FMGE Jan 2023 Recall Pharma - DR Siraj Ahmad

FMGE Jan 2023
Pharmacology Recall
Dr Siraj Ahmad
MD, Pharmacology
Q. A patient had chronic pain related to gout for a month and it
subsided after medication. What will be added for the excretion of uric
acid in urine:
a. Allopurinol
b. Febuxostat
c. Colchicine
d. Probenecid
Dr Ahmad’s Pharmacology
Insta: dr.sirajahmad_pharma
Telegram: t.me/drsirajahmad; t.me/fmgesolution
Q. Which of the following is mechanism of action of Allopurinol:
a. Xanthine oxidase inhibitor
b. DHFR inhibitor
c. Thymidylate synthase inhibitor
d. Phosphoribosyl transferase inhibitor
Q. A patient had history of night sweats and cough for last 2 month
and was brought to hospital. Work reveals pleural effusion and raised
level of Adenosine deaminase. Which of the following antibiotic will be
given in initial 2 months of therapy
a. Ethambutol
b. Linezolid
c. Streptomycin
d. Levofloxacin
Q. The shown graph shows this type of inhibition:
a. Uncompetitive inhibition
b. Competitive inhibition
c. Non-Competitive inhibition
d. Allosteric inhibition
Q. In a patient who developed pulmonary fibrosis, which of the following agent is
used decrease the progression of fibrosis:
a. Busulfan
b. Pirfenidone
c. Roflumilast
d. Ipratropium
Q. Which of the following statement correctly describes the
mechanism of action of Labetalol:
a. It decreases peripheral vascular resistance by directly acting at the
vascular smooth muscles
b. Beta plus Alpha receptor blocker
c. Dilates arteries and results in reflex tachycardia
d. Mainly a veinodilator
Q. Which of the following diuretics act at the site marked with arrow:
a. Hydrochlorothiazide
b. Furosemide
c. Acetazolamide
d. Spironolactone
Q. A patient on cancer chemotherapy developed neutropenia. Which of
the following is a WBC growth factor that can be used in this patient:
a. Filgrastim
b. Darbepoetin
c. Oprelevekin
d. Romiplostim
Q. A child consumed multiple iron tablets and brought to emergency
with vomiting and abdominal pain. Which of the following is antidote of
choice:
a. D-Penicillamine
b. Desferrioxamine
c. EDTA
d. BAL
Q. Which of the following drug activates PPAR alpha:
a. Gemfibrozil
b. Ezetimibe
c. Colestipol
d. Simvastatin
Q. Which of the following can be used in management of
chemotherapy induced nausea and vomiting:
a. Ondansetron, Dexamethasone, Aprepitant
b. Metoclopramide, Dexamethasone and Domperidone
c. Chlorpheniramine, Domperidone, Doxylamine
d. Prochlorperazine, Metoclopramide, Dexamethasone
Q. Which of the following agent will be used for treatment of diarrhoea
in a patient who was treated for colorectal carcinoma with 5FU and
irinotecan:
a. Ciprofloxacin
b. Ornidazole
c. Atropine
d. Loperamide
Q. Which of the following local anaesthetic agent can also be used as IV
regional anaesthetic agent:
a. Lidocaine
b. Dibucaine
c. Bupivacaine
d. Ropivacaine
Q. In a clinical trial a drug is found to have therapeutic index of 25.
Which of the following best describes therapeutic index of the drug:
a. Ratio between a dose producing lethality in 50% and Effect in 50%
b. Ratio between therapeutic dose and maximum lethal dose
c. It represents first pass metabolism and is calculated by duration of
action of drug by the half life of drug
d. It represents extent of drug absorption and is calculated by AUC
and time graph
Q. Which of the following is best for Acromegaly
a. Lanreotide Depot
b. Octreotide IV
c. Terlipressin Nasal
d. Somatostatin
Q. In patient who complains of generalised weakness and ptosis
consulted the physician. After neostigmine administration symptoms of
a patient is improved. Diagnosis
a. Myasthenia gravis
b. Multiple sclerosis
c. Guillain Barre Syndrome
d. Dermatomyositis
Q. Which of the following agent acts at the marked site in the image:
a. Aliskiren
b. Ramipril
c. Losartan
d. Spironolactone
Q. A patient on anti depressant therapy complained of some sexual
side effects. Which of the following anti depressant is least likely
associated with sexual side effects:
a. Bupropion
b. Fluoxetine
c. Escitalopram
d. Venlafaxine
Q. A female patient on lithium therapy developed symptoms of lithium
overdose. Which of the following statement is FALSE about lithium
overdose:
a. Haemodialysis is not useful in this patient
b. Lithium causes hypothyroidism
c. Lithium toxicity is increased by thiazide diuretics
d. It is teratogenic
Q. Which of the following is statement is correct about mechanism of
action of Dicumarol
a. It inhibits conversion of plasminogen to plasmin by inhibiting tissue
plasminogen activator
b. Act by inhibiting Vitamin K Epoxide Reductase which is a involved in
activation of clotting factor 2, 7, 9, 10
c. It chelates calcium and reduces calcium level in coagulation
cascade
d. It act by increasing AT 3 level which chelates factor IIa and Xa
Q. Which of the following factors contributes least towards
development of Mucormycosis:
a. Neutropenia
b. Prolong steroid therapy
c. Uncontrolled diabetes
d. Chronic antibiotic usage
Q. In patient with benign prostatic hyperplasia, which of the following agent is
used to control irritative urethral symptoms:
a. TURP
b. Partial prostatectomy
c. Water intake restriction
d. Alpha blocker
Q. A HIV patient presented with neck rigidity and seizure. CSF
examination confirms diagnosis of cryptococcal meningitis. Which of the
following anti fungal is the preferred agent in this patient:
a. Voriconazole
b. Liposomal Amphotericin B
c. Fluconazole high dose
d. 5 Flucytosine + Fluconazole
Q. Inhalational anaesthetic of choice in a paediatric patient:
a. Halothane
b. Isoflurane
c. Sevoflurane
d. Desflurane
Q. Which of the following statement is false about this image:
a. Drug B is more potent than C B C
b. Drug D is least potent A
Response
c. Drug B is more efficacious than A
d. Drug A is most efficacios D
log Dose
Q. Which of the following drug is represented by the shown image:
a. Epinephrine
b. Dopamine
c. Norepinephrine
d. Isoprenaline
Q. Which of the following correctly describes Dale’s reversal
Phenomenon:
a. Fall in BP upon giving epinephrine in a patient pre-treated with
phentolamine
b. Increased BP and HR upon isoprenaline administration
c. Decreased BP upon repeated ephedrine administration
d. Increased BP upon giving alpha blocker in patient pre treated with
beta blocker
Q. Which of the following agent decreases mortality in a patient with
chronic congestive heart failure:
a. Metoprolol
b. Furosemide
c. Torsemide
d. Dopamine
Thank You

FMGE Jan 2023 Recall Pharma - DR Siraj Ahmad

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