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  • Additional Notes For Acute Phase Proteins

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    Johanna Marie
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    The document lists several acute-phase proteins that increase in concentration in response to inflammation. It provides information on the normal concentration, increase seen during the acute phase response, response time, and general functions of C-Reactive Protein, Serum Amyloid A, Alpha1-antitrypsin, Fibrinogen, Haptoglobin, Ceruloplasmin, Complement C3, and Mannose-binding protein.

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    ADDITIONAL_NOTES_FOR_ACUTE_PHASE_PROTEINS(3)

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    The document lists several acute-phase proteins that increase in concentration in response to inflammation. It provides information on the normal concentration, increase seen during the acute phase response, response time, and general functions of C-Reactive Protein, Serum Amyloid A, Alpha1-antitrypsin, Fibrinogen, Haptoglobin, Ceruloplasmin, Complement C3, and Mannose-binding protein.

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    7 views1 page

    Additional Notes For Acute Phase Proteins

    Uploaded by

    Johanna Marie
    The document lists several acute-phase proteins that increase in concentration in response to inflammation. It provides information on the normal concentration, increase seen during the acute phase response, response time, and general functions of C-Reactive Protein, Serum Amyloid A, Alpha1-antitrypsin, Fibrinogen, Haptoglobin, Ceruloplasmin, Complement C3, and Mannose-binding protein.

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    CHARACTERISTICS OF ACUTE-PHASE PROTEINS

    PROTEINS RESPONSE NORMAL INCREASE FUNCTION


    TIME (HR) CONCENTRATION
    (mg/dL)
    C-Reactive Protein 6 – 10 0.5 1000X Opsonization,
    (CRP) Complement
    activation
    Serum Amyloid A 24 3.0 1000X Removal of cholesterol
    Alpha1-antitrypsin 24 200-400 2-5X Protease inhibitor
    Fibrinogen 24 110-400 2-5X Clot formation
    Haptoglobin 24 40-200 2-10X Binds hemoglobin
    Ceruloplasmin 48-72 20-40 2X Binds copper and
    oxidizes iron
    Complement C3 48-72 60-140 2X Opsonization, lysis
    Mannose-binding ? 0.15-1.0 ? Complement
    protein activation

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