Professional Documents
Culture Documents
A PROJECT REPORT
submitted by
SARANYA.G (721917106073)
SARGADILEEPKUMAR.T.N (721917106074)
SWAPNA.P (721917106088)
YUVASREE.A (721917106097)
BACHELOR OF ENGINEERING
IN
APRIL2021
CERTIFICATE
ANNAUNIVERSITY : CHENNAI 600 025
BONAFIDE CERTIFICATE
SIGNATURE SIGNATURE
SUPERVISOR HEAD OFTHE DEPARTMENT
Mrs.S.G.RAMAPRIYANGA,M.E Mr.S.MUKUNTHAN M.TECH
Assistant Professor Assistant Professor,Head of the
Department of Electronics Department
and communication Department of Electronics and
Engineering Communication Engineering
Dhanalakshmi Srinivasan College Dhanalakshmi Srinivasan College
of Engineering of Engineering
Coimbatore- 641105 Coimbatore- 641105
INTERNALEXAMINER EXTERNALEXAMINER
ACKNOWLEDGEMENT
ACKNOWLEDGEMENT
i
TABLE OF CONTENTS
ABSTRACT I
LIST OF FIGURES V
LIST OF ABBREVATIONS VI
1 INTRODUCTION 1
1.1 Background of the study 2
1.2 Brain tumor detection 3
2 LITERATURE SURVEY 5
3 EXISTING METHOD 9
3.1 MRI segmentation methods 11
3.2 Methodology 12
3.3 Disadvantages 12
iii
13
4 PROPOSED SYSTEM
4.1 Advantages 14
15
4.2 Brain tumor detection block diagram
4.3 Description of brain tumor 15
4.3.1 Thresholding 16
4.3.2 Algorithm implimentation 16
16
4.3.4 Preprocessing
16
4.3.5 Classifying result
17
5 SYSTEM REQUIREMENTS SPECIFICATION
6 PROJECT REQUIREMENTS 19
iv
7 RESULT AND DISCUSSION 49
8 CONCLUSION 57
REFERENCES 59
v
LISTOF FIGURES
block diagram
7.2.2 Preprocessing 52
7.2.5.a Segmentation 54
7.2.5.b Segmentation 55
vi
LIST OF ABBREVIATIONS
ACRONYM ABBREVIATIONS
Transform
vii
CHAPTER 1
INTRODUCTION
1
CHAPTER 1
INTRODUCTION
2
tumor it gives to start the proper treatment and it may be curable. Therefore, the
treatments depend on tumor like; chemotherapy, radiotherapy and surgery.
Medical imaging is useful to diagnose the noninvasive possibilities.
3
to polarize and excite hydrogen nuclei (single proton) in human tissue, which
produces a signal that can be detected and it is encoded spatially, resulting in
images of the body. The MRI machine emits radio frequency (RF) pulse that
specifically binds only to hydrogen. The system sends the pulse to that specific
area of the body that needs to be examined. Due to the RF pulse, protons in that
area absorb the energy needed to make them spin in a different direction. This is
meant by the resonance of MRI. The RF pulse makes the protons spin at the
larmour frequency, in a specific direction. This frequency is found based on the
particular tissue being imaged and the strength of the main magnetic field. MRI
uses three electromagnetic fields: static field which is a very strong static
magnetic field which polarizes the hydrogen nuclei; gradient field which is a
weaker time-varying field used for spatial encoding; and a weak radio
frequency field for manipulation of the hydrogen nuclei to produce measurable
signals, which are collected through radio frequency antenna.
4
CHAPTER 2
LITERATURE SURVEY
5
CHAPTER 2
LITERATURE SURVEY
Brain tumour is a group of cell that grows abnormally in the cell, nerves and
other parts of the brain. Methods such as X-Ray, CT-Scan, MRI is available to
detect the brain tumour. It is necessary to find the accurate part of the affected
area of the brain tumour. Bio-medical image processing is the most challenging
and upcoming field in the present world. By using MATLAB, the tumour
present in the MRI brain image is segmented and the type of tumour is specified
using SVM classifier (Support Vector Machine). MRI of the brain for the image
segmentation using MATLAB used and specified the type of the tumour. To
segment tumour regions from MRI image, here an efficient algorithm called
threshold segmentation algorithm is used. This algorithm is mainly used for
segmentation process. It is performed by dividing the whole process into three
stages such as Pre-processing stage, Segmentation stage and Output stage. Pre-
processing stage consists of three steps. The first one is giving MRI input
image, second step is to convert it into the gray scale image and third step is to
enhance it using high pass filter. In the segmentation stage we use threshold
segmentation algorithm for segmentation of the tumour from the brain. The
third stage is the output stage where the tumour regions are segmented and
shown in output image. In this stage, we also use SVM classifier to identify the
type of tumour present in the brain.
6
2. Review on Brain Tumor Detection Using Digital Image Processing
7
4. Brain tumor MRI image segmentation and detection in image
processing
8
CHAPTER 3
EXISTING METHOD
9
CHAPTER 3
EXISTING METHOD
10
better results compared to existing available approaches in terms of accuracy
while maintaining the pathology experts’ acceptable accuracy rate.
3.1 MRI segmentation methods
Two different MRI segmentation methods that use multispectral image data
are proposed for the estimation of the volume of brain tumors. A supervised
k-nearest neighbor (kNN) and a semi-supervised fuzzy c-means (SFCM)
pattern recognition methods are used for the image segmentation. The
reproducibility of the two methods in determining the volume of different
tumors and the change in volume with therapy are estimated. The results are
compared with the volume estimates obtained by gray-level based seed-
growing method that is being used clinically. The results indicate that kNN
and SFCM methods should provide an accurate and reliable image
segmentation and tumor volume estimate, as required for treatment planning
and surgery simulation.
Tissue segmentation based on 2D and 3D feature maps derived from high
resolution MR images was performed in experimental brain edema in cats,
normal humans and those with brain tumors and MS. Statistical and
anisotropic diffusion filters were applied to the data. The k-nearest
neighborhood segmentation algorithm was utilized. Segmentation based on a
3D feature map was found to be much better than that based on a 2D feature
map (p<0.01). Inter-observer variability ranged between 6.6% and 9.3% and
intra-observer variability ranged between 8.3% and 10.4%. The use of high
resolution MRI resulted in detection of new lesions which well correlated
with neuropsychological exams. In conclusion, the presented technique is an
accurate, stable and promising method of tissue characterization
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3.2 METHODOLOGY
3.3 DISADVANTAGES
12
CHAPTER 4
PROPOSED SYSTEM
13
CHAPTER 4
PROPOSED SYSTEM
4.1 ADVANTAGES
Method which uses the kernel trick,so you can build in expert
knowledge about the problem via engineering the kernel.
14
4.2 BRAIN TUMOR DETECTION BLOCK DIAGRAM
Image Acquisition
Image
Acquisition RGB to gray
conversion
Thresholding
Tumor detection
Morphological operation
SVM classifier
Tumor detection
4.3 DESCRIPTION :
15
4.3.2 THRESHOLDING:
4.3.4 PREPROCESSING:
16
CHAPTER 5
17
CHAPTER 5
5.2.1 MATLAB2014a
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CHAPTER 6
PROJECT REQUIREMENTS
19
CHAPTER 6
PROJECT REQUIREMENTS
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6.1.1 RESOURCES REQUIRED:
FEASIBLITY STUDY:
The objective of feasibility study is not only to solve the problem but
also to acquire a sense of its scope. During the study, the problem definition was
crystallized and aspects of the problem to be included in the system are
determined. Consequently benefits are estimated with greater accuracy at this
stage. The key considerations are:
✓ Economicfeasibility
✓ Technicalfeasibility
✓ Operational feasibility
Economic Feasibility:
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Technical Feasibility:
Operational Feasibility:
This is the most important step of the feasibility study this study helps to
predict the operational ability of the system that is being developed. This study
also helps to analyze the approach towards which the system must be developed
by which development effort is reduced. Proposed system is beneficial only if
they can be turned into information systems that will meet the organization
requirements. This system supports in producing good results and reduces
manual work. Only by spending time to evaluate the feasibility, do we reduce
the chances from extreme embarrassments at larger stager of the project. Effort
spend on a feasibility analysis that results in the cancellation of a proposed
project is not a wasted effort.
practices. Grain grading and specification system assures that a particular lot of
grain meets the required set standards customer. In many countries grading of
grain depends on four main properties; (i) test weight (ii) moisture contents (iii)
broken foreign material or the percentage fragments example broken corn
foreign materials (iv) damaged kernels (i.e. total and heat damaged). There is no
proper definition or description of rice quality, because as definition of quality,
depends on several factors such cooking practice and region and usages for
example rice miller he/she describe rice quality in terms of total recovery and or
head and broken rice kernels while food processing will define concept of rice
quality in terms of grain size, aroma, appearance and cook ability. Common
physical properties of rice are size, shape, color, uniformity, and general
appearance. Other factors contributes to general appearance of rice are
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cleanliness, free from other seeds, virtuousness, translucency, chalkiness, color,
damaged and imperfect kernel. For the case of grain size, rice grain can be
categories into three main groups (i) length (ii) shape and (iii) weight.
EXISTING METHOD:
DISADVANTAGES:
PROPOSED METHOD:
In Proposed, SVM Classifier used to segment the cancer detected portion.
To segment the portion, first have to filter out the acquired image based upon
the masking methodology. The Morphological function including dilation and
erosion method will be applied extracted throughout the filtered image. By the
method of morphological bounding box will be drawn over the affectedportion.
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Then, the region enclosed by bounding box will be splitted out separately with
the SVM Classifier.
ADVANTAGES:
➢ Sensitivity to noise, blurring effects and miss registration.
➢ Due to the SVM Classifier usage the starting stage of brain tumor will be
find out.
➢ Method which uses the kernel trick, so you can build in expert knowledge
about the problem via engineering thekernel.
➢ It is an approximation to a bound on the test error rate, and there is a
substantial body of theory behind it which suggests it should be a good
idea.
Type of Testing:
1. Unconventional Testing
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2. Conventional Testing
Unconventional Testing:
1. Peer review
3. Inspection
4. Document Verification
Conventional Testing:
Unit Testing:
The primary goal of unit testing is to take the smallest piece of testable
software in the application, isolate it from the remainder of the code, and
determine whether it behaves exactly as you expect. Each unit is tested
separately before integrating them into modules to test the interfaces between
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modules. Unit testing has proven its value in that a large percentage of defects
are identified during its use. In the company as well as seeker registration form,
the zero length username and password are given and checked. Also the
duplicate username is given and checked. In the job and question entry, the
button will send data to the server only if the client side validations are made.
The dates are entered in wrong manner and checked. Wrong email-id and web
site URL (Universal Resource Locator) is given and checked.
Integration Testing:
Testing is done for each module. After testing all the modules, the
modules are integrated and testing of the final system is done with the test data,
specially designed to show that the system will operate successfully in all its
aspects conditions. Thus the system testing is a confirmation that all is correct
and an opportunity to show the user that the system works.
Validation Testing:
The final step involves Validation testing, which determines whether the
software function as the user expected. The end-user rather than the system
developer conduct this test most software developers as a process called “Alpha
and Beta Testing” to uncover that only the end user seems able to find. The
compilation of the entire project is based on the full satisfaction of the end
users. In the project, validation testing is made in various forms. In question
entry form, the correct answer only will be accepted in the answer box. The
answers other than the four given choices will not beaccepted.
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1. Testing begins at the component level and works “outward” toward the
integration of the entire computer-based system.
2. Different testing techniques are appropriate at different points intime.
3. The developer of the s/w conducts testing and for large projects,
independent test group.
4. Testing and debugging are different activities, but debugging must be
accommodated in any testing strategy.
Integration Testing:
It is just the vice versa of the Black Box testing. There we do not watch
the internal variables during testing. This gives clear idea about what is going
on during execution of the system. The point at which the bug occurs were all
clear and were removed.
In this testing we give input to the system and test the output. Here we do
not go for watching the internal file in the system and what are the changes
made on them for the required output.
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Interface Testing
Module Testing
Maintenance
The objectives of this maintenance work are to make sure that the system
gets into work all time without any bug. Provision must be for environmental
changes which may affect the computer or software system. This is called the
maintenance of the system. Nowadays there is the rapid change in the software
world. Due to this rapid change, the system should be capable of adapting these
changes. In our project the process can be added without affecting other parts of
the system. Maintenance plays a vital role. The system will able to accept any
modification after its implementation. This system has been designed to favour
all new changes. Doing this will not affect the system’s performance or its
accuracy. This is the final step in system life cycle. Here we implement the
tested error-free system into real-life environment and make necessary changes,
which runs in an online fashion.
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6.3 SYSTEM IMPLEMENTATION:
6.3.1 SOFTWARE OVERVIEW
Key Features
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6.3.2 NUMERIC COMPUTATION
• Fourier analysis
• Sparse matrices
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Acquiring Data
MATLAB lets you access data from files, other applications, databases,
and external devices. You can read data from popular file formats such as
Microsoft Excel; text or binary files; image, sound, and video files; and
scientific files such as net CDF and HDF. File I/O functions let you work with
data files in any format.
Using MATLAB with add-on products, you can acquire data from
hardware devices, such as your computer’s serial port or sound card, as well as
stream live, measured data directly into MATLAB for analysis and
visualization. You can also communicate with instruments such as
oscilloscopes, function generators, and signal analyzers.
Analyzing Data
MATLAB lets you manage, filter, and preprocess your data. You can
perform exploratory data analysis to uncover trends, test assumptions, and build
descriptive models. MATLAB provides functions for filtering and smoothing,
interpolation, convolution, and fast Fourier transforms (FFTs). Add-on products
provide capabilities for curve and surface fitting, multivariate statistics, spectral
analysis, image analysis, system identification, and other analysis tasks.
Visualizing Data
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Documenting and Sharing Results
You can share results as plots or complete reports. MATLAB plots can be
customized to meet publication specifications and saved to common graphical
and data file formats. You can automatically generate a report when you
execute a MATLAB program. The report contains your code, comments, and
program results, including plots. Reports can be published in a variety of
formats, such as HTML, PDF, Word, or Latex.
The MATLAB language provides native support for the vector and
matrix operations that are fundamental to solving engineering and scientific
problems, enabling fast development and execution. With the MATLAB
language, you can write programs and develop algorithms faster than with
traditional languages because you do not need to perform low-level
administrative tasks such as declaring variables, specifying data types, and
allocating memory. In many cases, the support for vector and matrix operations
eliminates the need for for-loops. As a result, one line of MATLAB code can
often replace several lines of C or C++ code. MATLAB provides features of
traditional programming languages, including f low control, error handling, and
object-oriented programming (OOP). You can use fundamental data types or
advanced data structures, or you can define custom data types. You can produce
immediate results by interactively executing commands one at a time. This
approach lets you quickly explore multiple options and iterate to an optimal
solution. You can capture interactive steps as scripts and functions to reuse and
automate your work. MATLAB add-on products provide built-in algorithmsfor
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signal processing and communications, image and video processing, control
systems, and many other domains. By combining these algorithms with your
own, you can build complex programs and applications.
Development Tools
Command Window –Lets you interactively enter data, execute commands and
programs, and display results
Additional tools compare code and data files, and provide reports
showing file dependencies, annotated reminders, and code coverage.
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Integration with Other Languages and Applications
From MATLAB, you can directly call code written in C, C++, Java, and
.NET. Using the MATLAB engine library, you can call MATLAB code from C,
C++, or FORTRAN applications.
Performance
34
you can use imaging devices ranging from inexpensive Web cameras to high-
end
Key features
35
Image Acquisition Toolbox simplifies the acquisition process by
providing a consistent interface across operating systems, hardware devices, and
vendors. The toolbox provides multiple ways to access hardware devices from
MATLAB and Simulink: the Image Acquisition Tool, a programmatic interface
in MATLAB, and a block for Simulink. Each workflow provides access to
camera properties and controls while enabling you to solve different types of
problems with the strengths of each environment
The Image Acquisition app enables you to work with image and video
acquisition devices and is well suited for interactive configuration of cameras.
You can browse all hardware devices available on your computer, change
device settings, select a region of interest (ROI), preview an acquisition, acquire
images and video, and record data. A preview window helps verify and
optimize your acquisition parameters by automatically reflecting any
adjustments made to camera properties in the video stream. The Image
Acquisition app serves as a starting point in the development of automated and
custom image acquisition and processing systems.
Session Logging
Session logging lets you track actions performed in the tool with a history of
command-line equivalent functions. In situations that require the same
configuration and control process for multiple trials and experiments, the
session log provides the ability to load settings to a common point and export
the code to a programmatic interface in MATLAB for furtherautomation.
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Data Logging and Export
You can log data to disk, memory, or both simultaneously with the Image
Acquisition app or programmatically at the MATLAB command line. You can
set a limit on memory usage to prevent overuse of resources in memory-
intensive applications. Data acquired with the tool can also be exported directly
to the Image Viewer app in Image Processing Toolbox for greater control over
visualization. In addition, you can:
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Connecting to Hardware
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Extensible Hardware Support
Adaptor Kit
Digital cameras like CCD or CMOS sensor are those which have the
direct connection with the PC using USB port. Meanwhile, analogue cameras
require a grabbing card for connecting with PC. In MATLAB, Augmented
Reality is currently used for capturing the live video streams of the real world. It
is directly interfaced with the PC (Image Processor), and MATLAB uses inbuilt
software called adaptors for accessing or communicating with thisdevice.
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The final stage of image processing is the machine control in which a
robot is controlled according to the details obtained from image analysis. For
example, if a robot needs to identify a ball, it captures images in front of it,
sends it to PC, and analyses it with the MATLAB program. If the image input
and program output are satisfied, then it detects it as a ball. Otherwise, it goes
on searching for a ball by this method.
Key Features
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single-precision and double-precision floating-point and signed and unsigned 8-
bit, 16-bit, and 32-bit integers.
There are several ways to import and export images into and out of the
MATLABenvironment for processing. You can use Image Acquisition Toolbox
to acquire live images from Web cameras, frame grabbers, DCAM cameras,
GigE Vision cameras, and other devices. Using Database Toolbox , you can
access images stored in ODBC-compliant or JDBC-compliant databases.
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Image Enhancement
Image Deblurring
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Deblurring Images Using a Regularized Filterrestoring a blurred and noisy
image using a constrained least square restoration algorithm.
For more flexibility and control, the toolbox supports profile-based color
space conversions using a color management system based on ICC version 4.
For example, you can import n-dimensional ICC color profiles, create new or
modify existing ICC color profiles for specific input and output devices, specify
the rendering intent, and find all compliant profiles on your machine.
Image Transform
Image transforms such as FFT and DCT play a critical role in many
image processing tasks, including image enhancement, analysis, restoration, and
compression. Image Processing Toolbox provides several image transforms,
including Radon and fan-beam projections. You can reconstruct images from
parallel-beam and fan-beam projection data (common in tomography
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applications). Image transforms are also available in MATLAB and Wavelet
Toolbox™.
Image Conversion
Image conversions between data classes and image types are a common
requirement for imaging applications. Image Processing Toolbox provides a
variety of utilities for conversion between data classes, including single- and
double-precision floating-point and signed or unsigned 8-, 16-, and 32-bit
integers. The toolbox includes algorithms for conversion between image types,
including binary, grayscale, indexed color, and truecolor. Specifically for color
images, the toolbox supports a variety of color spaces (such as YIQ, HSV, and
YCrCb) as well as Bayer pattern encoded and high dynamic range images.
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To speed up training and handle large data sets, you can distribute
computations and data across multicore processors, GPUs, and computer
clusters using Parallel Computing Toolbox™.
Key Features
Network Architectures
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Supervised Networks
Feed forward networks have one-way connections from input to output layers.
They are most commonly used for prediction, pattern recognition, and nonlinear
function fitting. Supported feed forward networks include feed forward back
propagation, cascade-forward back propagation, feed forward input-delay back
propagation, linear, and perception networks.
47
Elman, and Hopfield networks. The toolbox also supports dynamic training of
custom networks with arbitrary connections.
Unsupervised Networks
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CHAPTER 7
Brain tumor is an abnormal growth of cells within the brain or in the central
spinal canal. This system was tested to show performance of extensive
calculations of brain tumor area and brain area. The area of brain tumor is
obtained by counting the number of tumor pixels.Then calculation of the
average error value of brain tumors area and brain area. Error testing of tumor
extent is used to test how effective segmentation has been done. The first step
to start performing brain tumors is preprocessing first using the median
filtering. Median fitering works by moving the pixel value of the original
image to the middle pixel value. The purpose of the median filtering is to
maintain the edge of the image. Then thresholding is carried out to identify
tumors based on gray level distribution. Thresholding results are used as input
to find the largest area. This largest area is useful for separating tumors from
other tissues. Then the brain segmentation is carried out using the watershed
method which begins by marking the brain region and the outer region of the
brain. This marking is useful for distinguishing the brain region and the outer
region of the brain. Watershed give different color in the marked area. After
that, the removal of skull bones with cropping method.
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7.1 OUTPUT IMAGES
This is the first step of our proposed project .In this the data is been provided that
is the magnetic resonance images(MRI) that are been collected in their original
format’s that are (.ima, .dcm). Mostly the mri images are of .dcm (DICOM[13])
Digital imaging and communications in medicine. We have used file operations
fopen(), fclose() available in matlab to read MRI images. Here the gray scale MRI
images are been provided as input to the system.
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7.1.2 Preprocessing
FIG7.1.2 Preprocessing
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7.1.3 Morphological operation
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7.1.4 Discrete wavelet transform(DWT)
We can divide tumors in according to how exponentially they developed i.e. growth
rate, with lower-grade tumors often being begin and higher-grade tumors being
malignant. Based on interpolation of low frequency sub band images obtained by
discrete wavelet transform (DWT) and the input image, the brain tumor detection is
obtained by using Haar wavelet transform. Database image is also decomposed by
using Haar wavelet transform by two levels and this database image is compared with
the input image by using Mutual information principle. Both input image and database
image is decomposed into different sub bands by using DWT.
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7.1.5 Segmentation
Detecting an object from a background, we can break the image up into segments in
which we can do more processing on. This is typically called Segmentation. Brain
tumor segmentation is a brain tumor assisted diagnosis technology that separates
different brain tumor structure. the state-of-the-art algorithms with a full automatic
segmentaion are discussed. Finally, an assessment of the current state is presented
FIG7.1.5.a Segmentation
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FIG7.1.5.b Segmentation
7.2 Summary
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CHAPTER 8
CONCLUSION
57
CHAPTER 8
CONCLUSION
The brain tumor is one of the deadliest diseases in today’s world. So in order to find
the tumor tissues at the earliest stage using the proposed algorithm with the help of
MATLAB tool, the proposed system is developed by analyzing on the previous
system provides an idea over the segmentation and classification and an effective
algorithm is designed using MATLAB. MRI images are best suitable for brain tumor
detection. In this project, Digital Image Processing Techniques are important for brain
tumor detection by MRI images. The preprocessing techniques include different
methods like Filtering, Contrast enhancement, are used for image smoothing. The
preprocessed images are used for post processing operations like; threshold,
histogram, segmentation and morphological operation, which is used to enhance the
images and the type of brain tumor is specified using SVM classifier. So in order to
find the tumor tissues at the earliest stage using the proposed algorithm with the help
of MATLAB tool, the proposed system is developed by analyzing on the previous
system provides an idea over the segmentation and classification and an effective
algorithm is designed using MATLAB.
58
REFERENCES
[1] Huang Meiyan, Wei Yang, Wu Yao, Jiang Jun, Chen Wufan, and QianjinFeng, “Brain
Tumor Segmentation Based on Local Independent Projection-based Classification”, IEEE
Transactions on Biomedical Engineering, 2019
[9] H. B. Nandpuru, Dr. S. S. Salankar, Prof. V. R. Bora, MRI brain cancer classification
using support vector machine. 2014 IEEE Students' Conference on Electrical, Electronics
and Computer Science, 978-1- 4799-2526-1/14/$31.00 ©2014 IEEE
[10] A. Padma and R.Sukanesh, “SVM based classification of soft tissues in brain CT
images using wavelet based dominant gray level run length texture features”, middle-east
journal of scientific research, 2013, 13(7): 883-888
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