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FINAL PREBOARDS EXAMINATION

MODULE 5
Pharmacy Licensure Examination
NAME:

INSTRUCTIONS: Select the correct answer for each of the following questions. Mark only one answer for
each item by shading the box corresponding to the letter of your choice on the answer sheet provided.

MULTIPLE CHOICES:

1. R.A 9999 was APPROVED into law on:

A. February 26, 2010 C. February 15, 2010
B. April 13, 2010 D. September 13, 1988
2. This equation shows the relationship between the vapor pressure and the absolute temperature
of a liquid.
A. Ideal gas equation C. Clausius-Clapeyron equation
B. Van der Waals equation D. Noyes-Whitney equation
3. Which law of thermodynamics states explains that the total energy of a system and its
immediate surroundings remains constant during any operations
A. 1st law B. 2nd law C. 3rd law D. None
4. The following are natural emulsifying agents, EXCEPT:
A. Tween 80 C. Agar
B. Acacia D. Gelatin
5. An ointment base which has the ability to absorb serous discharge
A. Hydrocarbon base C. Water – soluble base
B. Oleaginous base D. Water – removable base
6. A type of Van der Waals forces of attraction which involves the dispersion of charges to induce
polarity between non-polar molecules.
A. London C. H-bond
B. Debye D. Keesom
7. A satisfactory suppository base must meet all of the following criteria, EXCEPT:
A. it should be inert
B. it should dissolve or disintegrate rapidly in the body cavity
C. it should not melt <30˚C
D. it should have a wide melting range
8. Oleaginous base:
I. Anhydrous II. Washable III. Can absorb water
A. I only C. I and II only
B. III only D. I, II and III
9. A suppository base that produces dehydrating effect and irritation to tissues.
A. PEG C. wecobee
B. witepsol base D. glycerinated gelatin
10. Under R.A. 5921, cipher means:
A. a system of words or other systems arbitrarily used to present words
B. characteristic style or symbols kept from the knowledge of other or disclosed confidentially
to only or a few
C. a method of secret writing that substitutes other letters or characters of the letter intended or
transposes the letter after arranging them in stocks
D. a representation of words
11. The percentage concentration of Magnesium hydroxide present in Milk of Magnesia
A. 8 – 10 % C. 7 – 8.5 %
B. 5 % D. 20%
12. A non-enteric film formers
I. Shellac flakes II. Povidone III. Ethylcellulose
A. I only C. II and III only
B. I and II only D. I, II and III
13. The third step in the wet granulation method of manufacturing tablets?
 A. Compression C. Drying the granulation
B. Preparation of damp mass D. Screening the damp mass into pellets or granules
14. These are alcoholic or oleaginous solutions or emulsions of various medicinal substances
intended to be rubbed on the skin
A. Liniments C. Collodions
B. Lotions D. Fluidextracts
15. The lowest possible temperature to heat cacao butter.
A. 30 °C C. 35 °C
B. 33 °C D. 36 °C
16. It is a colorless to slightly yellow, clear, effervescent liquid having a sweet, acidulous taste and
lemon flavor.
A. Citric acid solution C. Ipecac syrup
B. Magnesium citrate solution D. Sodium lactate solution
17. Dimethylpolysiloxane polymer is a
A. defoaming agent C. antioxidant
B. preservative D. surfactant
18. Filling method for highly viscous products:
A. Volumetric filling C. Both A and B
B. Gravimetric filling D. Neither A nor B
19. An ingredient that is added to a tablet formula to improve flow properties into a die for
compression is known as:
A. disintegrant C. lubricant
B. glidant D. surfactant
20. Yellow Ointment is a hydrocarbon base. What is the synonym of Yellow Ointment?
A. White Petroleum Jelly C. Simple Ointment
B. Yellow Petrolatum D. Liquid Petrolatum
21. Which condition usually increases the rate of drug dissolution from a tablet?
A. increase in particle size C. used of ionized, or salt form of the drug
B. decrease in the surface area of the drug D. use of sugar coating around the tablet
22. This is the crystals lattice formation of NaCl.
A. Cubic C. Monoclinic
B. Hexagonal D. Triclinic
23. Which of the following drugs do not bind to plasma protein to any significant extent:
A. lithium C. diazepam
B. digoxin D. amitriptyline
24. Clay and silicon are the principal components of:
A. sintered glass candles C. cellulose ester membrane
B. asbestos pad D. unglazed porcelain
25. Which of the following statements BEST describes “lakes”?
A. Commonly used in the form of colloidal dispersions
B. Contains a specified dye content
C. It is suitable for coloring products which the moisture levels are low
D. They range from 50 -60% pure dye
26. Lattice defects affect which of the following characteristics of metals?
I. Hardness II. Strength III. Melting point
A. I only C. I and II only
B. III only D. I, II and III
27. Properties of coated compressed tablets, EXCEPT:
A. it masks the taste or odor of the drug
B. it may not affect the release rate of the drug
C. it protects the drug form moisture, light and air
D. it improves the appearance of the tablet
28. Percentage concentration of glycerin contained in glycerogelatin preparation?
A. 40% C. 15%
B. 35% D. 10%
29. Which of the following solutions can be prepared by solution with maceration?
A. Lemonade purgante C. Peppermint spirit
B. Strong Rose water D. Peppermint water
30. Chemical name of Bentonite magma:
A. Magnesium aluminum silicate C. Colloidal hydrated aluminum silicate
B. Zinc silicate D. Any of the choices
31. The members of the Council of Pharmaceutical Education includes, EXCEPT:
A. Undersecretary of Health Service C. Undersecretary of Education
B. Dean of the College of Pharmacy UP D. BFAD administrator
32. Cross-linked starch:
A. Croscarmellose C. Sodium starch glycolate
B. Crospovidone D. All of the choices
33. All are TRUE about iontophoresis, EXCEPT:
A. It induces an increased migration of ionic drugs into skin by electrostatic repulsion at the
 active electrode
B. It applies electric current or voltage to enhance the transport of molecules.
C. It eliminates GI incompatibility
D. It reduces side effects and interpatient variability
34. The following fruit flavors mask the bitter taste of drugs, EXCEPT:
A. Orange C. Cinnamon
B. Cocoa D. Maple
35. It is used as a component of film-coating solutions to enhance the spread of coat over tablets.
A. Levigating agent C. Antioxidant
B. Plasticizer D. Oxidizing agent
36. A dosage form commonly applied to weeping or oozing surfaces
A. Ointments C. Lotions
B. Creams D. Suppositories
37. The method of sterilization applicable to parenteral solutions that are destroyed or inactivated
by high heat.
A. Dry heat sterilization C. Membrane Filtration sterilization
B. Tyndallization D. Inspissation
38. What happened to Aminophylline once oxidized?
A. will form precipitate C. will form a gas
B. will form crystals D. will form straw color
39. Type of oleoresin obtained by incising the trunk of a tree.
A. Commercial resin C. Natural resin
B. Prepared resin D. Synthetic oleoresin
40. Abrasives, ingredients in dentifrices are noted for which of the following actions?
A. Providing flavor C. Removing plaque and debris
B. Cleansing via foaming detergent action D. Preventing dental caries
41. Type of glass used for buffered aqueous solutions with acidic pH
A. Type I glass C. Type III glass
B. Type II glass D. NP
42. Which of the following statements is true regarding Fluid bed dryer :
A. it is an equipment used for precise blending of dry – to – dry or dry – to – liquid materials
with short processing times.
B. This can produce a dry granulation from a wet powder mix
C. It is an equipment that can alternately combine and draw apart the tablet material
D. This equipment can produce a dried, finely divided particles by spraying a mist of liquid
through a heated chamber.
43. A tablet excipient that promotes the flow of the tablet granulation or powder by reducing friction
among particles.
A. diluents C. binder
B. glidants D. antiadherent
44. True about wet method of preparing emulsion
A. Also called 4:2:1 method
B. It is also synonymous with Continental Method
C. Emulsifying agent is mixed with the oil before the addition of water
D. Emulsifying agent is added to water to form a mucilage before the addition of an oil
45. What is the percentage dispersion of acacia in water?
A. 10% C. 15%
B. 20% D. 25%
46. Under RA 6675, which of these prescriptions shall be filled:
A. Violative Rx C. Erroneous Rx
B. Impossible Rx D. Both A and C
47. A plastic container that is extensively used as rigid packaging material and as the main
component of IV bags.
A. Polyethylene C. Propylene
B. Polyvinyl chloride D. Polystyrene
48. Which of the following is an otic preparation?
A. Cerumenex C. Benzedrex
B. Ocean Mist D. Lugol's Solution
49. These problems are caused by excessive moisture or the inclusion of substances with low
melting temperatures in the formulation.
I. capping II. Picking III. sticking
A. I only C. II and III only
B. I and II only D. I, II and III
50. A microcrystalline cellulose used as tablet disintegrant
A. Ditab C. Amberlite
B. Avicel D. Carboxymethylcellulose calcium
51. Which of the following statements BEST describes Enthalpy?
A. This is the heat required to raise the temperature of 1 mole of a substance by 1 degree
 B. This is the heat required to increase the internal energy and to perform work of expansion
C. This is the heat absorbed when a solid melts.
D. This is the heat involved in the complete oxidation of 1 mole of compound at 1 atm pressure.
52. This is defined as a bounded space or a definite quantity of substance that is under
observation.
A. Phase C. Mixture
B. System D. Colloidal dispersion
53. Increasing the temperature and reducing the pressure can separate the adsorbed gas from a
solid and it is a process called:
A. Adsorption C. Leaching
B. Desorption D. Diffusion
54. It contains sodium stearate which is used for its laxative effect.
A. theobroma oil C. polyethylene glycol
B. glycerin D. glycerinated gelatin
55. This is known as the volume of the spaces between particles.
A. Bulk volume C. True volume
B. Void volume D. None of these
56. The Consumer Act of the Philippines is:
A. R.A. 6675 C. R.A. 7394
B. R.A. 9165 D. R.A. 9257
57. A phenomenon where in a gel takes up liquid without an observable increase in volume.
A. Sweating C. Syneresis
B. Imbibition D. Swelling
58. Range of HLB value in the Griffin scale for O/W emulsifying agents.
A. 1-3 C. 3-8
B. 8-16 D. 16-18
59. Hydrophilic petrolatum is:
A. Oleaginous base C. Water-soluble base
B. Absorption base D. Water-removable base
60. This method of extraction allows the drug to slowly pass through a column using a suitable
solvent.
A. Infusion C. Percolation
B. Decoction D. Maceration
61. The intermolecular forces of attraction responsible for the solubility of non-polar molecules such
as Iodine in solution by the addition of salts.
A. Debye C. Keesom
B. Ion-dipole interaction D. Ion-induced dipole interaction
62. This refers to the substance that can provide water solubility and permeability to the film to
ensure penetration by body fluids and therapeutic availability of the drug.
A. Polyethylene glycol C. Castor oil
B. Polyoxyethylene sorbitan D. beeswax
63. A component of film coating solutions used to enhance the spread of coat over tablets, beads
and granules
A. Levigating agent C. Anti – oxidant
B. Plasticizer D. Humectant
64. Emulsion having an oleaginous internal phase and an aqueous external phase are referred as:
A. O/W C. W/O
B. W/O/W D. O/W/O
65. This is a the “shear thinning systems”
A. Dilatant C. Pseudoplastic
B. Rheoplastic D. Thixotropic
66. An act to promote, require, and ensure the production of an adequate supply, distribution, use
and acceptance of drugs and medicines identified by their generic names:
A. R.A 3720 C. R.A 9165
B. R.A 9502 D. R.A 6675
67. It is used to determine the Vapor pressure lowering of a substance
A. Isopiestic method C. Beckmann method
B. Cottrell apparatus D. Osmometer
68. This could address the viscosity characteristics of powders, fluids and semi – solids.
A. Rheology C. Porosity
B. Viscosity D. Micromeritics
69. The usual effective concentration of benzoic acid as preservative?
A. 0.01 – 0.02% C. 1-2%
B. 0.1-0.2% D. 10-20%
70. The colligative properties of a solution are related to the
A. pH of the solution C. total number of solute particles in the solution
B. number of ions in the solution D. number of unionized molecules in the solution
71. It describes the rate of drug dissolution from a tablet.
A. Fick’s law C. Noyes-Whitney equation
 B. Henderson-Hasselbalch equation D. Law of mass action
72. R.A. 3720 was made into law on:
A. September 13, 1988 C. June 22, 1963
B. March 30, 1972 D. June 23, 1969
73. Processes that give/s rubber closures less friction, to enable easier mechanical insertion onto
vials:
I. Siliconization II. Halogenization III. Carbonization
A. I only C. I and II only
B. III only D. I, II and III
74. Binder of choice for moisture-sensitive materials:
A. Starch paste C. Glucose solution
B. Ethylcellulose D. Gelatin solution
75. Component of plastic tubes that offers transparency and a high degree of product chemical
compatibility.
A. HDPE C. LDPE
B. Polyethylene terephthalate D. Polypropylene
76. A type of stability test, which involve temperatures in 10-degree increments. This test is
performed to identify the products of degradation of a product:
A. Stress test C. Real time Stability test
B. Accelerated Stability test D. All of these
77. A button which the user presses to activate the valve assembly for emission of the product.
A. mounting cup C. actuator
B. spring D. stem
78. It modifies the solubility of capsules and produces enteric effect.
A. Titanium dioxide C. glycerol
B. acacia D. methylcellulose
79. A suspension that appears as masses of gel, consist of floccules of small distinct particles.
A. mixtures and emulsions C. gels
B. magmas and milk D. lotions
80. The illegal cultivation, culture, delivery, administration, dispensation, manufacture, sale, trading,
transportation, distribution, importation, exportation and possession of any dangerous drugs
and/or controlled precursor and essential chemical:
A. illegal possession C. illegal selling
B. illegal cultivation D. illegal trafficking
81. In the extemporaneous preparation of a suspension, levigation is used to:
A. reduce the zeta potential C. avoid bacterial growth
B. reduce particle size D. enhance viscosity
82. Similarity of Sprits and Elixirs:
A. Solute C. Solvent mixture
B. Sweetness D. Flavor
83. Which of the following methods is/are used in the preparation of effervescent salt?
I. Fusion II. Wet Granulation III. Compression
A. I only C. I and II only
B. III only D. I, II and III
84. Applicable S tax for retailer of Dangerous drugs.
A. S – 1 C. S – 4
B. S – 2 D. S – 3
85. A container which protects its contents from extraneous solids under normal conditions of
handling and shipment is:
A. Tight container C. Hermetic container
B. Well-sealed container D. Well-closed container
86. Component of closure that inserted in a cap to effect a hermetic seal between the closure and
the container.
A. cap C. liner
B. inner seal D. stopper
87. What is the effect of adding dissolved macromolecules into the aqueous phase of an emulsion?
A. decrease viscosity C. decrease creaming
B. increase viscosity D. decrease creaming
88. A problem encountered in tablet granulation in which the top of the tablet separates from the
whole because the filling material does not have enough time to bond after compression
A. Lamination C. Capping
B. Peeling D. Picking
89. Which of the following dose forms is specifically covered by the Federal Substance Labeling
Act?
A. Aerosols C. Parenterals
B. Tinctures D. Nitroglycerin tablets
90. Method used for the incorporation of small amounts of potent drugs with a large amount of
diluents.
A. Levigation C. Sifting
 B. Geometric dilution D. Tumbling
91. The device used in the measurement of consistency and viscosity of ointments:
A. Viscosimeter C. Penetrometer
B. Rheometers D. Lucimeter
92. This part of the sugar coating process is to round off tablet contours rapidly:
A. Syruping C. Subcoating
B. Sealing D. Polishing
93. Solubility term used when 1 part of solute dissolves in 1-10 parts of solvent:
A. Freely soluble C. Very soluble
B. Sparingly soluble D. Soluble
94. The non aqueous vehicle used in IM injection:
A. Glycerol C. Mineral oil
B. Peanut oil D. Alcohol
95. Preparations containing finely divided drug particles uniformly distributed throughout a vehicle
in which the drug exhibits a minimum degree of solubility.
A. Solution C. Emulsion
B. Suspension D. Elixir
96. For external use only:
A. Cod liver oil emulsion C. Milk of Magnesia
B. Boric acid D. Lugol’s solution
97. Combinations or mixtures of drugs which liquefy due to a lowering of their melting point:
A. Hygroscopic C. Efflorescent
B. Eutectic mixture D. Deliquescent
98. Any person, who shall import ________ unless authorized by law, shall be punished by
imprisonment from 12 years and one day to 20 years and a fine of 100, 000 pesos.
A. opium poppy
B. controlled precursor
C. essential chemical
D. Both B and C
99. Maximum penalty shall be imposed if the sale, trading, administration, delivery or distribution of
dangerous drug and/or controlled precursor and essential chemical transpires within ________
meters from school
A. 50
B. 75
C. 100
D. 125
100. Amount of morphine subject to life imprisonment to death penalty and a fine of 500,000 pesos
to 10M pesos:
A. 500g
B. 50g
C. 10g
D. 1g