Ledesma, Annika Ysabelle S.
BSN III-M
DRUG MECHANISM OF ADVERSE EFFECTS
ACTION/SIDE
EFFECTS
Inhibits the effects of
GENERIC NAME: pyrogens on the heat-
paracetamol regulating regions of
the hypothalamus and
BRAND NAME causes sweating and
Tylenol panadol vasodilation m the
hypothalamus
CLASSIFICATION: Relieves pam by
Analgesic and reducing
Antipyretic prostaglandin
production in the
ROUTE: P.O central nervous
system (CNS),
DOSAGE:2.5ml however it has no
anti-inflammatory
FREQUENCY q4 BID properties, since it only
affects peripheral
For fever greater than prostaglandin synthesis.
37.3
09/16/22
INDICATION/CONTR NURSING RESPONSIBILITIES
AINDICATION
● nausea, Indication: >Observe the
● stomach pain, This medication is 10 rights of Medication administration
● loss of appetite, recommended for right patient, Right medication. dose, route, time, documentation. history
● itching, treatment of and assessment. Drug-drug interaction and Evaluation, refuse.education
● rash, painful and febrile and information
● headache, conditions. Such
● dark urine, as headache >check doctor's order
● clay-colored stools migraine, >Check the body temperature.
toothache
neuralgia, colds > perform handwashing.
and influenza, sore
throat, backache, > introduce drug to the patient or the parents of the patient and educate
rheumatic pain,and them about its purpose and, Importance
dysmenorrhea
> Provide the patient water before and after giving the medication
> Assist the patient in a sitting position
Contraindication >Monitor CBC, liver and renal
- Hypersensitivity functions
to the drug
Severe hepatic >Document the medication given (drug, time, dosage, frequency,route, and
impairment
- Severe active patient’s response).
hepatic disease
 References:

Paracetamol uses, dosage, side effects, warnings. Drugs.com. (n.d.). Retrieved September 15, 2022, from https://www.drugs.com/paracetamol.html

Comerford, K. C., & Durkin, M. T. (2021). Nursing 2021 drug handbook. 41st edition. Philadelphia, Wolters Kluwer.

DRUG MECHANISM OF ADVERSE INDICATION/CONT NURSING RESPONSIBILITIES

ACTION EFFECTS RAINDICATION

BRAND NAME: Suprax binds to specific ● diarrhea. Indication:

penicillin-binding
GENERIC NAME: Cefixime proteins (PBPs)
located inside the
CLASSIFICATION:
bacterial cell wall,
cephalosporin antibiotics causing the inhibition
of the third and last
ROUTE: P.O stage of bacterial
cell wall synthesis.
DOSAGE:l 3ml
FREQUENCY: BID
TIME:
● stomach This medication is > Observe the
pain. used to treat adults 10 rights of Medication administration
● gas. and pediatric patients right patient, Right medication. dose, route, time, documentation. history and assessment.
six months of age or Drug-drug interaction and
● heartburn. Evaluation, refuse.education and information
● nausea. older with
● vomiting. uncomplicated urinary >check doctor's order
tract infections caused
by susceptible isolates > perform handwashing.
of Escherichia coli and
Proteus mirabilis. > introduce drug to the patient or the parents of the patient and educate them about its purpose
and,
Importance
Contraindicated:
in patients with >.Monitor signs of allergic reactions and anaphylaxis, including pulmonary symptoms
cephalosporin (tightness in the throat and chest, wheezing, cough dyspnea) or skin reactions (rash,
hypersensitivity or pruritus, urticaria).
cephamycin
hypersensitivityAnaphy >Document the medication given (drug, time, dosage, frequency,route, and patient’s response).
lactic/anaphylactoid
reactions (including >.Notify physician or nursing staff immediately if side effects reactions occur.
 shock and fatalities)
have been reported
with cefixime. Cefixime
should be used
cautiously in patients
with hypersensitivity to
penicillin.

References:

WebMD. (n.d.). Common and rare side effects for Cefixime. WebMD. Retrieved September 15, 2022, from
https://www.webmd.com/drugs/2/drug-3778-7269/cefixime-oral/cefixime-suspension-oral/details/list-contraindications

Cefixime. Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). Retrieved September 15, 2022, from https://go.drugbank.com/drugs/DB00671

Comerford, K. C., & Durkin, M. T. (2021). Nursing 2021 drug handbook. 41st edition. Philadelphia, Wolters Kluwer.

DRUG MECHANISM ADVERSE EFFECTS INDICATION/CONTR NURSING RESPONSIBILITIES

OF ACTION AINDICATION

Diazepam is a Indication: > Observe the

GENERIC NAME: benzodiazepine to treat episodes of 10 rights of Medication administration
Diazepam tranquilizer with ● Sedation increased seizures right patient, Right medication. dose, route, time, documentation. history and assessment.
anticonvulsant, ● Fatigue (such as cluster or Drug-drug interaction and
sedative, muscle ● Confusion breakthrough seizures) Evaluation, refuse.education and information
● Anterograde
BRAND NAME:Diastat relaxant and amnesia in people who are >check doctor's order
AcuDial amnesic ● Depression already taking
properties 9,10,6. ● Ataxia medications to control > perform handwashing.
CLASSIFICATION: Benzodiazepines, ● Irritability their seizures. This
benzodiazepines such as ● Disinhibition product is only >Teaching and informing the patient or the patient's parents about the indication, side
diazepam, bind to ● Local injection recommended for effects, and Contraindication
receptors in site reaction short-term treatment of
ROUTE: IV various regions of ● Headache seizure attacks. > Assess the patient IV site for any swelling, bulging or and bruises
the brain and ● Tremor
DOSAGE:2mg spinal cord. This ● Dystonia Contraindication > To monitor respiratory and cardiovascular status, blood pressure, heart rate, and anxiety
binding increases ● Urinary retention
FREQUENCY PRN the inhibitory ● Incontinence Contraindications to symptoms in patients taking diazepam. With long-term use, monitor liver enzymes, CBC, and for
effects of ● Nausea diazepam include patients
gamma-aminobut ● Constipation with a known signs of propylene glycol toxicity, including serum creatinine, BUN, serum lactate, and osmolality
for frank seizure yric acid (GABA ● Diplopia hypersensitivity to
● Libido changes diazepam. Diazepam is gap. With critically ill patients, monitor the depth of sedation.
● Rash also contraindicated in
● patients under 6 months >.Document the medication given (drug, time, dosage, frequency,route, and patient’s response).
of age. Other
contraindications to
diazepam include patients
with severe respiratory
insufficiency, myasthenia
gravis, sleep apnea
syndrome, and severe
hepatic insufficiency. It is
permissible in patients
with open-angle
glaucoma receiving
appropriate therapy but is
contraindicated in acute
narrow-angle glaucoma

References:

Diazepam. Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). Retrieved September 15, 2022, from https://go.drugbank.com/drugs/DB00829
U.S. National Library of Medicine. (n.d.). Diazepam: Medlineplus drug information. MedlinePlus. Retrieved September 15, 2022, from
https://medlineplus.gov/druginfo/meds/a682047.html
DRUG MECHANISM ADVERSE INDICATION/CONTRAINDI NURSING RESPONSIBILITIES
OF ACTION EFFECTS CATION

BRAND NAME: Rocephin Binds to bacterial ● Nausea, Indications: > Observe the
cell ● Vomiting, treatment of Skin 10 rights of Medication administration
GENERIC membranes, ● pain in your and skin structure right patient, Right medication. dose, route, time, documentation.
NAME:Ceftriaxone inhibits cell upper infections, Bone and history and assessment. Drug-drug interaction and
wall synthesis stomach joint infections, Evaluation, refuse.education and information
CLASSIFICATION: that spreads >check doctor's order
Complicated and
cephalosporin antibiotics to your back > perform handwashing.
uncomplicated
ROUTE IV
● pale or urinary tract > introduce drug to the patient or the parents of the patient and
yellowed infections, educate them about its purpose and,
DOSAGE 1 GM + 50CC skin, Uncomplicated importance
● dark gynecologic >administer the right drug at the
FREQUENCY: OD ANST colored infections, including right dose
urine gonorrhea, Lower > check the patency of the IV site
● new or respiratory tract and IV line
worsening infections, intra- > have vitamin K ready in case
breathing abdominal hypoprothrombinemia occurs
problems infections, > do not mix ceftriaxone with any
(wheezing, septicemia, other antimicrobial drug
feeling short Meningitis, otitis > discontinue if hypersensitivity
of breath); a media. reaction occurs
blood cell Perioperative prophylaxis monitor ceftriaxone blood levels in
disorder- patients with severe renal impairment
● Headache Contraindications: and in patients with renal and hepatic
● chest pain, ● diarrhea from an impairment
● Dizziness, infection with > report severe diarrhea, difficulty
● Weakness Clostridium difficile breathing, unusual tiredness or
● severe bacteria. fatigue, pain at injection site
tingling ● a type of blood > document and record
disorder where the red
blood cells burst called
hemolytic anemia.
● liver problems.
● disease of the
gallbladder.
● severe renal
impairment.
 ● yellowing of the skin

References:

WebMD. (n.d.). Ceftriaxone Injection: Uses, side effects, interactions, pictures, warnings & dosing. WebMD. Retrieved September 15, 2022, from
https://www.webmd.com/drugs/2/drug-7013/ceftriaxone-injection/details