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Factors Associated With Development of Anaemia in Children Below 5 Years in Thika Level 5 Hospital
Factors Associated With Development of Anaemia in Children Below 5 Years in Thika Level 5 Hospital
BY:
D/NURS/19005/3809
Po Box 30195-00100
Thika.
July, 2022
i
DECLARATION
I hereby declare that all the work presented in this study is my own and has not been submitted
in partial fulfillment of a Diploma in Community Health Nursing in this or other institution of
higher Learning.
Signature……………………………….
Date……………………………………….
Signature………………………………….
Date…………………………………………
ii
DECLARATION
I hereby declare that all the work presented in this study is my own and has not been submitted
in partial fulfillment of a diploma in community health nursing in this or other institution of
higher learning.
iii
ACKNOWLEDGEMENT
I give thanks to almighty God for giving me good health and the will to undertake and
accomplish my research study.
Special thanks go to my course lecturers for their guidance and knowledge which they impacted
in me. Not forgetting my beloved parents who supported me financially through the course, May
almighty God bless them abundantly.
I wish to the management of Thika Level 5 hospital for allowing me to carry this study in their
facility.
I also thank the medical doctors, nurses in pediatric ward at Thika Level 5 hospital.
I also thank all my collogues for their moral support and encouragement throughout my study.
May the Almighty God bless them all.
iv
v
TABLE OF CONTENTS
DECLARATION.............................................................................................................................ii
DECLARATION............................................................................................................................iii
ACKNOWLEDGEMENT..............................................................................................................iv
ABSTRACT....................................................................................................................................x
2.1 Introduction................................................................................................................................4
2.3.1 Age..........................................................................................................................................5
2.3.2 Gender.....................................................................................................................................6
3.1 Introduction................................................................................................................................8
vi
3.4 Study Population........................................................................................................................8
4.1 Introduction..............................................................................................................................12
4.2.4 Occupation............................................................................................................................15
vii
4.2.8 Gender of the child...............................................................................................................18
5.1 Introduction..............................................................................................................................23
6.1 Conclusion...............................................................................................................................25
6.2 Recommendations....................................................................................................................25
REFERENCES..............................................................................................................................26
APPENDICES...............................................................................................................................27
Appendix 1: Questionnaire............................................................................................................29
Map of Africa................................................................................................................................33
Map of Kenya................................................................................................................................34
viii
LIST OF TABLES
Table 1: Age of the respondents....................................................................................................14
Table 2: Age of the child...............................................................................................................18
ix
LIST OF FIGURES
Figure 1: Relationship of the care givers with the child................................................................15
Figure 2: Marital Status of The Respondents................................................................................16
Figure 3: Occupation.....................................................................................................................17
Figure 4: Number of children........................................................................................................18
Figure 5: Gender of the child.........................................................................................................19
Figure 6: Gender of the child.........................................................................................................20
Figure 7: Definition of anemia......................................................................................................21
Figure 8: Definition of anemia......................................................................................................22
Figure 9: Infections Associated with Anemia...............................................................................23
Figure 10: Infections Associated with Anemia.............................................................................24
x
ABSTRACT
Introduction: The purpose of this study was to determine the factors associated with
development of anemia among children under five years admitted in pediatric ward at Thika
Level 5 Hospital. Anemia is a major concern both globally and in the Africa continent. It is
ranked as the third leading cause of both morbidity and mortality to the under-five year’s
children. It is associated with many factors like, knowledge, social economic and infections.
Methodology: A descriptive a quantitative Cross-sectional research design was used. The tool
used was structured questionnaire. Simple sampling was to use on the large numbers of children
coming in at the same time. The researcher had to use the hospital randomly pick caregivers
whom were interviewed. The collected data was analyzed using Microsoft excel Microsoft word
and presented using tables, pie charts and bar graph.
Findings: According to the study, majority of children had anaemia are aged than one year
(38.5%) and between two years and three (38.5%). According to the findings most caregivers
(57.7%) they define anaemia as reduced blood supply in the body and remaining percentage
(42.3%) understood anemia as loss of blood. 40.4% of them said of anemia is causes of anemia is
poor diet, followed 25% to bleeding, and the rest 17.3% each believed that anaemia is caused by
infection such as helminthic and chronic diseases such as cancer respectively. According to the
study, most infections are associated with anemia in under-fives were worms (36.5%), followed
by sickle cell (23.1%) and cancer (23.1%) and (17.3%) malaria.
Conclusions: Children aged below 5 years, those living I low socio-economic status and those
who take a diet not enriched with iron are not at risks of developing anemia, thus improving
socio-economic status, prompt treatment infection and deworming under five years would
prevent the risk of anemia.
xi
CHAPTER ONE: INTRODUCTION OF THE STUDY
1.1 Background of Study
Anaemia is defined as reduction of Red Blood cells (RBC) volume of hemoglobin concentration
below ranges of values occurring in healthy person
Table 1.1 shows ranges from hemoglobin and hematocrits values by age of well shed children
Anaemia is á highly frequent disease worldwide. It affects Individuals in all stages of life
although pre-school children and women are the most heavily affected. In pre-school children,
there is rapid growth which increase demand of iron, if micronutrients balance is negative, the
disease can develop. Various factors are associated with the occurrence of anaemia amongst
which are genetic causes; parasitic infections and other micronutrient deficiencies. in addition,
low consumption of iron-rich foods and high intake of iron absorption inhibitors iron chelating
substances (Horne et al, 2017)
Socio-economic factors such as poor housing, crowding and poor education level pre dispose to
illness in parts of Asia and Latin America. Other's socio-cultural beliefs may be important risk
factors of anaemia such as delayed treatment – seeking and inappropriate medication both which
are common among people of Africa (Tanzania) (Mwenesi et al 2016).
1
1.2 Problem Statement
Up to 20% Of American children and 80%of children in developing countries become anemic at
same point during their childhood and adolescence. Iron deficiency is common cause in children
but other forms of anemia including hereditary blood disorders can also cause anemia in
population (Brutanek et al 2015).
Under five years children hospitalized in Thika Level 5 Hospital, most of them suffer from
anaemia and some of the contributing factors are severe acute malnutrition and Iron deficiency.
Also, they will be able to curb those factors in order to reduce the number of admissions of those
children with anaemia in pediatric ward. Community also will be educated by the health worker
to get knowledge on the factors associated with anaemia to them under five children and improve
health status.
Under five children will be prevented and managed and reduce hospitalization and promote
developmental status.
2
1.5 Study Objectives
1.5.1 Broad Objective
To establish the factors associated with the development of anemia in children below five years
of age.
3
CHAPTER TWO: LITERATURE REVIEW
2.1 Introduction
Anaemia refers to a condition that result from a decrease of blood cells or the normal quantity of
hemoglobin in the blood. However, it can include decreased oxygen- binding ability of each
haemoglobin molecule development in some other types of haemoglobin deficiency (sia et al
2013)
Anaemia is most common disorder of the blood. There are several on kinds of anaemia produced
by a variety underlying causes. Anaemia can be classified variety of ways, based on the
morphology of RBCs, underlying enological mechanisms and discernible clinical Spectra, to
mention a few.
The main classes of anaemia include, excessive blood loss (acutely such hemorrhage or
chronically thin low-volume loss), excessive blood destruction or deficient red blood cells
production effective haernetopoiesis) (Vinay et al 2015)
Anemia in under five is a public health problem worldwide data from World Health Organization
(WHO), shows that the anemia prevalence among children aged 16-59 years is 42.6% globally
and maximized in Africa (62.3%).
The cause of anemia is multi-functional, including the shortage of hematopoietic, material iron
deficiency is a common cause of anemia in children under five years (Juan Xiao et al, 2015)
Childhood anemia will adversely affect the health of children Including physical development,
and may cause eversible clamaqes to motion, cognitional and behavioral development. The age
from 0- 5years old critical period for children's growth and development and it is also a high
group for anaemia. There are factors that associated with development of anemia under fires
which are;
4
months (87.5%) and had a diagnosis of severe anaemia (75.0%) according to the World Health
Organization definition: Maternal anemia reported by 67.500 of mothers.
Mother reported that maternal anemia (17.5%) and feeding practices (32.5%) are known
contributing factors to anaemia in children. Mother's reported anaemia could be prevented
(55.0%) and cured by herbal preparation (47.5%).
In addition, some mothers indicated that anemia was caused by witchcraft (2.5%) and eating
lemons (2.5%). Severe anaemia was high among the studied population which aligned with their
hospitalization status finding suggested that potential gaps in control and management of
anaemia in children possibly related to low awareness or incorrect knowledge on Information
about anaemia in children by me caregivers. There is also Imperative for culturally and
translation and exchange with mothers in order to impact on the prevention and control of
anaemia in children in Tanzania (Pammia Petruko et al 2014).
A study done at Sylvanus Olympia teaching hospital in Lomé shows that forty mothers had never
about any information about anaemia. Health personnel was the main source of mother's
Information (29%), mass media of mother’s information source (radio 5%, television 3%)
The decreased blood in the body is the most given definition from the mothers 44%. Malaria
(20%) and malnutrition (19%) were the main causes cited by the mothers. iron deficiency
mentioned by 36 of the mothers. Palmore plantar pallor 32% was the clinical sign best known by
the mothers. (B. Benoist, E, 2012)
Most of the mothers (90%) had never assist to an information education and communication
message about anaemia prevented. When their child had anaemia, 25 mothers (65.86%) took
their children to health facilities while fine mothers (13-2/2 had given a treatment. It concluded
that anaemia was not known by the mothers of under five children, that its causes and treatment
(Fidele Colman Dossou et al 2016)
5
2.3.1 Age
Infants are at high risk because milk diet contains very small amounts of Iron. Human breast
milk, for example iron, only about 0.3mg/l of iron. cow’s milk contains twice as much as human
breast milk bio availability. Children especially the early years of life, have incredible dietary
iron needs accompanying expansion of blood volume (Cartman et al 2013)
Infants’ boys may have ten times more risks than baby girls. In general, full term breastfed
infants have enough iron stores for their 6months of life. After that, they must rely on other
sources of iron stopping breast feeding too early or using formula that is not iron fortified is
associated with deficiency anaemia (Cartman et al 2013)
According to the results from the National Nutrition survey (NND in Mexico, carried m 2009
[NN-09), the highest prevalence was found in children between ages of 12 and 24 months
(Villalpando et al 2013)
Children under 2 years have increased nutritional requirements because of their growth spurt,
which often leads to a negative nutrient balance. (Agostoni et al 2002)
2.3.2 Gender
Boys’ infants are affected more with severe anemic than girls’ infants. This is because of the
higher growth rate among boys during growth stages results in higher anaemia prevalence, as
their bodies demand higher amount of iron, which cannot be supplied by the diet as study results
done in Burma, Benin and Mali (Sankar Goseumai, Kishore k. Das et al 2015)
Even in the United States iron deficiency is the most prevalent nutritional deficiency. It is for
highly association with poverty. People in lower socio-economic groups having double the risk
of those who are middle upper class. In a study of low-income children six months was nearly
18% children two. It should be noted however, that children, group can develop deficiency
anaemia. (Britanek 2017).
A study carried out in Indian showed that low haemoglobin concentrations in rural Indian
children primarily result from micronutrient (especially on deficiencies attributable poor
6
nutritional intake compounded by adverse socio-economic conditions and food security,
Haemoglobin level was primarily associated with iron status in Indian toddler, how maternal
haemoglobin level, family health and food security also important factors. strategies for
childhood. anaemia must include optimized iron intake should simultaneously address material
analgia, poverty food insecurity (slenderer et al 2012)
Conditions associated with anaemia infection and chronic disease include such diverse disease as
chronic bacterial endocarditis, osteomyelitis, I wishenite rheumatoid arthritis, rheumatic fever,
Crohn’s disease and ulcerative colitis. Chronic renal failure may produce a similar anaemia
because of causes reduced levels of erythropoietin, the hormone that stimulated the protraction of
red blood cells in the marrow treatment of the underlying disease prevent or the anaemia chronic
bone can reverse the anemia chronic disease like Crohn’s disease are different to treat and
patients may exhibit intermittent anemia that varies with their conditions (Kumar et al, 2010)
Disease associated with ACD and information, the chronic disease that are associated with this
process include;
autoimmune disease example includes systemic lupus, every thromatus, rheumatoid arthritis,
polymyalgia rheumatic and inflammatory bowel.
Health failure. Many patients with a higher risk of death in patients with heart failure. It may
be caused by lack of nutrients from food. Heart failure can also cause a backup of fluid.
Hepatitis C; the liver cirrhosis associated with hepatitis C can reduce the production of red
blood cells. Gastro intestinal bleeding, may also contribute to blood loss.
Long term infections; examples include chronic or recurrent urinary tract infections and
osteomyelitis.
7
HIV/AIDS; the inflammatory process associated with AIDS can adversely affect EDO levels
and red blood cells production.
This chapter deals with background of the study area, study design, definition of variables,
inclusion and exclusion criteria, study population, sampling procedure, sample size, data
collection tools, data collection procedure and study limitation.
The Study Will Be conducted in Paediatric unit of Thika Level 5 Hospital, located in Thika
town, Kiambu County Kenya. This the main county hospital in Thika with a well paedriatics
ward which offers all services concerning children but also medical and surgical services include
preventive, promotive and rehabilitation services are offered.
The study will be a cross-sectional study. It will be carried out to determine the associated
factors of anemia in children below 5 years.
The study will include all children less than 5 years of age appropriately 200 who admitted in the
paedriatics ward at TL5H in July 2022.
8
3.6 Study Variables
3.6.1 Independent Variables
Children below five years of age with anemia.
N= Z2PQ
d2
Where,
n= the desired sample size (if target population is more than 10,000)
P= the population in the target population estimated to have characteristic being measured taken
as 0.5
Q= I-P
D =level of statistical significance set at 95% is confidence level with an error of 0.05
Therefore
n= (1.96)2(0.5) (0.5)
(0.0025)
n=384.16
9
If the target population is less than 10000, the required sample will be smaller. In such cases,
final sample estimates are calculated using the following formula:
Nf= n
(1+n)/N
Where nf=the desired sample size where the population is <10,000
n = the desired sample size when the population is > 10,000
N= The estimated number of populations is taken as 8,000
Nf= 384
(1+384)/200
Nf = 384/2.92=131.5
Therefore nf=132
Due to limitation of time the researcher will not be able to cover 132 subjects and thus only
40% of the sample size will be used to be the respondents
Hence:
40% of 132 respondents
40/100 x 132=52.4
Sample size = 52 respondents
3.8 Sampling interval
S1= total population/ sampling size
=200/132
=1.515
=2
So, every 2nd respondent will be selected
10
3.11. Pre -Testing Questionnaire
This will be done using respondents from TL5H. The researcher will come up with 5
questionnaires for pre testing so as to achieve validity and detect any irrelevant sot that early
possible corrections may be made before actual survey is done pediatric ward.
The Questionnaire will contain clear instructions from the respondents in order to ensure that
each ethical consideration is observed.
11
CHAPTER FOUR: STUDY FINDINGS, DATA ANALYSIS AND
PRESENTATION
4.1 Introduction
This chapter involves analysis and presentation of findings from data collection which are
presented in form of charts tables and graphs.
From the above table, 34.6% of the respondents were aged between 26-+30 years, 23.1% above
30 years. 21-25 (19.2%), 16-20 years and 3.8% before 15 years. This shows that majority of the
respondents were between 26-30 years
12
4.2.2 Relationship of the care givers with the child
9.60%
13.50%
76.90%
The above pie chart (76.9%) 40 respondents are mothers, 13.5% (7 respondents) guardians and
9.36% (5 respondents) are fathers.
13
4.2.3 Marital Status of The Respondents
13.50%
7.70%
50.00%
28.80%
From the chart above 50% (26 respondents) were married, 28.8% were single, 13.5% (7
respondents) were divorced and 7.7% (4 respondents) were widowed. From the above shows that
majority of the respondents were married 50% (26 respondents) clients.
14
4.2.4 Occupation
Figure 3: Occupation
60.00%
50.00% 48.10%
40.00%
30.00% 28.80%
23.10%
20.00%
10.00%
0.00%
Occupation
15
4.2.5 Number of children
5.80%
11.50%
32.70%
9.60%
40.40%
From the above chart, it shows that majority of the respondents have two children (40.4%),
followed by one (32.7%), four (11.5%) three (9.6%) and five or more.
From the above table 38.5% of the age of the children are < 1 years, 38.5% between 2-3 years
and 2.3% between 3-5 years.
16
4.2.7 Gender of the child
40.40%
59.60%
Female Male
From the chart above majority of the children are male (59.6%) and 40.4% are female.
17
4.2.8 Gender of the child
13.50%
53.80%
32.70%
18
4.3 Knowledge of caregivers on anemia
4.3.1 Definition of anemia
42.30%
57.70%
The study revealed that (59.7%), most of the caregivers understand anemia as having reduced
blood in the body and the rest (42.3%) understood it as loss of blood.
19
4.3.3 Cause of anemia
45%
40.40%
40%
35%
30%
25% 23%
20%
17.30% 17.30%
15%
10%
5%
0%
From the above graph, 40.4% of the caretakers knew causes of anemia as poor diet, 25% who
said bleeding, 17.8% infection such as helminthic and 17.3% chronic diseases such as cancer.
4.2.4 Source of information about anemia from the above chart majority of the caretakers got
information about anemia from health workers (36.5%), followed by mass media CTV, radio and
newspapers.23.1%, then social media such as Facebook, WhatsApp) 21.2% and lastly
community health volunteers.
20
4.4.0 Infections Associated with Anemia
19.20%
36.50%
21.20%
23.10%
Infections associated of anemia majority of them are worms 36.5%, followed by sickle cell
(23.1%) cancer (23.1%) and malaria (17.3%)
21
Figure 10: Infections Associated with Anemia
17.30%
36.50%
23.10%
The study revealed that majority of the respondent (36.50%) cancer while the least (17.30%)
were worms.
22
CHAPTER FIVE: DISCUSSION
5.1 Introduction
This chapter discusses conclusively the study findings in line with the study objectives data
collected.
5.2 Socio-demographic factors
According to the study, majority of children had anaemia are aged than one year (38.5%) and
between two years and three (38.5%). This concurs with 2013 study carried out in Mexico by
Villalpando and showed that the highest prevalence of anemia was found in children aged
between 12 and 24 months and most of them boys. This indicates that less aged male children are
at a higher risk of developing anaemia. (Villalpando 2012)
The findings of the study show that the usually children were (53.8%) breastfeeding. This shows
that infants are at high risk because milk diet contains very little amounts of iron, hence
predisposed to anaemia. This corresponds a study of 2013 done by cartman suggested that
infants to stop breastfeeding early and provided supplements to increase iron in the circulation
(cartman et al 2013),
majority of caregivers were mothers (34.6%) aged between 26 and 30 years. Most of them were
business people followed by (28.1%) government employment. The highest were (50%) married
and had two children (40.4%). This explains that the care givers' families in middle class living,
hence concentrate in more to their businesses rather than spending enough Time children, and
providing with required nutrients
5.3 Knowledge of caregivers on anemia
According to the findings most caregivers (57.7%) they define anaemia as reduced blood supply
in the body and remaining percentage (42.3%) understood anemia as loss of blood. 40.4% of
them said of anemia is causes of anemia is poor diet, followed 25% to bleeding, and the rest
17.3% each believed that anaemia is caused by infection such as helminthic and chronic diseases
such as cancer respectively.
There sources of information about anemia were led by health workers (36.5%), followed by
mass media (TV, Radio, Newspaper) (23. 1%), social media (Facebook, WhatsApp) 21.1%) and
least from community health volunteers (19.2%).
23
These findings concur with a study carried out by whenter in 2012 shows that causes of anemia
were poor diet intake of Iron and worms’ infestation in under five years.
5.4 Infections associated with anaemia in under-fives
According to the study, most infections are associated with anemia in under-fives were worms
(36.5%), followed by sickle cell (23.1%) and cancer (23.1%) and (17.3%) malaria.
24
CHAPTER SIX: CONCLUSION AND DISCUSSION
6.1 Conclusion
Children aged below 5 years, those living I low socio-economic status and those who take a diet
not enriched with iron are not at risks of developing anemia, thus improving socio-economic
status, prompt treatment infection and deworming under five years would prevent the risk of
anemia.
6.2 Recommendations
Deworming od children after every three months should be encouraged to the caregivers by
health workers. health talks should be arranged by health workers to advice caretakers on
prompt treatment of disease like malaria to avoid complications.
More emphasis should be put on parents/guardians bringing their children to hospital to
improve feeding practices on their children by giving them iron rich foods, such as meat,
fortified cereals, eggs, green vegetables and beans.
25
REFERENCES
1. Siamak T. Nabili et al 2013, Harrison’s principles of internal medicine 17 th edition, United
States.
2. Juan Xiao Et al 2015.
3. Zul Promji et al 2015: Anemia and plasmodium falciparum infections Among young
children in an holoendemic area, Bagamoyo, Tanzania.
4. Villalpando s et al 2013: prevalence of anemia in 1-2 years of age results from nationwide
probabilities survey.
5. Kumar, et al 2017, Robbins Basic Pathology page 432, 8th edition, Saunders Elsevier.
6. S. Bharati, M. Pal, S. Chakrabarty, and P. Bharati, “Socioeconomic determinants of iron-
deficiency anemia among children aged 6 to 59 months in India,” Asia-Pacific Journal of
Public Health, vol. 6, 2013.
9. International Institute for Population Sciences and Macro International (IIPS and Macro
Int.), National Family Health Survey (NFHS-3), 2005-06, Key Findings, International
Institute for Population Sciences, Mumbai, India, 2007.
10. T. Walter, I. de Andraca, P. Chadud, and C. G. Perales, “Iron deficiency anemia: adverse
effects on infant psychomotor development,” Pediatrics, vol. 84, no. 1, pp. 7–17, 1989.
11. Freedman, D.S, Thornton, J.C., Mei, Z., Wang, J., Dietz, W.H., Pierson, R.N. and Horlick,
M. (2004). Height and Adiposity among Children. Obese Res, 12: 846–853.
12. Frohlich, K.L., Potvin, L., Gauvin, L. and Chabot, P. (2002). Youth smoking initiation:
disentangling context from composition. Health & Place 8, 155–166.
13. Hien, N.N., Kam, S. (2008). Nutritional status and the characteristics related to
malnutrition in children under five years of age in Vietnam. J.
Public Health. 2008
14. Kabubo-Mariara, J. Ndenge, G.K. and Mwabu, D.K. (2009). Determinants of children’s
nutritional status in Kenya: evidence from demographic and health surveys.
.
15. Mamoun N. Homedia, S. Mabyou, M., Hussan, M., Muntasir, A., Salah, T and, Adam, I,
(2009). Prevalence, types and risk factors for malnutrition in displaced Sudanese
26
APPENDICES
Appendix I: Consent Form
Title of Proposal: You will be given a copy of the full Informed Consent Form
Significance of Study
This study is aiming to assess factors that are associated with development of anaemia in under
five years children. It will be useful to health practioners to know the factors that contribute
anaemia most in under five children admitted in Thika Level 5 Hospital.
Also, they will be able to curb those factors in order to reduce the number of admissions of those
children with anaemia in pediatric ward. Community also will be educated by the health worker
to get knowledge on the factors associated with anaemia to them under five children and improve
health status.
Under five children will be prevented and managed and reduce hospitalization and promote
developmental status.
Participant selection: We are randomly selected for interview mother with under five
children with anaemia in TL5H.
Benefits and Risks: There are no direct benefits for you as an individual but your involvement
will help understand factors associated with anaemia in under five children.
Voluntary Participation: Your involvement in this research is completely voluntary. You
27
may change your mind later and discontinue taking part even if you had agreed earlier. I
will keep everything you tell me confidential and I will not show anyone that it came from
you.
Appendix II: Permission Letter
28
Appendix 1: Questionnaire
Instructions
29
SECTION B: CHILD INFORMATION
30
Appendix II: Budget
Stationary
Pens 4 100
Pencils 2 20
Ream 1 500
Computer services
TOTAL 6520
31
Appendix III: Work Plan
Activity APR MAY JUN JUL AUG SEP OCT NOV DEC
Topic
Selection
Proposal
Writing
Proposal
Submission
Proposal
approval
32
Appendix IV: Maps
Map of Africa
33
Map of Kenya
34
Map of Kiambu County
35