidative Deamination Gluconeogenesis

Ketone Bodies Acetyl CoA ATP


Ketolysis

Metabolism Metabolic Map | Proteins


f) I

* .

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