CHEMICAL COORDINATION AND INTEGRATION

1. Endocrine glands are -

(a) Ductless glands whose secretions pour directly into blood .
(b) Have ducts and pour their secretions into blood directly
(c) Have ducts which straightaway pour secretions into target organs
(d) All of the above
2. Which of the following statements about hormones is I are correct?
I. Hormones are non-nutrient chemicals
11 . Hormones act as intercellular messengers
Il l. Hormones are produced in trace amount
IV. Hormones may be proteins, steroids, glycoproteins and bigenic amines
(a)All (b) I, II , Ill (c) IV (d) I, Ill
3. Wh ich of the following statements is false?
(a) Hormones provide chemical coordination , integration and regulation in the human body
(b) Hormones regulate metabolism, growth and development of our organs
(c) Besides hypothalamus, pituitary, pineal , thyroid , adrenal , parathyroid , thymus, etc., GIT, heart, kidney, etc also
produce hormones.
(d) Hormone can be used again and again like biocatalyst
4.

JSm.----- -+-D

r~l=f=t==-- F
(ln male)
The above figure is related with principal endocrine glands in human . Identify A to G -
(a)A- Pineal, B- Pituitary, C - Thyroid and parathyroid , D - Thymus, E-Adrenal, F-Testis, G-Ovary
(b) A - Pituitary, B - Pineal, C - Thyroid and parathyroid , D - Thymus, E -Adrenal , F- Ovary, G - Testis
(c) A- Pituitary, B - Pineal, C - Thyroid and parathyroid , D - Thymus, E - Kidney, F- Testis, G - Ovary
(d)A- Pituitary, B- Pineal, C - Thyroid and parathyroid , D - Thymus, E -Adrenal, F-Testis, G - Ovary

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 Chemical Coordination and Integration

5. Which of the following options is false?

(a) Invertebrates possess very simple endocrine systems with few hormones
(b) The hypothalamus is the upper part of diencephelon (part of fore-brain)
(c) The hypothalamus contains several groups of neurosecretory cells (nuclei) which produce hormones
(d) The hypothalamus produces releasing hormones, inhibiting hormones, oxytocin and vasopressin
6. Hormones have various regulating functions . Which of the following statements does not describe how hormones
function?
(a) Hormones act in very low concentration (b) Hormonesactatsitesdistantfromwheretheyareproduced
(c) Hormones are transported in blood (d) None of the above
7. Portal blood vessels connect the _ _ _ _ _ _ to the _ _ _ __
(a) Hypothalamus, brain (b) Hypothalamus, posterior pituitary
(c) hypothalamus, anterior pituitary (d) Anterior pituitary, posterior pituitary
8. Hormones released by the posterior pituitary (oxytocin and vasopressin) are produced in the-
(a) Anterior pituitary (b) Hypothalamus (c) Pineal (d) Thymus
9. Pituitary gland is regulated by -
(a)Adrenals (b) Pineal (c) Thyroid gland (d) Hypothalamus
1O._ Which of the following options is false?
(a) The posterior pituitary is under the direct neural regulation of the hypothalamus
(b) Somatostatin from the hypothalamus inhibits the release of growth hormone (GH) from the anterior pituitary
(c) GnRH from the hypothalamus stimulates anterior pituitary to release gonadotrophins
(d) None of the above
11 . Which of the following options is correct?
(a) Posterior pituitary is connected to hypothalamus by nerve fibres
(b) Anterior pituitary is connected to hypothalamus by portal vessel
(c) Posterior pituitary is connected to hypothalamus by portal vessel
(d)'Both a and b
12. The pituitary gland is located in a bony cavity called _ _ _ _ _ and is attached to _ _ _ _ _ by a stalk -
(a) Sella tursica, hypothalamus (b) Sella tursica, cerebrum
(c) Sella tursica, thyroid (d) Sella tursica, pineal

13. Pituitary gland

I
divided anatomically into

+
A
I
..
8
I (Posterior lobe)
Consists of I
+
I
.. Stores and releases

•
I
c
(anterior pituitary)
D
(Secretes MSH)
+
Oxytocin Vasopressin

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I Cllemical Coordination and Integration
Identify A, 8, C and D -
(a) A- Neurohypophysis, 8 -Adenohypophysis, C - Pars distalis, D - Pars intermedia
(b) A-Adenohypophysis, 8 - Neurohypophysis, C - Pars intermedia, D - Pars distal is
(c) A-Adenohypophysis, 8 - Neurohypophysis, C - Pars distalis, D - Pars intermedia
(d) A- Neurohypophysis, 8 - Adenohypophysis, C - Pars intermedia, D - Pars distal is
14. Anterior lobe of Pituitary gland secretes -
I. FSH, GH and LH
II. GH, TSH and prolactin
Ill. TSH, ADH & prolactin
IV. ACTH, TSH and oxytocin
(a) I and II are correct (b) II and IV are correct (c) I and Ill are correct (d) I, II and Ill are correct
15. Which of the following hormones is mismatched with the stated functions?
(a) ACTH - Stimulates the adrenal cortex
(b) Oxytocin - Stimulates water reabsorption by the kidneys
(c) Prolactin (PRL) - regulates the growth of mammary glands and milk production in them
(d) TSH - Promotes the synthesis and secretion of thyroid hormones from thyroid gland
16. Which of the following statements is correct about oxytocin (pitocin)?
(a) It stimulates smooth muscles contraction
(b) In female, it stimulates a vigorous contraction of uterus at the time of child birth
(c) In female, it stimulates milk ejection from mammary gland
(d)All
17. Which of the following are gonadotrophins?
(a) FSH + GH (b) LH + FSH (c) LH + GH (d)GH
18. Which of the following options is not true?
(a) In males, LH stimulates synthesis and secretion of androgens (Testosterone) from testis.
(b) In males, FSH and androgens regulate spermatogenesis
(c) In female, LH induces ovulation of fully mature follicles (graafian follicles), and maintains corpus luteum.
(d) FSH is produced in only male
19. The corpus luteum -
(a) Is found in forebrain of human
(b) Is formed from the remnants of graafian follicles after ovulation
(c) Secretes mainly LH
(d) Is found in testis
20. Match the Column I with Column II -
Column I Column II
((a) FSH I. Transported axonally to neurohypophysis from hypothalamus
((b) MSH II. Acts on melanocytes and regulates pigmentation of skin
((c) Vasopressin (ADH) Ill. Stimulates the growth and development of ovarian follicles ih female
((d) Pars intermedia IV. In human, it is almost merged with pars distalis
(a)A-111, 8-11 , C-1, D - IV (b)A-1 , 8-11, C-111, D - IV
(c) A - IV, 8 - 111, C - II, D - I (d) A- Ill, 8 - II, C - IV, D - I

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 Chemical Coordination and Integration

21 .

. i. ~

D
Observe the above diagrammatic representation. Identify A to 0- .

(a) A- Hypothalamic neurons, B - Hypothalamic artery, C - Posterior pituitary

(b) A- Epithalamic neurons, B - Hypothalamic vein , C - Pars distalis, 0 - Pars intermedia

~
( c) A- Hypothalamic neurons, B - Portal circulation , C -Anterior pituitary, O Posterior pituitary
(d) A- Hypothalamic neurons, B - Portal circulation , C - Posterior pituitary, D -Anterior pituitary
22. Pineal gland is located on -
(a) Dorsal midbrain
(b) Ventral midbrain
(c) Dorsal side of forebrain( d) Ventral side of hindbrain
23. Melatonin is a hormone secreted by -
(a) Pineal (b) Pituitary
(c) thymus ' I
(d)Adrenal cortex
24. Which of the following functions is related with melatonin -

(a) Influence on metabolism , pigmentation, menstrual cycle, our defensE? capacity

(b) Regulation of the 24-hour (diurnal) rhythm of our body (eg - sleep-wake cycle, body temperature) .
(c) Both a and b

(d) Does not oppose FSH and LH .·.

25. Observe the following figures . Identify A to 0 -

(a) A- Parathyroid gland, B - Isthmus, C - Trachea, O - Thyroid

(b) A- thyroid , B - Isthmus, C - Trachea , 0 - Parathyroid gland
(c) A - Thyroid, B - Isthmus, C - Larynx, 0 - Parathyroid gland A
D
(d)A- Thyroid, B- Corpus luteum, C- Trachea, 0- Parathyroid gland
26. Which of the following option is wrong? (Ventral side)
(Dorsal side)
(a) Thyroid gland is the largest endocrine gland

(b) Each thyroid gland is composed of follicles and stromal tissues

(c) Thyroid gland consists of4 lobes
(d) thyroid gland secretes T , T and TCT
3 4

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I Cltemical Coordination and Integration
27. Thyroxine (T4 ) or tetraiodothyronine and Triiodothyronine (T3 ), produced by the thyroid gland, are synthesised from
iodine and-
(a) Phenylalanine (b) Cholesterol (c) Tyrosine (d) Glycoprotein
28. Iodine deficiency in our diet results in _ _ _ _ _ and enlargement of _ _ _ _ gland, commonly called

(a) Hyperthyroidism, thyroid, goitre (b) Hypothyroidism, thyroid, goitre

(c) Hypoparathyroidism, parathyroid, goitre (d) Hyperthyroidism, thyroid, acromegaly
29. Which of the following function is related with thyroid hormones?
(a) They play an important role in the regulation of BMR
(b) They also support RBC formation
(c) They control the metabolism of carbohydrates, proteins and fat
(d)All
30. Match the Column I with Column II ' .
Column I Column II
A. Hypothalamic hormone I. Skin
B. Thyrotropin (TSH) II. Adrenal cortex ·.'
C. Corticotrophin Ill. Thyroid
D. Gonadotrophins (LH, FSH) IV. Gonad
E. Melanotrophin (MSH) V. Pituitary
(a) A- I, B - II , C - Ill, D - IV, .E - V (b) A- V, B - IV, C - Ill, D - II, A- I
(c) A- V, B - Ill, C - II, D - IV, E - I (d) A- V, B - II, C - Ill, D - IV, E - I
31 . Cretinism in children is caused by-
(a) Hypothyroidism (b) Hyperthyroidism (c) Hypoparathyroidism (d) Hyperparathyroidism
. ..
32. The features of cretinism includes -
(a) mental retardation, low l.Q. (b)Abnormal skin, stunted growth
• (c) Deaf-mutism (d)All
33. Which of the following statements is correct?
(a) In an adult woman, hypothyroidism may cause irregular menstrual cycle.
(b) Hyperthyroidism may be resulted due to thyroid cancer or nodules development in the thyroid glands
(c) Deficiency of iodine in our diet results in hypothyroidism
(d)All
34. I. Maximum iodine is stored in thyroid gland
II. Calcitonin is non-iodinised hormone secreted by parafollicular cells of thyroid giand.
Ill. Calcitonin (TCT) regulates the blood Ca +2 level. .
IV. TCT is hypocalcemic factor
(a) All are correct (b)All are wrong
(c) Only I, II and Ill are correct (d) Only IV is correct
35. Which one of the following pairs of organs includes only the endocrine glands?
(a) Thymus and testes (b)Adrenal and ovary
(c) Parathyroid and adrenal (d) Pancreas and parathyroid
36. In humans, _ _ _ _ _ parathyroid glands are present on _ _ _ _ _ side of _ _ _ _ gland -

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I Chemical Coordination and Integration
(a) 2, back, thyroid gland_s (b) 4, back, thyroid glands
(c) 4, front, thyroid glands (d) 2, lateral, thyroid glands
37. Which of the following is I are influenced by parathyroid hormone (PTH) or Collip's hormone?
(a) Only kidney (b) Kidney & bones only
(c) Muscles and bones only (d) Kidney, bone, muscles and small intestine
38. All are the functions of PTH except -
(a) PTH stimulates bone reabsorption I dilutio'n I demineralization
(b) PTH retards osteoclastic action
(c) PTH increases Ca+ 2 absorption from the digestive tube
(d) PTH stimulates reabsorption of ca+2 by the renal tubules
39. PTH is a-
(a) Hypocalcemic hormone (b) Hypercalcemic hormone
(c) Antiosteoclastic hormone (d) A hormone which stimulates excretion of ca•2 in urine
40. The thymus gland is a lobular structure located on _ _ _ _ side of the and _ _ _ __
(a) Ventral , heart, aorta (b) Lateral, heart, aorta (c) Dorsal , heart, aorta (d) Dorsal, thyroid , trachea
41 . Which of the following endocrine glands degenerates I atrophies in old age?
(a) Thyroid (b) Thymus (c) Parathyroid (d)Adrenal
42. Thymus is mainly concerned with -
(a) Regulation of body temperature (b) Regulation of body growth
(c) Immunological functions (d) Secretion of thyrotropin
43. Damage to thymus in a child may lead to -
(a) A reduction in haemoglobin content of blood
(b) Loss of cell mediated immunity
(c) Promotion of antibody mediated immunity I humeral immunity
(d) A reduction in stem cell production
44. The thymus gland secretes the _ _ _ _ _ hormone called _ _ _ _ _ _ which play a major role in the differen-
tiation of lymphocytes.
(a) Glycoproteinaceous, thymosin , T (b) Steroid, thymosin , T
(c) Peptide, thymosin, T (d) Peptide, thymosin, B
45. Which of the following is not related with thymosins?
(a) In addition to cell mediated immunity, thymosins also promote production of antibodies to provide humeral immunity
(b) In old age, thymosins production is more, so immunity is strong
(c) Thymosins are produced by thyroid gland
(d) Both band c A
'
c'
46. Observe the following diagrams and identify alphabetized items -
(a) A-Adrenal gland,B- Fat, C-Cortex, D- Medulla
(b) A - JGA, B - Fat, C - Cortex, D - Medulla
(c)A-Adrenal gland , B - Fat, C-Medulla, D - Cortex
(d) A - Adrenal gland , B - Fat, C - Pars distalis, D - pars intermedia

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 Chemical Coordination and Integration
47. Adrenal medulla secretes-
(a) Adrenaline I epinephrine only (b) Nor-adrenaline I nor-epinephrine
(c)aandb (d) Corticoids
48. Ad.renaline and nor-adrenaline are commonly called - ·
(a) Corticoids .(b) Glucocorticoids (c) Catecholamines (d) Sex corticoids
49. Which of the following glands is called emergency gland of the body?
(a) Testis (b) Adrenal medulla (c) Thyroid (d) Pituitary
50. Which of the following hormone(s) is/ are called emergency hormone(s) of "fight or flight"?
(a)ADH (b) Oxytocin
(c)Adrenaline and nor-adrenaline (d) Thymosis and PTH
51 . Which of the following hormones increase alertness, pupillary dilation , piloerection , sweating, heart beat, strength of
heart contraction, rate of respiration , glycogenolysis, lipolysis, proteolysis and glucose cone. in blood?
(a) thymosin and calcitonin (b) Norepinephrine and epinephrine
(c) Vasopressin and oxytocin (d) Insulin and glucagon
52. The fight-or-flight response is developed by the hormones of-
(a) Hypothalamus (b)Adrenal medulla (c)Adrenal cortex (d)Adrenal-pancreatic complex
53. B.P. is controlled by -
(a) Adrenal gland (b) Thymus (c) Corpus luteum
(d) None
54. Adrenal cortex is composed of 3 layers. The sequence of layers from the outside to the inside is -
(a) Zona glomerulosa, zona fasciculata , zona reticularis
I •
(b) Zona reticularis, zona glomerulosa , zona fasciculata
(c) Zona fasciculata, zona reticularis , zona glomerulosa
(d) Zona fasciculata , zona glomerulosa , zona reticularis
55. The adrenal cortex secretes many hormones, commonly called as -
(a) Epinephrine (b) Corticoids (c) Non-epinephrine (d) Secondary messengers
56. Match the Column I with Column II -
Column I Column II
A Glucocorticoids I. Balance of water and electrolytes in our body
B. Mineralocorticoids 11. Carbohydrate metabolism
C. Gonadocorticoids Ill. Secretion of estrogens and androgens
(a)A-ll , B-l,C-111 (b)A-1 , B-ll , C-111 (c)A-111 , B-ll , C-I (d) A- Ill, B - I, C - II
57. Which of the following is the main glucocorticoid?
(a)Aldosterone (b) Gonadocorticoid (c) Cortisol (d) Mineralocorticoids
58. Which of the following hormones is the main mineralocorticoid?
\a) ~t:l<:J~\~~<:J°t'I~ \'\J) ~<:J~\~<:J\ \c) ~\J'n
59. Match the source gland with its respective hormone and function and select the correct option .
Source gland Hormone Function
(a) Anterior pituitary Oxytocin Contraction of uterus muscles during child birth
(b) Posterior pituitary Vasopressin stimulates reabsorption of water in the distal tubules in the nephron
(c) Corous luteum Oestroaen Suooorts Pregnancy
(d) Thvroid Thvroxine Reaulates blood calcium level
60. Which one of the following does not act as a neurotransm_itter?
(a) Cortisone (b) Epinephrine (c) Norepinephrine (d) Acetylcholine
61 . Gluconeogenesis, lipolysis, proteolysis and inhibitiori of cellular uptake and utilization of amino acid are performed by -
(a) Aldosterone (b) Glucocorticoid (c) Insulin (d) Mineralocorticoid

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I Chemical Coordination and Integration https://neetmedicalacademy.blogspot.com

62 . Which of the following hormones produces anti-inflammatory reactions, suppresses immune response, stimulates
RBC production, and is also involved in maintaining cardiovascular system and kidney functions?
(a)Aldosterone (b) Epinephrine (c) Cortisol (d) Norepinephrine
63. Which of the following adrenal cortical hormones play a role in the growth of axial hair, pubic hair and facial hair during
puberty?
(a) Cortisol (b)Androgens (c) Norepinephrine (d) Epinephrine
64 . Which of following statements is false about pancreas?
(a) Pancreas acts as both exocrine and endocrine glands
(b) Endocrine pancreas consists of "Islets of Langerhans"
(c) There are about 1-2 million Islets of Langerhans representing only 1-2% of pancreatic tissue
(d) Pancreas secretes only insulin

65. l!?let of Langerhans

I
has 2 types
of main cells ,...,

t A-

B-

Identify A to E -
cells~ secretes insulin ~causes - D
cells~ secretes - C ~causes -E
'·

(a) A- a , B - 0. C - Glucagon, D - Hyperglycemia, E - Hypoglycemia .

(b) A- 0. B - a , C - Cortisol, D - Hypoglycemia, E - Hyperglycemia

(c) A- 0. B - a , C - Cortisol, D - Hyperglycemia, E - Hypoglycemia -.

(d) A- 0. B - a, C - Glucagon, D - Hypoglycemia, E - Hyperglycemia
66. Which of the following best describe the functions of corticosteroid hormones?
..
I. Depresses the immune response
II . Stimulates sexual and reproductive activity
.
'~

Ill. Influences blood glucose concentration

IV. Influences ionic and osmotic concentration of blood
(a) All (b) I, II, Ill (c) IV (d) None
67. Cortisol, the stress hormone, has all the following effects except-
(a) metabolizing fat for energy (b) Increasing B.P.
(c) Stimulating the immune response (d) Slowing down the protein synthesis
68. Which of the following statements is correct about glucagon?
(a) Glucagon acts mainly on the liver cells (hepatocytes)
(b) Glucagon stimulates glycogenolysis, gluconeogenesis
(c) Glucagon reduces the cellular glucose uptake and utilization
(d)All
69. Insulin , a peptide hormone like glucagon, has all the following effects except-
(a) Insulin acts mainly on hepatocytes and adipocytes and enhances cellular glucose uptake and utilization
(b) Insulin causes a rapid movement of glucose from blood to hepatocytes and adipocytes
(c) Insulin is hypoglycemic factor
(d) Insulin reduces glycogenesis
70. The glucose homeostasis in blood is maintained jointly by -
(a) Insulin and epinephrine(b) Insulin and nor-epinephrine
(c) Insulin and glucagon (d) Glucagon and cortisol

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 Cltemical Coordi11atio11 and Integration
71 . Prolonged hyperglycemia leads to a complex disorder called -
(a) Diabetes metlitus (b) Diabetes insipidus (c) Cretinism (d) Myxoedema
72. A pair of testis is present in the sac (outside abdomen) of male individual. Testis consists of _ _ __
tubules and or interstitial tissue
(a) Testicular, seminiferous, stromal (b) Scrotal , seminiferous, stromal
(c) Scrotal, uriniferous, stromal (d) Scrotal, seminiferous, seminal
73. Go through the following points -
I. Regulate the development, maturation and functions of epididymis, vas deferens, seminal vesicle, prostrate gland
urethra, etc.
II. Stimulate muscular growth of facial and axillary hairs, aggressiveness, low pitch of voice, etc.
Ill. Stimulates spermatogenesis
IV. Act on CNS and sexual behaviour (libido)
V. Produce anabolic (synthetic) effect on protein and carbohydrate metabolism
VI.The Leydig's cell/ interstitial cells (present in intertubular space) secrete tf:lis hormone under the. influence .of LH
Above points are associated with _ _ _ _ hormones -
·(a) FSH (b) Progesterone
(c) Androgens (e.g. Testosterone) (d) Melatonin
74. Which of the following statements is incorrect?
(a) Testis and ovary function as a primary sex organ as well as endocrine gland
(b) Ovaries are located in thoracic cavity of females
(c) Ovary produces ovum, 2 groups of steroid hormones (estrogen and progesterone)
(d) Ovary is composed of ovarian follicles and stromal tissue
75. Find the odd one out with respect to site of hormones production -
(a) Epinephrine, Nor-epinephrine, Cortisol (b) FSH , TSH , GH
(c) Progesterone, Testosterone, Relaxin (d) Insulin, Glucagon, Thymosin
7.6. Find the odd one out -
(a) Insulin, Glucagon, Thymosin (b) Glucocorticoids, Mineralocorticoids, sex corticoids
(c) Relaxin, Oestrogen, progesterone (d) Nor-epinephrine, Adrenaline
77. The corpus luteum is the structure which -
(a) Releases ovum from ovary (b) Secretes progesterone
(c) Develops in Graafian follicle (d) Produces LH
78. After ovulation, the ruptured follicle is converted into-
(a) Graafian follicle (b) Corpus callosum (c) Corpus luteum (d) Corpus spongiosum
79. The estrogen is mainly synthesised and secreted by -
(a) Rupture follicles in ovary · (b) Corpus luteum
(c) Growing ovarian follicles (d) Leydig cells
80. Progesterone-
(a) Supports pregnancy (b) Stimulates the formation of mammary alveoli
(c) Stimulates milk secretion (Lactation) (d)All
81. Which of the following hormones stimulates growth and development of female accessory sex organs and secondal)
sex character and also female sexual behaviour?
(a) Estrogen (b) Progesteron
.
.•• (c)Androgen (Testosterone) (d) Gonadotrophic releasing hormone
82. · Which of the following secretes hormones but is not considered as traditional glandular tissue?
(a) Pancreas (b) Testes (c) Heart (d) Adrenal gland
83. Production , secretion and ejection of milk requires the synergistic effects of prolactin and -

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 Chemical Coordi11atio11 and J11tegrntio11

(a) Estrogen { b) Progesteron (c) Oxytocin (d)All

84. A hormone not involved in sugar metabolism is -
(a) Glucagon (b) Cortisone (c)Aldosterone (d) Insulin
85. Atrial natriuretic hormone I factor (ANF) secreted by atrial wall of our heart has exactly the opposite function of this
hormone secreted by zona glomerulosa -
(a)ADH (b} Aldosterone (c)Androgen (c:j) Calcitonin
86. ANF-
(a) Decrease B.P. (b) Is secreted when B.P. increases
(c) Causes vasodilation (d)All
87. Juxtaglomerular cells of produces a peptide hormone called which stimulates _ _ __
(a) Thyroid , erythopoietin, erythropoiesis (b) Kidney, erythropoietin, erythropoiesis
(c) Kidney, renin , erythropoiesis (d} Spleen, erythropoietin , erythropoiesis
88. Which one of the following part acts as an endocrine gland or tissue?
(a) Pars radiata (b) JG cells (c) Brunner's gland (d) Pancreatic acini
89. Gastrin, secretin, cholecystokinin (CCK) and gastric inhibitory peptide (GIP) are 4 major peptide hormone secreted by-
(a) Only stomach (b} Only small intestine (c) Gastro-intestinal tract (d) Only pancreas
90. Match Column I with Column II -
Column I Column II
A. Gastrin I. Acts on gastric gland and stimulates secretion of HCI and pepsinogen
B. Secretin II. Acts on the exocrine part of pancreas and stimulates secretion of W!lter and HC0 3- ions
C.CCK Ill. Acts on both pancreas and gall bladder and stimulates the secretion of both pancreatic
enzymes and bile juice respectively -
0 . GIP IV. Inhibits gastric secretion and motility
(a) A- IV, B - Ill , C - 11 , D - I (b) A- II , B IV, C - Ill , D - I
(c} A-1 , B - II, C - Ill , D - IV (d) A-1 , B - Ill , C - II , D - IV
91 . Which of the following statements is false?
(a) Growth factors I Hormones are also secreted by specific non-endocrine tissues
(b) These growth factors are essential for normal growth of tissues and their repairing I regeneration
(c) Hormone secreted during allergy is glucocorticoid
(d) None of the above
92. Match the Column I with Column II -
Column I Column II
A. Peptide, polypeptide protein hormones I. Epinephrine, nor-epinephrine
B. Steroid II. T 3 and T 4 (thyroid hormones)
C. lodothyronines Ill. Cortisol, testosterone , estradiol, progesterone
D. Amino acid derivatives IV. Pituitary hormones, pancreatic hormones, hypothalamic hormones
(a) A-1 , B - II , C - Ill , D - IV (b) A- IV, B - Ill , C - II , D - I
(c) A- IV, B - 111 , C - I, D - II (d) A- I, B - II, C - IV, D - Ill
93. A steroid hormone typically alters the activity of its target cells by -
(a) Making holes in the membrane of the target cells
(b) Entering the cell and altering gene expression
(c) Making holes in the lysosome of target cells
(d) Activation of cAMP
94. The target tissues of hormones are those tissues that -
(a) Particular hormone can actually penetrate
(b) Have specific enzymes with which hormones directly interact

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 Chemical Coordination and Integration

(c) Have hig h concentrations of the "second messenger" .

(d) Have rece ptors for particular hormone -
95. In order for a cell to be responsive to a lipid-soluble hormone, it must have -
(a) G - protein (b) cAMP
(c) A specific receptor in the cytoplasm or nucleus (d) A specific cell surface receptor
96 . Steroid hormones initiate the production of target cell substances in which manner?
(a) They initiate second messenger activity (b) They bind with membrane protein
(c) They initiate DNA transcription (d) They activate enzyme pathways
97. Which of the following is not true of cyclic AM P (cAMP)?
(a) It is a secon d messenger
(b) The enzyme adenylate cyclase converts ATP into cAMP
(c) In the mechanism of a protein hormone, cAMP is involved
(d) None
98. Why do some hormones (first messenger) n"eed to trigger a "second messenger" to activate a target cell?
(a) The first messeffger needs activation of ATP
(b) The first messenger cannot cross a pla sma membrane
(c) There are no specific cell surface receptors for first messenger
(d) The first messenger is not a water-soluble molecule
99. Which of the following is I are second messenger(s)? .
(a) cAMP (b) IP 3 (c) ca+2 (d)All
100. Which of the fo llowing hormones does not act by a second messenger system?
(a) Glucagon ~b) Epinephrine (c) FSH (d) Testosterone
101 . Which hormone binds to intracellular receptors -
(a) Insulin (b) GH (c) T 3 (d) TSH
102. Which of the fo llowing hormones does not act by a second messenger system?
(a) Glucagon (b) Epinephrine (c) LH (d)Aldosterone
103. Place in the correct order the action of water soluble hormones e.g. FSH
I. Physiological response e.g . ovarian growth
II. Biochemical response
Ill. Generation of second messenger
IV. Response I
V. Hormone binds to plasma membrane bind
(a) I~ II~ Ill ~ IV~ V (b)V~ IV~ Ill~ II~ I
(c) V ~IV ~ II~ Ill ~I (d) I~ II~ V ~Ill~ IV
104. Hormones produce their effect on target tissue by binding to specific A called hormone receptors located in the
target tissues only. B soluble hormones usually need C receptor that generate D messen-
gers for regu lating cellular metabolism. E soluble hormones can pass through cell membrane and bind to
F receptors, mostly G receptors. The hormone receptor complex enter the H and mostly
regulate gene expression or chromosome fu nction by interaction of hormone-receptor complex with the I
(a) A- Protein, B - Water, C - Membrane-bound, D - Second , E - Lipid , F - intracellular, G - Nuclear, H - Nucleus,
I - Genome
(b) A- Lipid , B - Water, C - Membrane-bound , D - Second , E - Water, F - intracellular, G - Nuclear, H - Nucleus,
I -Genome
(c)A- Protein, B - Water, C- Intracellular, D-Second, E- Lipid, F - Extracellular, G - Nuclear, H - Nucleus, I -Genome
(d) A- Protein, B - Water, C - Membrane-bound , D - Primary, E - Lipid , F - intracellular, G - Nuclear, H - Nucleus,
I-Genome

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 Chemical Coordination and Integration

105.
D
cS E

Response 1 cell
~ membrane
Generation of C "'r--•H
.jJ
Biochemical Responses i
"J I Figure -11
{!-
Physiological Respanses i
Physiological responses
Figure -1
Go through the above diagrammatic representation of the mechanism of action for 2 categories of hormones. In which
of the following options correct answers for blanks A to I are indicated .
(a) A-Steroid hormone, B- Receptor, C-Secondary messenger, D - Non-steroid hormone, E - Nucleus, F - Hormone-
receptor complex, G - Genome, H - mRNA, I - protein
(b)A- Non-steroid hormone, B - Receptor, C-Secondary messenger, D-Steroid hormone, E- Nucleus, F - Hormone
receptor complex , G - Genome, H - mRNA, I - Protein
(c) A- Steroid hormone, B - Receptor, C - Primary messenger, D - Non-steroid hormone, E - Nucleus, F - Hormone-
receptor complex, G - Genome, H - mRNA, I - protein
(d)A-Steroid hormone, B- Enzyme, C-Secondary messenger, D- Non-steroid hormone, E - Nucleus, F - Hormone-
enzyme complex, G - Genome, H - mRNA, I - protein
106. Match each hormone (Column - I) with its effect on target cells (Column - II) and the gland where it is prod uced
(Column - Ill)-
Column -1 Column -11 Column -111
1. Thyroxine A Lowers P. Pineal gland
2. Insulin B. Blood glucose stimulates ovary Q . Testes
3. PTH C . Triggers "fight or flight" R. Parathyroid Gland
4. Epinephrine D. Promotes male traits S. Adrenal medulla
5. Melatonin E. Regulate metabolism T. Hypothalamus
6. ADH F. Related to daily rhythm U. Pancreas
7. Androgen G. Rises blood Ca•2 1evel V. Anterior pituitary
8. FSH H. Boost water retention W. Thyroid gland
(a) 1 - E, W; 2 -A, U; 3 - G, R; 4 - C, S; 5 - F, P; 6 - H, T; 7 - D, Q; 8 - B, V
(b) 1 - E, W ; 2 -A, R; 3 - V, R; 4 - C, U; 5 - F, T; 6 - H, S; 7 - D, Q; 8 - B, P
(c) 1 - B, V; 2 - E, U; 3 - G, W ; 4 - C, S; 5 -A, P; 6 - H, T; 7 - D, Q; 8 - F, R
(d) 1 -A, W; 2 - C , U; 3 - G, R; 4 - E, S; 5 - F, P; 6 - H, T; 7 - D, Q ; 8 - B, V
107. The numbered structures in the diagram represent two human endocrine glands.

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 Chemical Coordination and Integration

Which line in the table gives the correct sites of production of the three hormones?
Thyroxine Somatotrophin Thyroid-stimulating hormone
(a) 2 1 2
(b) 2 1 1
(c) 1 2 1
(d) 1 2 2
108. Hormones are regulatory molecules secreted by the endocrine systems in vertebrates. Which of the following state-
ments is NOT TRUE for hormones?
(a) Hormones are secreted into the blood circulation system and they act on target organs.
(b) Amino acids are precursors for some hormones.
(c) Hormones can act on the organ that secretes them.
(d) Hormones are always short-lived molecules.
109. Choose the the false one.
(a) Thymus is degenerated in old aged persons resulting in a decreased thymosins production leadi~g to wea,k
immune response.
(b) Cortisol, a type of glucocorticoids stimulates the RBC production
(c) Small amount of androgenic steroids is secreted by adrenal cortex.
(d) Diabetes is not successfully treated with insulin
110. Along with which hormone parathyroid hormone plays a significant role in Ca-balance in the body?

111 .
(a)T3 (b)T4 (c)TCT
-(d)IAA
"Y" is hormone which acts mainly at the renal tubules and stimulates the absorption of Na+ and water and excretion
of K+ and phosphate ions. Thus it helps in the maintenance of electrolytes body fluid volume, 0-P and B.P. Y is
(a)Aldosterone I mineralocorticoids (b) GH
(c) GIP (d)ANF
112. Given below is an incomplete table about certain hormones, their source glands and one major effect of each on the
body in humans . Identify the correct option for the three blanks A, B and C.
GLANDS SECRETION EFFECT ON BODY

6 Oestrogen Maintenance of secondary sexual characters

Alpha cells of Islets of Langerhans .!2 Raises blood sugar level

Anterior pituitary Q. Over secretion leads to gigantism

Options
A B c
(a) Placenta Glucagon Calcitonin
(b) Ovary Glucagon Growth hormone
(c) Placenta Insulin Vasopressin
(d) Ovary Insulin Calcitonin
113. Which of the following is the more scientific definition of hormone ?
(a) They are extracellular messengers
(b) They always act at distantly located target organ
(c) They are the products of well organized endocrine glands
(d) They are non-nutrient chemicals that act as intercellular messengers
114. Mark the correct statement regarding somatostatin
(a) It is secreted from anterior pituitary (b) It inhibits the release of growth hormone

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 Chemical Coordination and Integration

(c) It is secreted from posterior pituitary (d) It stimulates STH secretion

115. Gonadotrophins are secreted from
(a) Hypothalamus (b) Neurohypophysis (c) Pars distalis of Pituitary (d) None of these
116. Sleep-wake cycle and menstrual cycle are maintained by
(a) Progesterone (b) Melatonin (c) Oxytocin (d) MSH
117. What is true about calcitonin
(a) It is released from thyroid gland (b) It contains iodine
(c) It is released from parathyroid (d) It is an amino acid
118. Alertness, pupillary dilation and piloerection are due to the effect of
(a) Melatonin (b) Corticoids (c) Catecholamines (d) Thyroxine
119. Vasopressin , also called ADH , is synthesized by
(a) Adenohypophysis (b) Hypothalamus (c) Neurohypophysis (d) Kidney
120. Which statement, regarding PTH , is correct?
(a) it is a peptide hormone (b) It stimulates bone resorption
, (c) it is hypercalcemic hormone (d)All of these
1'2"1 : Which of the following is not the hormone of anterior pituitary?
(a) Prolactin (b) Oxytocin (c)ACTH (d) Growth hormone
122. Cell mediated as well as humeral immunity is provided by
(a) PTH (b) Glucocorticoid (c) Thymosin (d) Thiamine
123. Which hormone interacts with membrane bound receptor and does not normally enter the target cell
(a) FSH (b) Estrogen (c) Thyroxin (d) Cortisol
124. Which of the following is the function of testosterone
. (a) It stimulates muscular growth and aggressiveness
(b) It influences male sexual behaviour (libido)
(c) It causes anabolic (synthetic) effect on protein/carbohydrate metabolism
(d)All of these
125. Which hormone acts on exocrine part of pancreas?
(a) GIP (b) Insulin (c) Secretin (d) Steapsin
126. The hormone that supports pregnancy and stimulates mammary glands for the formation of alveoli for storing
milk, is secreted from
(a) Ant. Pituitary (b) Post. Pituitary (c) Graafian follicle (d) Corpus luteum
127. The hormone that suppresses the immune system is
(a) Glucagon (b) Thymosin (c)Adrenaline (d) Cortisol
128. Juvenile diabetes mellitus is due to _ _ __
(a) loss of pancreatic beta cells (b) resistance to insulin
(c) obesity (d) malnutrition
129. Which one among the following hormones has no sexual importance?
(a) Interstitial cell stimulating hormone (b) Prolactin
(c) Human chorionic gonadotropin (d) Antidiuretic hormone
130. Which of the following hormones stimulate production of estrogen at puberty?
(a) FSH and LH (b)ACTH (c) TSH (d) GH
131. Which one among the following hormones is not secreted by adenohypophysis?
(a) FSH (b) ICSH (c) LH (d) hCG
132. The 24 hour (diurnal) rhythm of our body such as the sleep-wake cycle is regulated by the hormone :
(a) calcitonin (b) prolactin (c) adrenaline (d) melatonin
133. The given table enlists various hormones and their chemical nature.
No. Hormone Chemical composition
1. i Peptide
2. Testosterone ii
3. Thyroxine iii
4. iv Amino-acid derivative

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 Chemical Coordination and Integration

The information in which alternative completes the given table?

(a) i-Cortisol; ii-Steroids; iii-Polypeptide; iv-Estradiol
(b) i-lnsulin; ii-Proteins; iii-Polypeptide; iv-Epinephrine
(c) i-Cortisol; ii-Proteins; iii-lodothyronines; iv-Estradiol
(d) i-lnsulin ; ii-Steroids; iii-lodothyronines; iv-Epinephrine
134. The given table enlists various hormones produced in human body along with source gland.
No. Hormone Source gland
1. Melatonin
2. ii Thymus
3. iii Kidneys
The information in which alternative completes the given table?
(a) i-Pineal gland ; ii-Thymosin ; ii-Erythropoietin (b) i-Parathyroid gland; ii-Thymosin; iii-Erythropoietin
(c) i-Parathyroid gland ; ii-Epinephrine; iii-Secretin (d) i-Pineal gland ; ii-Epinephrine; iii-Secretin ·
135. The region of ii , which is also known as anterior pituitary produces iii and luteinizing hormones
(a) i-pars distalis; ii-adenohypophysis; iii-oxytocin ' '
(b) i-pars distalis; ii-adenohypophysis; iii-prolactin
(c) i-pars intermedia; ii-neurohypophysis; iii-oxytocin
(d) i-pars intermedia; ii-neurohypophysis; iii-prolactin
136. The melanocyte stimulating hormone is produced by_-=---· which is a part of_...;.;'-;_region of the pituitary gland
(a) i-pars intermedia; ii-adenohypophysis (b) i-pars intermedia; ii-neurohypophysis
(c) i-pars nervosa; ii-adenohypophysis (d) i-pars nervosa; ii-neurohypophysis
137. The hormones labelled , I, II, Ill, and IV, are secreted by the respective organs listed in the table
Hormone Organ
I. Ovarian follicle
II. Corpus luteum
Ill. Adrenal medulla
IV. Adrenal cortex
The information in which alternative correctly matches the secretions (hormones) by the respective organs?
(a) I-Progesterone; II-Epinephrine; 111-Corticoids; IV-Estrogen
(b) I-Progesterone; II-Estrogen; 111-Corticoids; IV-Epinephrine
(c) I-Estrogen; II-Progesterone; Ill-Epinephrine; IV-Corticoids
(d) I-Estrogen; 11-Corticoids; Ill-Epinephrine ; IV-Progesterone
138. Which of the following tables represents the pancreatic cells and their secretions correctly?
(a) Cell a-Glucagon ; Cell~ - Insulin (b) Cell a - Insulin; Cell~ -Glucagon
(c) Cell a- Glucagon ; Cell~ -Glucagon (d) Cell a - Insulin; Cell~ - Insulin
139. Match diseases with hormone deficiency.
Diseases Hormone deficiency
I. Dwarfism A. Thyroxine
11 . Acromegaly 8. GH
Ill. Simple goitre C. Aldosterone and cortisol
IV. Exophthalmic goitre D. Corticosteroid
V. Addison's disease E. Mineralocorticoids (Aldosterone)
VI. Conn's disease
VII. Cushing disease
(a) 1-8; 11-8; Ill-A; IV-A; V-C ; Vl-E; Vll-D (b) 1-8; II-A; Ill-A; IV-8; V-E; Vl-D; Vll-C
(c) I-A; 11-8; 111-8; IV-A; V-C ; Vl-E ; Vll-D (d) I-A; II-A; 111-8; IV-8; V-C ; Vl-D; Vll-E

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 Cltemica/ Coordination and Integration

140. A person entering an empty room suddenly finds a snake right in front on opening the door. Which one of the following
is likely to happen in his neuro-hormonal control system ?
(a) Sympathetic nervous system is activated releasing epineph rine and norepinephrine from adrenal medulla.
(b) Neurotransmitters diffuse rapidly across the cleft and tra nsmit a nerve impulse.
(c) Hypothalamus activates the parasympathetic division of brain.
(d) Sympathetic nervous system is activated releasing epinephrine and norepinephrine from adren al cortex.
141. The Leydig cells found in the human body are the secretory source of
(a) Progesterone (b) intestinal mucus (c) glucagon (d) androgens
142. Which one of the following pairs of hormones are the example s of those that can easily pa ss th rough the cell
membrane of the target cell and bind to a receptor inside it (Mostly in the nucleus)
(a) Insulin, glucagon (b) Thyroxin , insulin
(c) Somatostain , oxytocin (d) Cortisol , testosterone
143. What is correct to say about the hormone action in humans
• c (a) Gh,1cagon is secreted by ~ -cells of Islets of Langerhans and stim ulates glycogenolysis
(b) Secretion of thymosins is stimulated with aging
(c) In females FSH first binds with specific receptors on ovarian cell membrane
(d) FSH stimulates the secretion of estrogen and progesterone
144. A pregnant female delivers a baby who suffers from stunted growth, mental retardation/low intelligence quotient and
abnormal skin. This is the result of:
(a) Low secretion of growth hormone (b) Cancer of the thyroid gland
(c) Over secretion of pars distalis (d) Deficiency of iodine in diet
145. Which of the following statement is correct in relation to the endocri ne system?
(a) Organs in the body like gastrointestinal tract, heart, kidney and liver do not produce any hormones.
(b) Non - nutrient chemicals produced by the body in trace amount that act as intercellular messenger are known as
hormones.
(c) Releasing and inhibitory hormones are produced by the pituitary gland .
(d) Adenohypophysis is under direct neural regulation of the hypothalamus.
146. Select the answer which correctly matches the endocrine gland with the hormone it secretes and its function/ defi-
ciency symptom ·
Endocrine gland Hormone .Function/ deficiency symptoms _
(1) Posterior pituitary Growth Hormone (GH) Over secretion stimulates abnormal growth
(2) Thyroid gland Thyroxine Lack of iodine in diet results in goitre
(3) Corpus luteum Testosterone Stimulates spermatogenesis
(4) Anterior pituitary Oxytocin Stimulates uterus contraction duri ng child birth
(a) Option (1) (b) Option (2) (c) Option (3) (d) Option (4)
147. Figure shows human urinary system with structures labelled A to D. Select option which co rrectly id!=!ntifies them and
gives their characteristics and I or functions .

Kidney

Urinary bladder

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 Cliemicat Coordination and Integration

(a) B - Pelvis - broad funnel shaped space inner to hilum, directly connected to loops of Henle.
(b) C - Medulla - inner zone of kidney and contains complex nephrons.
(c) D- Cortex - outer part of kidney and do not contain any part of nephrons
(d) A-Adrenal gland - located at the anterior part of kidney. Secrete Catecholamines which stimulate glycogen breakdo •
148. Thyroxin act on every organ except -
(a) Brain (b) Testes (c) Thyroid (d) All of the these
149. When the normal heart of a frog is injected with physiological concentration of adrenaline, it shows -
(a) Systolic arrest (b) Sustained increase rate
(c) Decreased rate (d) First increase then normal rate
150. Injury localized to the hypothalamus would most likely disrupt:
(a) short - term memory. (b) co-ordination during locomotion.
(c) executive functions , such as decision making. (d) regulation of body temperature.
151. Identify the hormone with its correct matching of source and function :
(a) Oxytocin - posterior pituitary, growth and maintenance of mammary glands.
(b) Melatonin - pineal gland, regulates the normal rhythm ofsleepwake cycle.
(c) Progesterone - corpus-luteum , stimulation of growth and activities of female secondary sex organs. , '
(d) Atrial natriuretic factor - ventricular wall increases the blood pressure.
152. Fight-or-flight reactions cause activation of :
(a) the parathyroid glands , leading to increased metabolic rate.
(b) the kidney, leading to suppression of reninangiotensin-aldosterone pathway.
(c) the adrenal medulla , leading to increased secretion of epinephrine and norepinephrine.
(d) the pancreas leading to a reduction in the blood sugar levels.
153. Which one of the following hormones also produces anti-inflammatory reactions in man and suppresses the immi.. - =
response in addition to its primary functions?
(a) Thyrocalcitonin (b) Cortisol (c) Erythropoietin (d) Thymosin
154. Which of the following represents the action of insulin?
(a) Increases blood glucose levels by hydrolysis of glycogen
(b) Increases blood glucose levels by stimulating glucagon production
(c) Decreases blood glucose levels of forming glycogen
(d) Increases blood glucose level by promoting cellular uptake of glucose
155. Norepinephrine:
I. Is released by sympathetic fibres
II. Is released by parasympathetic fibres
Ill. Increases the heart rate
IV. Decreases blood pressure
Which of the above said statements are correct?
(a) I and IV (b) I and Ill (c) II and Ill (d) II and IV
156. Select the option which correctly matches the endocrine gland with its hormone and its function
Endocrinegland Hormone Function
(a) Ovary FSH stimulates follicular development and the secretion of estrogens.
(b) Placenta estrogen initiates secretion of the milk.
(c) Corpus luteum estrogen essential for maintenance of endometerium.
(d) Leydig cells androgen initiates the production of sperms.
157. Which of the following pituitary hormones is secreted without the involvement of a releasing hormone (RH)?
(a) Thyroid Stimulating Hormone (TSH) (b) Fotlicle Stimulating Hormone (FSH)
(c) Oxytocin (d) Prolactin
158. Which of the following hormones is a derivative of fatty acid?
(a) Gastrin (b) Thyroxin (c) Estrogen (d) Prostaglandins

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 Chemical Coordination "nd l11tegratio11

159. Find the incorrect match w.r.t. structure I cell and its hormone concerned .
(a) ~-cells of pancreas- Insulin
(b) Zona fasciculata of adrenal cortex-Cortisol
(c) Follicular cells of thyroid gland - Thyrocalcitonin
(d) Juxta-glomerular cells of kidney- Erythropoietin
160. Which of the following hormone is not produced by hypothalamus?
(a) Oxytocin (b) GnRH (c) Somatostatin (d) Somatotrophic hormone
161. A chemical signal that has both endocrine and neural roles is
(a) Epinephrine (b) Cortisol (c) Melatonin (d) Calcitonin
162. Which one of the following hormones is not invovled in sugar metabolism?
(a) Insulin (b) Glucagon (c) Cortisone (d) Aldosterone
163. Which one of the following hormones though synthesised elsewhere, is stored and released by the master gland?
(a) Prolactin (b) Melanocyte stimulating hormone
(c)Antidiuretic hormone (d) Luteinising hormone
164. The amino acid Tryptophan is the precursor for the synthesis of :-
(a) Melatonin and Serotonin (b) Thyroxine and Triiodothyronine
(c) Estrogen and Progesterone (d) Cortisol and Cortisone
165. The posterior pituitary gland is not a 'true' endocrine gland because:-
(a) It is under the regulation of hypothalamus (b) It secretes enzymes
(c) It is provided with a duct (d) It only stores and releases hormones
166. 'Grave's disease is caused due to :-
(a) Hyposecretion of adrenal gland (b) Hypersecretion of adrenal gland
(c) Hyposecretion of thyroid gland (d) Hypersecretion of thyroid gland
167. Name a peptide hormone which acts mainly on hepatocytes, adipocytes and enhances cellular glucose uptake and
utilization .
(a) Secretin (b) Gastrin (c) Insulin (d) Glucagon
168. The adrenal cortex synthesizes only :
(a) Steroid hormones (b) Peptide hormones (c) Glycopeptide hormones (d) Catecholamines
169. Oxytocin is synthesized in
(a)Adenohypophysis (b) Neurohypophysis (c) Hypothalamas (d) Epiphysis
170. Which of the following hormone is not chemically glycoprotein?
(a) Growth hormone (b) Prolactin (c) Luteinizing hormone (d) Estrogen
171 . Release of pancreatic juice is stimulated by :
I. Enterokinase II. Secretin Ill. Trypsinogen IV. Cholecystokinin
(a) All are correct (b)All are incorrect
(c) Both I and Ill are correct (d) Both II and IV are correct
Go throught the following statements.
I. Silicosis is the result of exposure to silica that causes permanent lung damage and death.
II . Transportation of gases and digested food materials in the body of higher animals causes muscle weakness and
fatigue
Ill. ADH is a neurohypophysial hormone that regulates body water
IV. Myasthenia gravis is a neuromuscular disease that is mediated by circulatory system
Which of the following statement(s) is/are correct?
(a) I and II are correct (b) II and Ill are correct (c) II and IV (d) I, Ill and IV are correct

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I Chemical Coordination and Integration
173. Which of the following hormones contains iodine?
(a) lnhibin (b) FSH (c) Prolactin (d) Thyroxine
174. Secretin is a gastrointestinal tract hormone that
(a) Acts on exocrine portion of pancreas and stimulates the secretion of water and bicarbonate ions.
(b) Acts on endocrine portion of pancreas and stimulates a-cells to secrete glucagon .
(c)Acts on gastric glands and stimulates secretion of hydrochloric acid and pepsinogen.
(d) Stimulates secretion of gastric lipase from stomach
175. Which of the following is considered as a hyperglycemic factor?
(a) Insulin (b) Glucagon (c)Aldosterone (d) Parathormone
176. ------hormone contracts gallbladder to release bile.
(a) Gastrin (b) Secretin (c) Enterogastrin (d) Cholecystokinin
177. The hormone which regulates the gene-expression of the target cell is
(a) Prolactin (b) Oxytocin (c) Thyroxin (d) Growth-hormone
178. A cell that contains proteins enabling a hormone to selectively bind to its plasma membrane is called a(n)
. (a) secretory cell. (b) plasma cell. (c) endocrine cell. (d) target cell.
179. Which of the following statements about hormones is incorrect?
(a) They are secreted into the extracellular fluid. (b) They circulate in blood or hemolymph .
(c) They communicate messages throughout the body.
(d) They travel through a dedicated pathway.
180. Which of the following statements about hormones is incorrect?
(a) Glands that produce them are ductless glands. (b) They are produced only by organs called endocrine orga _
(c) Some are water soluble and some are not. · (d) They often maintain steady-state conditions.
181 . Which of the following is the most likely explanation for hypothyroidism in a patient whose iodine level is normal"'
(a) a disproportionate production ofT 3 to T 4 (b) hyposecretion ofTSH
(c) hypersecretion ofTSH (d) hypersecretion of MSH
182. Excess secretion from this gland can cause a person to be thin, hyperactive, always hungry and irritable, with a h;-
metabolic rate.
(a) adrenal cortex (b) thyroid (c) pancreas (d) thymus
183. A decrease in blood pressure I volume will not cause the release of :
(a) Atrial natriu retie factor (b) Aldosterone (c) ADH (d) Renin
184. A temporary endocrine gland in the human body is :
(a) Corpus cardiacum (b) corpus luteum (c) Corpus allatum (d) Pineal gland
185. GnRH, a hypothalamic hormone, needed in reproduction, acts on :
(a) anterior pituitary gland and stimulates secretion of LH and FSH .
c· , '. ' (b) posterior pituitary gland and stimulates secretion of oxytocin and FSH .
(c) posterior pituitary gland and stimulates secretion of LH and relaxin .
(d) anterior pituitary gland and stimulates secretion of LH and oxytocin .
186. Hypersecretion of Growth Hormone in adults does not cause.further increase in height, because:
(a) Epiphyseal plates close after adolescence. (b) Bones loose their sensitivity to Growth Hormone in adul -
(c) Muscle fibres do not grow in size after birth . (d) Growth Hormone becomes inactive in adults.
187. Among various encountered in living cells the ions most commonly used as signals are -
(a) Fe++ (b) 1<+ (c) Na+ (d) ca++
188. Disorders caused by hypersecretion of concerned hormones are -
(a) gigantism and exophthalmic goiter (b) monogolism and cretinism
(c) cretinism, diabetes and goiter (d) rickets, diabetes mellitus

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 Cltemical Coordination and Integration

189.
Membrane
bound receptor Cell
®· -r-~ Nucleus
Intracellular--~
Receptor
Diagram showing the different receptors present on cell X and Y
Which group of hormone intract with 'Y'
(a) Thyroxine, estrogen (b) Thyroxine, FSH (c) FSH and Estrogen (d) FSH and LH
190. Read the following carefully.
I. Protein hormone interact with the intra cellular receptor
II. lodothyronine hormone generate secondary messenger after interaction with receptor
Ill. Hormone is a cell specific
IV. Somatostatin hormone secrete only by hypothalamus
How 1r,nany statements are not correct?
(a)1 (b)2 (c) 3 (d) 4
191. Which of the following is an amino acid derived hormone?
'' .
(a) Estradiol (b) Ecdysone (c) Epinephrine (d) Estriol
192. Which of the following hormones can play a significant role in osteoporosis?
(a) Estrogen and Parathyroid hormone (b) Progesterone and Aldosterone
(c)Aldosterone and Prolactin (d) Parathyroid hormone and Prolactin
193. Type-1 diabetes is -
(a) Insulin independent (b) Insulin dependent
(c) Caused by UV-radiation (d) Infectious
194. If the pH ofduodenum decreases below 5, then secretion of _ _ _ _ stop.
(a) Secretin (b) Enterokinase (c) CCK (d) Gastrin
195. Which of the following endocrine structure is not controlled by a tropic hormone from the anterior pituitary?
(a) Pancreatic islet cells (b) Thyroid gland (c)Adrenal cortex (d) Ovaries
196. A patient of diabetes mellitus excrets glucose in urine.even when he is kept in .a carbohydrate free diet. It is because
(a) fats are catabolised in adipose tissues to form glucose
(b) amino acids are catabolised in kidney to form glucose
(c) amino acids are discharged in blood stream from liver
(d) glycogen from muscles is released in blood stream
Which of the following statements is not correct ?
(a) In the knee-jerk reflex, stimulus is the stretching of muscle and response is its contraction
(b) An action potential in an axon does not mov~ backward because the segment behind is in a refractory phase
(c) Depolarisation of hair cells of cochlea results in the opening of the mechanically gated potassium-ion channels
(d) Rods are very sensitive and contribute to daylight vision
' 98. Artificial light, extended work-time and reduced sleep-time disrupt the activity of-
(a) Posterior pituitary gland (b) Thymus.gland (c) Pineal gland . (d) Adrenal gland
' 99. Which of the following conditions will stimulate parathyroid gland to release parathyroid_hormone?
(a) Rise in blood Ca+ 2 levels (b) Fall in active Vitamin D levels

(c) Fall in blood Ca+ 2 levels (d) Fall in bone Ca+ 2 levels
Which of the following hormones is responsible for both the milk ejection reflex and the foetal ejection reflex?
(a) Relaxin (b) Estrogen (c) Prolactin (d) Oxytocin

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 Cliemica/ Coordination anti Integration

201 . Match the following hormones with the respective disease

(A) Insulin (i) Addison's disease
(B) Thyroxin (ii) Diabetes insipidus
(C) Corticoids (iii)Acromegaly
(D) Growth Hormone (iv) Goitre
(v) Diabetes mellitus
Select the correct option .
(A) (B) (C) (D)
(a) (v) (i) (ii) (iii)
(b) (ii) (iv) (iii) (i) ' )

(c) (v) (iv) (i) (iii)

··~
(d) (ii) (iv) (i) (iii)
'.
202. Identify A, Band C in the diagrammatic representation of the mechanism of hormone action .
. '

' r

Response 1 C&ll
v memtirene
Generation ot C
.(;.
Biochemical Re&poosos
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Select the correct option from the following :

(a)A= Protein Hormone; B = CyclicAMP; C =Hormone-receptor Complex
(b)A= Steroid Hormone; B = Hormonereceptor Complex; C =Protein
(c)A= Protein Hormone; B =Receptor; C = CyclicAMP
(d)A= Steroid Hormone; B =Receptor; C =Second Messenger

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 Cllemict1/ Coordination anti Integmtion

II CHEMICAL COORDINATION AND INTEGRATION II

1. a 2. a 3. d 4. d 5. b 6. d 7. c 8. b 9. d 10. d
11. d 12. a 13. c 14. a 15. b 16. d 17. b 18. d 19. b 20. a
21. d 22. c 23. a 24. c 25. b 26. c 27. c 28. b 29. d 30. c
31. a 32. d 33. d 34. a 35. c 36. b 37. d 38. b 39. b 40. a
41. b 42. c 43. b 44. c 45. d 46. a 47. c 48. c 49. b 50. c
51. b 52. b 53. a 54. a 55. b 56. a 57. c 58. a 59. b 60. a
61. b 62. c 63. b 64. d 65. d 66. a 67. c 68. d 69. d 70. c
71. a 72. b 73. c 74. b 75. d 76. a 77. b 78. c 79. c 80. d
81. a 82. c 83. d 84. c 85. b 86. d 87. b 88. b _89. c 90. c
91. d 92. b 93. b 94. d 95. c 96. c 97. d 98. b 99. d 100.d
101.c 102.d 103.b 104.a 105.b 106. a 107.b 108.d 109.d 110.c
111.a 112.b 113.d 114.b 115. c 116.b 117.a 118.c 119.b 120.d
121.b 122.c 123.a 124.d 125. c 126. d 127.d 128.a 129.d 130.a
131.d 132.d 133.d 134.a 135. b 136. a 137.c 138.a 139.a 140.a
141.d 142.d 143.c 144.d 145.b 146.b 147.d 148.c 149.d 150. d
151.b 152. c 153.b 154. c 155. b 156. d 157. c 158. d 159. c 160. d
161. a 162. d 163. c 164. a 165. d 166. d 167. c 168. a 169. c 170. d
171.d 172.d 173.d 174.a 175.b 176. d 177.c 178.d 179.d 180.b
181.b 182.b 183.a 184.b 185. a 186.a 187.d 188.a 189.a 190.d
191.c 192.a 193.b 194.d 195. a 196.a 197.b 198.c 199.c 200.d
201. c 202.c

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