Professional Documents
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12062
Abstract objective To assess the effectiveness of a training and supportive supervision intervention in
strengthening the capacity of pharmacy staff in Vietnam to deliver client-oriented, accurate healthcare
information and appropriate services for childhood diarrhoea and emergency contraceptive pills
(ECP).
methods Pre- and post-intervention study using a cross-sectional design. Pharmacy staff
participated in 3 days of training on customer relations, good pharmacy practice, childhood
diarrhoea and ECP over a period of 1 month, consisting of lectures, discussion, question-and-answer
sessions and role-playing. We compared baseline and 6-month post-intervention surveys to ascertain
changes in knowledge, attitudes and practice of pharmacists, using univariate statistics to find
significant differences.
results More than 1200 pharmacists received training and supportive supervision. After
interventions, pharmacy staff knowledge was significantly improved on most of the measured
indicators. Knowledge of dehydration symptoms for diarrhoea increased from 19% to 88%, and for
side effects of ECP increased from 27% to 77%. While assessment of actual practice revealed that
this knowledge was not always used, significant improvement was observed. Before interventions,
12% gave information on dehydration symptoms but 45% did so afterwards. The proportion giving
information on side effects of ECP increased from 13% to 54%.
conclusions Providing a programme of training and supportive supervision is an effective way to
improve knowledge and practice of pharmacists at private pharmacies in Vietnam. These
improvements have the potential to lead to better community health care.
keywords Vietnam, pharmacist, training, community health care, childhood diarrhoea, emergency
contraceptive pills, mystery clients
recommendations on the most effective types of interven- received an oral rehydration solution packet (UNICEF &
tions can be made. World Health Organization 2009).
The estimated number of drug outlets in Vietnam was In regard to use of emergency contraception, data on
more than 40 000 in 2011, excluding drug stores within abortions in recent years in Vietnam show that the rate is
commune health stations, with private pharmacies com- very high. About 1.4 million are performed annually and
prising nearly 12 000 of the total (Drug Administration the rate among married women aged 25–29 years is 0.40
of Vietnam 2012). Self-treatment is common, and phar- (Nguyen 2012). Surveys do not measure the rate for
macies are the most frequently used healthcare facilities, unmarried women, but data from national surveys sug-
accounting for approximately two-thirds of all health gest that young people in Vietnam are engaging more fre-
service contacts (World Bank et al. 2001). Several quently in premarital sexual relationships, with nearly
observational studies of pharmacies in Vietnam have 14% doing so in 2008 compared with 11% in 2003,
been reported. A study in Hanoi observed more than although their knowledge on reproductive health and
1800 customers at pharmacies and found that 95% pregnancy remained limited and unchanged (General Sta-
decided themselves which treatments to purchase and tistics Office of Vietnam 2009). The surveys also have
17% of these were antibiotics (Chuc & Tomson 1999). suggested that ECP is among the ‘best sellers’ of over-
Other studies on the quality of pharmacy practice the-counter drugs at private pharmacies. According to a
report that improvements are needed, especially in pri- report on incidence and trends in legal abortion world-
mary healthcare areas such as supplying antibiotics, wide from the Guttmacher Institute, ‘Where the abortion
managing STIs, treating diarrhoea in children, achieving rate is high, it likely reflects that levels of contraceptive
tuberculosis care and control and managing childhood use are not sufficient to meet the fertility desires and fam-
acute respiratory infection (van Duong et al. 1997; ily planning needs of women and couples’ (Sedgh et al.
Chalker et al. 2000; Chuc et al. 2001; Lonnroth et al. 2007).
2003). This article reports on strengthening the knowledge
Among the few intervention studies reported from and practice of pharmacists in delivering client-oriented,
Vietnam, a randomised trial in Hanoi (Chalker et al. accurate healthcare information and appropriate services
2002; Chuc et al. 2002) showed that knowledge and for childhood diarrhoea and ECP through a programme
reported practice of pharmacists who received training of training and supportive supervision.
and support improved significantly for syndromic treat-
ment of STIs and acute respiratory infections, appropriate
referrals and rational dispersal of drugs compared with a Methods
group that had no interventions. The interventions also
Study design and setting
included regulatory enforcement and a peer-influence
component. This was a pre- and post-intervention study using a
In 2008, the international non-governmental organisa- cross-sectional design. The interventions were training
tion PATH began a project with the ultimate goal of and supportive supervision of pharmacists, carried out in
improving health outcomes among community members selected urban areas in five provinces in Vietnam repre-
in five provinces in Vietnam through a public–private senting a diversity of geographical settings: Thai Nguyen,
partnership among provincial health authorities, pharma- Thua Thien Hue, Da Nang, Khanh Hoa and Vinh Long.
cies and public and private health facilities in the inter- Urban areas were chosen because the majority of private
vention area. Objectives of the project included pharmacies are found in these locations. Effects of inter-
strengthening the capacity of pharmacy staff to deliver ventions were measured by comparing knowledge, atti-
client-oriented primary healthcare information, services tudes and practice of pharmacists assessed in two types
and referrals; and increasing community awareness of of surveys before and after the interventions. Two coordi-
and demand for pharmacy-based primary healthcare ser- nators – one from the medical professional section and
vices for two health issues of community concern, child- one from the pharmaceutical management unit of the
hood diarrhoea and use of emergency contraceptive pills provincial health department – in each province served as
(ECP). While under-five mortality in general and deaths liaisons between the PATH team (two authors of this
from childhood diarrhoea have fallen in Vietnam, 10% article and two other staff) and all provincial partners.
of under-five deaths still were attributed to diarrhoea in Licensed private pharmacies in each province were
2010 (World Health Organization 2012). According to a mapped, and owners of all identified pharmacies were
2009 report, only 41% of children with diarrhoea invited to participate in 1-day technical update and orien-
received increased fluids for the condition and 26% tation workshops. Those who subsequently decided to
Randomly
selected
Randomly
1245 individual selected 789 individual staff
staff listed listed
Randomly
Randomly
selected
selected
Figure 1 Sampling process for pharmacy staff and mystery client surveys.
*During the time from registration until training started, a number of new pharmacies opened and asked to participate in the study.
After consultations with the Provincial Health Departments, these pharmacies gave written consent to participate and were included.
In each province, one supervisor was recruited from statistics (descriptions, frequencies, cross-tabulations, chi-
the provincial health department to attend the training squared test) to describe the characteristics of pharmacy
and to supervise the performance of the mystery clients. staff as well as to look for significant differences in the
Supervisors were responsible for seeing that all mystery knowledge level, attitudes and practice of pharmacy staff
clients visited their assigned pharmacies each day and for between the baseline and post-intervention evaluations.
screening all questionnaires completed by these clients. Statistical tests used an alpha of 0.05.
Because at least 90% of the pharmacy staff respon-
dents were either intermediate or assistant pharmacists,
Timeline of interventions and surveys
we did not perform subanalyses of results for participants
After pharmacies registered for the project, we conducted with different levels of education.
baseline surveys to ascertain the knowledge level and ser-
vice quality among pharmacy personnel. The baseline
Ethical issues
survey was conducted in June 2008 and the post-inter-
vention survey in January 2010. Training for pharmacy PATH’s Research Determination Committee approved
staff on the selected topics concluded 6 months before the survey protocols for non-research determination. We
the post-intervention survey (June 2009) (Table 1). asked all participants in the project to take part voluntar-
ily and gave all the right to withdraw at any time with-
out threat or disadvantage. PATH conducted the project
Data entry and analysis
in collaboration with officials from the five provincial
We computerised collected data using Microsoft Access health departments and the medical schools of each prov-
2003 and transferred data to Stata, version 11.0 (College ince. In Vietnam, for this type of study where the major
Station, TX, USA), for analysis. We used univariate interventions are training and supportive supervision or
Mapping pharmacies;
orientation workshops; Baseline Developing and printing Training of trainers; Supportive Post-interven-tion
Activity registration survey training and IEC materials training pharmacists supervision survey
quality assurance on public health issues for healthcare intervention survey across the five provinces. For the
professionals, there is no requirement for ethical approval baseline survey, numbers of respondents in each province
at the national level. In each of the five provinces, the were as follows: Da Nang: 53; Thua Thien Hue: 53;
project protocol was assessed for both technical and ethi- Thai Nguyen: 59; Vinh Long: 61; Khanh Hoa: 55. In the
cal aspects and received approval from the Provincial post-intervention survey, the number was 55 in each
People’s Committee for implementation. province.
Data showed a statistically significant improvement in
knowledge on childhood diarrhoea in all five provinces.
Results As can be seen in Table 3, the proportion of respondents
who knew dehydration symptoms after the interventions
Profiles of pharmacists
was more than four times that in the baseline evalua-
A total of 734 pharmacies in the five provinces partici- tions, increasing from 19% to 88%. Improvements were
pated in the project, with 396 owners and an additional observed in the proportions of post-intervention intervie-
890 staff trained, for a total of 1286 people working in wees with good knowledge on danger signs of diarrhoea
pharmacies who received training. Table 2 presents char- and diarrhoea prevention, reaching 94% and 93%,
acteristics of pharmacy staff who were interviewed. respectively. Only half as many respondents post-inter-
In the baseline and post-intervention surveys, grade 1- vention recommended antibiotics, a positive trend.
specialised pharmacists (post-graduate degree) and pharma- Table 3 also presents results of the two surveys regard-
cists (degree from a 4-year medical and pharmacy university ing ECP, showing that pharmacy staff knowledge
programme) comprised fewer than 10% of the interviewees. improved significantly after the interventions. After train-
80% of respondents were female, and the average length of ing, 77% of staff could name at least three side effects of
time staff had worked in pharmacy was 14 years. ECP compared with 27% at baseline. The number of
staff knowing when to use ECP after training more than
doubled.
Pharmacy staff surveys on knowledge of childhood
diarrhoea and ECP
Mystery client surveys of pharmacy staff for attitudes
We used structured questionnaires to gather information
and practice for childhood diarrhoea and ECP
from 281 pharmacy staff at baseline and 275 at the post-
Mystery client surveys allowed comparison of what phar-
Table 2 Characteristics of pharmacists surveyed macy staff said they were doing in direct questionnaires
with what they practiced when interacting with custom-
Participant Baseline Post-intervention
ers. For these measurements, mystery clients assessed 220
Gender N (%) N (%) staff at baseline and 220 after interventions (44 per prov-
Female 225 (80) 223 (81) ince). While 220 assessments were conducted, 3 question-
Male 56 (20) 52 (19) naires at baseline and 4 in the post-intervention survey
Professional degree
had missing or inconsistent information and were deemed
Pharmacist (post-graduate) 9 (3.2) 1 (0.3)
Pharmacist (university) 14 (5) 3 (1.1) invalid; these were excluded from the analyses. Table 4
Intermediate pharmacist 155 (55.2) 154 (56) shows changes in knowledge, attitude and skills among
Assistant pharmacist 99 (35.2) 114 (41.5) pharmacy staff after programme interventions. Overall,
Others 4 (1.4) 3 (1.1) 73% of mystery clients at the post-intervention evalua-
Age and experience Years Years tion reported that pharmacy staff had a positive attitude
Average age 41.6 40.8 (defined as ‘friendly, helpful, welcoming, or attentive’)
Average experience in 14.5 13.7
when asked about childhood diarrhoea, an improvement
pharmacy sector
from 59% at baseline. In regard to knowledge levels of
Table 3 Knowledge of pharmacy staff on childhood diarrhoea and ECP at baseline and post-intervention evaluations
Post-intervention%
Index Baseline% (n = 281) (n = 275) OR (95% CI)
Childhood diarrhoea
Knew 2 symptoms indicating diarrhoea 22 43 2.7 (1.8–4.0)
Knew 3 dehydration symptoms 19 88 32.4 (19.7–53.7)
Knew 3 danger signs of diarrhoea 49 94 15.9 (9.1–29.1)
Knew 3 means to prevent diarrhoea 57 93 10 (5.8–17.8)
Would recommend ORS* 97 99 2.6 (0.6–15.6)†
Would recommend antibiotics 15 7 2.3 (1.3–4.2)
Emergency contraception
Knew 3 side effects of ECP 27 77 9.2 (6.2–13.9)
Knew when to use ECP 41 85 8.4 (5.5–12.9)
Knew time to use ECP after unprotected sex 61 72 1.7 (1.2–2.4)
Table 4 Mystery client evaluation of pharmacy staff attitudes and practice for childhood diarrhoea and ECP at baseline and
post-intervention evaluations
Baseline% Post-intervention%
Index (n = 217) (n = 216) OR (95% CI)
Childhood diarrhoea
Pharmacist had positive attitude 59 73 1.8 (1.2–2.8)
Client understood information fromPharmacist 61 67 1.3 (0.9–1.9)†
Pharmacist asked about other symptoms 47 77 3.8 (2.4–5.9)
Pharmacist gave information on dehydration 12 45 5.8 (3.5–9.9)
Pharmacist gave information on danger signs 23 60 5.2 (3.3–8.1)
Pharmacist gave information on prevention 1 18 15.2 (4.7–78.0)
Pharmacist offered ORS* 42 88 10.1 (6.0–17.2)
Pharmacist offered antibiotic 15 4 3.9 (1.8–9.7)
Emergency contraception
Positive attitude 48 66 2.0 (1.4–3.0)
Client understood information from pharmacy staff 57 63 1.3 (0.9–1.9)†
Pharmacist gave information on side effects of ECP 13 54 8.3 (4.9–14.2)
Pharmacist warned ECP cannot protect against STIs 1 18 22.4 (5.6–193.2)
Pharmacist recommended regular contraception 8 46 10.4 (5.7–19.7)
methods instead of frequent use of ECP
pharmacy staff on childhood diarrhoea, more than 75% rhoea in children improved significantly, from 1% at
of mystery clients were asked by staff at the post-inter- baseline to 18% post-intervention, although this is still
vention evaluation about symptoms indicating diarrhoea very low. Notably, while staff self-reporting of recom-
in the child for whom they sought help, compared with mending ORS was much higher than that found by mys-
47% at baseline. In comparison with baseline informa- tery client survey, it did increase substantially after
tion, the practice of providing advice to prevent diar- intervention (Tables 3 and 4). Recommendations for anti-
biotic use were low in both staff survey and survey by training to staff at private pharmacies is an effective
mystery client at baseline and decreased after training way to improve pharmacy practice, which has the
as well. potential, ultimately, to improve community health
Mystery client surveys on ECP across the five provinces outcomes.
are also reported in Table 4 and showed a trend towards In our study, pharmacy staff improved their knowledge
improved attitude and skill in providing information. The of how best to care for clients with concerns about child-
proportion of staff with a positive attitude towards these hood diarrhoea or ECP after participating in training and
clients rose to 66% from a baseline of 48%. Among a programme of supportive supervision. Staff were also
other significant improvements were giving information significantly more likely to put this knowledge into prac-
on side effects of ECP and advising use of regular contra- tice when approached by customers after training,
ception methods instead of frequent use of ECP. although at a lower rate than indicated by direct ques-
tioning.
Questions arose in regard to some of our findings; for
Discussion and Conclusions
example, in the assessment of pharmacy staff knowledge
Because of the ubiquity of pharmacies in developing on childhood diarrhoea, knowledge improved substan-
countries and the number of people who obtain tially for identifying danger signs and dehydration symp-
medicines and advice there, these enterprises have a toms after training, but not so impressively for
substantial impact on public health. According to a identifying ‘symptoms indicating diarrhea’. The reason
review by authors from WHO and the World Bank, for this discrepancy is unclear, but in the mystery client
‘The private sector exerts a significant and critical assessment of practice for childhood diarrhoea, pharma-
influence on child health outcomes in developing cists were significantly more likely to ask about symp-
countries, including the health of poor children … toms and give information on dehydration and danger
Pharmacies, drug sellers, private suppliers, and food signs after training, so the training clearly had a positive
producers … have an impact on the health of children impact.
… governments and programmes that fail to integrate Our study had some limitations. First, there was no
these actors in child health policy and programmes will control group of pharmacies that received minimal train-
be seriously constrained’ (Bustreo et al. 2003). The arti- ing such as provision of printed information, or training
cle calls out training of pharmacists as a good strategy on another topic (Garcia et al. 2003). Further, we did
for contributing to child health outcomes. Other not arrange to assess the same individual staff via direct
publications from World Health Organization (1994) questionnaire and mystery client survey: while a pharma-
and the International Pharmaceutical Federation (1998) cist who answered a questionnaire also may have been
emphasise the role of pharmacists in the healthcare the subject of a mystery client visit, these coincidences, if
system. It follows that strengthening the knowledge and any, were not recorded purposively. However, the large
practice of pharmacists could improve public health, number of observations for both surveys provides confi-
although measuring the latter in large populations is dence that the interventions strengthened pharmacy prac-
difficult. tice in the survey populations. The questions in our
The study reported here is one of a few pre- and surveys were all open-ended – there were no questions
post-intervention studies that have compared knowledge with response options involving confirming a statement
and practice reported by staff as well as actual practice and no prompting by interviewers – minimising the possi-
and attitude of pharmacy staff measured by client bility of acquiescence response bias (Saris et al. 2010).
assessment in a developing country. Another study in Another limitation of the study was that we chose to
Vietnam (Chalker et al. 2002) trained pharmacists in 22 work with urban pharmacies, as the majority of pharma-
control and 22 matched intervention pharmacies and cies in Vietnam are located in urban areas. The results
showed significant improvement in the intervention thus may not be generalisable to rural and mountainous
group as measured by direct questionnaire, but had no areas of the country.
assessment for actual practice. We saw considerable dis- The fact that Vietnam has more than 40 000 drug out-
crepancies between pharmacists’ answers to direct ques- lets makes the task of improving practices at these facili-
tions and their practice assessed by mystery clients in ties daunting. While our study showed that interventions
our study, so it seems important not to rely only on at the private pharmacy level can produce change, clearly
reported practice. Our results add to evidence (Ross-De- the efforts must expand to improve pharmacy curricula
gnan et al. 1996; Chalker et al. 2002; Chuc et al. 2002; in colleges, thereby building correct practice into the
Garcia et al. 2003; Qidwai et al. 2006) that providing profession from the beginning.
the literature. International Journal for Quality in Health Care World Health Organization (1994). The Role of The Pharmacist
22, 316–323. in The Health Care System. World Health Organization,
World Bank, SIDA, AusAID, Royal Netherlands Embassy & Geneva.
Ministry of Health Vietnam (2001) Growing Healthy: A World Health Organization (2012). World Health Statistics
Review of Vietnam’s Health Sector. Ministry of Health, 2012. World Health Organization, Geneva.
Hanoi, Vietnam.
Corresponding Author Pham Duc Minh, PATH, 2nd floor, Hanoi Towers, 49 Hai Ba Trung Street, Hoan Kiem District, Hanoi,
Vietnam. E-mail: minhp1974@gmail.com