Centro Escolar University

Makati Campus
1st Semester SY 2023-2024
EXAMINATION
IPS Pharmaceutical Dosage Form
Instruction: Shade the best answer. Shade letter E if no correct answer.
1. Used in tablet and capsule formulations to improve flow properties of the powder
mixture.
a. Tablet lubricant
b. Tablet glidant
c. Tablet disintegrant
d. Tablet opaquant
e. Tablet polishing agent
2. Used in tablet formulations to reduce friction during tablet compression.
a. Tablet lubricant
b. Tablet glidant
c. Tablet disintegrant
d. Tablet opaquant
e. Tablet polishing agent
3. It describes the passage of (drug) molecule through a membrane that does not
actively participate in the process.
a. Drug absorption d. Osmosis
b. Transport mechanism e. Dissociation
c. Passive diffusion
4. Drug substance physiochemical properties that influence bioavailability of oral drugs.
a. Particle size d. Hydration
b. Liquid solubility e. All of the above
c. Salt form
5. Site of sublingual route of administration
a. Rectal d. Spine
b. Under the tongue e. Bone
c. Heart
6. Tablet which has a smooth rapid disintegration when chewed or allowed to dissolved
in the mouth has a creamy base, usually of specially flavored and colored mannitol.
a. Sugar coated tablet
b. Enteric coated tablet
c. Buccal tablet
d. Chewable tablet
e. Sublingual tablet
7. Absorption bases obtained from the wool of sheep, is a purified waxlike substance
that has been cleaned, deodorize, and decolorized.
a. Petrolatum d. White ointment
b. Yellow ointment e. None of the above
c. Lanolin
8. The ideal powder characteristics for successful filling of hard gelatin capsules
include
a. Poor compatibility
b. Poor lubrication
c. Have adequate flow properties
d. Have low bulk density
9. The standard moisture content specification for hard gelatin capsules.
a. 13-16% w/w d. 10-16% w/w
b. 18-20% w/w e. 12-18% w/w
c. 13-20% w/w
10. This is the heat lost when the vapours condense to liquids
a. Heat of Condensation c. Heat of Vaporization
b. Heat of Fusion d. Heat of Fission
11. This is a surfactant that wen dissolved in water lowers the advancing contact angle
and aids in displacing an air phase at the surface and replacing it with a liquid phase
a. Detergent
b. Wetting agent
c. Solubilizing agent
d. Antifoaming agent
12. The resistance of fluid to flow is called
a. Liquidity c. Porosity
b. Bulkiness d. Viscosity
13. The upward movement of dispersed droplets relative to the continuous phase
a. Sedimentation c. Creaming
b. Coalescence d. Aggregation
14. Range of HLB value in the Griffin Scale for O/W emulsifying agents
a. 1 – 3 c. 8 – 16
b. 3 – 8 d. 16 – 18
15. The hydrocarbon base which is frequently used as a vehicle for ointment.
a. Cholesterol d. Sorbitan monostearate
b. Lanolin monooleate
c. Petroleum e. Mineral oil
16. Yellow ointment is a hydrocarbon base. What is the synonym for yellow ointment?
a. White petroleum jelly d. Simple ointment
b. Yellow petrolatum e. Liquid petrolatum
c. Petroleum jelly
17. It is frequently used as a diluent in the formulation of chewable tablet.
a. Mannitol d. Lactose
b. Celutab e. Sucrose
c. Avicel
18. What is the smallest capsule size?
a. 000 d. 1
b. 00 e. 5
c. 0
19. Commonly used lubricant in the formulation of tablets.
a. Lactose d. Celutab
b. Starch e. Magnesium stearate
c. Mannitol
20. Materials which help the tablet break up and dissolve to release the medicament are
called:
a. Anti-adherents c. Disintegrants
b. Solubilizing agents d. Diluent
21. Classification of temperature between 8C and 15C
a. Cold d. Warm
b. Cool e. None of the above
c. Controlled room temperature
22. Opacifying agent used in the production of opaque hard gelatin capsules
a. Titanium dioxide d. Lactose
b. Titanium oxide e. Starch
c. Zinc oxide

For ITEM 23-42: The questions and incomplete statements in this section can be
correctly answered or completed by one or more suggested answers. Choose the
answer, A-E.
23. Aromatic water is a type of solution, in which of the following described aromatic
waters?
I. Odoriferous portion of the plant with suitable purified water undergo
distillation. The distillate may require further clarification by re-
distillation
II. They are used mainly for their flavoring properties
 III. They are stored in a light-sensitive containers
IV. Also known as medicated waters, wherein volatile oils or other
volatile substances are mixed with an aqueous solute.
a. I, II, III and IV are correct
b. Only I is correct
c. III and IV are correct
d. I and II are incorrect
e. A, B, C and D are false
24. In which of the following describes the juices:
I. Prepared from fresh ripe fruit
II. Aqueous in character
III. Used as vehicle in making syrups
IV. Benzoic acid is used as preservative
a. I, II and III are incorrect
b. Only III and IV are correct
c. Only I and II are correct
d. Only IV is correct
e. A, B, C and D are false
25. Which statement/s about the advantages of elixirs is/are correct?
I. Flexibility and ease of dosage administration
II. More effective in masking the taste of drugs
III. This preparation can be given to pediatric patients
IV. Easier to swallow
a. I and II are correct
b. III and IV are correct
c. I and III are correct
d. II and IV are correct
e. Both A and C are the answer
26. Which of the following is/are example/s of Oral Solutions?
I. Citrate of Magnesia
II. Cloxacillin Na
III. Pedialyte
IV. Colyte
a. Only I is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, III and IV are correct
27. The particles in an ideal suspension should satisfy which of the following criteria?
I. Their size should be uniform.
II. They should be stationary or move randomly.
III. They should remain discrete
IV. Their size should under nanoparticles
a. Only I is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, III and IV are correct
28. Which of the following are components of Syrup?
I. Sucrose
II. Synthetic flavorant
III. Thickeners
IV. Co-solvents
a. Only I is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, III and IV are correct
29. Preservative added to syrup:
I. Glycerin
II. Sodium Benzoate
III. Benzoic acid
 IV. Methyl Paraben
a. Only I is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, III and IV are correct
30. Which of the following is/are a process of extraction?
I. Maceration
II. Digestion
III. Comminution
IV. Decoction
a. Only III is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, and IV are correct
31. The preservative/s for juices:
I. Benzoic acid
II. Sodium benzoate
III. Alcohol
IV. Glycerin
a. Only I is correct
b. Only II and IV are correct
c. Only I and III are correct
d. I, II and III are correct
e. I, II, III and IV are correct
32. Purpose of emulsions and emulsifications
I. Emulsion helps to render the oil more digestible and readily
adsorbed by deducing the diameter of the molecule of the external
phase of an oil globules.
II. Administration of distasteful oil by dispensing it in a sweetened,
flavored aqueous vehicle
III. It permits administration of liquid drugs into minute globules.
IV. It facilitates a relatively stable mixture of two miscible liquids.
a. Only I and IV are correct
b. Only II and III are correct
c. I, III and IV are correct
d. I, II and IV are correct
e. I, II, III and IV are correct
33. True about Surface-Tension theory
I. The use of surfactant increases the interfacial tension of two
immiscible liquids
II. Increasing the attraction between the liquids and increasing each
liquid repellent force for its own molecules.
III. Surfactants facilitate the breakup of large globules, which have a
lesser tendency to coalesce.
IV. Cohesive forces among liquid molecules are responsible for the
phenomenon of surface tension
a. Only I is correct
b. Only II is correct
c. I, III and IV are correct
d. II, III and IV are correct
e. I, II, III and IV are correct
34. Process of converting a liquid into vapor and condensing back to liquid is:
a. Sublimation
b. Condensation
c. Evaporation
d. Distillation
e. None of the above
35. The HLB system is used to classify:
a. Flavors
b. Colors
 c. Perfumes
d. Surfactants
e. None of the above
36. An aqueous solution which serves as a cleansing, or an antiseptic agent directed
against a part or into a cavity of the body is a/an:
a. Douche
b. Enema
c. Gargle
d. Spray
e. None of the above
37. Spans and Tweens are:
a. Phospholipids
b. Highly polymerized mannuronic acid anhydrides
c. Glycoside
d. Polyoxyalkalene derivatives
e. None of the above
38. Official forms of water include:
a. Water for injection
b. Bacteriostatic water for injection
c. Sterile water for injection
d. All of the above
e. None of the above
39. Alcoholic and hydroalcoholic solutions prepared from vegetable materials or from
chemical substances, prepared usually by maceration and percolation.
a. Extracts
b. Tinctures
c. Fluidextracts
d. Elixirs
e. None of the above
40. Preparations containing finely divided drug particles uniformly distributed throughout
a vehicle in which the drug exhibits a minimum degree of solubility:
a. Emulsion
b. Suspension
c. Solution
d. None of the above
e. All of the above
41. Lugol’s solution is:
a. Strong iodine solution
b. Povidone-iodine solution
c. Potassium iodine oral solution
d. None of the above
e. All of the above
42. The following solvents are used in the preparation of oral solutions, syrups and
elixirs except:
a. Alcohol, USP
b. Purified water, USP
c. Propylene glycol
d. Ethylene glycol
e. None of the above

For item 43-46: Choose from the following:

A. HLB value of 15-20

B. HLB value of 13-16
C. HLB value of 7-9
D. HLB value of 1-3

43. Antifoaming agent

44. Solubilizing agents
45. Wetting agents
46. Detergents
For ITEM 47-51: Match the following statement to its corresponding answer:

47. Particle size and Sedimentation Rate

48. Surface area and Particle size a. Inversely proportional
49. Polarity and solubility b. Direct proportional
50. Log P and Lipophilicity c. No relationship
51. Drug molecular weight and
absorption

For ITEM 52-64: The questions and incomplete statements in this section can be
correctly answered or completed by one or more suggested answers. Choose the
answer, A-E.
52. All of the following statements are true regarding biologics, EXCEPT;
I. Biologic products must pass control requirements such as potency,
sterility, pyrogens and constituent materials.
II. Freezing is required in the storage of biologics.
III. Most biologics have an expiration date of a year or longer after the
date of manufacture.
IV. Biologics are generally administered by oral
V. Toxoids and Vaccines are biologics for active immunity
a. I, IV only
b. II, III only
c. III, V only
d. IV, V only
e. I, II, III only
53. Which of the following statements is correct?
I. Diapid nasal spray is used for the prevention and treatment of
perennial allergic rhinitis
II. Lugol’s solution contains sodium iodide as co-solute
III. Simple syrup can be prepared by percolation
IV. Calcium hydroxide Topical Solution is also known as Liquor
Carbonis Detergens
a. I, II only
b. III, IV only
c. I, II, III only
d. I, II, III and IV
e. II, III, IV only
54. In which of the following are true about Extended-release drug products?
I. They are designed to release the medication slowly
II. They reduced the need to consume the medication on a regular
basis
III. An extended release drug product tends to increase patient
compliance by reducing dosage frequency
IV. Risk of toxicity is one of the disadvantages of extended-release
dosage form
a. I, II only
b. III, IV only
c. II, III only
d. I, IV only
e. I, II, III and IV
55. All of the following statements are true regarding delayed-release dosage form,
EXCEPT:
I. Medications that are designed to release the active ingredient(s)
later after taking it.
II. Controlled-release dosage forms are common delayed-release
products
III. It falls under the category of modified release drugs
IV. It is hard to modify when filling capsules with pellets
a. I, III
 b. II, IV
c. III, IV
d. I, II
e. II, III, IV
56. The enteric coating may be:
I. pH Dependent
II. Time Dependent
III. Enzyme Dependent
IV. Temperature Dependent
a. I, IV
b. I, II, III
c. II, III, IV
d. II, III
57. True about advantages of IV drugs
I. Once a drug is administered it cannot retrieve
II. Rapid action compared with other routes of administration
III. IV administration of a drug may be lifesaving
IV. Optimum blood levels may be achieved with accuracy
a. I, II, III, IV
b. II, III, IV
c. III, IV
d. I
e. II, III
58. The following are true about sterile water for injection, USP, except:
I. Water for injection that has been sterilized
II. Intended to be used as a solvent, vehicle or flavorant for already
sterilized and packaged injectable medications.
III. Packaged in pre-filled syringes or in vials containing NMT 30 mL
IV. To be labeled “NOT FOR USE IN NEWBORNS”
a. I, II, III, IV
b. II, III, IV
c. III, IV
d. I, II
e. II, IV
59. Characteristics of particles of suspension in ideal situation include;
I. Perfectly spherical in dilute suspension
II. No collision of particles
III. Settling of particles obey Stokes’ Law
a. I, II and III
b. II and III
c. I and II
d. III only
e. I and III
60. Aluminum hydroxide gel is;
I. Prepared by chemical reaction method
II. An antacid
III. Applied externally
a. I and II
b. II and III
c. I and II
d. III only
e. I, II and III
61. Single phase gels;
I. Are made up of small inorganic particles
II. Exhibit thixotropy
III. Are those in which no apparent boundaries exist between the
dispersed phase and the dispersion medium
a. I and III
b. II and III
c. I and II
d. III only
e. I, II and III
62. Which of the following properties is undesirable in pharmaceutical suspension?
a. Thixotropy
b. Caking
c. Cracking
d. Bleeding
e. Flocculation
63. The following products require the addition of preservatives EXCEPT;
a. Syrups
b. Emulsions
c. Semisolid preparations
d. Ophthalmic products
e. Large volume parenterals
64. Which method is used in the preparation of Ipecac Syrup?
a. Solution with the aid of heat
b. Solution by agitation without the aid of heat
c. Solution by chemical reaction
d. Percolation
e. Any of these methods
65. Which of the following excipients are added to tablet formulations to provide enough
bulk for compression?
a. Glidants d. Surfactants
b. Disintegrants e. Lubricants
c. Diluents
66. Partition coefficient
I. It is the measure of the lipophilicity of a drug
II. It indicates the ability of a drug to cross the cell membrane
III. Oil-water partition coefficient gives the idea about drug’s ability to cross
the lipidic membrane
IV. It measures the amount of solute that can dissolved in one solvent
a. I, II, III and IV are correct
b. II and III are correct
c. Only IV is correct
d. I, II and III are correct
e. I and II are correct
67. The following are true about crystalline solid, except:
a. Have well-defined edges and faces
b. Diffract x-rays
c. Tend to have sharp melting point
d. NOTA
68. For orally administered drug, the dosage form used as clinical trial material for
Phase 1 is;
a. Capsule with excipients
b. Capsule containing active ingredient alone
c. Tablet without excipient
d. Tablet with excipient
e. Solution form
For ITEM 69-86: MULTIPLE CHOICE. Shade the letter of the best answer
69. Powders containing deliquescent and hygroscopic materials should be wrapped
in what kind of paper?
I. Vegetable parchment
II. Glassine paper
III. Waxed paper
A. I only D. II and III
B. III only E. I, II and III
C. I and II
70. Preservative used for soft gelatin capsules
a. Glycerin c. Sorbitol
b. 80% ethyl alcohol d. 95% ethyl alcohol
 e. Methylparaben
71. Official method of determining particle size?
a. Sieve analysis c. Coulter counter
b. Sedimentation method d. Optical microscopy
72. Point where solid A & B and liquid phase co-exist.
a. Critical point c. Triple point
b. Eutectic point d. Tie point
73. Glycerogelatin component except:
a. Medicinal substance c. Water
b. Glycerin d. Cellulose
74. Protects the contents from extraneous solid and from loss of the article under
handing, storage and distribution
a. Light resistant c. Tight
b. Hermetic d. Closed container
75. Protects the contents from contaminations by extraneous liquids.
a. Light resistant c. Tight
b. Hermetic d. Closed container
76. Protects the contents from photochemical deterioration.
a. Light resistant c. Tight
b. Hermetic d. Closed container
77. It is impervious to air or any other gas under the ordinary condition of handling,
shipment or distribution. It is often sterile.
a. Light resistant c. Tight
b. Hermetic d. Closed container
78. It is tampered resistant by design
a. Tape seal c. Shrink seal
b. Aerosol container d. Bottle seal
79. Condition for a cool place
a. 2-8°C c. Not exceeding 80°C
b. 8-15°C d. -24°C- 10°C
80. Leaching happens when there is a movement of component of container into the
contents. Sorption is when the contents adhere to the container’s molecule.
a. S1 is true, S2 is false c. S1 is false, S2 is true
b. S1&S2 are both false d. S1&S2 are both true
81. Used to dispense semi-solid dosage forms such as creams and ointments
a. Collapsible tubes c. Slide box
b. Dropper bottles d. Application bottles
82. Beeswax is used in drug cosmetics due to its ability to impart good consistency in
the product. What is its melting point?
a. 70-72% c. 68-70%
b. 64-68% d. 62-65%
83. The ff. are flavorants used in antibiotics, except:
a. Anise c. Cherry
b. Raspberry d. Maple
84. If you want to mask the bitter taste of your drug. Which one below should you
use?
a. Butterscotch c. Vanilla
b. Chocolate mint d. Citrus
85. Capsule size that can carry 195-520mg of the preparation?
a. no. 5 c. no. 2
b. no. 3 d. no. 1
86. Camphor is usually comminuted by which of the following techniques?
a. Trituration
b. Spatulation
c. Sieving
d. Pulverization by intervention
e. Micronization
 For Item 87-91: Choose the best answer.
I. Elixirs
II. Syrups
III. Spirits
IV. Tinctures
V. Aromatic water
87. These are sweetened hydroalcoholic solutions
a. Only I is correct
b. Only III is correct
c. Only II is correct
d. I and II are correct
e. I, II and III are correct
88. These are saturated aqueous solutions of volatile oils
a. I, II, III and IV are incorrect
b. III and V are correct
c. I and II are correct
d. III and IV are correct
e. Only III is incorrect
89. Hydroalcoholic or alcoholic solutions of volatile substances.
a. Only V is correct
b. Only II is correct
c. Only III is correct
d. Only I is correct
e. Only IV is correct
90. Alcoholic or hydroalcoholic solutions prepared from vegetable substances
a. I and II are incorrect
b. III and V are correct
c. I and II are correct
d. III and V are incorrect
e. A and D are true
91. A concentrated or nearly saturated aqueous solution of mostly sucrose
a. I, II, III, IV and V are correct
b. I, III, and IV are incorrect
c. V is incorrect
d. All of these are true
e. B and C are true

For ITEM 92-96: The questions and incomplete statements in this section can be
correctly answered or completed by one or more of the suggested answers.
Choose the answer, A-E.

a. All statements are true

b. Only three statements are true
c. Only two statements are true
d. Only one statement is true
e. All statements are false
92. In which of the following are true about Suspending agents
I. Carbomer and colloidal silicon dioxide are example of miscellaneous
suspending agents
II. Suspending agents are work by increasing the viscosity of the dispersion
medium
III. Suspending agents maintained the appearance of a suspension
IV. They promote particle suspension and reduce crystallization
93. Which of the following is true about sugar-based syrup?
I. Sucrose is commonly employed
II. They are glycogenetic substances
III. They are directly and indirectly converted to fructose in the body
IV. Used by patient with diabetes mellitus and patient on diet
94. In which of the following is/are correct method/s of preparing syrups?
I. Solution with the aid of heat
II. Solution by agitation without the aid of heat
III. Syrups may be prepared using percolator
IV. Syrups can be prepared by chemical reaction
95. In which of the following are true:
I. Spirits have a high alcohol content
II. Aromatic waters are used for perfume and flavoring
III. Extraction is one of the methods to prepare tinctures
IV. Lotions are commonly called Galenicals
96. In which of the following are true:
II. Belladonna tincture is prepared using percolation method
III. Compound benzoin tincture is prepared using maceration method
IV. Iodine tincture is prepared using simple solution
V. Vanilla tincture is prepared using percolation method

For ITEM 97-100: TRUE OR FALSE. Shade C if the statement is correct and shade
E if the statement is wrong.
97. Dosage forms are also known as Pharmaceuticals
98. Excipients give the formulation its unique composition and characteristic physical
appearance
99. Opaque plastic is a example of light resistant container
100. Type NP glass is used for parenteral products

"Success is not final; failure is not fatal: It is the courage to continue that counts."

Prepared by:

Shaira Gayle T. Techon, RPh

Pharmacy Department – CEU Makati