Antianginal and Cerebrovascular

Drugs
Main
Dosage and Mechanism of Main Indications Side Effects of
Drug Contraindications
Application form Action for Use the Drug
for use
Nitroglycerine is
contraindicated
Nitroglycerine is
in patients with
mainly used to
hypotension (low
treat angina
blood pressure),
Nitroglycerine is (chest pain)
increased
a vasodilator caused by
intracranial Common side
that works by coronary artery
pressure, and effects of
relaxing the disease. It can
severe anaemia. nitroglycerine
Sublingual smooth muscles also be used in
It should not be include
Nitroglycerine tablets, spray, in blood vessels, the
used in patients headache,
ointment which increases management of
taking dizziness,
blood flow and heart failure,
medications for flushing, and
reduces the acute
erectile hypotension.
workload on the myocardial
dysfunction, such
heart. infarction (heart
as sildenafil
attack), and
(Viagra), tadalafil
pulmonary
(Cialis), and
hypertension.
vardenafil
(Levitra).

Antianginal and Cerebrovascular Drugs 1

 Main
Dosage and Mechanism of Main Indications Side Effects of
Drug Contraindications
Application form Action for Use the Drug
for use
Sustak is
contraindicated
in patients with
hypotension (low
Sustak contains
blood pressure),
isosorbide
increased
dinitrate, which
intracranial
is a vasodilator Common side
Sustak is mainly pressure, and
that works by effects of Sustak
used to treat severe anaemia.
relaxing the include
Sublingual angina (chest It should not be
Sustak smooth muscles headache,
tablets pain) caused by used in patients
in blood vessels, dizziness,
coronary artery taking
which increases flushing, and
disease. medications for
blood flow and hypotension.
erectile
reduces the
dysfunction, such
workload on the
as sildenafil
heart.
(Viagra), tadalafil
(Cialis), and
vardenafil
(Levitra).
Amlodipine is
Amlodipine is a
contraindicated
calcium channel Amlodipine is
in patients with Common side
blocker that mainly used to
hypotension (low effects of
works by treat
blood pressure) amlodipine
relaxing the hypertension
and aortic include
smooth muscles (high blood
Amlodipine Oral tablets stenosis headache,
in blood vessels, pressure) and
(narrowing of the dizziness,
which increases angina (chest
heart valve). It flushing, and
blood flow and pain) caused by
should be used oedema
reduces the coronary artery
with caution in (swelling).
workload on the disease.
patients with liver
heart.
disease.

Antianginal and Cerebrovascular Drugs 2

 Main
Dosage and Mechanism of Main Indications Side Effects of
Drug Contraindications
Application form Action for Use the Drug
for use
Atenolol is
contraindicated
Atenolol is a Atenolol is
in patients with
beta blocker that mainly used to
bradycardia
works by treat Common side
(slow heart rate),
blocking the hypertension effects of
heart block, and
effects of (high blood atenolol include
cardiogenic
Atenolol Oral tablets adrenaline on pressure), fatigue,
shock. It should
the heart and angina (chest dizziness,
be used with
blood vessels, pain), and bradycardia, and
caution in
which reduces arrhythmias hypotension.
patients with
heart rate and (abnormal heart
asthma,
blood pressure. rhythms).
diabetes, and
liver disease.

Pentoxifylline is
mainly used to
treat peripheral
Pentoxifylline is
vascular
contraindicated
disease,
in patients with
Pentoxifylline is including
recent bleeding, Common side
a intermittent
retinal bleeding, effects of
hemorheological claudication
and severe pentoxifylline
agent that works (pain in the legs
Pentoxifylline Oral tablets bleeding include nausea,
by improving when walking). It
disorders. It vomiting,
blood flow and can also be
should be used headache, and
reducing blood used in the
with caution in dizziness.
viscosity. management of
patients with liver
cerebrovascular
and kidney
disease, diabetic
disease.
neuropathy, and
Raynaud's
disease.

Antianginal and Cerebrovascular Drugs 3

 Main
Dosage and Mechanism of Main Indications Side Effects of
Drug Contraindications
Application form Action for Use the Drug
for use

Sumatriptan is
contraindicated
Sumatriptan is a
in patients with Common side
serotonin
ischemic heart effects of
receptor agonist Sumatriptan is
disease, angina, sumatriptan
Oral tablets, that works by mainly used to
and uncontrolled include nausea,
Sumatriptan nasal spray, constricting treat migraines
hypertension. It vomiting,
injection blood vessels in and cluster
should be used dizziness, and
the brain and headaches.
with caution in injection site
reducing
patients with liver reactions.
inflammation.
and kidney
disease.
Vinpocetine is
Vinpocetine is a Vinpocetine is contraindicated
cerebral mainly used to in patients with
vasodilator that improve hypotension (low Common side
works by cognitive blood pressure) effects of
increasing blood function and and bleeding vinpocetine
Vinpocetine Oral tablets
flow to the brain memory in disorders. It include nausea,
and improving patients with should be used abdominal pain,
oxygen and cerebrovascular with caution in and dizziness.
glucose uptake disease and patients with liver
by brain cells. dementia. and kidney
disease.
Nicergoline is
mainly used to
Nicergoline is
treat peripheral
contraindicated
vascular
in patients with
disease,
Nicergoline is an recent bleeding, Common side
including
ergot derivative retinal bleeding, effects of
intermittent
that works by and severe nicergoline
claudication
Nicergoline Oral tablets improving blood bleeding include nausea,
(pain in the legs
flow and disorders. It vomiting,
when walking). It
reducing blood should be used headache, and
can also be
viscosity. with caution in dizziness.
used in the
patients with liver
management of
and kidney
cerebrovascular
disease.
disease and
dementia.

Antianginal and Cerebrovascular Drugs 4

 Main
Dosage and Mechanism of Main Indications Side Effects of
Drug Contraindications
Application form Action for Use the Drug
for use
Trimetazidine is
mainly used to Trimetazidine is
treat angina contraindicated
Trimetazidine is
(chest pain) in patients with Common side
a metabolic
caused by Parkinson's effects of
agent that works
coronary artery disease and trimetazidine
by improving
Trimetazidine Oral tablets disease. It can severe renal include nausea,
energy
also be used in impairment. It vomiting,
metabolism in
the should be used headache, and
heart and brain
management of with caution in dizziness.
cells.
heart failure and patients with liver
tinnitus (ringing disease.
in the ears).

Antianginal and Cerebrovascular Drugs 5