1st SEM B.

Pharm End Semester (Monsoon) Examination, 2014

Pharmaceutics-I (PHA-UG-102)
SECTION-A (MCQ)

Full marks:70 Time :3 hrs

SECTION-A
Answer all MCQs (20x1=20)
1. Capsules of tetracycline hydrochloride is never 11. Camphor, Menthol and thymol are used to prepare
advised to be taken with milk because tetracycline is
inactivated by .............present in the milk.
a. Calcium a. Eutectic powder

b. Magnesium b. Effervescence powder

c. Iron c. Compound powder

d. All above d. Efflorescence powder

2. Ergot alkaloids are contra indicated in 12. young’s formula is used for calculating the doses for
children of

a. Pregnancy a. 4-20 years of age

b. Menstruation b. Under 12 yrs of age

c. Lactating mother c. Under 25 years of age

d. All of the above d. None of these

3. Glycerine in throat paint is used as 13. Majority Of Linctuses are stable, because

a. Vehicle a. Syrup is used as base

b. Sweetening agent b. Alcohol is used as base

c. Both a and b c. Glycerine is used as base

d. None of these d. None of these.

4. Combination of acetyl choline and adrenaline is an 14. Polyethylene glycol polymer are commonly known as
example of

a. Antagonism a. Carbowaxes

b. Synergism b. Polyglycols

c. Tachyphylaxis c. Macrogols

d. None of theses d. All of the above

5. Gum acacia is used as 15. Calamine is an example of

a. Suspending agent a. Indiffusible solids
b. Emulsifying agent b. Diffusible solids
c. Thickening agent c. Hygroscopic solids
d. All of the above d. None of the above.

6. Organoleptic additives includes 16. Quinine causes ringing in the ear, it is the example of
a. Colouring agent a. Idiosyncrasy
b. Sweetening agent b. Antagonism
c. Flavouring agent c. Synergism
 d. All of the above d. Additive effect.

7. Combination of aspirin and paracetamol is an 17. The standard unit for volume in apothecaries system is
example of
a. Synergism a. Gram
b. Antagonism b. Gallon
c. Tachyphylaxis c. Grain
d. None of theses d. None of these

8. The continuous hot percolation CANNOT be used for 18. The suspension meant for external application should
have small particles because
a. Opium a. To avoid gritty feeling
b. Gum b. Cover the greater area of application
c. alkaloids c. It gives faster dissolution of solid drug
d. All of the above d. All of the above

9. The main part of prescription is 19. ......................is used to introduce the medicated
dusting powder into nasal cavities.
a. Inscription a. Insufflators
b. Superscription b. Snuff
c. Subscription c. Both a and b
d. None of the above d. None of these

10. Fractional distillation is used for the separation of 20. Barbiturates and morphine should not be given to
miscible liquids such as
a. Alcohol and water a. Asthmatic patient
b. Acetone and water b. Patient having renal failure
c. Chloroform and benzene c. Patient having liver cirrhosis
d. All of the above. d. None of these.

SECTION-B SET I
Answer six short questions from the followings: (6x5=30)

1. Calculate the % strength of alcohol which is being produced by mixing of 70% alcohol 50ml and 80% alcohol 50
ml and 50% alcohol 50 ml.
2. Calculate the dose for (i) 8 months old infants; (ii) a child of 6 years of age; (iii) a boy of 16 years of
age; (iv) A girl having 0.57 m2 of body surface area when the adult dose a drug is 100 mg.
3. Write a short note on elixir.
4. Write a short note on effervescent granules.
5. Write a short note on gargles.
6. Write a short note on displacement value for suppositories.
7. Differentiate between lotion and liniments, emulsion and suspension.
8. Write a short note on identification test on emulsions.
SECTION-C
Answer two long questions from the followings: (2x10=20)
1. Define the term ‘emulsifying agent’. Write the ideal qualities of an emulsifying agent. How will you classify the
emulsifying agent?
2. What is incompatibility? Classify it. Write notes on physical incompatibility.

3. What is posology? What are the factors influencing dose of a drug explain in details?
 EMR (SET: I)

1st SEB B. Pharm End Semester (Monsoon) Examination, 2014

Pharmaceutics-I (PHA-UG-102)
SECTION-A (MCQ)

Answers of MCQ (1x20=20)

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

A A C A D D A D A D A A A D A A B D B A

SECTION-B (SHORT TYPE) (5x6=30)

1 Solve this problem with the method of allegation.

2 Use different formula for child dose calculation.

3 Write composition, use special characteristics of elixir

4 Write composition, use special characteristics and chemical reaction involved in effervescent granules.

5 Write composition, use special characteristics of gargles.

6 Write definition and explain how it is being calculated.

7 Write only the distinct differences.

8 Discuss about only identification test for emulsion.

SECTION-C (LONG TYPE) (10x2=20)

1 Definition, ideal qualities and classification of emulsifying agent.

2 Definition, classification and physical incompatibility.

3 Write definition and factors influencing dose of a drug with proper examples.