HOLY ANGEL UNIVERSITY

#1 Holy Angel Avenue, Sto. Rosario, Angeles City Philippines 2009

Telefax: 888-2514 /888-1754 /888-1290/ local 1190

Email Address: hau@hau.edu.ph
Website: http://www.hau.edu.ph

DRUG STUDIES

Name of the Drug Classification Therapeutic Effect Side Effects Adverse Effect Nursing Responsibility

General: Ondansetron Serotonin 5-HT3 Ondansetron is a  Headache  Allergic reactions Before:

receptor antagonists; medication commonly  Fatigue or (e.g., rash, hives,  Verify patient’s
Antiemetic used in the operating drowsiness itching, difficulty identity
Brand: Zofran room to prevent nausea  Constipation breathing)  Assess patient’s
and vomiting associated  Diarrhea  Abnormal heart medical history
Route of with surgery and  Dizziness rhythm to see if it is safe
Administration: anesthesia.  Dry mouth  Seizures for them to take
IV, ODT  Flushing or  Blurred vision ondansetron
warmth  Unusual
Dosage:  Injection site tiredness or During:
Adults (PONV) reactions (pain, weakness  Perform the 10
redness, or  Chest pain or rights of
4mg IV swelling) tightness medication
 Fainting administration
Children:  Monitor the
patient for any
0.1-0.3 mg/kg signs of adverse
reactions, such
as allergic
reactions or
 abnormal heart
rhythm.
 Monitor the
patient's blood
pressure, heart
rate, and oxygen
saturation levels
during
administration.

After:
 Monitor the
patient for at
least 30 minutes
for any ongoing
side effects or
complication.
 Monitor
Cardiovascular
status.
 Monitor for fluid
and electrolyte
status.

References:

ONDANSETRON HYDROCHLORIDE. (n.d.). http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/O010.html

Ondansetron: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a601209.html

Zofran (Ondansetron): Uses, Interactions & Side Effects | Cleveland Clinic. (n.d.). Cleveland Clinic. https://my.clevelandclinic.org/health/drugs/18477-ondansetron-
solution