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A new, simplified technique for the quantitative

determination of levomycetin and anesthesin in the


presence of a sum of buckthorn-oil carotenoids in the
multicomponent preparation olazol has been developed
based on the modified Firordt method. The optimum
analytical wavelengths for the spectrophotometric
determination of levomycetin and anesthesin were found
by calculating the Kats-Rozkin informative coefficients. A
procedure has been elaborated that allows the
simultaneous quantitative analysis of both parent drugs in
the presence of buckthorn oil in olazol to be performed
without preliminary separation of components of this
complex preparation. The relative error of determination
is ± 3.2% for levomycetin and ± 1.0% for anesthesin. In
addition, the method of calculation of the content of
carotenoids (recalculated for β-carotene) is modified so as
to use a refined specific optical absorption index of β-
carotene.

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