PUBLIC HEALTH NOTICE

February 26, 2023

Long Covid
BioMarkers - Diagnosis - Treatment

LONG COVID (PASC)

PAGE 2:
EMERGENCY DIAGNOSTICS BIOMARKERS,
DIAGNOSIS,
Post Acute Sequelae of Covid (PASC)/Long TREATMENT.
COVID may effect up to 30% of individuals, as
Antibodies,
well as overlapping with ME/CFS affecting 1-3
Chemokines, and
million a year.
disrupting the
PASC represents a healthcare and economic fractalkine pathway in
emergency that must be addressed. non-classical
monocytes.
Similar Pathologies may exist in patients with
Post-Vaccination Injury, Post-Lyme &
Fibromyalgia.

Symptoms exacerbated by S1 subunit of SARS-

CoV-2 spike protein's inclusion in non-classical
monocytes that may persist over a year.

Approach therapy using precision diagnostics

to target efficacious therapeutics.
LONG COVID
BIOMARKERS, DIAGNOSIS, REFERENCES:
TREATMENT Dr. Bruce Patterson

Long Covid is a very heterogenous disease. Viral RNA shedding

has been detected more than 87days in an individual with https://www.youtube.com/watch?
impaired CD8+ T-Cell responses. Low CD8+ has also been notated v=h2xyWiMS2Q0
as a result of infection, and is also associated with EBV and
chronic fatigue. Brain Fog, Shortness of breath, Myalgias, https://www.frontiersin.org/article
neuropathy, Insomnia overlap with ME-CFS. s/10.3389/fimmu.2021.700782/full
Still other symptoms include, POTS/Dysautonomia, Dizziness,
Tachycardia, Tinnitus, and other mental health related issues.
https://www.frontiersin.org/article
s/10.3389/fimmu.2021.746021/full
In General, Long COVID, ME-CFS, Post vaccination long haul,
and fibromyalgia will indicate IL-6, sCD40L, VEGF, & IL-10.
IL-13 & IL-4 indicate a Type 2 inflammatory response.
VEGF is highly indicated in vascular dysregulation
RESOURCES
*Neurologic Disability - Decrease in sCD40L, VEGF
**Dysautonomia - sCD40L, VEGF, GM-CSF
https://www.covidlonghaulers.com/
***Dyspnea (Breathing) - sCD40L, IL-2, GM-CSF, TNF

****Fatigue - sCD40L, IL-2, GM-CSF, TNF, VEGF

https://fwdquestionshere.com/
*****Cardiac - GM-CSF, IL-8 - (IL-8 also elevated in post vax)

CD16+ Monocytes - non-classical - express high level of CONTACT

fractalkine receptor - bind to fractalkine on endothelial cells -
initiate inflammation due to S1 - inflammation leads to type 1 American Foundation For
cytokines - IL-2 IFN Gamma are numerators of long haulers index - Informed Consent

Fractalkine receptor binding leads to angiogenesis via VEGF & E: fwdquestionshere@gmail.com

Vasodilation - resulting in “headfulness” headaches, migraines,

brain fog, tinnitus, hot/cold insensitivity, low blood pressure w/ W: fwdquestionshere.com

compensatory heart rate increases

Why do monocytes live so long? Fractalkine causes senescence

program that non-classical monocytes no longer undergo
apoptosis.

By blocking CCR5 pathway interrupts senescence pathway and

allows cells to die.

CCR5 - Maraviroc
TMPRSS2 - Ivermectin by weight
Spike Protein - Nattokinase 4k-6k units
Immune Support - Glutathione 500mg