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2005-2013 Mercedes-Benz W221 and C216 Fuse Box Diagram

Fuse box in the engine compartment

No. Fused function A

Valid for engine 629, 642, 651:

   CDI control unit

20 10
Valid for engines 156, 157, 272, 273, 275, 276, 278:

   ME-SFI [ME] control unit

Valid for engines 156, 157, 272, 273, 275, 276, 278:

   Terminal 87 M1 i connector sleeve

Valid for model 221 with engine 629 and engine 642:

21    CDI control unit

20
   Fuel pump relay

Valid for model 221 with engine 651:

   Quantity control valve

Valid for engines 156, 157, 272, 273, 276, 278:

22 15
   Terminal 87 connector sleeve

23 up 2008:
20
   Terminal 87 connector sleeve

   Valid for engine 275 (model 216):

      Terminal 87 M1 i connector sleeve

   Valid for engine 273 (model 216):

       Terminal 87 M2e connector sleeve

   Valid for engine 272, 273 (model 221):

      Terminal 87M2i connector sleeve

   Valid for engine 642:

      Terminal 87 connector sleeve

from 2009:

   Valid for engine 156, 157, 272, 273, 275, 276, 278:

      Terminal 87 connector sleeve

   Valid for model 221 with engine 629 and engine 642:

      Terminal 87 connector sleeve

   Valid for engine 156, 157, 272, 273, 276, 278:

      Terminal 87M2e connector sleeve

   Valid for engine 275:

      Terminal 87 M2i connector sleeve

   Valid for model 221 with engine 629 and engine 642:

      Terminal 87 connector sleeve

   Valid for model 221 with engine 651:

      Rear SAM control unit with fuse and relay module

Valid for engines 157, 272, 273, 276, 278:

   Terminal 87M1e connector sleeve

24 25
Valid for engine 642:

   CDI control unit

25 Instrument cluster 7.5

26 Left front lamp unit 10

27 Right front lamp unit 10

Valid for engine 275:

   EGS control unit

28 7.5
Valid without engine 275:

   Fully integrated transmission control (VGS) control unit

29 Rear SAM control unit with fuse and relay module 5

Valid for engine 629, 642, 651:

   CDI control unit

30 Valid for engines 156, 157, 272, 273, 275, 276, 278:
7.5
   ME-SFI [ME] control unit
   Fuel pump control unit

31 S 400 Hybrid: Electric refrigerant compressor 5

Valid for model with ECO start/stop function:

   Transmission oil auxiliary pump control unit

32 15
S 400 Hybrid:

   Transmission oil auxiliary pump control unit

33 Valid as of 1.9.10 without model S 400 Hybrid:

5
   ESP control unit

S 400 Hybrid:

   Battery management system control unit

    DC/DC converter control unit

   Power electronics control unit

34 S 400 Hybrid: Regenerative braking system control unit 5

35 Electric parking brake controller unit 5

36 Data link connector (Pin 16) 10

37 For EIS control unit 7.5

38 Central gateway control unit 7.5

39 Instrument cluster 7.5

40 Upper control panel control unit 7.5

41 Slave wiper motor 30

42 Master wiper motor 30

43 Front cigar lighter with ashtray illumination 15

44 - -

45 S 400 Hybrid: Power electronics circulation pump 1 5

W221 with Active Body Control (ABC), model 216: ABC control unit

46 15
W221 without Active Body Contro (ABC): AIRmatic with ADS control unit

Front SAM control unit with fuse and relay module

47 15
Steering column up/down motor

up 2008: Front SAM control unit with fuse and relay module

48 15
from 2009: Steering column in/out motor

49 Steering column module 10

50 AAC [KLA] control unit 15

up 2008: COMAND display 7.5

51 from 2009:

   COMAND display
5
   SPLITVIEW display

W221: 

52
   Left fanfare horn
15
A
   Right fanfare horn

W221, C216: 

52
   Left fanfare horn
15
B
   Right fanfare horn

53 - -

54 AC air recirculation unit 40

55 Valid for gasoline engine: Electric air pump 60

56 W221 without Active Body Contro (ABC): AIRmatic compressor unit 40

up 2008: Wiper park position heater 40

57
from 2009: Wiper park position heater 30

60 from 2009: Electrohydraulic power steering 5

 61 C216; W221 - from 2009: Restraint systems control unit 7.5

W221; up 2008: Restraint systems control unit 10

62 Night View Assist control unit 5

Valid for model 221 with engine 629 and engine 642 as of 1.9.08: Fuel filter condensation sensor with heating
63 15
element

W221 as of 1.9.06:

   Driver NECK-PRO head restraint solenoid

7.5
   Front passenger NECK-PRO head restraint solenoid
64
W221 as of '09:

   Driver NECK-PRO head restraint solenoid

10
   Front passenger NECK-PRO head restraint solenoid

65 Valid as of 1.6.09: 12 Volt connector in glove box 15

66 DTR controller unit (Distronic or Distronic Plus) 7.5

Relay

A Air pump relay

B Air suspension compressor relay

C Terminal 87 relay, engine

D Terminal 15 relay

E Terminal 87 relay, chassis

F Fanfare horn relay

G Terminal 15R relay

H Circuit 50 relay, starter

J Circuit 15 relay, starter

K Wiper park heater relay

Left instrument panel fuse box



No. Fused function A

92 Left front seat control unit 40

Restraint systems control unit

93 7.5
USA version: Weight Sensing System (WSS) control unit

94 from 2009: Multifunction camera 5

95 - -

96 Tire pressure monitor [RDK] control unit 5

97 W221: Audio/video controller control unit (rear entertainment system) 7.5

98 Rear entertainment system: DVD player (from 2009) 7.5

from 2009:

99    COMAND display
7.5
   SPLITVIEW display

100 from 2009: Media interface control unit 5

101 Rear entertainment system:

10
    Left rear display

   Right rear display

102 Right front seat control unit 40

103 ESP control unit 7.5

104 Audio tuner control unit 40

105 - -

Japanese version: Electronic toll collection (ETC) control unit

106 Valid for South Korea as of 1.9.10: TV/tuner connector

1
Valid for navigation; from 2009: Navigation processor

SDAR control unit (SIRIUS satellite radio) (W221 from 2009)

107 Digital radio: Digital Audio Broadcasting control unit

5
HD radio: High definition tuner control unit

108 W221: Rear air conditioning control unit 5

109 W221: Rear blower intermediate connector 15

W221:

110    Left rear multicontour backrest control unit

7.5
   Right rear multicontour backrest control unit

111 Rear multicontour seat or rear entertainment system (model 221): RCP [HBF] control unit 5

W221; up 2008:

   Left front door control unit

112 5
   Right front door control unit

S 400 Hybrid: Front SAM control unit with fuse and relay module

113 S 400 Hybrid: DC/DC converter control unit 5

Right instrument panel fuse box



No. Fused function A

C216: Right door control unit

70 40
W221: Right front door control unit

71 Keyless Go control unit 15

72 S 400 Hybrid: Pyrotechnical separator 7.5

Japanese version: COMAND controller unit

73 5
TELE AID emergency call system (from 2009): Emergency call system control unit

74 TLC [HDS] control unit (Remote trunk closing) 30

S 400 Hybrid:

75    Battery management system control unit

10
   Power electronics control unit

S 400 Hybrid: Vacuum pump relay (+) 15

76
Valid for model 221 with engine 642.8: AdBlue® relay supply -

77 Advanced sound system: Sound amplifier (from 2009) 50

S 65 AMG with engine 275:

   Additional fan relay (from 2009)

25
Valid for model 221 with engine 642.8:

78
   AdBlue® relay supply (from 2009)

S 400 Hybrid, CL 63 AMG with engine 157, 278:

15
   Charge air cooler circulation pump (from 2009)

79 Alarm signal horn with additional battery 7.5

80 C216: Left door control unit

40
 W221: Left front door control unit

C216: Rear control unit 30

81
W221: Left rear door control unit 40

C216: Rear control unit 30

82
W221: Left rear door control unit 40

83 Intelligent servo module for DIRECT SELECT 30

84 Advanced sound system: Digital sound processor (from 2009) 20

85 Valid for AMG: Illuminated door sill moldings (from 2009) 10

86 - -

87 - -

88 - -

89 - -

Stationary heater:

90    STH heater unit (model 216)

20
   STH or HB heater unit (model 221)

Stationary heater:

   STH radio remote control receiver

91 5
S 400 Hybrid:

   Front SAM control unit with fuse and relay module

Fuse and relay box in rear

Opening: Swing down center armrest.

Open cover behind center armrest.

Pull cover 1 forward in direction of arrow.

Closing: Press cover 1 backward and engage

No. Fused function A

115 Heated rear window 50

Valid for engine 157, 275, 278: Charge air cooler circulation pump

116 Valid for engine 156: Engine coolant circulation pump

10
S 400 Hybrid: Power electronics circulation pump 2

117 Rear cigar lighter 15

Valid for engine 272, 273, 642: Fuel pump (up 2008)

30
Valid for model 221 with engine 629, 642: Fuel pump (from 2009)
118
S 400 Hybrid: Power electronics circulation pump 1

15
Valid for model 642.8 and engine 651 as of 1.6.11: Refrigerant compressor with magnetic

119 Front central operating unit 7.5

120 - -

121 Audio tuner control unit 10

122 COMAND controller unit 7.5

123 W221: Right front reversible emergency tensioning retractor 40

124 W221: Left front reversible emergency tensioning retractor 40

125 up 31.5.09: Voice control system (VCS) control unit 5

126 Overhead control panel control unit 25

127 Lumbar pump (from 2009)

30
Multicontour seat pneumatic pump (Left/right front multicontour seats)

Pneumatic pump for dynamic seat control (Left and right dynamic multicontour seat)
 Valid for engine 275 (up 2008): Fuel pump control unit

128 25
Valid for engine 156, 157, 272, 273, 275, 276, 278, 642 (from 2009): Fuel pump control unit

up 2008: Overhead control panel control unit (Power glass tilting/sliding roof)

129 25
from 2009: UPCI (Universal Portable Cell Phone Interface) control unit

130 Electric parking brake controller unit 30

131 Rear window antenna amplifier module 7.5

Trailer recognition control unit

133 15
Reversing camera (as of 1.9.10)

134 Luggage compartment socket 15

Park Assist; up 2008:

   Radar sensors control unit (SGR)

   Front short range radar sensor unit

135    Rear short range radar sensor unit

7.5
DISTRONIC PLUS up to 31.8.10 or Blind Spot Assist or Adaptive cruise control Plus Light: Radar sensors
control unit (SGR) (from 2009)

PARKTRONIC or Exclusive parking assist: PTS control unit

136 Valid for model 221 with engine 642.8: AdBlue® control unit 7.5

137 Reversing camera (as of 1.9.10) 7.5

Navigation processor (from 2009) (up to 31.8.10)

138 Emergency call system control unit (from 2009)

5
Japanese version: TV/tuner connector (from 2009)

139 Rear backrest refrigerator box 15

Rear cigar lighter with ashtray illumination connector

140 15
115 V socket (from 2009)

141 Reversing camera control unit 5

Parktronic system (PTS) control unit

Distronic Plus: Radar sensors control unit (SGR)

142 7.5
Valid as of 1.9.10 for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist:

   Video and radar sensor system control unit

143 Rear seats control unit 25

144 Rear seats control unit 25

Trailer recognition control unit (up 2008)

145 20
Trailer hitch socket (13-pin) (from 2009)

146 Trailer recognition control unit 25

147 up 2008: TLC [HDS] control unit (Remote trunk closing) 30

up 2008: Universal Portable CTEL Interface (UPCI [UHI]) control unit 7.5
148
from 2009: Panoramic sliding sunroof circuit 30 connector sleeve 25

up 2008: Voice control system (VCS [SBS]) control unit 5

149
from 2009: Panoramic sliding sunroof control module 25

150 TV combination tuner (analog/digital)

7.5
 Japanese version: TV/tuner connector (from 2009)

W221; up 2008: Electric parking brake controller unit 25

151
W221; from 2009: Trailer recognition control unit 20

W221: Rear window antenna amplifier module 7.5

152
115 V socket: DC/AC converter control unit 25

Relay

M Terminal 15 relay

N Terminal 15R relay

O Power outlet relay

P Heated rear window relay

Valid for engine 156, 157, 275, 278, 629: Circulation pump relay

Q
S 400 Hybrid: Valid for model 221.095/195: Power electronics circulation pump relay 2

R Cigar lighter relay

Fuel pump relay

Valid for engine 642.8 and engine 651 as of 1.6.11: Connected through the fuel pump: Refrigerant compressor
S
magnetic clutch

S 400 Hybrid: Power electronics circulation pump relay 1

Interior prefuse box (up 2008)

No. Fused function A

1 Starter 400

Not valid for engine 642:

   Alternator
150

2
Valid for engine 642:
200
   Alternator

3 - 150

4 AAC with integrated control additional fan motor 150

5 Valid for engine 642: PTC heater booster 200

6 Front SAM control unit with fuse and relay module 200
 7 ESP control unit 40

8 ESP control unit 25

9 Front SAM control unit with fuse and relay module 20

10 Vehicle power supply control unit 7.5

Interior prefuse box (from 2009)

No. Fused function A

3 Rear SAM control unit with fuse and relay module 150

ECO start/stop function:

   ECO start/stop function relay

S 400 Hybrid:

4 150
   DC/DC converter control unit

Heated windshield:

   Heated windshield control unit

Valid for model 221 (Electrical preinstallation for rental vehicle):Special vehicle multifunction control unit
125
5 (SVMCU [MSS])

S 400 Hybrid: Vacuum pump 40

6 Right dashboard fuse box 80

7 Valid for model 221 with engine 629, 642, 651:

150
   PTC heater booster

Valid for model 221 (Electrical preinstallation for rental vehicle):

   Special vehicle multifunction control unit (SVMCU [MSS])

 8 Front SAM control unit with fuse and relay module 80

9 Left dashboard fuse box 80

10 Rear SAM control unit with fuse and relay module 150

Engine compartment prefuse box (up 2008)

No. Fused function A

Front prefuse box

1 '
(via on-board electrical network line pyrofuse

2 Heated windshield control unit 125

3 Right instrument panel fuse box 80

4 Rear SAM control unit with fuse and relay module 200

5 Special vehicle multifunction control unit (SVMCU [MSS]) 100

6 Rear SAM control unit with fuse and relay module 150

7 Front SAM control unit with fuse and relay module 100

8 Left instrument panel fuse box 80

9 Front SAM control unit with fuse and relay module 5

10 C216: Emergency call system control unit 5

Engine compartment prefuse box (from 2009)

No. Fused function A

2 Alternator 400

Electrohydraulic power steering

3 Valid for model 221 with engine 629, 642:

150
   Glow time output stage

4 Interior prefuse box ( unfused) -

5 AAC with integrated control additional fan motor 100

6 Front SAM control unit with fuse and relay module 150

ESP control unit

7 40
S 400 Hybrid: Regenerative braking system control unit

ESP control unit

8 25
S 400 Hybrid: Regenerative braking system control unit

9 Front SAM control unit with fuse and relay module 25

10 Spare -

AdBlue fuse block

No. Fused function A

A AdBlue® control unit 7.5

B Heater circuit 1 20

C Heater circuit 2 20

D Spare -