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HOLY ANGEL UNIVERSITY

#1 Holy Angel Avenue, Sto. Rosario, Angeles City Philippines 2009


Telefax: 888-2514 /888-1754 /888-1290/ local 1190

Email Address: hau@hau.edu.ph
Website: http://www.hau.edu.ph

DRUG STUDIES

Name of the Drug Classification Therapeutic Effect Side Effects Adverse Effect Nursing Responsibility

General: Epinephrine alpha- and beta- Epinephrine usage  Increased heart  Severe Before:
adrenergic agonists depends on specific rate hypertension  Verify patient’s
(sympathomimetic indication but it can be  Elevated blood  Arrhythmias identity
Brand: Adrenalin, agents) used in the operating pressure  Myocardial  Assess patient’s
EpiPen room for treatment of  Anxiety and ischemia medical history
anaphylaxis (for severe restlessness  Cerebral to see if it is safe
Route of allergic reaction) ,  Headache hemorrhage for them to take
Administration: cardiac arrest (to  Nausea and  Pulmonary epinephrine
IV, SC, IM increase coronary and Vomiting edema
cerebral blood flow),  Tremors  Tissue necrosis During:
Dosage: hypotension (to increase  Perform the 10
Initial adult dose blood pressure and rights of
(anaphylaxis) cardiac output), and medication
0.3 to 0.5 mg given local vasoconstriction administration
intramuscularly (IM) or (often added to local  Monitor the
subcutaneously (SC). For anesthetics to improve patient for any
pediatric patients, the their effectiveness and signs of adverse
recommended initial prolong their duration). reactions, such
dose is 0.01 mg/kg (up as allergic
reactions,
to a maximum of 0.3 to arrhythmias,
0.5 mg) given IM or SC. respiratory
difficulties.
Cardiac arrest  Monitor the
In the case of cardiac patient's blood
arrest, the pressure, heart
recommended dose of rate, and oxygen
epinephrine is 1 mg saturation levels
given intravenously (IV) during
every 3 to 5 minutes administration.
during resuscitation
efforts. After:
 Monitor the
patient for at
least 30 minutes
for any ongoing
side effects or
complication.
 Monitor patient
closely for any
lingering effects
of epinephrine,
such as
hypertension or
arrhythmias, as
well as for any
other
postoperative
complications.

References:
Epinephrine Injection: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a603002.html

Katiboina, V. (2022, August 4). Epinephrine: Generic, Uses, Side Effects, Dosages, Interactions & Warnings. RxList. https://www.rxlist.com/epinephrine/generic-
drug.htm

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