Graber and Wilbur's Family Medicine Examination &Board Review, 4e >Pulmonology

Jason K. Wilbur, Mark A. Graber, Brigit E. Ray+

TABLE 3-1GENERAL INTERPRETATION OF PULMONARY FUNCTION TEST RESULTS COMPARING OBSTRUCTIVE AND RESTRICTIVE DISEASE (MAY NOT BE APPLICABLE FOR ALL FORMS OF
LUNG DISEASE)

PFT Result Obstructive Pattern Restrictive Pattern

FEV1 <80% predicted Decreased in proportion to loss of lung volume

FVC Decreased <80% predicted

FEV1/FVC <0.7 >0.7

FEF25–75% <60% predicted Decreased in proportion to loss of lung volume

TLC Normal or elevated Decreased

Decreased in intrinsic restrictive lung disease; normal in

DLCO Normal or elevated in asthma; normal or decreased in COPD
neuromuscular or musculoskeletal restrictive disease

FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FEF25–75, forced expiratory flow at 25–75% vital capacity; TLC, total lung capacity; DLCO, diffusing capacity of the lung for carbon
monoxide; COPD, chronic obstructive pulmonary disease.

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