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Journal of Traumatic Stress

xxxx 2019, 00, 1–7

BRIEF REPORT
Nonsuicidal Self-Injury and Borderline Personality Features as Risk
Factors for Suicidal Ideation Among Male Veterans With
Posttraumatic Stress Disorder
Katherine C. Cunningham,1,2 Jessica L. Grossmann,3 Kathryn B. Seay,4 Paul A. Dennis,1,5
Carolina P. Clancy,1 Michael A. Hertzberg,1,5 Kate Berlin,1 Rachel A. Ruffin,1 Eric A. Dedert,1,2,5
Kim L. Gratz,6 Patrick S. Calhoun,1,2,5,7 Jean C. Beckham,1,2,5 and Nathan A. Kimbrel1,2,5
1
Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
2
The VA Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham, North Carolina, USA
3
VA Maryland Health Care System, Perry Point, Maryland, USA
4
VA San Diego Healthcare System, San Diego, California, USA
5
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA
6
Department of Psychology, University of Toledo, Toledo, Ohio, USA
7
VA Center for Health Services Research in Primary Care, Durham, North Carolina, USA

U.S. veterans are at increased risk for suicide compared to their civilian counterparts and account for approximately 20% of all deaths by
suicide. Posttraumatic stress disorder (PTSD) and borderline personality features (BPF) have each been associated with increased suicide
risk. Additionally, emerging research suggests that nonsuicidal self-injury (NSSI) may be a unique risk factor for suicidal behavior. Archival
data from 728 male veterans with a PTSD diagnosis who were receiving care through an outpatient Veterans Health Administration (VHA)
specialty PTSD clinic were analyzed. Diagnosis of PTSD was based on a structured clinical interview administered by trained clinicians. A
subscale of the Personality Assessment Inventory was used to assess BPF, and NSSI and suicidal ideation (SI) were assessed by self-report.
Findings revealed that NSSI (58.8%) and BPF (23.5%) were both relatively common in this sample of male veterans with PTSD. As
expected, each condition was associated with significantly increased odds of experiencing SI compared to PTSD alone, odds ratios (ORs)
= 1.2–2.6. Moreover, co-occurring PTSD, NSSI, and BPF were associated with significantly increased odds of experiencing SI compared
with PTSD, OR = 5.68; comorbid PTSD and NSSI, OR = 2.57; and comorbid PTSD and BPF, OR = 2.13. The present findings provide
new insight into the rates of NSSI and BPF among male veterans with PTSD and highlight the potential importance of these factors in
suicide risk.

U.S. military veterans account for only 8.5% of the U.S. pop- Veterans Affairs [VA] Office of Mental Health and Suicide Pre-
ulation but 20% of deaths by suicide each year (Department of vention, 2017). There are approximately 20 deaths by suicide
per day among veterans, 6 of which occur among veterans
currently using Veterans Health Administration (VHA) health
services (VA, 2017; Department of Veterans Affairs & Depart-
Manuscript preparation was partially supported by the Department of Veterans
Affairs (VA) Office of Academic Affiliations Advanced Fellowship Program ment of Defense [VA/DoD], 2013). Veterans face many risk
in Mental Illness Research and Treatment (Dr. Cunningham) and a Merit factors for suicide, including physical and mental health diag-
Award (I01CX001486) to Dr. Kimbrel from the Clinical Science Research noses (VA, 2017; VA/DoD, 2013), high rates of posttraumatic
and Development Service of the Department of Veterans Affairs Office of
Research and Development. The views expressed in this article are those of stress disorder (PTSD; Bullman & Kang, 1994; Sareen, Houli-
the authors and do not necessarily reflect the position or policy of the VA or han, Cox, & Asmundson, 2005), and nonsuicidal self-injury
the United States government or any of the institutions with which the authors (NSSI; Kimbrel et al., 2015, 2016).
are affiliated.
Approximately 21% of veterans seeking care from the VHA
Correspondence concerning this article should be addressed to Katherine C. are diagnosed with PTSD (Gates et al., 2012), and veterans
Cunningham, Ph.D., VA Mid-Atlantic Mental Illness Research, Education, and
Clinical Center, 3022 Croasdaile Dr., Durham, NC, 27705. E-mail: katherine- with a PTSD diagnosis are up to 4 times more likely to
cunningham@utulsa.edu. experience suicidal ideation (SI) than those without a PTSD
Published 2019. This article is a U.S. Government work and is in the public diagnosis (Jakupcak, Cook, Imel, & McFall, 2009). Notably,
domain in the USA. View this article online at wileyonlinelibrary.com PTSD shares symptom overlap (e.g., emotion dysregulation,
DOI: 10.1002/jts.22369

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Cunningham et al.

dissociation, and anger/irritability) with another robust risk fac- attempts than are other risk factors, including BPD (Klonsky,
tor for suicidal behavior, borderline personality disorder (BPD; May, & Glenn, 2013; Reibero et al., 2016). Of relevance to
American Psychiatric Association [APA], 2013). A small study the present study, Bryan and colleagues (2015) found that over
(n = 34, 53% psychiatric inpatients) conducted using diag- one-third of suicide attempts among their nonclinical veteran
nostic criteria from the revised third edition of the Diagnostic and military sample were preceded by NSSI following SI.
and Statistical Manual of Mental Disorders (DSM-III-R; APA, There is growing evidence that links PTSD, BPD, and NSSI
1980) suggested that as many as 76% of combat veterans with to suicidal ideation. Among an adolescent sample, NSSI was
PTSD also met criteria for BPD (Southwick, Yehuda, & Giller, shown to be associated with emotion dysregulation, suicidal
1993). This is consistent with findings of high co-occurrence ideation, and suicide attempts above and beyond the impact
between BPD and PTSD in community outpatient clinics of BPD (Glenn & Klonsky, 2013). Among women, the co-
(Harned, Rizvi, & Linehan, 2010), but it has not been replicated occurrence of PTSD and BPD has been associated with higher
with updated DSM criteria among diverse samples of veterans. levels of emotion dysregulation, NSSI, and suicidal behavior
Moreover, emerging research suggests that a sizable propor- than has BPD alone (see Harned et al., 2010). Despite these
tion of veterans with PTSD engage in NSSI (e.g., Kimbrel et al., findings, no study has, to our knowledge, examined these four
2014), which is defined as deliberate self-directed violence that variables together.
results in personal injury, without intent to die (Crosby, Ortega, Fluid vulnerability theory (FVT; Rudd, 2006) and the inter-
& Melanson, 2011). Examples of NSSI include, but are not lim- personal theory of suicide (IPTS; Joiner, 2005) are two com-
ited to, cutting, burning, or hitting oneself. Suicidal behavior plementary theories of suicide risk that help inform our un-
and NSSI are distinguished from one another by the presence or derstanding of PTSD, BPD, and NSSI as risk factors for SI
absence, respectively, of an individual’s desire and intent to die (see Bryan, Grove, & Kimbrel, 2017). The FVT posits that
by the action. For example, cutting oneself without desire and suicide risk fluctuates with dynamic changes across four cat-
intent to die is an example of NSSI, whereas engaging in cutting egories of risk and protective factors—cognitive, emotional,
with the desire and intent to die is a suicide attempt. Although physical, and behavioral. In addition to affecting each of these
NSSI is, by definition, functionally distinct from suicidal be- domains, PTSD, NSSI, and BPD are conditions that increase
havior, growing research suggests that NSSI is associated with individuals’ baseline risk, lower the activation threshold for
a heightened risk for suicide attempts and SI (Bryan, Bryan, crisis, and impair the ability to recover from crisis. The IPTS
May, & Klonsky, 2015; Hamza, Stewart, & Willoughby, 2012). suggests specific mechanisms that may affect these processes;
Indeed, a recent meta-analysis supported NSSI as the strongest namely, that the capability to engage in lethal suicidal self-
predictor of future suicide attempts but was unable to exam- injury is acquired through trauma exposure and engaging in
ine the effect of NSSI on SI due to the dearth of research that NSSI (i.e., by lowering fear of pain and death). Additionally,
has examined this question (Reibero et al., 2016). However, SI symptoms of all three conditions, including negative cognitions
was one of the strongest predictors of death by suicide, which (e.g., self-hatred, beliefs of worthlessness), emotional lability
highlights the importance of clarifying the association between (e.g., mood swings, extreme negative emotions, uncontrolled
NSSI and SI. anger), and disrupted relationships (e.g., social isolation, rela-
Among individuals with comorbid PTSD and BPD, NSSI tional discord), contribute to feelings of perceived burdensome-
occurs at high rates (e.g., Bentley, Cassiello-Robbins, Vittorio, ness and thwarted belongingness.
Sauer-Zavala, & Barlow, 2015), presumably due to the disor- Studies on these constructs have largely been conducted
ders’ shared association with emotion dysregulation (Chapman, with female civilian populations in community outpatient clin-
Gratz, & Brown, 2006). Indeed, the regulation of emotions, ics (e.g., Harned et al., 2010), and research that examines
including both relieving emotional pain (Klonsky, 2007) and BPD and NSSI among men is conspicuously lacking (Kimbrel,
increasing positive affect (Sacks, Flood, Dennis, Hertzberg, Calhoun, & Beckham, 2017). This has led to methods of NSSI
& Beckham, 2008), is among the most commonly endorsed commonly used by men (e.g., wall/object punching; Kimbrel,
functions of NSSI. Notwithstanding NSSI being among BPD Thomas et al., 2017) being overlooked. To our knowledge, no
criteria and a potentially associated feature of PTSD, NSSI has study has yet examined the prevalence of BPD or its associa-
been proposed as an independent diagnosis (APA, 2013; see tion with suicide risk among male veterans with PTSD. Thus,
Zetterqvist, 2015 for a review). Emerging evidence suggests the degree to which extant findings apply to military or male
NSSI disorder is comorbid at similar rates with multiple types of populations, particularly male veterans, remains unknown. This
psychopathology (e.g., Glenn & Klonsky, 2013; Gratz, Dixon- is a notable oversight given that recent research has observed
Gordon, Chapman, & Tull, 2015) and is associated with more high rates of both suicidal behavior and NSSI among male vet-
suicidal ideation and behavior (i.e., attempts; Glenn & Klonsky, erans (e.g., Bresin & Schoenleber, 2015; Hoffmire, Kemp, &
2013). Among veterans returning from Iraq and Afghanistan, Bossarte, 2015; Kimbrel et al., 2014).
NSSI has been found to predict current active SI above and The aims of the present study were to extend existing
beyond other risk factors, including mental health diagnoses research by examining PTSD, borderline personality features
(Kimbrel et al., 2014). This is consistent with past findings that (BPF), NSSI, and SI together among male veterans of the
have shown NSSI to be more strongly associated with suicide U.S. military. We did this by (a) documenting the rates of BPF

Journal of Traumatic Stress DOI 10.1002/jts. Published on behalf of the International Society for Traumatic Stress Studies.
Borderline Features, Suicidal Ideation, and PTSD

and current NSSI among male veterans with PTSD and (b) Borderline personality features. Borderline personality
examining the odds of experiencing SI associated with these features were measured using the Borderline Features Scale
phenomena. We hypothesized that BPF features and NSSI (BOR) of the Personality Assessment Inventory (PAI; Morey,
would each be significantly and independently associated with 1991). The PAI is a 344-item self-report measure of personality
SI and that the presence of both phenomena among veterans pathology. Respondents rate each item on a 4-point Likert-type
with PTSD would be associated with the highest odds of SI. scale. Raw scale scores on the PAI are converted to standard-
ized t scores with a mean of 50 and standard deviation of 10.
The BOR is composed of four subscales: Affective Instability
Method (BOR-A), Identity Problems (BOR-I), Negative Relationships
(BOR-N), and Self-Harm Behaviors (BOR-S). Each subscale
Participants
reflects a component characteristic of BPD. The BOR-A sub-
We analyzed archival data from 728 male veterans with a scale reflects emotional sensitivity, lability, and dysregulation;
diagnosis of PTSD who were receiving care through an outpa- BOR-I reflects elements of unstable identity, lack of purpose,
tient VHA specialty PTSD clinic between 2000 and 2014. The and feelings of emptiness; BOR-N captures history of unstable
VHA defines veterans as “a person who served in active mili- relationships and feelings of betrayal and abandonment; and
tary, naval or air service who was discharged or released from BOR-S measures impulsive engagement in high-risk activities,
service under conditions ‘other than dishonorable’” (VA, 2014, such as drug abuse, risky sexual encounters, and reckless finan-
2018). Former and current members of the U.S. National Guard cial decisions. It is important to note that the BOR-S subscale
and Reserves may be eligible for VHA services if they were is not an assessment of self-directed violence or suicidal be-
previously called to and served active duty other than train- havior (Morey, 2003). Previous research has shown that a BOR
ing (VA, 2018). Participants’ ages ranged from 20 to 86 years total scale t score greater than 65 is sufficiently sensitive and
(M = 48.69 years, SD = 12.31). The majority of participants specific to identify individuals with a clinical diagnosis of BPD
were non-Hispanic Black/African American (n = 336, 46.6%) (Jacobo, Blais, Baity, & Harley, 2007); however, due to the
or non-Hispanic White (n = 335, 46.0%). Approximately 3% shared features of BPD with severe PTSD, we used a highly
(n = 21) of the sample identified as Hispanic. The majority conservative cutoff score for BPF. Given that t scores above 70
of participants were married (n = 414, 56.9%) or divorced, on three or more BOR subscales are associated with increased
separated, or widowed (n = 226, 31.0%). All veterans were probability that patients will meet full diagnostic criteria for
diagnosed with PTSD, and 61.8% (n = 450) of veterans were BPD (Morey, 2003), the presence of severe BPF was estab-
diagnosed with co-occurring depression. lished by t scores greater than 75 on the BOR and greater than
75 on at least three of the four BOR subscales. Consistent with
previous research that has examined BPD and NSSI together,
Procedure
the self-injury criterion was retained in the BPF variable.
Diagnosis of DSM-IV-TR (APA, 2000) PTSD was based on a
structured clinical interview administered by trained clinicians. Nonsuicidal self-injury. Consistent with previous re-
Data were part of a standard initial evaluation for the PTSD search, five self-reported behavioral items were used to mea-
clinic, in which participants completed clinical interviews and sure NSSI, including severe scratching/skin picking, cutting,
a battery of self-report assessments. Storage and use of these hitting, burning, and wall/object punching (Kimbrel, Thomas
data for research purposes were approved by the institutional et al., 2017). With the exception of wall punching, these items
review board at the Durham VA Medical Center. Written in- reflect the Deliberate Self-Harm subscale (Sacks et al., 2008)
formed consent to use their data for research purposes was of the Habit Questionnaire (HQ; Resnick & Weaver, 1994).
obtained from each veteran prior to evaluation. Agreeing or de- This subscale distinguishes NSSI (i.e., deliberate self-directed
clining to participate did not impact veterans’ care. The present violence with the intent to injure) from body-focused repetitive
study did not include women veterans or male veterans who behaviors (i.e., habitual, repetitive behavior that may result in
did not receive a diagnosis of PTSD. Of the 871 male veterans injury). Wall and/or object punching was included because it
with PTSD who completed measures of the variables of inter- is a form of NSSI shown to be common among men (Kimbrel,
est, 138 (15.8%) were excluded due to invalid profiles on the Thomas et al., 2017). Respondents rated each item for lifetime
personality assessment obtained using standard cutoff scores presence (yes or no) and frequency within the past 2 weeks (not
(Morey, 2003), and five more were dropped from the analyses at all, once, two to four times, five or more times). Frequency
due to missing data on the outcome variable. within the past 2 weeks was coded dichotomously (absent vs.
present) to reflect current NSSI.
Measures
Suicidal ideation. Item 9 from the Beck Depression
Demographic information. Demographic information Inventory–II (BDI-II; Beck, Steer, & Brown, 1996) was used
was collected as part of standard intake. These data included to measure current suicidal ideation. This BDI-II item re-
age, gender, race, and marital status. flects the presence of “suicidal thoughts or wishes” in the past

Journal of Traumatic Stress DOI 10.1002/jts. Published on behalf of the International Society for Traumatic Stress Studies.
Cunningham et al.

Table 1 100%

Number of Veterans in Each Group and Proportion of Variable 90%


76%
Overlap 80%

70%
NSSI BPF 60%
55% 60%
52%
n Column %a n Column %a 50%
36%
40%
NSSI 304b 71.0 124c 72.5 30%
BPF 124c 29.0 47d 27.5 20%

10%
Note. Total N = 728 male veterans with posttraumatic stress disorder (PTSD).
PTSD only group, n = 253, 34.8% of total sample. NSSI = nonsuicidal self- 0%
PTSD PTSD+NSSI PTSD+BPF PTSD+NSSI+BPF Total Sample
injury; BPF = borderline personality features. (n = 90/253) (n = 167/304) (n = 28/47) (n = 94/124) (N = 379/728)
a Column % is the percentage of veterans exhibiting the column variable (i.e.,

NSSI or BPF) who are represented in each cell group. b PTSD+NSSI group. Figure 1. Percentage of veterans in each group who endorsed current suicidal
c PTSD+NSSI+BPF group. d PTSD+BPF group. ideation. PTSD = posttraumatic stress disorder; NSSI = nonsuicidal self-
injury; BPF = borderline personality features.

2 weeks. Respondents select the statement that best describes


their experience of suicidal ideation/intent from the following participants, and the PTSD+BPF group had 47 participants.
options: 0 = I don’t have any thoughts of killing myself, 1 = I Additionally, 253 participants did not endorse NSSI on the HQ
have thoughts of killing myself, but I would not carry them out, nor did they met the cutoff for severe BPF (i.e., PTSD-only
2 = I would like to kill myself, and 3 = I would kill myself if I group).
had the chance. This item was scored as a dichotomous variable Of the 428 veterans who reported current NSSI, approxi-
of self-reported absence (0) or presence (1–3) of any level of mately half (48.4%, n = 207) endorsed using multiple forms
SI within the past 2 weeks. of NSSI during the past 2 weeks. Wall/object punching was
the most commonly reported form of NSSI (68.7%, n = 294),
Data Analysis followed by severe scratching/skin picking resulting in injury
(60.1%, n = 257), hitting (26.9%, n = 115), burning (10.3%,
Univariate statistics and bivariate associations among vari- n = 44), and cutting (7.0%, n = 30). Over half of veterans in the
ables were examined prior to hypothesis testing. Logistic re- sample endorsed SI during the past 2 weeks (n = 379, 52.1%).
gression (SAS PROC LOGISTIC) was used to model the pres- All variables were correlated at p < .001.
ence of SI as a function of the presence of BPF and endorsement As illustrated in Figure 1, veterans in the PTSD+NSSI,
of current NSSI. Logistic regression provides odds ratios (ORs) PTSD+BPF, and PTSD+NSSI+BPF groups were signifi-
for the presence of SI based on group membership. Specif- cantly more likely to report current SI than those in the
ically, participants (i.e., male veterans diagnosed with PTSD) PTSD-only group. Logistic regression results are presented in
were identified as (a) not having severe BPF or any NSSI (PTSD Table 2. Membership in the PTSD+NSSI, OR = 2.21,
group), (b) having BPF but not NSSI (PTSD+BPF group), (c) 95% CI [1.57, 3.11]; or PTSD+BPF, OR = 2.66, 95% CI
not having BPF but engaging in NSSI (PTSD+NSSI group), [1.41, 5.05] group was significantly associated with current
and (d) demonstrating both BPF and NSSI (PTSD+NSSI+BPF SI. The odds of experiencing SI did not significantly differ
group). Each veteran was assigned to one group such that there
was no overlap in group membership. Differences in odds be-
tween groups are statistically significant when the associated Table 2
95% confidence interval does not span 1. Logistic Regression Analysis of Suicidal Ideation Among Male
Veterans With Posttraumatic Stress Disorder (PTSD)

Results OR 95% CI p

Table 1 presents the distribution of NSSI and BPF among PTSD+NSSI vs. PTSD 2.21 [1.57, 3.12] < .001
veterans with PTSD. The majority of veterans in the sample PTSD+BPF vs. PTSD 2.67 [1.41, 5.05] .003
(n = 599, 82.3%) reported at least one of these conditions. PTSD+NSSI+BPF vs. PTSD 5.68 [3.49, 9.22] < .001
Over half the sample (n = 428, 58.8%) endorsed engaging PTSD+NSSI vs. PTSD+BPF 1.21 [0.65, 2.26] .552
in at least one act of NSSI within the past 2 weeks. One- PTSD+NSSI+BPF vs. 2.57 [1.61, 4.12] < .001
quarter of the sample (n = 171, 23.5%) met the cutoff for PTSD+NSSI
severe BPF. There were 124 participants (17.0%) who endorsed PTSD+NSSI+BPF vs. 2.13 [1.04, 4.34] .038
both BPF and current NSSI (i.e., PTSD+BPF+NSSI group), PTSD+BPF
which represented 72.5% of those with BPF and 29.0% of those Note. NSSI = nonsuicidal self-injury; BPF = borderline personality features; OR
with current NSSI. The PTSD+NSSI group consisted of 304 = odds ratio.

Journal of Traumatic Stress DOI 10.1002/jts. Published on behalf of the International Society for Traumatic Stress Studies.
Borderline Features, Suicidal Ideation, and PTSD

between these groups, OR = 1.21, 95% CI [0.65, 2.26]. The this study may be generalizable to this population. Given the
PTSD+NSSI+BPF group exhibited the greatest odds for SI, relative lack of research, additional empirical questions abound.
OR = 5.68, 95% CI [3.49, 9.22], which was significantly higher Further research is needed to explore the presence and impact
than the odds observed for PTSD+NSSI and PTSD+BPF, of NSSI and co-occurring BPF/BPD among male veterans with
OR = 2.57, 95% CI [1.61, 4.11] and OR = 2.13, 95% PTSD. Because PTSD is associated with emotion dysregulation
CI [1.04, 4.34], respectively. and increased negative emotions, male veterans with PTSD may
use NSSI as a coping strategy for regulating intense negative
emotions. A recent study found that the criteria for complex
Discussion
PTSD in the 11th revision of the International Classification
Results of this study demonstrate the influence of NSSI and of Diseases (ICD-11) appears more strongly associated with
BPF on risk for SI among male veterans suffering from PTSD. BPD, self-harm, and SI than DSM-5 PTSD (Hyland, Shevlin,
Both NSSI and BPF were common, as more than half the sample Fyvie, & Karatzias, 2018). Research using DSM-5 and ICD-11
(58.79%) endorsed current NSSI and almost one-quarter of is needed to replicate and expand the present findings. Expand-
the sample (23.5%) had severe BPF. Notably, 71.0% of male ing our knowledge of the role of NSSI and BPF/BPD in the
veterans who endorsed NSSI did so in the absence of BPF, associated difficulties and trajectory of PTSD can improve care
which suggests that NSSI may also be an associated feature of for veterans with PTSD who are at risk for or are experiencing
PTSD. SI. Additionally, a better understanding of the impact of co-
Consistent with our hypothesis, NSSI and BPF were each in- occurring BPF/BPD among male veterans with PTSD and its
dependently associated with increased odds of SI, and there was association with suicide risk is essential for appropriate treat-
not a significant difference in SI between the PTSD+NSSI and ment planning and suicide-risk management. Further research
PTSD+BPF groups. Thus, NSSI alone or BPF alone conferred is needed to replicate and expand existing research that includes
equivalent risk for SI among the present sample. Although fur- variables that may also influence these associations. The inter-
ther research is needed, this finding suggests the relevance of relationships of PTSD, NSSI, and BPF/BPD should also be ex-
NSSI to SI among male veterans with PTSD, independent of amined among women veterans, who are at elevated risk for sui-
BPF. Given evidence that emotion dysregulation is a robust risk cidal behavior compared to their male counterparts (Hoffmire
factor for SI (e.g., Anestis, Bagge, Tull, & Joiner, 2011), this et al., 2015). It is possible that the associations between these
finding may reflect the heightened emotion dysregulation ob- variables may be different among veterans of different wartime
served in both BPF and NSSI. Unsurprisingly, the presence of eras. Research is needed to examine how such variations may
both NSSI and BPF among male veterans with PTSD conferred relate to clinical presentation and treatment needs. Overall, the
the greatest SI risk, as those in the PTSD+NSSI+BPF group findings of the present study provide new insight into the asso-
had 5.68 times the odds of experiencing SI than those with only ciations between NSSI and BPF and suicidal ideation among
PTSD. male veterans with PTSD and highlight the need for careful
The present findings should be interpreted within the context assessment and management of these factors.
of the study limitations. First, the use of cross–sectional, self-
report data did not allow for causal inference. Second, findings
from a sample of male veterans with PTSD cannot be general- References
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