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I. INTRODUCTION
Robot-assisted minimally invasive surgery (R-MIS) has
countless benefits over open surgery, from shorter recovery
times and lower risk procedures for the patient to higher ac-
Fig. 1. A)-B) Soft robotic haptic feedback glove prototype front view A)
curacy and broader capabilities for the surgeon [1]. However, and rear view B) showing adjustable straps wrapped across palm. C) CAD
a significant detriment to these procedures is that current R- model showing glove’s components, including finger actuators (numbered),
MIS systems lack haptic feedback. This forces the surgeon main glove structure with adjustable Velcro straps, and tubing. D) Soft
robotic sleeve showing three optical waveguides.
to depend merely on visual cues, such as the deformation
of tissue under load, to estimate the forces [1], [2]. The the presence of friction causes a reduction in rigid transmis-
likely outcome of misreading these cues is torn tissue, patient sion of forces from the contacted tissue to the surgeon [5]–
discomfort, or broken sutures [3]. In manual MIS surgeries, [7]. Thus, haptic feedback is vital for both conventional
surgeons interact with patients via rigid instruments with a and robot-assisted endoscopies. A recent study evaluating
long shaft, this reduces tactile and force feedback and leads an Endoscopic Operation Robot (EOR) concluded that the
to increased intra-operative injuries. In R-MIS surgeries, the absence of haptic feedback resulted in higher incidences of
tele-operated nature of robotic instruments removes the direct overstretching of the sigmoid colon in a colonoscopy training
tactile connection between the patient and the surgeon [4]. model [8]. Consequently, the lack of haptic feedback during
Lack of haptic feedback is particularly detrimental when colonoscopy results in application of excessive forces by the
the surgical instrument is flexible i.e, flexible endoscopes, as surgeon. This can cause tissue damage [9] and other severe
adverse events (SAEs) such as abdominal pain, bleeding,
*This work was supported by the National Institute of Biomedical perforation and splenic injury [10]. One study noted that the
Imaging and Bioengineering of the National Institutes of Health under
award number R21EB029154 and by the the National Center for Advancing peak pushing force during a colonoscopy exceeded 40 N,
Translational Sciences, National Institutes of Health, through BU-CTSI and forces were greater than 10 N for 5% of procedure
Grant Number 1UL1TR001430. Its contents are solely the responsibility time [11]. Another study observed that the peak force exerted
of the authors and do not necessarily represent the official views of the
NIH. on the colon wall was approximately 12 N, with an average
1 A. Gerald, R. Batliwala, J. Ye and S. Russo (corresponding author) are force value of 0.284 N [12]. Sensing systems have been
with the Mechanical Engineering Department, Boston University, Boston, developed to address the issues posed by excessive force
MA 02215 USA.
2 P. Hsu is with the Biomedical Engineering Department, Boston Univer- in colonoscopies, including distal tip force sensing [13],
sity, Boston, MA 02215 USA . shape sensing of the colonoscope using fiber Bragg gratings
3 H. Aihara is with Brigham and Women’s Hospital, Harvard Medical
(FBG) [14], and magnetic force tracking [15]. Feedback
School, Boston, MA 02115 USA. interfaces have also been utilized to mitigate application of
4 S. Russo is with the Materials Science and Engineering Division, Boston
University, Boston, MA 02215 USA. excessive forces during colonoscopy, such as a master-slave
E-mail: russos@bu.edu. telesurgical robot with haptic feedback [16], a sensorized
gripper providing audio-visual cues [17], and a virtual reality or electro-stimulation of a vibrotactile actuator does not
(VR) based haptic feedback simulator [18]. accurately represent the nature and sensation of the incident
Haptic feedback is normally provided via cutaneous inter- force produced in this scenario [32], [33].
actions to sensitive areas such as the palm and fingertips [19].
Thus, most devices that provide haptic or tactile feedback are The actuators on the fingers are attached to the main
in the form of gloves designed to be worn around the user’s glove piece in a modular fashion using adjustable Velcro®
hand [20]. However, most haptic feedback gloves cater to straps. This allows the glove to be quickly adapted to various
applications such as virtual or augmented reality (VR/AR), users’ hand sizes (i.e. interventional endoscopists). The finger
augmentative and alternative communication (AAC), and actuators are designed to be wrapped around the proximal
medical rehabilitation [21]. There appears to be a dearth of phalanges of the hand and inflate on the dorsal side (Fig. 1 A,
haptic feedback gloves used specifically for MIS, as most C). Similarly, the main glove piece is attached to the dorsal
existing MIS haptic systems are in the form of standalone side of the hand with a singular strap securing it across the
actuators or tactile arrays [22], [23]. Furthermore, most hap- palmar side around the wrist (Fig. 1 B). The components
tic feedback gloves largely utilize rigid commercial sensors of the glove do not cover the fingertips or interfere with
and actuators which hinder their flexibility [21]. This can grasping of the palm. This allows the surgeon to operate
be detrimental for surgical procedures which require precise the endoscope shaft and knobs without the glove hindering
and dexterous movements of the surgeon’s hand, ultimately palm and fingertip dexterity. Loss of such dexterity could
limiting the use of these devices in real clinical practice. A hamper handling and manipulation of the endoscope during
soft robotic haptic feedback glove would alleviate this issue the procedure. In contrast, most commercial haptic feedback
as it would provide improved mechanical compliance and gloves use vibrotactile or linear resonant actuators (LRAs)
flexibility compared to their rigid counterparts. However, cur- mounted onto the palm and fingertips [20]. This reduces palm
rent applications of soft robotic gloves have predominantly and fingertip dexterity, rendering such gloves unsuitable for
focused on robotic rehabilitation for stroke and spinal cord haptic feedback in endoscopies.
injuries [24]–[27]. The number of finger actuators in the proposed glove can
This work presents a soft robotic glove that aims at be varied depending on the number of sensors attached to
restoring and amplifying haptic feedback directly to the the endoscope. For the purpose of this study, such sensors
surgeon’s hand to facilitate navigation during colonoscopic are embedded in a soft robotic sleeve wrapped around a
procedures (Fig. 1, A-C). In our previous work, we in- colonoscope [28]. The soft robotic sleeve has three optical
troduced a soft robotic sleeve [28] that can detect forces waveguides to serve as force sensors, and each of them is
between a colonoscope and colon walls during navigation connected to a finger actuator (Fig. 1, C-D). Incident forces
(Fig. 1, D). The glove receives force input from the soft on each optical waveguide cause individual inflation of the
robotic sleeve wrapped around the colonoscope. Any incident corresponding actuator. The actuators are arranged on the
force on the sleeve, during endoscopic navigation, is relayed glove to match the spatial orientation of the sleeve, i.e, the
to the surgeon’s hand as haptic feedback through proportional first actuator on the index finger maps force input from the
inflation of the glove’s pneumatic actuators. first, leftmost waveguide (Fig. 1, C-D). Whereas the second
II. MATERIALS AND METHODS actuator on the middle finger maps force input from the
second, middle waveguide on the sleeve (Fig. 1, C-D).
This section describes the soft robotic haptic feedback Similarly, the third actuator inflates when there is incident
glove design, fabrication, and fluidic control circuit and force on the third, rightmost waveguide (Fig. 1, C-D). Thus,
associated pulse-width modulation (PWM) control approach. the surgeon is able to ascertain not only the magnitude of
A. Glove Design the incident force on the colonoscope but also its direction
based on the specific waveguide that detects the force.
The glove design consists of three pneumatic actuators,
each wrapped around the index, middle and ring fingers Overall, the glove is lightweight (30 g), with a low vertical
respectively, and connected the main glove piece (Fig. 1 C). profile of 1 mm and minimal wiring; three tubes measuring
Pneumatic actuation was selected as a viable method to 2.38 mm in outer diameter (OD) are attached to the three
deliver scalable haptic feedback directly to the surgeon’s soft pneumatic actuators. This ensures ergonomic comfort
hand. Compared to other methods such as electric motor for the wearer. The actuators also have a low vertical profile
and cable driven actuation, pneumatic actuation is more ad- (1.5 mm) when fully inflated. This reduces the risk of force
vantageous due to its high power-to-weight ratio, simplicity exchange between two touching actuators which could bias
of fabrication, low cost, and increased safety due to fewer the haptic feedback. In addition, the glove is designed to be
moving components [22], [29]–[31]. Furthermore, pneumatic disposable after each surgical procedure, thereby preventing
actuators provide a more natural sensation of haptic feedback any cross contamination. Flexible endoscopes and associated
compared to vibro-tactile actuators. For example, when a devices can become heavily contaminated with blood and
colonoscope presses against the colon wall, the surgeon secretions during use. This can potentially cause severe
feels a resistive force whose sensation can be mimicked infections in the patient [34], [35]. Hence, it is vital that
by pneumatic pressure. In contrast, the inherent vibration the device is easily replaced between surgical procedures.
Fig. 2. Soft robotic haptic feedback glove fabrication. A)-B) Heat weldable fabric and Teflon are laser cut into the desired pattern. C) Materials are
layered and laminated using double sided tape. D) Materials are sealed using heat press to form the completed soft actuator.
TABLE I
NASA TLX WORKLOAD SCORES FOR THE IN - VITRO TEST
relates to better efficiency and less discomfort. As seen This study describes an initial, proof-of-concept soft
in Table I, the workload score for the first test in which robotic haptic feedback glove for colonoscopies. The glove
haptic feedback was absent was 69.7, the highest of all four is linked to a soft robotic sleeve that allows force detection
tests. Moreover, mental demand, physical demand, effort, and between the colon and the colonoscope during endoscopic
frustration were rated as very high for the first test, which navigation. The glove is able to respond to incident forces
demonstrates the increase in discomfort for surgeons when on the colonoscope by inflating pneumatic actuators on the
no haptic feedback is present in colonoscopy procedures. In fingers, thereby providing haptic feedback to the surgeon.
the second test, with haptic feedback enabled and 100% The glove is made via a simple, sew-less fabrication process
sensor sensitivity, a workload score of 49 was achieved that allows inexpensive and rapid fabrication. The glove
(Table I). There was a significant decrease in the ratings for is controlled via a PWM control approach that determines
mental demand, physical demand, and frustration. Moreover, the duty cycle of the solenoid valves based on the optical
the performance parameter received a better rating for the loss from the soft robotic sleeve. The sensor is able to
second test compared to the first. This demonstrates the respond to forces greater than 1 N and achieves full inflation
effectiveness of the haptic glove in reducing workload and from 2.2 to 3 N, thereby alerting the surgeon to potential
burden on surgeons. For the third test, the sensor sensitivity dangerous forces in the colon. This range of forces can be
was reduced to 85% and the total workload score improved fine tuned in the future to account for the large variation
to 45.3 (Table I). Mental demand and physical demand in peak forces experienced during colonoscopic procedures.
were rated similar to the second test but the rating for The glove is able to effectively amplify incident forces by
frustration and effort decreased significantly, indicating a a factor of nine. This allows the glove to alert the surgeon
better experience by the subject. The subject also expressed using easily noticeable haptic cues. The glove was further
that 85% sensor sensitivity avoided unnecessary and minor evaluated in an in-vitro setting, wherein an expert surgical
pneumatic inflation (mainly reported during the insertion endoscopist rated the cumulative workload of a simulated
process), making the haptic glove more effective. For the colonoscopy procedure with and without haptic feedback. It
fourth and final test, the sensor sensitivity was reduced to was shown that haptic feedback from the glove significantly
70% and the resultant workload score increased to 57.7 reduced the workload of colonoscopic navigation from a
(Table I). The ratings for mental demand, physical demand, TLX value of 69.7 (without haptic feedback) to 45.3 (with
effort, and frustration were still lower than the first test with haptic feedback). We concluded that the glove is effective
no haptic feedback, but were higher than the second and third in pressurizing the fingers of the wearer proportionally
test. This suggests that keeping the scalar variable C in the to the amount of force exerted on a colon wall during
control logic at a value of 25 optimizes the effectiveness a colonoscopy procedure, providing haptic feedback. The
of the haptic glove system. The surgeon was aided by glove also provides a spatial mapping of the incident force
visual feedback in addition to haptic feedback due to the in different directions.
transparency of the TPE colon. However, visual feedback The next steps for this study would be to determine the
was present in both haptic feedback and no haptic feedback adaptability of the haptic glove to a larger pool of users
tests, serving as a control. with various skill levels (i.e., expert and novice interventional
endoscopists). Further, the glove could be adapted to provide [18] T. Wen, D. Medveczky, J. Wu, and J. Wu, “Colonoscopy procedure
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