The 

most frequent symptoms, which we had been mentioned in different articles, appear
because of an accumulation of histamine in tissues due to the activation of different histamine
receptors. These symptoms can be very diverse, such as: migraine, swelling, diarrhea and/or
constipation, hives, rhinitis and muscle and/or joint pain, among others.
In the last 15 years, it has been shown that the most appropriate treatment for these patients with
DAO deficiency is to follow a low-histamine diet prescribed by a specialized dietitian
and supplemented with DAO enzyme of animal origin, more specifically from pig kidney
protein extract. However, in countries like Germany or France, vegetal origin DAO enzyme is
already a reality. It represents a step forward to be able to recommend this enzyme to people
who follow a vegetarian/vegan diet or who for sociocultural reasons do not consume pork.
Currently, the main differences between the two origins are:

Animal origin DAO enzyme Vegetal or

Pork kidney extract Org

Same enzymatic activity as the anima

Good enzymatic activity and greater stability at temperature. Refrigeration recommended

More knowledge, both scientific and empirical

Promising alternative wi

Contains catalase naturally Contain

Available in the EU, USA and some countries in LATAM Available in

Not suitable for vegetarians nor vegans Suitable for