Meselson and Stahl conducted an experiment to prove that DNA replicates semiconservatively. They grew E. coli bacteria that incorporated heavy nitrogen isotopes into their DNA and then transferred them to normal growth media. After one round of replication, they found that DNA densities were intermediate between the old and new DNA, showing that each new strand contained one old and one new piece of DNA. This supported the semiconservative model of replication.
Meselson and Stahl conducted an experiment to prove that DNA replicates semiconservatively. They grew E. coli bacteria that incorporated heavy nitrogen isotopes into their DNA and then transferred them to normal growth media. After one round of replication, they found that DNA densities were intermediate between the old and new DNA, showing that each new strand contained one old and one new piece of DNA. This supported the semiconservative model of replication.
Meselson and Stahl conducted an experiment to prove that DNA replicates semiconservatively. They grew E. coli bacteria that incorporated heavy nitrogen isotopes into their DNA and then transferred them to normal growth media. After one round of replication, they found that DNA densities were intermediate between the old and new DNA, showing that each new strand contained one old and one new piece of DNA. This supported the semiconservative model of replication.
Read the book chapter entitled “DNA: The Carrier of Genetic Information”, subtopic
Meselson and Stahl verified the mechanism of semiconservative replication and
Semiconservative replication explains the perpetuation of mutations and answer the following questions:
1. Explain what a conservative replication is:
2. Explain what a dispersive replication is. 3. Explain the semiconservative property of the DNA replication. 4. How were Meselson and Stahl able to prove how the DNA molecule replicates? Explain their experiment.