MYOCARDIAL REPERFUSION INJURY

NAME
DAVID ALBERTO JONES PARDO

CODE
01200021024

PRACTICE INSITUTO CORAZON

UNIVERSIDAD DE SANTANDER, BUCARAMANGA

INSTRUMENTACION QUIRURGICA
2023
ACCORDING TO THE THEME TREATED IN THE ARTICLE, HE STATED THAT
MYOCARDIAL REPERFUSION IS AN ESSENTIAL PRACTICE TO INDUCE MYOCARDIAL
INJURIES SUCH AS PERFUSION ARRHYTHMIAS AND CARDIAC STUNNING.
HE STATEED THAT BEFORE THERE WERE NO EFFECTIVE THERAPIES FOR THE
PREVENTION OF HEART FAILURE FOR PATIENTS WHO HAVE BEEN SUBJECTED TO A
PERFUSION PROCESS, SO TODAY A BETTER UNDERSTANDING OF THIS
PHYSIOPATHOLOGY OF HEART FAILURE HAS RESULTED IN THE IDENTIFICATION
OF NEW THERAPEUTIC STRATEGIES SUCH AS RIC, HYPEROXEMIA AND AURICULAR
NATRIUTERIC TO POTENTIALLY PREVENT PATIENTS WHO HAVE BEEN SUBJECTED
TO A REPERFUSION PROCESS
TYPES OF MYOCARDIAL REPERFUSION INJURIES
REPERFUSION ARRHYTHMIAS
IN THE 1980s EXPERIMENTAL STUDIES WERE CARRIED OUT, WHERE IT WAS SHOWN
THAT ONE OF THE FIRST PATHOPHYSIOLOGIES PRESENT IN A SUBJECT AFTER
HAVING BEEN SUBJECTED TO A PERFUSION ARE VENTRICULAR ARRHYTHMIAS,
DURING THE STUDY IT WAS SHOWN THAT ARRHYTHMIA DUE TO REPERFUSION IS
OF THE MOST FREQUENT PATHOPHYSIOLOGIES IN PATIENTS
MYOCARDIAL STUNNING
THIS GENERATES A POST-CHEMIC CONTRACTILE DYSFUNCTION CAUSING
HARMFUL EFFECTS OF OXIDATIVE STRESS AND CALCIUM OVERLOAD AT THE
INTRACELLULAR LEVEL, DIRECTLY AFFECTING THE CONTRACTILE APPARATUS OF
THE HEART
MICROVASCULAR OBSTRUCTION
IT IS AN IRREVERSIBLE PATHOPHYSIOLOGY CAUSING MYOCARDIAL HEART
FAILURE WHICH CAUSES THE DEATH OF ENDOTHELIAL CELLS AND
CARDIOMYOCYTES (ABILITY TO REPERFUSION AN ISCHEMIC HEART)
IT COULD BE SAID THAT PERFUSION ALLOWS SURGERY TO PERFORM SURGERY
PROCEDURES TO RESTORE CERTAIN PATHOLOGIES, BUT THIS PROCESS GENERATES
SEQUELS THAT CAN AFFECT THE HEART WITH ANOTHER PHYSIOPATHOLOGY OF
GREATER OR LESSER MAGNITUDE

BIBLIGRAPHY

1. Myocardial reperfusion[Internet]. Oup.com. [citado el 25 de marzo de 2023].

Disponible en: https://academic.oup.com/eurheartj/article/34/23/1714/425646