Professional Documents
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CASE REPORTS
CASE HISTORY 1:
Name : NA
Gender : Male
Education : NA
Occupation : NA
Chief complaints :
Hearing voices for the past 10 months
Loss of appetite
Physically abusive to his mother and sister.
Felt unsafe & people wanted to harm him
Duration :
10 months
Course of illness – unsafe, heard voices
Negative history:
No H/o suicidal thoughts
Biological history:
Not available
Family history:
Not available
Personal history:
Behavior from childhood- Introvert
Pre-morbid personality:
▪ Interpersonal relations – BAD
▪ Hobbies and interest – NA
▪ Subjective Mood – Repeated several times that there was nothing wrong with him.
▪ Habits
o Eating pattern – NA
TREATMENT:
The patient was prescribed with IM haloperidol 10 mg and IV diazepam 10 mg,
for rapid tranquilization when he was admitted due to aggression, this didn’t yield
any favorable results.
Changed to IM midazolam 7.5 mg and IM haloperidol 5 mg
Trihexyphenidyl 5 mg tablet was prescribed upon the recommendation of the
clinical pharmacists. The dose of olanzapine was also reduced to 5 mg upon
recommendation by the clinical pharmacists.
The patient underwent four cycles of electroconvulsive therapy with IV Ketamine
500 mg and IV haloperidol 10 mg. These were done on the 2 nd, 13th, 16th, and
18th days of hospital admission. The patient’s mood, appearance, behaviour,
perception, and insight improved while on therapy. Although he was occasionally
restless, he was mostly cooperative.
He was scheduled to be discharged on IM flupentixol 40 mg every 4 weeks and
olanzapine 5 mg tablet daily. The clinical pharmacists intervened for the dose of
IM flupentixol to be reduced to 20 mg. Therefore, the patient was discharged after
25 days of hospital admission on IM flupentixol 20 mg every 4 weeks and
olanzapine 5 mg tablet daily (to be tapered off in 3 months). The patient however
failed to report to the hospital for a psychiatric follow-up.
CASE HISTORY 2:
Name : NA
Age : 73 years
Gender : Female
Occupation : Clerk
Chief complaints :
Worsening memory impairment
Difficulty finding words
Duration :
A 73 year old woman was brought to neurological evaluation by her brother because of
a 3 year history of memory impairment. She had completed high school and worked in a
clerical position until her retirement in 1985. She had lived alone and maintained her
own home and financial affairs since the death of her husband in 1980. The brother had
begun to notice gradually worsening memory impairment and difficulty finding words,
but the patient became angry at the suggestion that she may have a progressive
impairment. Others had noted decline in housekeeping and financial affairs, but she had
no complaints.
Elevated arterial blood pressure was documented on several occasions, but she never
took medication. She had no children and had a hysterectomy. General and elemental
neurological exams were normal.
Negative history:
No H/o suicidal thoughts
Biological history:
Not available
Family history:
Not available
Pre-morbid personality:
▪ Interpersonal relations – GOOD
DIAGNOSIS:
On formal testing, she scored well below average in all cognitive
domains. These tests included the Wechsler Memory scale, the
Wechsler Adult Intelligence Scale, digit span and similarities
subtests, the Boston Naming Test, the CERAD Word List Memory
Test, the CERAD Visuo-spatial Construction, the Cross Circle
Tests, the California Proverb Test, and the Graphomotor
Alternation Test. She tended to perseverate both verbal and motor
responses
The conclusion of the evaluation was that she met research criteria
for "probable" Alzheimer's disease, that she required complete
supervision around the clock to insure her safety, and that she
would probably benefit from social stimulation provided by a
group living situation.
SUSHMITHA A | E20PC035